What is Glycoprotein ?:
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to polypeptide side-chains.
This process is known as glycosylation.
The carbohydrate is attached to the protein during the following modifications: Co-translational modification & Post-translational modification.
In proteins that have segments extending extracellularly, the extracellular segments are often glycosylated.
What is Glycoprotein ?:
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to polypeptide side-chains.
This process is known as glycosylation.
The carbohydrate is attached to the protein during the following modifications: Co-translational modification & Post-translational modification.
In proteins that have segments extending extracellularly, the extracellular segments are often glycosylated.
Formation of heamoglobin / B.pharmacy 2 semesterKondal Reddy
Haemoglobin, is the iron-containing oxygen-transport metalloprotein in the red blood cells (erythrocytes) of almost all vertebrates as well as the tissues of some invertebrates.
Haemoglobin in blood carries oxygen from the lungs to the rest of the body.
Haemoglobin develops in cells in the bone marrow that become red blood cells. When red cells die, haemoglobin is broken up: iron is removed and transported to the bone marrow by proteins called transferrins, and used again in the production of new red blood cells.
Formation of heamoglobin / B.pharmacy 2 semesterKondal Reddy
Haemoglobin, is the iron-containing oxygen-transport metalloprotein in the red blood cells (erythrocytes) of almost all vertebrates as well as the tissues of some invertebrates.
Haemoglobin in blood carries oxygen from the lungs to the rest of the body.
Haemoglobin develops in cells in the bone marrow that become red blood cells. When red cells die, haemoglobin is broken up: iron is removed and transported to the bone marrow by proteins called transferrins, and used again in the production of new red blood cells.
The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.
It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach various sugar monomers to proteins as the proteins move through the apparatus.
here u will find every detail of golgi.
Collagen is most abundant protein in mammals, the main fibrous component of skin, bone, tendon and cartilage.
Collagen comprises one- third of the total protein, accounts for three-quarters of the dry weight of skin, and is the most prevalent component of the extracellular matrix.
The collagen family consists of 28 members and these are classified by Roman numbers on the basis of their chronology of discovery.
Coronavirus disease 2019 (COVID-19). Complete information on coronavirus. Introduction, history, symptoms, covid19 structure, S protein of coronavirus, M proteins of coronavirus, spreading variations of coronavirus, vaccines, drugs to control coronavirus.
FOXP2 gene mutated in a speech and language disorder.
In humans, mutation of ‘FOXP2’ gene, results in a severe developmental disorder that significantly disrupts speech and language skills.
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Executive Directors Chat Leveraging AI for Diversity, Equity, and InclusionTechSoup
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
2. Introduction:
Golgi is made up of a series of flattened sacs called cisternae.
The Golgi complex, functions as a factory in which proteins and
lipids received from the ER are further processed and sorted.
After processing the protein or lipids transport to their
destinations: lysosomes endosomes and plasma membrane.
3. The Golgi apparatus was one of the first organelles to be
discovered and observed in detail.
It was discovered in 1898 by Italian physician Camillo Golgi during
an investigation of the nervous system.
5. STRUCTURE OF GOLGI:
Golgi complex consisting of two main networks: the cis Golgi
network (CGN) and the trans Golgi network (TGN).
Proteins from the ER enter at its cis face (entry face), which is
convex and usually oriented toward the nucleus.
They are then transported through the Golgi and exit from its
concave trans face (exit face).
6. Protein processing within the Golgi:
Protein processing within the Golgi involves the modification and
synthesis of the carbohydrate portions of glycoproteins.
One of the major aspects of this processing is the modification of
the N-linked oligosaccharides.
Plasma membrane proteins is the best example for N-linked
oligosaccharides modification in Golgi apparatus.
7. The first modification is the removal of three mannose molecules,
this is followed by the sequential addition of an one N-
acetylglucosamine.
The second modification is removal of two more mannoses, and
the addition of a fucose and two more N-acetylglucoseamines.
Finally, three galactose and three sialic acid residues are added.
8. The enzymes that carry out the addition of sugar residues, is the
glycosyltransferases.
The enzymes that are responsible for the removal of sugars are
glycosidases.
9.
10. Lipid Metabolism in the Golgi:
The glycerol phospholipids, cholesterol, and ceramide are
synthesized in the SER.
Sphingomyelin and glycolipids are then synthesized from
ceramide in the Golgi apparatus.
Sphingomyelin (the only non-glycerol phospholipid in cell
membranes) is synthesized by Golgi.
11. Protein and lipids export from the Golgi Apparatus:
Proteins as well as lipids and polysaccharides are transported from
the Golgi apparatus to their final destinations through the
secretory pathway.
This involves the sorting of proteins into different kinds of
transport vesicles, which bud from the trans Golgi network and
deliver their contents to the appropriate cellular locations.
