A 20-year-old woman presented with fever, fatigue, and weight loss. She had a history of Holt-Oram syndrome and primary EBV infection a year prior. Testing showed pancytopenia, hepatosplenomegaly, and elevated ferritin. A bone marrow biopsy showed hemophagocytosis. She was diagnosed with EBV-associated hemophagocytic syndrome and died despite treatment. Hemophagocytic syndrome is caused by impaired NK and cytotoxic T cell function leading to uncontrolled immune activation and cellular damage. It can be genetic, infection-associated, malignancy-associated, or associated with autoimmune diseases. Treatment involves controlling inflammation, the underlying trigger, and supportive care.
Hemophagocytic Lymphohistiocytosis (HLH) is an aggressive and life threatening syndrome which results from excessive immune activation, that can rapidly deteriorate and lead to multiple organ failure and death.
Hemophagocytic lymphohistiocytosis (HLH) is not an uncommon disorder. It should be actively considered when we have an acutely ill child with fever, organomegaly, rapidly evolving cytopenias and deranged liver functions. It is a life-threatening disease characterized by uncontrolled hyperinflammation on the basis of a variety of inherited or acquired immune deficiency. Paediatricians, especially in the tertiary care setting, need to be sensitized about its clinical symptoms and diagnostic criteria so that we can offer timely treatment. This article characterizes this condition in detail and outlines its treatment.
Hemophagocytic Lymphohistiocytosis (HLH) is an aggressive and life threatening syndrome which results from excessive immune activation, that can rapidly deteriorate and lead to multiple organ failure and death.
Hemophagocytic lymphohistiocytosis (HLH) is not an uncommon disorder. It should be actively considered when we have an acutely ill child with fever, organomegaly, rapidly evolving cytopenias and deranged liver functions. It is a life-threatening disease characterized by uncontrolled hyperinflammation on the basis of a variety of inherited or acquired immune deficiency. Paediatricians, especially in the tertiary care setting, need to be sensitized about its clinical symptoms and diagnostic criteria so that we can offer timely treatment. This article characterizes this condition in detail and outlines its treatment.
PPI-INDUCED BICYTOPENIA: MATTER OF CONCERN by RxVichuZ! ;)RxVichuZ
This presentation deals with bicytopenia induced by proton pump inhibitors, that were reported and published as a Case Report by researchers from China.
References have been provided as a separate textbox under each slide, for extensive referencing into the same.
Austin Arthritis is an open access, peer reviewed, scholarly journal dedicated to publish articles covering all areas of Arthritis.
The journal aims to promote research communications and provide a forum for doctors, researchers, physicians and healthcare professionals to find most recent advances & happenings in all areas of Arthritis. Austin Arthritis accepts original research articles, reviews, mini reviews, case reports and rapid communication covering all aspects of Arthritis.
Austin Arthritis strongly supports the scientific up gradation and fortification in related scientific research community by enhancing access to peer reviewed scientific literary works. Austin Publishing Group also brings universally peer reviewed journals under one roof thereby promoting knowledge sharing, mutual promotion of multidisciplinary science
Graft versus host disease (GVHD) is an immune mediated disease due to complex interaction between donor (lymphoid tissue) and recipient’s immunity occurring after transplantation.
Two types
Acute (less than 100 days)
Chronic (more than 100 days)
PPI-INDUCED BICYTOPENIA: MATTER OF CONCERN by RxVichuZ! ;)RxVichuZ
This presentation deals with bicytopenia induced by proton pump inhibitors, that were reported and published as a Case Report by researchers from China.
References have been provided as a separate textbox under each slide, for extensive referencing into the same.
Austin Arthritis is an open access, peer reviewed, scholarly journal dedicated to publish articles covering all areas of Arthritis.
The journal aims to promote research communications and provide a forum for doctors, researchers, physicians and healthcare professionals to find most recent advances & happenings in all areas of Arthritis. Austin Arthritis accepts original research articles, reviews, mini reviews, case reports and rapid communication covering all aspects of Arthritis.
Austin Arthritis strongly supports the scientific up gradation and fortification in related scientific research community by enhancing access to peer reviewed scientific literary works. Austin Publishing Group also brings universally peer reviewed journals under one roof thereby promoting knowledge sharing, mutual promotion of multidisciplinary science
Graft versus host disease (GVHD) is an immune mediated disease due to complex interaction between donor (lymphoid tissue) and recipient’s immunity occurring after transplantation.
Two types
Acute (less than 100 days)
Chronic (more than 100 days)
Human papiloma virus and its association to Cervical Cancer
HPV in Saudi Arabia .
Currently I am working in Arar Central Hospital, in Arar city
In Saudi Arabia.
Please do not hesitate to contact us if you require any further information.
Alsultany@hotmail.com
describe the tumor suppressor genes and examples for downloading the presentation, more presentations , infographics and blogs visit :
studyscienceblog.wordpress.com
This presentation delves into another commonly missed diagnosis in people with multiple symptoms that persist despite usual medical care. Mast Cell Disorders may help point you or your doctor to a correct diagnosis and a successful integrative care plan.
Coagulation: In medicine, the clotting of blood. The process by which the blood clots to form solid masses, or clots.
More than 30 types of cells and substances in blood affect clotting. The process is initiated by blood platelets. Platelets produce a substance that combines with calcium ions in the blood to form thromboplastin, which in turn converts the protein prothrombin into thrombin in a complex series of reactions. Thrombin, a proteolytic enzyme, converts fibrinogen, a protein substance, into fibrin, an insoluble protein that forms an intricate network of minute threadlike structures called fibrils and causes the blood plasma to gel. The blood cells and plasma are enmeshed in the network of fibrils to form the clot.
My son had Wiskott Aldrich Syndrome (WAS). He had a bone marrow transplant in August 2006. His WAS is healed. This presentation was designed by some grad students. Some of the content is from my blog and it pictures my son, David. http://www.davidmcnally.blogspot.com
Evan Syndrome A Case Report by Parimala L | P Anjaneyuluijtsrd
Evan syndrome is an autoimmune disorder in which auto antibodies are directed against antigens specific to red blood cells, platelets, and neutrophils. Also known as Immune mediated thrombocytopenia ITP , Autoimmune hemolytic anemia AIHA , or immune pancytopenia. Clinical symptoms are thrombocytopenia, hemolysis, and severe anemia. The first line treatment for Evan syndrome intravenous corticosteroids or intravenous immunoglobulins and the second line treatment with rituximab or mycophenolate mofetil or splenectomy for those who are refractory to steroids. We report the case of a 35 year old female who presented with high grade fever with chills and rigors associated with hematuria and she has undergone a diagnosis of Evan Syndrome. Parimala L | P Anjaneyulu "Evan Syndrome: A Case Report" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-1 , February 2024, URL: https://www.ijtsrd.com/papers/ijtsrd62406.pdf Paper Url: https://www.ijtsrd.com/medicine/other/62406/evan-syndrome-a-case-report/parimala-l
Drug reaction with eosinophilia and systemic symptoms & acute generalized exanthematous pustulosis 2019
Presented by Nattasasi Suchamalawong, MD.
November 15, 2019
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
17. (A) Haematoxylin-eosin stain of bone marrow sample obtained on autopsy showing rare phagocytic cells with engulfed haematopoietic elements (arrows). (B) CD68 (macrophage marker) staining by immuno-histochemistry showing presence of abundant macrophages within lymph nodes. (C) EBV staining by immuno-histochemistry showing numerous infected cells (arrows) within lymph node.
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