5. Any obstructive causes from PUJ to VUJ
intra-luminal ,luminal or extra-luminal
CONGENITAL
INFLAMMATORY
NEOPLASTIC
TRAUMATIC
STONES
Obstructive causes
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6. Reflux causes
Urine reflux through the UVJ into the ureter upwards the
kidney
Primary vesico-ureteral reflux:
Secondary vesico-ureteral reflux:
infra-vesical obstructions from the bladder neck down to the
external urethral meatus.
CONGENITAL
INFLAMMATORY
NEOPLASTIC
TRAUMATIC
STONES
• NEUROGENIC
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7. Pathogenesis :
Presence of obstruction or reflux will result in
a volume overload which leads to gradual
increase in the intracalyceal pressure which
will lead to compression of the blood supply
resulting in parenchymal ischemia that ends
by parenchymatous atrophy.
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8. course and stages
1. Mild hydronephrosis : Renal calyces become flat then clubbed
and lately become ballooned; the parenchyma between the
minor calyces are thinned out but is still present i.e. the
kidney still has minor and major calyces.
2. Moderate hydronephrosis : the parenchyma between the
calyces are eaten up so the kidney becomes with major
calyces without minor calyces.
3. Advanced hydronephrosis : Both minor and major calyces are
lost and the kidney becomes as a sac of urine.
Functioning.
Non functioning.
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9. Terms according to extent of dilatation:
Hydrocalyx : Dilatation of a renal calyx.
Hydropelvis: Dilatation of the renal pelvis.
Hydronephrosis: Dilatation of the pelvi-calyceal system.
Hydroureter: Dilatation of the ureter.
Hydro-uretero-nephrosis: Dilatation of both the ureter and
kidney
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10. Clinical manifestations
Obstructive cases :
Colicky pain:
Renal pain:
Renal swelling
Gastro-intestinal manifestations : As dyspepsia.
Manifestations of complications : e.g. ruptured kidney,
infections, hematonephrosis.
Manifestations of chronic renal failure:
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11. Reflux cases
LUTs /BPH
Chronic retention : gradual increase in the
amount of residual urine inside the bladder
Chronic retention with overflow incontinence.
Renal pain.
Renal infections.
Renal swelling : The kidney size is normal or
slightly enlarged
Chronic Renal Failure manifestation
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12. Characteristics of hydronephrotic swelling by
examination:
• Oblong lobulated surface cystic with
rounded borders.
• Felt in the loin, or can be pushed in
the loin.
• Directed downwards.
• The hand can be insinuated between
it and the costal margin
• ballotable mass
• renal contact.
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13. Investigations :
- RADIOLOGICAL
- LABORATORY
laboratory :
Urine analysis and culture and sensitivity test
Renal function testes
Electrolytes( Na K Ph)
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14. Radiological
Abdominal ultrasonography
Plain X-Ray urinary tract (KUB film)
CT-UT with or without contrast
Intravenous urography (IVU)
Voiding cystourethrography(VCUG) :
Antegrade nephrostography or Retro-grade
pyelography:
MRU
Renogram
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45. Treatment of hydronephrosis :
According to :
Unilateral hydronephrosis
Bilateral hydronephrosis
Solitary kidney
Compensated patient
decompensate patient
Functioning or non Functioning
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46. Patient with a solitary kidney
Compensated patient : Treatment of the
cause.
Decompensated patient
Urinary diveration (PCN or JJ)
Dialysis + (PCN or JJ)
Then
treatment of the cause.
Regular dialysis and renal transplantation
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47. Unilateral hydronephrosis :
Functioning kidney:
Treatment of the cause.
Non-functioning kidney :
± Nephrectomy
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48. Bilateral hydronephrosis :
Decompensated patient :
± Dialysis + PCN treatment of the cause.
We can begin with ;
The better side, if equally affected, begin with
The painful side, if equally affected, begin with
The infected side.
Regular dialysis and renal transplantation
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49. Bilateral hydronephrosis :
1. Compensated patient :
Treatment of the cause and we begin with ;
The worst side, but if equally affected , we begin with
The painful side, but if equally affected, we begin with
The infected side.
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