Cryptosporidium hominis is a parasite with an infectious oocyst containing sporozoites that infect the gastrointestinal tract. It has a life cycle involving schizogony and production of gametocytes leading to oocysts shed in feces. Infection causes self-limiting diarrhea in immunocompetent hosts but severe, worsening diarrhea in immunocompromised patients. Diagnosis is via stool examination and staining techniques. Treatment options include nitazoxanide and azithromycin. Cryptosporidiosis is found worldwide but prevalence is higher in developing countries, being transmitted through contaminated water and causing outbreaks where water treatment is insufficient.