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Page 1
Gerard P. Aurigemma MD
Board Review Course 2017
Echo in Ischemic Heart
Disease and Myocardial
Infarction
Echo and CAD
• Regional wall motion abnormalities at rest may not
be seen until the luminal diameter stenosis exceeds
85%
– with exercise, a coronary lesion of 50% can result in
regional dysfunction
• Echocardiography can overestimate the amount of
ischemic or infarcted myocardium, as wall motion of
adjacent regions may be affected by:
– Tethering
– Disturbance of regional loading conditions
– Stunning
• Wall thickening and motion should be considered
• Regional wall motion abnormalities may occur in the
absence of CAD
Page 2
ASE Guidelines 2005
ASE Guidelines 2005
Page 3
Page 4
7
Case #1
Page 5
Case #1
Case #1
Page 6
Case #2
Page 7
Case #2
Page 8
15
Diagnostic Role in Acute MI
• Regional wall motion
abnormality
– Occurs within 5-10
beats of acute coronary
ligation
– Rate and amplitude of
endocardial excursion
decreased
– Reduced wall
thickening or wall
thinning
Page 9
Which of the following patients has the acute MI?
A B C
1. Patient A
2. Patient B
3. Patient C
4. All of the above
5. None of the above
Page 10
What is the diagnosis?
1. LAD territory infarction with a
septal aneurysm
2. LAD ischemia but no aneurysm
3. Volume loaded LV due to left
sided valve disease
4. None of the above
Violent LBBB
Page 11
Page 12
Courtesy Rick
Grimm, Cleveland
Clinic Foundation
G:GPAslides.3
70 year old woman, complains of indigestion
for 1 day then collapse
Admitted to MICU with shock
Fellow is called to do an echo
Page 13
G:GPAslides.3
G:GPAslides.3
What can be said with
confidence about this
patient’s diagnosis?
1. She likely has a
large MI
2. She probably has an
RCA occlusion
3. Shock is due to LV
dysfunction
4. This is probably her
first coronary event
Page 14
Page 15
G:GPAslides.3
Papillary muscle rupture
Clinical features
• Rare complication of acute MI
• New systolic murmur and CHF day 3 to 5
post-MI
• Usually (82%) first coronary event in patient
without collateral circulation; 50% 1 vessel
disease
• Often small area of necrosis
• Poor prognosis (90% mortality) and depends
on extent of rupture
G:GPAslides.3
Papillary muscle rupture
• Posteromedial
papillary muscle
6-12x more common
• anterolateral
papillary muscle has
LAD and LCx supply
• Usually single head
rupture
Papillary muscle
head
Papillary muscle
base
Page 16
Page 17
Ventricular Aneurysm
Echocardiographic features
• LV cavity shape distorted
during
diastole and systole
• Wall thin and motion
paradoxical
• Wide-neck typically with neck
diameter = aneurysm diameter
• Hinge points connecting site
with contractile myocardium
may be seen
• Sensitivity of echo: 93 to
100%
• 85 to 95% involve cardiac
apex
• Thrombus present in 34%
Aneurysm Pseudoaneurysm
Page 18
G:GPAslides.3
Left ventricular pseudoaneurysm: Clinical
and pathologic features
Myocardial rupture contained
by adherent parietal
pericardium and thrombus
Small, narrow-neck channel
connecting ventricle and
aneurysm sac
Walls of the pseudoaneurysm
composed of pericardium
rather than thin-walled
myocardial scar of true
aneurysm
pseudoaneurysm
Page 19
Page 20
G:GPAslides.3
Right Ventricular Infarction
Commonly accompanies LV inferior MI (25% -33%)
Results from occlusion of RCA proximal to the RV
marginal branches, LCX, or apex of RV from
“wrap-around” LAD
Hemodynamics characterized by disproportionate
elevation of right-sided filling pressures with
reduced cardiac output
EKG: V4R ST
elevation sensitive
and specific

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Echo in ischaemic heart disease and Myocardial infarction

  • 1. Page 1 Gerard P. Aurigemma MD Board Review Course 2017 Echo in Ischemic Heart Disease and Myocardial Infarction Echo and CAD • Regional wall motion abnormalities at rest may not be seen until the luminal diameter stenosis exceeds 85% – with exercise, a coronary lesion of 50% can result in regional dysfunction • Echocardiography can overestimate the amount of ischemic or infarcted myocardium, as wall motion of adjacent regions may be affected by: – Tethering – Disturbance of regional loading conditions – Stunning • Wall thickening and motion should be considered • Regional wall motion abnormalities may occur in the absence of CAD
  • 2. Page 2 ASE Guidelines 2005 ASE Guidelines 2005
  • 8. Page 8 15 Diagnostic Role in Acute MI • Regional wall motion abnormality – Occurs within 5-10 beats of acute coronary ligation – Rate and amplitude of endocardial excursion decreased – Reduced wall thickening or wall thinning
  • 9. Page 9 Which of the following patients has the acute MI? A B C 1. Patient A 2. Patient B 3. Patient C 4. All of the above 5. None of the above
  • 10. Page 10 What is the diagnosis? 1. LAD territory infarction with a septal aneurysm 2. LAD ischemia but no aneurysm 3. Volume loaded LV due to left sided valve disease 4. None of the above Violent LBBB
  • 12. Page 12 Courtesy Rick Grimm, Cleveland Clinic Foundation G:GPAslides.3 70 year old woman, complains of indigestion for 1 day then collapse Admitted to MICU with shock Fellow is called to do an echo
  • 13. Page 13 G:GPAslides.3 G:GPAslides.3 What can be said with confidence about this patient’s diagnosis? 1. She likely has a large MI 2. She probably has an RCA occlusion 3. Shock is due to LV dysfunction 4. This is probably her first coronary event
  • 15. Page 15 G:GPAslides.3 Papillary muscle rupture Clinical features • Rare complication of acute MI • New systolic murmur and CHF day 3 to 5 post-MI • Usually (82%) first coronary event in patient without collateral circulation; 50% 1 vessel disease • Often small area of necrosis • Poor prognosis (90% mortality) and depends on extent of rupture G:GPAslides.3 Papillary muscle rupture • Posteromedial papillary muscle 6-12x more common • anterolateral papillary muscle has LAD and LCx supply • Usually single head rupture Papillary muscle head Papillary muscle base
  • 17. Page 17 Ventricular Aneurysm Echocardiographic features • LV cavity shape distorted during diastole and systole • Wall thin and motion paradoxical • Wide-neck typically with neck diameter = aneurysm diameter • Hinge points connecting site with contractile myocardium may be seen • Sensitivity of echo: 93 to 100% • 85 to 95% involve cardiac apex • Thrombus present in 34% Aneurysm Pseudoaneurysm
  • 18. Page 18 G:GPAslides.3 Left ventricular pseudoaneurysm: Clinical and pathologic features Myocardial rupture contained by adherent parietal pericardium and thrombus Small, narrow-neck channel connecting ventricle and aneurysm sac Walls of the pseudoaneurysm composed of pericardium rather than thin-walled myocardial scar of true aneurysm pseudoaneurysm
  • 20. Page 20 G:GPAslides.3 Right Ventricular Infarction Commonly accompanies LV inferior MI (25% -33%) Results from occlusion of RCA proximal to the RV marginal branches, LCX, or apex of RV from “wrap-around” LAD Hemodynamics characterized by disproportionate elevation of right-sided filling pressures with reduced cardiac output EKG: V4R ST elevation sensitive and specific