Development of mid & hind guts

The skin is divided into two parts: the superficial part, the epidermis; and the deep part, the dermis (Fig. 1.4). The epidermis is a stratified epithelium whose cells become flat tened as they mature and rise to the surface. On the palms of the hands and the soles of the feet, the epidermis is extremely thick, to withstand the wear and tear that occurs in these regions. In other areas of the body, for example, on the ante rior surface of the arm and forearm, it is thin. The dermis is composed of dense connective tissue containing many blood vessels, lymphatic vessels, and nerves. It shows considerable variation in thickness in different parts of the body, tending to be thinner on the anterior than on the posterior surface. It is thinner in women than in men. The dermis of the skin is connected to the underlying deep fascia or bones by the superficial fascia, otherwise known as subcutaneous tissue. The skin over joints always folds in the same place, the SKIN CREASES (Fig. 1.5). At these sites, the skin is thinner than elsewhere and is firmly tethered to underlying struc tures by strong bands of fibrous tissue. The appendages of the skin are the nails, hair follicles, sebaceous glands, and sweat glands. The nails are keratinized plates on the dorsal surfaces of the tips of the fingers and toes. The proximal edge of the plate is the root of the nail (see Fig. 1.5). With the exception of the distal edge of the plate, the nail is surrounded and overlapped by folds of skin known as nail folds. The sur face of skin covered by the nail is the nail bed (see Fig. 1.5). Hairs grow out of follicles, which are invaginations of the epidermis into the dermis (see Fig. 1.4). The folli cles lie obliquely to the skin surface, and their expanded extremities, called hair bulbs, penetrate to the deeper part of the dermis. Each hair bulb is concave at its end, and

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