This document discusses the management of tibial diaphysis gap nonunions. Gap nonunions present a major challenge due to associated infection, previous surgeries, and bone loss. The key principles of treatment include managing any infection through debridement and antibiotics, achieving bone union through techniques like cancellous bone grafting or the Masquelet technique, and addressing soft tissue coverage and deformities. Successful treatment may require multiple reconstructive surgeries using methods like the Ilizarov technique to gradually regenerate bone between fragments.