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Intravascular
ultrasound
(IVUS)
______________________________________________________
Dr. Sayeedur Rahman Khan Rumi
dr.rumibd@gmail.com
MD (Cardiology) Final Part Student
National Heart Foundation Hospital and Research Institute
Introduction
• Intravascular ultrasound (IVUS) catheters use
reflected sound waves to visualize the arterial wall
in a two-dimensional, tomographic format,
analogous to a histologic cross section.
• This offers the opportunity to gather diagnostic
information about the process of atherosclerosis
and to directly observe the effects of various
interventions on the plaque and arterial wall.
Imaging Systems
Two types of IVUS systems exist, both utilizing 20- to
40-MHz silicon piezoelectric crystals:
A. Mechanical system that relies on a rotating
internal cable, and
B. Solid-state system externally mounted on a
catheter and controlled electronically
Diagrams of the two basic imaging catheter designs,
solid state (A) and mechanical (B)
• With the mechanical systems, the imaging core
rotates via a flexible drive shaft to sweep the
transducer continuously through a 360-degree arc
in the vessel.
• The solid-state catheter has 64 ultrasound
transducers arranged circumferentially around the
catheter tip and sequentially activated to produce a
360-degree image.
• Both IVUS catheters range in size from 3.2 F to 3.5 F
and have a tapered tip and shaft.
• They are designed to fit through a 6 F guide
catheter.
• The IVUS catheter connects to a console, which
displays and records the images digitally.
• Images from both systems are displayed in a
tomographic, real-time video format.
• Currently, IVUS has a resolution of approximately
100 to 150 μm.
Common clinical applications
for IVUS
1. Assessment of lesion calcium
2. Vessel and lesion dimensions
3. Confirmation of atherosclerotic plaque
4. Adequacy of stent deployment
Image Features of IVUS
• The relative echolucency of media compared with
intima and adventitia gives rise to a three-layered
appearance (bright-dark-bright).
• The basic image features
are listed here from
the center outward:
Dead zone
Catheter artifact
Lumen
Inner layer
Middle
Outer echogenic layer
Cross-sectional format of a typical IVUS image .
The bright-dark-bright, three- layered appearance is seen
in the image with corresponding anatomy.
Dimensional Measurements
• Lumen and vessel diameters. Minimal, maximal,
and mean diameters may be obtained.
• Percentage diameter or area stenosis is the lumen
diameter or area within the lesion segment divided
by the lumen diameter or area within the reference
segment. This is similar to the measurements made
by angiography.
• Total vessel area. The vessel cross-
sectional area is the area confined
within the external elastic lamina or
the media-adventitia interface.
• Lumen area is confined within the
lumen-intima interface.
• Wall area (intima and media)
equals total area minus lumen area.
• In abnormal vessels, this is the
plaque area (also called plaque plus
media area).
• Percentage plaque area (also called plaque
burden or percentage cross-sectional narrowing)
• Percentage plaque area = (total area - lumen
area/total area) × 100.
• Indices of Eccentricity. A lesion eccentricity index
(LECC) is calculated by lumen dimensions: LECC =
maximum diameter/minimum diameter.
IVUS Plaque Morphology
• Soft Plaque: echogenicity less than
the surrounding adventitia
• Fibrous Plaque: intermediate
echogenicity between those of soft
plaques and highly echogenic
calcified plaques
• Calcified Plaque: echogenicity
higher than that of the adventitia
with acoustic shadowing
• Mixed Plaque: more than one
subtype contained within the
plaque
Additional Plaque Features
• Plaque Location
• Intimal Flap or Dissection
• Thrombus
• Aneurysm
• Side Branches
Vulnerable Plaque
• Atherosclerotic Lesions at High Risk for Rupture.
IVUS characteristics of vulnerable plaque
Applications of IVUS
Diagnostic Applications
• Ambiguous Angiograms and Indeterminate Coronary
Lesions
• Evaluation of the Left Main Coronary Artery
• Evaluation of Transplant Vasculopathy
Interventional Applications
• Vessel Sizing
• IVUS Imaging in Coronary Stenting
• Strut Malapposition
• Management of Stent Restenosis
• Assessment of Complications After Intervention
Thank you

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Intravascular Ultrasound (IVUS)

  • 1. Intravascular ultrasound (IVUS) ______________________________________________________ Dr. Sayeedur Rahman Khan Rumi dr.rumibd@gmail.com MD (Cardiology) Final Part Student National Heart Foundation Hospital and Research Institute
  • 2. Introduction • Intravascular ultrasound (IVUS) catheters use reflected sound waves to visualize the arterial wall in a two-dimensional, tomographic format, analogous to a histologic cross section. • This offers the opportunity to gather diagnostic information about the process of atherosclerosis and to directly observe the effects of various interventions on the plaque and arterial wall.
  • 3. Imaging Systems Two types of IVUS systems exist, both utilizing 20- to 40-MHz silicon piezoelectric crystals: A. Mechanical system that relies on a rotating internal cable, and B. Solid-state system externally mounted on a catheter and controlled electronically
  • 4. Diagrams of the two basic imaging catheter designs, solid state (A) and mechanical (B)
  • 5. • With the mechanical systems, the imaging core rotates via a flexible drive shaft to sweep the transducer continuously through a 360-degree arc in the vessel. • The solid-state catheter has 64 ultrasound transducers arranged circumferentially around the catheter tip and sequentially activated to produce a 360-degree image.
  • 6. • Both IVUS catheters range in size from 3.2 F to 3.5 F and have a tapered tip and shaft. • They are designed to fit through a 6 F guide catheter. • The IVUS catheter connects to a console, which displays and records the images digitally. • Images from both systems are displayed in a tomographic, real-time video format. • Currently, IVUS has a resolution of approximately 100 to 150 μm.
  • 7.
  • 8. Common clinical applications for IVUS 1. Assessment of lesion calcium 2. Vessel and lesion dimensions 3. Confirmation of atherosclerotic plaque 4. Adequacy of stent deployment
  • 9. Image Features of IVUS • The relative echolucency of media compared with intima and adventitia gives rise to a three-layered appearance (bright-dark-bright). • The basic image features are listed here from the center outward: Dead zone Catheter artifact Lumen Inner layer Middle Outer echogenic layer
  • 10. Cross-sectional format of a typical IVUS image . The bright-dark-bright, three- layered appearance is seen in the image with corresponding anatomy.
  • 11. Dimensional Measurements • Lumen and vessel diameters. Minimal, maximal, and mean diameters may be obtained. • Percentage diameter or area stenosis is the lumen diameter or area within the lesion segment divided by the lumen diameter or area within the reference segment. This is similar to the measurements made by angiography.
  • 12. • Total vessel area. The vessel cross- sectional area is the area confined within the external elastic lamina or the media-adventitia interface. • Lumen area is confined within the lumen-intima interface.
  • 13. • Wall area (intima and media) equals total area minus lumen area. • In abnormal vessels, this is the plaque area (also called plaque plus media area).
  • 14. • Percentage plaque area (also called plaque burden or percentage cross-sectional narrowing) • Percentage plaque area = (total area - lumen area/total area) × 100. • Indices of Eccentricity. A lesion eccentricity index (LECC) is calculated by lumen dimensions: LECC = maximum diameter/minimum diameter.
  • 15. IVUS Plaque Morphology • Soft Plaque: echogenicity less than the surrounding adventitia • Fibrous Plaque: intermediate echogenicity between those of soft plaques and highly echogenic calcified plaques
  • 16. • Calcified Plaque: echogenicity higher than that of the adventitia with acoustic shadowing • Mixed Plaque: more than one subtype contained within the plaque
  • 17. Additional Plaque Features • Plaque Location • Intimal Flap or Dissection • Thrombus • Aneurysm • Side Branches
  • 18. Vulnerable Plaque • Atherosclerotic Lesions at High Risk for Rupture. IVUS characteristics of vulnerable plaque
  • 19. Applications of IVUS Diagnostic Applications • Ambiguous Angiograms and Indeterminate Coronary Lesions • Evaluation of the Left Main Coronary Artery • Evaluation of Transplant Vasculopathy Interventional Applications • Vessel Sizing • IVUS Imaging in Coronary Stenting • Strut Malapposition • Management of Stent Restenosis • Assessment of Complications After Intervention