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P R E S E N T E D B Y :
D R . P A L L A V I P A T H A N I A
DIABETES MELLITUS
 Diabetes mellitus (DM) is a group of diseases
characterized by high levels of blood glucose
resulting from defects in insulin production, insulin
action, or both.
 The term diabetes mellitus describes a metabolic
disorder of multiple aetiology characterized by chronic
hyperglycaemia with disturbances of carbohydrate, fat
and protein metabolism resulting from defects in
insulin secretion, insulin action, or both.
What is diabetes?
RISK FACTORS
Who are
prone ...?
Classification / Etiology of diabetes mellitus
1. Type 1 diabetes
2. Type 2 diabetes
3. Secondary diabetes
4. Gestational diabetes
Type 1 diabetes
• Occur at any age, but usually <30
years
• Usually thin at diagnosis
• Can be due to genetic,
immunologic or environmental
factors
• Can have islet cell antibodies
• No endogenous insulin , so
require exogenous insulin
• Diabetic ketoacidosis prone
Type 2 Diabetes
• Onset at age , usually >30
years
• Usually obese at diagnosis
• Can be due to hereditary or
environmental factors
• No islet cell antibodies
• Decreased insulin production
or decreased sensitivity to
insulin
• Oral anti-diabetic agents may
improve blood glucose levels
• Diabetic keto-acidosis is rare
Gestational Diabetes
• Onset usually in 2nd or 3rd
trimester
• Placental hormones
reduces action of insulin
• Treated with diet or insulin
PATHOPHYSIOLOGY
SIGN AND SYMPTOMS
Diagnostic Criteria
• Polyuria, Polyphagia , Polydipsia plus plasma
glucose concentrations > 200 mg/dl
• Fasting plasma glucose concentrations > 126
mg/dl
• 2- hour post-parandial plasma glucose
concentration > 200 mg/dl
•Glycosylated hemoglobin
Fasting Plasma Glucose
Diagnostic range of blood sugar (plasma glucose)
Normal
glucose
tolerance
Impaired
glucose
tolerance
Diabetes
mellitus
Fasting plasma glucose
(mg/dL)
<110 110-126 >126
Between 0-120 min (mg/dL) <200 <200 200 at
least
once
2 hours after glucose load
(mg/dL)
<140 >140, but
<200
>200
Urinalysis
Glycosuria
Ketone bodies
Management of
Diabetes Mellitus
Management
Nutrition
Exercise
MonitoringDrugs
Education
 The major components of the treatment of diabetes
are:
Management of DM
• Diet and
ExerciseA
• Oral hypoglycaemic
therapyB
• Insulin TherapyC
Dietary Considerations
• BMI
• Activity level
• Age / Sex
• Present food habits
• Economic status
• Complications in Diabetes
• Treatment of Diabetes
 Diet is a basic part of management in every case.
 Dietary treatment should aim at:
◦ ensuring weight control
◦ providing nutritional requirements
◦ allowing good glycaemia control with blood glucose levels as
close to normal as possible
A. Diet
The following principles are recommended as
dietary guidelines for people with diabetes:
 Dietary fat should provide 25-35% of total intake of
calories but saturated fat intake should not exceed 10% of
total energy.
 Cholesterol consumption should be restricted and limited
to 300 mg or less daily.
 Protein intake can range between 10-15% total energy (0.8-
1 g/kg of desirable body weight).
 Excessive salt intake is to be avoided. It should be
particularly restricted in people with hypertension and
those with nephropathy.
A. Diet (cont.)
Exercise
• Provides physical fitness
• Carbohydrate metabolism
• Weight & insulin sensitivity
• Risk factors for cardio-
vascular disease
• Blood pressure & Cardiac
work
 Physical activity promotes weight reduction and
improves insulin sensitivity, thus lowering blood
glucose levels.
Exercise
Considerations during exercise
• Use proper footwear during
exercise
• Avoid exercise in extremes of
temperature
• Inspect feet daily
• Avoid exercise in periods of
poor metabolic control
• Do not exercise empty or full
stomach
Monitoring
A – A1C Levels {estimated average
BS level}
B – Blood pressure
C – Cholesterol
D – Diabetic education
E – Eye Examination
F – Foot Examination
G – Blood Glucose Examination
H – Health
I – Indications & Referral
Drugs
Oral Hypoglycemic
Agents Insulin
 There are currently four classes of oral anti-diabetic
agents:
i. Biguanides
ii. Sulphonylureas
iii. Non-sulphonylureas
iv. α-glucosidase inhibitors
v. Thiazolidinediones (TZDs)
B. Oral Anti-Diabetic Agents
Oral Hypoglycaemic Medications
C. Insulin THERAPY
Used in treatment of –
• Type 1 Diabetes
• Acute Conditions of Type 2
Diabetes
35
Delivery Methods
 Insulin Syringe
 Insulin Pen
 Insulin Pump
 Jet Injector
Insulin Injection sites
Nursing Management
Nursing Assessment
Nursing Diagnosis
1) Imbalanced Nutrition Less Than Body Requirements R/T reduction of
carbohydrate metabolism due to insulin deficiency, inadequate intake due to nausea
and vomiting.
2) Fluid Volume Deficit related to osmotic diuresis from hyperglycemia, polyuria,
decreased fluid intake.
3) Impaired Skin Integrity related to decreased sensory sensation, impaired
circulation, decreased activity / mobilization, lack of knowledge of skin care.
4) Activity Intolerance related to weakness due to decreased energy production.
5) High risk of injury associated with decreased sensation sensory (visual),
weakness, and hypoglycemia.
6) Anxiety related to a lack of knowledge (diabetes management), the ability to
remember the less, diagnosis or treatment of a new way, cognitive limitations.
7) Risk for ineffective management of therapeutic rules at home due to a lack of
knowledge about the condition of the therapeutic management, inadequate support
systems.
Nursing diagnosis ……(Contd.)
Altered nutrition : less than
body requirements
•Abnormal glucose
metabolism
•Depletion of fat stores,
cellular proteins
•Decreased oral intake –
dislike of prescribed diet,
anorexia gastric fullness
Nursing diagnosis ……(Contd.)
Altered fluid –volume deficit
•Osmotic diuresis
•Vomiting
•Diarrhea
•Diabetic Keto-acidosis
Nursing diagnosis ……(Contd.)
Impaired skin integrity
•Abnormal pressure distribution due to peripheral
neuropathy
•Delayed wound healing
Nursing diagnosis ……(Contd.)
Altered systemic tissue
perfusion
•Vascular abnormalities
•Hypovolemia
•Orthostatic hypotension
Nursing Diagnosis
Anxiety
•Unfamiliar environment
•Lack of understanding of
diagnosis & management
•Possible changes in life-
style & roles
Education
• Diabetes Mellitus
• Approaches Of Management
• Dietary Requirements
• Exercise Regimen
• Oral Hypoglycemic Drugs
• Insulin therapy
• Complications
• Foot care
• Adherence to treatment & Follow-up
 Patients should be educated to practice self-care. This allows the
patient to assume responsibility and control of his / her own
diabetes management. Self-care should include:
◦ Blood glucose monitoring
◦ Body weight monitoring
◦ Foot-care
◦ Personal hygiene
◦ Healthy lifestyle/diet or physical activity
◦ Identify targets for control
◦ Stopping smoking
Self-Care
“Of course too
much is bad for
you”

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Diabetes mellitus

  • 1. P R E S E N T E D B Y : D R . P A L L A V I P A T H A N I A DIABETES MELLITUS
  • 2.  Diabetes mellitus (DM) is a group of diseases characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both.  The term diabetes mellitus describes a metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. What is diabetes?
  • 3.
  • 6. Classification / Etiology of diabetes mellitus 1. Type 1 diabetes 2. Type 2 diabetes 3. Secondary diabetes 4. Gestational diabetes
  • 7. Type 1 diabetes • Occur at any age, but usually <30 years • Usually thin at diagnosis • Can be due to genetic, immunologic or environmental factors • Can have islet cell antibodies • No endogenous insulin , so require exogenous insulin • Diabetic ketoacidosis prone
  • 8. Type 2 Diabetes • Onset at age , usually >30 years • Usually obese at diagnosis • Can be due to hereditary or environmental factors • No islet cell antibodies • Decreased insulin production or decreased sensitivity to insulin • Oral anti-diabetic agents may improve blood glucose levels • Diabetic keto-acidosis is rare
  • 9. Gestational Diabetes • Onset usually in 2nd or 3rd trimester • Placental hormones reduces action of insulin • Treated with diet or insulin
  • 11.
  • 13.
  • 14.
  • 15.
  • 16. Diagnostic Criteria • Polyuria, Polyphagia , Polydipsia plus plasma glucose concentrations > 200 mg/dl • Fasting plasma glucose concentrations > 126 mg/dl • 2- hour post-parandial plasma glucose concentration > 200 mg/dl •Glycosylated hemoglobin
  • 18. Diagnostic range of blood sugar (plasma glucose) Normal glucose tolerance Impaired glucose tolerance Diabetes mellitus Fasting plasma glucose (mg/dL) <110 110-126 >126 Between 0-120 min (mg/dL) <200 <200 200 at least once 2 hours after glucose load (mg/dL) <140 >140, but <200 >200
  • 22.  The major components of the treatment of diabetes are: Management of DM • Diet and ExerciseA • Oral hypoglycaemic therapyB • Insulin TherapyC
  • 23. Dietary Considerations • BMI • Activity level • Age / Sex • Present food habits • Economic status • Complications in Diabetes • Treatment of Diabetes
  • 24.  Diet is a basic part of management in every case.  Dietary treatment should aim at: ◦ ensuring weight control ◦ providing nutritional requirements ◦ allowing good glycaemia control with blood glucose levels as close to normal as possible A. Diet
  • 25. The following principles are recommended as dietary guidelines for people with diabetes:  Dietary fat should provide 25-35% of total intake of calories but saturated fat intake should not exceed 10% of total energy.  Cholesterol consumption should be restricted and limited to 300 mg or less daily.  Protein intake can range between 10-15% total energy (0.8- 1 g/kg of desirable body weight).  Excessive salt intake is to be avoided. It should be particularly restricted in people with hypertension and those with nephropathy. A. Diet (cont.)
  • 26. Exercise • Provides physical fitness • Carbohydrate metabolism • Weight & insulin sensitivity • Risk factors for cardio- vascular disease • Blood pressure & Cardiac work
  • 27.  Physical activity promotes weight reduction and improves insulin sensitivity, thus lowering blood glucose levels. Exercise
  • 28. Considerations during exercise • Use proper footwear during exercise • Avoid exercise in extremes of temperature • Inspect feet daily • Avoid exercise in periods of poor metabolic control • Do not exercise empty or full stomach
  • 29. Monitoring A – A1C Levels {estimated average BS level} B – Blood pressure C – Cholesterol D – Diabetic education E – Eye Examination F – Foot Examination G – Blood Glucose Examination H – Health I – Indications & Referral
  • 31.  There are currently four classes of oral anti-diabetic agents: i. Biguanides ii. Sulphonylureas iii. Non-sulphonylureas iv. α-glucosidase inhibitors v. Thiazolidinediones (TZDs) B. Oral Anti-Diabetic Agents
  • 33. C. Insulin THERAPY Used in treatment of – • Type 1 Diabetes • Acute Conditions of Type 2 Diabetes
  • 34.
  • 35. 35 Delivery Methods  Insulin Syringe  Insulin Pen  Insulin Pump  Jet Injector
  • 39.
  • 40.
  • 41. Nursing Diagnosis 1) Imbalanced Nutrition Less Than Body Requirements R/T reduction of carbohydrate metabolism due to insulin deficiency, inadequate intake due to nausea and vomiting. 2) Fluid Volume Deficit related to osmotic diuresis from hyperglycemia, polyuria, decreased fluid intake. 3) Impaired Skin Integrity related to decreased sensory sensation, impaired circulation, decreased activity / mobilization, lack of knowledge of skin care. 4) Activity Intolerance related to weakness due to decreased energy production. 5) High risk of injury associated with decreased sensation sensory (visual), weakness, and hypoglycemia. 6) Anxiety related to a lack of knowledge (diabetes management), the ability to remember the less, diagnosis or treatment of a new way, cognitive limitations. 7) Risk for ineffective management of therapeutic rules at home due to a lack of knowledge about the condition of the therapeutic management, inadequate support systems.
  • 42. Nursing diagnosis ……(Contd.) Altered nutrition : less than body requirements •Abnormal glucose metabolism •Depletion of fat stores, cellular proteins •Decreased oral intake – dislike of prescribed diet, anorexia gastric fullness
  • 43. Nursing diagnosis ……(Contd.) Altered fluid –volume deficit •Osmotic diuresis •Vomiting •Diarrhea •Diabetic Keto-acidosis
  • 44. Nursing diagnosis ……(Contd.) Impaired skin integrity •Abnormal pressure distribution due to peripheral neuropathy •Delayed wound healing
  • 45. Nursing diagnosis ……(Contd.) Altered systemic tissue perfusion •Vascular abnormalities •Hypovolemia •Orthostatic hypotension
  • 46. Nursing Diagnosis Anxiety •Unfamiliar environment •Lack of understanding of diagnosis & management •Possible changes in life- style & roles
  • 47. Education • Diabetes Mellitus • Approaches Of Management • Dietary Requirements • Exercise Regimen • Oral Hypoglycemic Drugs • Insulin therapy • Complications • Foot care • Adherence to treatment & Follow-up
  • 48.  Patients should be educated to practice self-care. This allows the patient to assume responsibility and control of his / her own diabetes management. Self-care should include: ◦ Blood glucose monitoring ◦ Body weight monitoring ◦ Foot-care ◦ Personal hygiene ◦ Healthy lifestyle/diet or physical activity ◦ Identify targets for control ◦ Stopping smoking Self-Care
  • 49. “Of course too much is bad for you”