1) The document discusses disturbances of body schema and spatial relationships that can occur due to lesions in the parietal lobes. It defines concepts like body schema, autotopagnosia, spatial disorientation, and hemispatial neglect.
2) Tests for evaluating these conditions are described, including those for anosognosia, autotopagnosia, and hemispatial neglect. Common sites of lesions that cause different symptoms are also outlined.
3) Additional syndromes discussed include constructional apraxia, dressing apraxia, loss of topographical memory, allesthesia, and hemi somatognosia. The key features and evaluations of these conditions are summarized.
The neurophysiology of posture and movement. Its postural framework and CNS structures involved in the control of postural movement and postural reflexes. The influence of muscle tone on posture.
This presentation is primarily based on an article Titled "Rehabilitation of Unilateral Spatial Neglect: New Insights from Magnetic Resonance Perfusion Imaging" by Argye E Hillis., Arch Phys Med Rehabil 2006;87(12 Suppl 2):S43-9.
Aim of this presenattaion was to give an insight to my students about Rehabilitation of Unilateral Spatial neglect
The neurophysiology of posture and movement. Its postural framework and CNS structures involved in the control of postural movement and postural reflexes. The influence of muscle tone on posture.
This presentation is primarily based on an article Titled "Rehabilitation of Unilateral Spatial Neglect: New Insights from Magnetic Resonance Perfusion Imaging" by Argye E Hillis., Arch Phys Med Rehabil 2006;87(12 Suppl 2):S43-9.
Aim of this presenattaion was to give an insight to my students about Rehabilitation of Unilateral Spatial neglect
It is a technique developed by Janet H Carr and Roberta B Shepherd which provides physiotherapists and occupational therapists with an approach to stroke rehabilitation that is clear, relevant, and effective, building on the research-based model created by the authors
این ارائه در کارگاه تخصصی تقلید و آپراکسی سرنخ هایی برای مداخلات مبتنی بر شواهد توسط دکتر هاشم فرهنگ دوست تدریس شده است.
برای مطالعه مطالب بیشتر در این زمینه به وب سایت فروردین مراجعه کنید.
www.farvardin-group.com
Anomalous Innervations in (EMG/NCS) by MurtazaMurtaza Syed
Anomalous Innervation.
These are the sort of normal variants which can be found in any normal subject or can concomitantly be found or superimposed in pathological cases. Identifying these anomalies helps out interpreting and making correct diagnosis and to avoid any misinterpretation.
This presentation is detail about Volta therapy which is commonly used in paediatric neurological conditions and also for adults. this presentation explains what are the various techniques, methods of application of Volta therapy, indications, contraindications, etc.
Spina Bifida: Physiotherapy in the management of meningomyeloceleAyobami Ayodele
Spina bifida is a treatable spinal cord malformation that occurs in varying degrees of severity. Meningomyelocele is associated with abnormal development of the cranial neural tube, which results in several characteristic CNS anomalies. About 90% of babies born with Spina Bifida now live to be adults, about 80% have normal intelligence and about 75% play sports and do other fun activities. Most do well in school, and many play in sports.
It is a technique developed by Janet H Carr and Roberta B Shepherd which provides physiotherapists and occupational therapists with an approach to stroke rehabilitation that is clear, relevant, and effective, building on the research-based model created by the authors
این ارائه در کارگاه تخصصی تقلید و آپراکسی سرنخ هایی برای مداخلات مبتنی بر شواهد توسط دکتر هاشم فرهنگ دوست تدریس شده است.
برای مطالعه مطالب بیشتر در این زمینه به وب سایت فروردین مراجعه کنید.
www.farvardin-group.com
Anomalous Innervations in (EMG/NCS) by MurtazaMurtaza Syed
Anomalous Innervation.
These are the sort of normal variants which can be found in any normal subject or can concomitantly be found or superimposed in pathological cases. Identifying these anomalies helps out interpreting and making correct diagnosis and to avoid any misinterpretation.
This presentation is detail about Volta therapy which is commonly used in paediatric neurological conditions and also for adults. this presentation explains what are the various techniques, methods of application of Volta therapy, indications, contraindications, etc.
Spina Bifida: Physiotherapy in the management of meningomyeloceleAyobami Ayodele
Spina bifida is a treatable spinal cord malformation that occurs in varying degrees of severity. Meningomyelocele is associated with abnormal development of the cranial neural tube, which results in several characteristic CNS anomalies. About 90% of babies born with Spina Bifida now live to be adults, about 80% have normal intelligence and about 75% play sports and do other fun activities. Most do well in school, and many play in sports.
CONCEPT OF NODOPATHIES AND PARANODOPATHIES.pptxNeurologyKota
emergence of autoimmune neuropathies and role of nodal and paranodal regions in their pathophysiology.
Peripheral neuropathies are traditionally categorized into demyelinating or axonal.
dysfunction at nodal/paranodal region key for better understanding of patients with immune mediated neuropathies.
antibodies targeting node and paranode of myelinated nerves have been increasingly detected in patients with immune mediated neuropathies.
have clinical phenotype similar common inflammatory neuropathies like Guillain Barre syndrome and chronic inflammatory demyelinating polyradiculoneuropathy
they respond poorly to conventional first line immunotherapies like IVIG
This presentation briefs out the approach of dementia assessment in line with consideration of recent advances. Now the pattern of assessment has evolved towards examining each individual domain rather than lobar assessment.
This presentation contains information about Dementia in Young onset. Also it describes the etiologies, clinical feature of common YOD & their management.
Entrapment Syndromes of Lower Limb.pptxNeurologyKota
This presentation contains information about the various Entrapment syndromes of Lower limb in descending order of topography. It also contains information about etiology, clinical features and management of each of these entrapment syndromes with special emphasis on electrodiagnostic confirmation.
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
Health Education on prevention of hypertensionRadhika kulvi
Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
ICH Guidelines for Pharmacovigilance.pdfNEHA GUPTA
The "ICH Guidelines for Pharmacovigilance" PDF provides a comprehensive overview of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines related to pharmacovigilance. These guidelines aim to ensure that drugs are safe and effective for patients by monitoring and assessing adverse effects, ensuring proper reporting systems, and improving risk management practices. The document is essential for professionals in the pharmaceutical industry, regulatory authorities, and healthcare providers, offering detailed procedures and standards for pharmacovigilance activities to enhance drug safety and protect public health.
The Importance of Community Nursing Care.pdfAD Healthcare
NDIS and Community 24/7 Nursing Care is a specific type of support that may be provided under the NDIS for individuals with complex medical needs who require ongoing nursing care in a community setting, such as their home or a supported accommodation facility.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
distribution of body schema and spatial relationship
1. Disturbances of “Body Schema”
and Spatial Relationships.
DR.PRAMOD MEENA
SR NEUROLOGY
GMC,KOTA
2. • Head and Holmes discussed two schemas :
1. One body schema for the registration of posture or movement and
2. Another body schema for the localization of stimulated locations on
the body surface.
• "Body schema" became the term used for the "organized models of
ourselves".
• The term and definition first suggested by Head and Holmes
DEFINITION:
3. • The body schema represents both position and configuration of the
body as a 3-dimensional object in space.
• A combination of sensory information, primarily tactile and visual,
contributes to the representation of the limbs in space.
• This integration allows for stimuli to be localized in external space
with respect to the body.
• Body schema also plays an important role in the integration and use
of tools by humans.
• Both parietal lobe responsible for body schema and spatial
relationship
5. ANOSOGNOSIA
• The term anosognosia originally referred to a specific unawareness of
paralysis following stroke (Babinski in 1914).
• Anosognosia occurred in 2 phase
1. Hyperacute phase (3 days post stroke) was related to damage in the
anterior insula and anterior subcortical structures.
2. Later phase (still present one week later) was associated with
additional lesions in parietal, frontal, and temporal structures.
6. Questionnaire : for Anosognosia
In Hemiplegic patient
1.Do you have weakness anywhere?
2.Is your arm causing you any problems?
3. Does it feel normal?
4. Can you use it as well as you used to?
5.Are you fearful about losing your ability to use your
arm?
7. Cont..
6.Is the sensation in your arm normal?
7.The doctors tell me that there is some paralysis
of your arm. Do you agree?
8.Left arm is lifted and dropped in left hemispace.
“It seems there is some weakness. Do you agree?”
9.Left arm is lifted and dropped in right hemispace.
“It seems there is some weakness. Do you agree?”
10.Take your right arm, and use it to lift your left
arm. Is there any weakness of your left arm?”
Feinberg, Roane, and Ali (2000).
Each item is scored as
0 -(shows awareness),
0.5- (partial awareness), or
1 -(complete unawareness).
8.
9. AUTOTOPAGNOSIA
• Autotopagnosia is a form of agnosia, characterized by
an inability to localize and orient different parts of the body.
• lesion found in the parietal lobe of the left hemisphere of the brain.
• No medications or pharmaceutical remedies have been approved by
the U.S. FDA to treat or cure autotopagnosia.
10. Test: for self body part localization
TEST 1 Specifications Description
A Verbal command: point to self Examiner names a body part, and the subject instructed
to point to that part on themselves
B Verbal command: point to examiner Examiner names a body part, and the subject instructed
to point to that part on the examiner
C Verbal cue: point to self Examiner point to body part on himself, and su
bject are required to point to the homologus part on
themselves.
D Verbal cue: point to examiner Examiner point to body part on subject,and they are
required to point to the homologus part on the examiner.
E Blindfold post-visual cue:point to self Same as study 1c except subjects are blindfolded after
examiner point to himself, prior to response execution.
12. SPATIAL DISORIENTATION
• Spatial Disorientation is the
inability to maintain body orientation and
posture in relation to the surrounding environment (physical space) at
rest and during motion.
• Spatial orientation involves visual, auditory, vestibular, &
proprioceptive sensory information & lesion at right parietal or right
prefrontal cortex.
13. CONT…
• Mainly seen in pilots and divers
• Unfamiliar three-dimensional environment of flight to the human
body.
• creating sensory conflicts.
• illusions that make spatial orientation difficult and sometimes
impossible to achieve.
15. HEMISPATIAL NEGLECT
• Hemispatial neglect is
Defined by the inability of a person to process and
perceive stimuli towards the contralesional side of the body or
environment
• Stimulus-visual, auditory, proprioceptive, and olfactory.
• Neglect occurred when damage to the temporo-parietal junction &
posterior parietal cortex.
18. 1. 3. 4.
Letter search
2.Line
cancellation
Clock drawing
Line bisection
19.
20.
21. Mayer-Gross closing-in phenomenon
• Pt. place their drawings close to the model or superimpose the copy
on the model.
• Seen in Patients with diffuse cortical damage.
• Alzheimer disease
22. • Inability to draw or construct 2 or 3D figures or shapes
in presence of normal strength, coordination, sensation ,
comprehension.
• More common and severe with
right non dominant parietal lesion than left.
CONSTRUCTIONAL APRAXIA
23. Tests
• Reproduction drawings
1. both 2D and 3D drawings as vertical diamond,
2. 2D cross,
3. 3D block,
4. 3D pipe,
5. triangle within triangle are used.
Scoring done from poor (0) to excellent (3)
24. Cont..
scoring interpretation
Poor(0) Non recognizable, gross
distortion
Fair(1) Moderately distorted or rotated
2D
Good(2) Minimal distortion
Excellent(3) Perfect or near perfect
Rating 0 = 100% probability of brain damage
Rating 1=80% probability of brain damage
Vertical diamond
26. • Unable to properly cloth themselves.
• Most often leaves left side partly undressed.
• MC with Right non-dominant parietal lesions.
• Associated with impaired tactile and visuo
spatial coordination Considered as part of
neglect syndrome.
DRESSING APRAXIA
27.
28. Definition:
Inability to find way to familiar environments
Difficulty in localize places on maps
And find his way to new environment
LOSS OF TOPOGRAPHICAL MEMORY
29. Evaluation
History obtained from family
1.Does patient lost at neighborhood, or home?
2.Has pt. lost travelling less frequent location?
3.Does pt. have difficulty orienting new
environment?
30. CONT…
Localizing places on maps
Ask pt. to draw map of India, if pt. can’t draw then
doctor should draw map.
Ask pt. to locate cities on map eg. Delhi, Mumbai, Calcutta.
1.Are cities located in appropriate states?
2.Are cities located on one half of map(either east or west)?
Ability to orient self in hospital environment
Ask nurses staff regarding pt. capacity to find their bed, ward & bathroom.
31. ALLESTHESIA
• In which sensation is felt at a different point on the body from that
stimulated.
• Most commonly patients with allesthesia incorrectly identify left-
sided stimuli as coming from the right side.
• When stimulated on the side contralateral to a hemispheral lesion(rt
parietal), in which they misplace the location of the stimulus to the
normal side.
• Patients with allokinesia respond with the wrong limb or move in the
wrong direction.
32. HEMISOMATOGNOSIA
• It is a unilateral misperception of one’s own body.
• Lesion in right parietal hemisphere.
• Types -
1. conscious -the patient feels like a hemiampute.
2. unconscious -the patient behaves as a hemiampute.
33. Cont..
1. The conscious form is
transient, subcortical origin, unimodal, non-lateralizing & seen in
paroxysmal disease, e.g. migraine or seizure disorder.
2.The unconscious form is
permanent, non-dominant parietal origin,
multimodal (i.e., associated with neglect, anosognosia,
astereognosis, and constructional apraxia), (e.g., stroke).
34. ASYMBOLIA FOR PAIN
• Pt. recognize pain but lack appropriate motor and emotional
responses to painful stimuli applied anywhere on the body surface
& appear insensitive to visual threats and to verbal menaces.
• Lesion present at left supramarginal gyrus infarction and additional
damage involving the angular gyrus, the second frontal and first
temporal convolutions, the external capsule, and the insular cortex
35.
36. Cont..
• Superficial pain
assessed through pinprick and thermal stimuli applied in a single,
repetitive, or prolonged way over the face, neck, trunk, limbs, and perineal
region.
• Deep pain
tested by heavy pressure to pretibial, sternal, and supraorbital
regions; passive hyperextension of fingers and toes; squeezing of calf
muscles and Achilles tendons; and pinching of soft tissues on all four limbs.
• Motor responses -withdrawal and grimacing.
• emotional behavior and autonomic reactions to noxious stimuli.
• AP commonly associated with transient hemiparesis, sensory loss, visual
field defects, neglect, body-schema disorders, aphasia, and apraxia.
37. FINGER AGNOSIA
• Inability to recognize, name, and point to individual fingers on
self and others
• Pt. have lesion in dominant hemisphere
• Lt handed pts. may have finger agnosia with lesions of either
hemisphere.
38. TESTS
1.Non verbal finger recognition:
Pt. eyes closed touch pt finger, then ask pt to point same finger on
examiner hand Identification of named fingers on examiner’s hand &
examiner’s hand placed in various positions.
2.Verbal identification
naming of finger on self and examiner: hand placed in various
positions, ask pt “what is the name of this finger”
39. RIGHT-LEFT DISORIENTATION
Inability to distinguish right from left on self or environment.
More common with left hemisphere lesion Normal population
9%males, 17% females.
Tests
• Identification on self(show me your right foot),
• Crossed commands on self(With your right hand touch your left shoulder)
• Identification on examiner(point to my left elbow)
• Crossed command on examiner(with your right hand point to my left eye)
40. GERSTMANN SYNDROME
It is tetrad
i. FINGER AGNOSIA,
ii. RIGHT-LEFT DISORIENTATION,
iii. AGRAPHIA
iv. ACALCULIA
lesions in the
angular & supramarginal gyri of the dominant hemisphere
43. ALEXIA
Definition Inability to read written language
Types:
1.ALEXIA WITH AGRAPHIA or CENTRAL ALEXIA
lesion in angular gyrus.
Inability of reading and writing & these patients usually also have
acalculia, finger agnosia, right-left disorientation and difficulty with
spelling words and understanding spelled-out words
44. Dejerine described it in 1892
damage of the corpus callosum fibers connecting the parieto-occipital regions of
the two hemispheres.
It represents the first described inter-hemispheric disconnection syndrome.
Patients cannot read but are able to write on dictation.
Alexia without agraphia results from damage to the pathways conveying visual
input from both hemispheres to the dominant angular gyrus. It may also rarely
occur with infarction of the left lateral geniculate body and the splenium of the
corpus callosum.
2.ALEXIA WITHOUT AGRAPHIA (PURE ALEXIA OR PURE WORD BLINDNESS)
45.
46. APRAXIA
• Inability to carry out a commanded task despite the retention of
motor and sensory function.
• Sensory areas 5 & 7 in dominant parietal lobe, supplementary and
premotor cortex of both cerebral hemispheres and their integral
connection.
• Types
1.Ideomotor apraxia(how to do)
2.Ideational apraxia (what to do)
47. IDEOMOTOR APRAXIA
• Failure to perform previously learned motor acts accurately.
• Results from left hemisphere lesion
TESTS
carrying out motor acts to command:
1.Buccofacial-blow out a match, protrude tongue, drink through a
straw
2.limb-use a toothbrush, flip a coin, hammer a nail, comb hair,
48. IDEATIONAL APRAXIA
• Able to carry out individual components of a complex motor act but
can not perform the entire sequence properly leading to a goal.
• Results from left hemisphere lesion( temporo-parietal)
TESTS
• Opening tooth paste and placing toothpaste on brush.
• How to drive a car
• How to mail a letter.
49. CONCLUSION
• Parietal lobes are important to the processing of sensory information,
understanding spatial orientation and body awareness.
• The parietal lobes process the information and help us to identify
objects by touch & work in concert with other areas of the brain,such
as the motor cortex and visual cortex to perform certain tasks.
• Even after assessment of clinical symptom and signs it is difficult to
ascertain all signs to particular area of the parietal lobe.
50. REFRENCES
• Paul M. Jenkinson , Catherine Preston & Simon J. Ellis (2011)
Unawareness after stroke: A review and practical guide to understanding,
assessing, and managing anosognosia for hemiplegia, Journal of Clinical
and Experimental Neuropsychology, 33:10, 1079-1093,
• " Mosby's Medical Dictionary, 2009. Volume 8. Last updated 2009.
Accessed February 22, 2011
• Bradely′s Neurology in clinical practice, 8th edition
• Brazis 7th edition neurology
• Up to date
Editor's Notes
anosognosia is more frequent following righthemisphere brain damage, suggesting that the condition is a right-hemisphere syndrome. This has resulted in the term anosognosia being used to denote any form of unawareness or lack of insight.
Cotard syndrome or Cotard delusion comprises any one of a series of delusions ranging from the unshakable belief that one has lost organs, blood, or body parts to believing that one has lost one’s soul, is dead, or does not exist.
This condition especially seen in aircraft pilots and underwater divers.
Types of hemispatial neglect are broadly divided into disorders of input and disorders of output. The neglect of input, or "inattention", includes ignoring contralesional sights, sounds, smells, or tactile stimuli. Surprisingly, this inattention can even apply to imagined stimuli. In what's termed "representational neglect", patients may ignore the left side of memories, dreams, and hallucinations.
Output neglect includes motor and pre-motor deficits. A patient with motor neglect does not use a contralesional limb despite the neuromuscular ability to do so. One with pre-motor neglect, or directional hypokinesia, can move unaffected limbs ably in ipsilateral space but have difficulty directing them into contralesional space. Thus a patient with pre-motor neglect may struggle to grasp an object on the left side even when using the unaffected right arm
In this form, patients have no concern about one-half of the body and tend to leave the arm dangling, to not cover half the body, and to not shave half the face.