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drug of abuse.pptx
This document discusses drugs of abuse, including their effects and signs of abuse. It describes various classes of drugs like stimulants, depressants, and hallucinogens. Stimulants like cocaine and amphetamines cause alertness while depressants like alcohol and barbiturates are sedating. Hallucinogens result in effects like blurred vision and anxiety. Long term drug abuse can lead to signs like mood swings, altered work efficiency, and poor physical hygiene. Drug screening tests detect illegal substances in bodily fluids and are often confirmed with techniques like GC/MS or LC-MS/MS.
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drug of abuse.pptx
- 1. Drug of Abuse Toxicology& Forensic Serology 1 Dr. Aamir Ali Khan Assistant Professor
- 2. Drug ofAbuse 7/6/2021 Toxicology& Forensic Serology 1 • The habitual use of drugs • Not needed for therapeutic purposes • Solely to alter one's mood • Affect of state of consciousness, or to affect a body function unnecessarily • Continuous use result in physical & medical dependence e.g.cocaine,heroin ,alcohol
- 3. Drug Dependence Toxicology &Forensic Serology 3 • Physical Dependence: the body need drugs to feel normal & function properly • Body physiology altered & worked satisfactorily if large doses of drugs available • The withdrawal symptoms (e.g pain) proof of physical dependence
- 4. • Psychological dependence:There is carving for repeated or compulsive use of drugs to satisfy emotion or personality needs • If discontinued result in absence of pleasure but no physical pain 7/6/2021 Toxicology & Forensic Serology 4
- 5. • Psychotropic Drugs:these are drugs that could alter mental function by their action, it include stimulants,depressants,narcotics and hallucinogen. 7/6/2021 Toxicology & Forensic Serology 5
- 6. Drug ofAbuse Hypnotics: these aredrugs which produce sleep,e.g. barbiturates Narcotics: these are drugs which relieve pain & produce Sleep e.g. opium, morphine Sedatives: these are drugs which produce a calming effect on central nervous system 7/6/2021 Toxicology & Forensic Serology 6
- 7. Drug ofAbuse Stimulants: drugs whichproduce wakefulness, alertness by acting on CNS e.g.amphetamine Hallucinogen: these are drugs which produce bizarre effects on mind such as distortion of time, space,sound, color etc e.g. Phencyclidine Street Drugs: these are drugs obtained not from pharmacist but surreptitious sources, it is usually adulterated drugs 7/6/2021 Toxicology & Forensic Serology 7
- 8. Effect of Stimulants 7/6/2021Toxicology & Forensic Serology 8 • Alertness • Increased energy • Restlessness • Wakeful ness • Euphoria • Reduced appetite • Talkative • Increased BP,heart rate and breathing
- 9. Cocaine Amphetamine Nicotine 7/6/2021 Toxicology &Forensic Serology 9 Stimulants Street name : Crack, Snow , Star dust, Charlie, Nose candy Street name : Black beauties , co-pilots ,crystal meth , heart
- 10. Effect of Depressants 1 0 7/6/2021Toxicology & Forensic Serology • Depressant is a substance that reduces the normal body activity,function or an instinctive desire such as appetite for food.It is also known as“downers” – Highly addictive – Sedating – Dizziness – Anxiety /hypnosis
- 11. Alcohol Barbiturate s Cannabis Opioid Depressants Street name: Benzos, Downers, Goofballs Street name : Dope , Painkillers , Oxy 1 1 7/6/2021 Toxicology & Forensic Serology
- 12. Effects of Hallucinogen 1 2 7/6/2021Toxicology & Forensic Serology • Blurred vision & loss of coordination • Increased breathing,heart rate & BP • Anxiety,agitation • Increased body temperature,feeling numbness • euophoria
- 13. Marijuana PCP (phencyclidine) LSD Hallucinogen Weed &pot, Mary jane, ganga, Street name : Angel dust, love boat, wack,rocket fuel, peace pills Street name : Street name : Acid Battery acid Blotter Boomers hash,herb 1 3 7/6/2021 Toxicology & Forensic Serology
- 14. Common Sign OfDrugAbuse Drug Dependent Mood Swing 1 4 7/6/2021 Toxicology & Forensic Serology This Photo by Unknown Author is licensed under CC BY-SA- NC
- 15. Common Sign OfDrugAbuse This Photo by Unknown Author is licensed under CC BY-SA- NC Altered work efficiency Toxicology & Forensic Serology 1 5 7/6/2021
- 16. Common Sign OfDrugAbuse Injection marks on addict body 1 6 7/6/2021 Toxicology & Forensic Serology
- 17. Common Sign OfDrugAbuse Stealing items to support Drug habit This Photo by Unknown Author is licensed und T er oC xC ic B o Y l- o N g D y & Forensic 1 7 7/6/2021 Serology
- 18. Common Sign OfDrugAbuse This Photo by Unknown Author is licensed under CC BY-NC- ND Poor Physical Hygiene Toxicology & Forensic Serology 1 8 7/6/2021
- 19. Drug ofAbuse Screening 1 9 7/6/2021Toxicology & Forensic Serology • Detection of one or more illegal substance in urine, blood,saliva,sweat or organ of deceased • Testing detects substance normally not found in body • Chromatographic technique can be use for screening of multiple drugs (qualitative analysis) • Cut off value use for quantitative screening
- 20. Drug ofAbuse Screening 2 0 7/6/2021Toxicology & Forensic Serology • Positive qualitative screening test considered presumptive • Must be confirmed with more specific & sensitive method • Gas chromatography/mass spectrometry (GC/MS) or liquid chromatography-tandem mass spectrometry (LC-MS/MS) recommended for medicolegal cases
- 21. Commonly screened drugclasses 7/6/2021 Toxicology & Forensic Serology 1 2 https://labtestsonline.org/tests/drug-abuse-testing dated: 4/7/2021
- 22. Referenc e • Text bookof Medical Jurisprudence,Forensic medicine andToxicology, BV Subrahmanym Seventh editio • https://labtestsonline.org/tests/drug-abuse-testing 7/6/2021 Toxicology & Forensic Serology 2