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Extracellular matrix
The extracellular matrix surrounds animal cells outside of their plasma membranes, filling spaces between cells and adhering them together. It consists of secreted proteins and polysaccharides found most abundantly in connective tissues. One example is the basal lamina, a thin sheet on which epithelial cells rest that surrounds muscle, fat, and nerve cells. The differences in extracellular matrices result from variations in types, amounts, and organization of their major components: matrix proteins, polysaccharides, and adhesion proteins. The pattern of the extracellular matrix regulates key cell processes like polarity, division, adhesion, motility, development, migration, and differentiation by responding to growth factors.
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Extracellular matrix
- 1. DR SUJIT GHOSH JK COLLEGE PURULIA EXTRACELLULAR MATRIX
- 2. ECM Animal cellsare surrounded by extracellular matrix beyond the immediate vicinity of their plasma membrane, filling spaces between cells and adhering cells together. Extracellular matrices are of various types consisting of secreted proteins and polysaccharides and are most abundant in connective tissues. One of the examples of extracellular matrix is the basal laminae. It is a continuous sheet of 50 to 200 nm thickness and on top of which a thin layer of epithelial cells rest. Such basal laminae surround muscle cells, adipose cells, and peripheral nerves. The differences between various types of extracellular matrices result from both quantitative variations in the types or amounts of these different constituents and from modifications in their organization. The three major components of extracellular matrix are matrix proteins, matrix polysaccharides and the matrix adhesion proteins.
- 3. SUPPORT FOR CELLS PATTERNOF ECM REGULATES polarity cell division adhesion motility DEVELOPMENT migration differentiation growth factors
- 5.