This document provides an overview of congestive heart failure (CHF), including its definition, causes, pathophysiology, clinical manifestations, diagnostic evaluation, and management. CHF is defined as a clinical syndrome where the heart cannot pump enough blood to meet the body's needs. It is most commonly caused by conditions that overload or damage the heart such as hypertension, heart attacks, and cardiomyopathy. Clinically, it presents with symptoms of fluid backup like dyspnea, edema, and fatigue. Diagnostic tests include chest x-rays, EKGs, blood tests like BNP, and echocardiography. Treatment focuses on managing symptoms, addressing the underlying cause, and preventing complications through medications, lifestyle changes, and potentially devices

1. Nothing can happen unless you first dream
Carl Sandburg

2. Congestive heart failure
Presentation and Diagnosis
The most common reason for hospitalization in
adults >65 years old
Dr Shahid Abbas
Consultant Interventional Cardiologist

3. Road Map
– Definition
– Causes and pathophysiology
– Types of heart failure
– Compensatory mechanism of heart failure
– Clinical manifestations
– Classification of heart failure
– Diagnostic evaluation
– Management

4. Definition
A clinical syndrome that develops when
the heart cannot maintain an adequate
cardiac output
The heart pumps blood inadequately,
leading to reduced blood flow, back-up
(congestion) of blood in the veins and
lungs Leading to
Other changes that may further weaken
the heart

5. 5
Etiology
• A syndrome of Pulmonary and/ or Systemic
congestion due to  C.O
• Heart is unable to pump enough blood to
meet tissues O2 requirements
 Pulmonary pressure  fluid in alveoli
(PULMONARY EDEMA)
 Systemic pressure  fluid in tissues
(PERIPHERAL EDEMA)

6. 6
Etiology
• Heart failure is caused by systemic
hypertension in 75% of cases
• About one third of clients experiencing
myocardial infarction also develop heart
failure
• Structural heart changes, such as valvular
dysfunction, cause pressure or volume
overload on the heart

7. Predisposing Cardiac Diseases
• Myocardial infarction
• Chronic ischemia
• Cardiomyopathy
• Arrhythmias
• Diastolic dysfunction
• Valvular diseases
– Aortic Stenosis
– Mitral Stenosis
– Mitral Regurgitation

8. Causes of congestive heart failure
(cont…)
• Severe lung disease (pulmonary hypertension)
• Severe anemia
• Overactive thyroid gland (hyperthyroidism)
• Underactive thyroid gland (hypothyroidism)
• Abnormal heart rhythms ( atrial fibrillation)
• Kidney failure

9. Cardiac Physiology
(remember this?)
• CO = SV x HR
• HR: parasympathetic and sympathetic tone
• SV: preload, afterload, contractility

10. Preload
• Passive stretch of muscle prior to contraction
• Measurement: Swan-Ganz
– LVEDP
• Really a function of LVEDV
• Affected by compliance
– Low compliance = higher LVEDP @ lower LVEDV
– False high estimate of preload
• Frank-Starling right?

11. Afterload
• Force opposing/stretching muscle after
contraction begins
• Measurement: SVR
• Really a function of:
– SVR
– Chamber radius (dilated cardiomyopathies)
– Wall thickness (hypertrophy)

12. Contractility
• Normal ability of the muscle to contract at a
given force for a given stretch, independent of
preload or afterload forces
• In other words:
– How healthy is your heart muscle?
• Ischemia, Hypertrophy (?), Muscle loss

13. CHF: the heart muscle
March 2013 ghennersdorf DGK ESC SES

14. CHF: the heart muscle sarcomere
March 2013 ghennersdorf DGK ESC SES

15. Pathophysiology
Renin + Angiotensinogen
Angiotensin I
Angiotensin II
Peripheral
Vasoconstriction
 Afterload
 Cardiac Output
Heart Failure
Salt & Water Retention
 Plasma Volume
 Preload
 Cardiac Workload
Edema
Aldosterone Secretion
Renin-angiotensin system

16. Heart Failure
• Pathophysiology
• A. Cardiac compensatory mechanisms
– 1.tachycardia
– 2.ventricular dilation-Starling’s law
– 3.myocardial hypertrophy
• Hypoxia leads to dec. contractility

17. Acute decompensated heart failure
Pulmonary edema, often life-threatening
• Early
–Increase in the respiratory rate
–Decrease in PaO2
• Later
–Tachypnea
–Respiratory acidemia

18. Acute Decompensated Heart Failure
(ADHF) Pulmonary Edema
Pulmonary edema begins with an increased
filtration through the loose junctions of the
pulmonary capillaries.
As the intracapillary pressure increases, normally
impermeable (tight) junctions between the alveolar cells
open, permitting alveolar flooding to occur.

19. END RESULT
FLUID OVERLOAD > Acute Decompensated Heart Failure
(ADHF)/Pulmonary Edema
Medical Emergency!

20. Person literally drowning in
secretions
Immediate Action Needed

21. MMildild
Heart Failure
(progression)
Drugs
Diet
Fluid
Restriction
Cardiogenic shock
Cardiomyopathy
CDHF(Pulmonary Edema) Severe End Stage
Irreversible
Needs new ventricle
VAD
IABP
VAD
IABP
Heart Transplant
Control With
Emergency-Upright, O2, morphine, etc

23. Ventricular remodeling

24. Classifying Heart Failure
• Anatomically
– Left versus Right
• Physiologically
– Systolic versus Diastolic
• Functionally
– How symptomatic is your patient?

25. Congestive heart failure
Types
• Left-sided heart failure
There are two types of left-sided heart failure
Systolic dysfunction
Diastolic dysfunction
• Right-sided heart failure

26. Left versus Right Failure
Left Heart Failure
- Dyspnea
- Dec. exercise tolerance
- Cough
- Orthopnea
- Pink, frothy sputum
Right Heart Failure
- Dec. exercise tolerance
- Edema
- HJR / JVD
- Hepatomegaly
- Ascites

27. Systolic versus Diastolic
Systolic– “can’t pump”
– Aortic Stenosis
– HTN
– Aortic Insufficiency
– Mitral Regurgitation
– Muscle Loss
• Ischemia
• Fibrosis
• Infiltration
Diastolic- “can’t fill”
– Mitral Stenosis
– Tamponade
– Hypertrophy
– Infiltration
– Fibrosis

30. Classification of heart failure
New York Heart Association (NYHA) Functional Classification
Class % of patients Symptoms
No symptoms or limitations in ordinary
physical activity
I 35%
Mild symptoms and slight limitation
during ordinary activity
II 35%
Marked limitation in activity even
during minimal activity. Comfortable
only at rest
III 25%
Severe limitation. Experiences
symptoms even at rest
IV 5%

31. Heart Failure
Clinical Manifestations
• Acute decompensated heart
failure (ADHF)
• Physical findings
• Orthopnea
• Dyspnea, tachypnea
• Use of accessory muscles
• Cyanosis
• Cool and clammy skin
•Physical findings
•*Cough with frothy,
blood-tinged sputum
•Breath sounds: Crackles,
wheezes, rhonchi
•Tachycardia
•Hypotension or
hypertension

32. ADHF/Pulmonary Edema
(advanced L side HF)
When PA WEDGE pressure is approx 30mmHg
– Signs and symptoms
• wheezing
• pallor, cyanosis
• Inc. HR and BP
• S3 gallop
• Rales,copious pink, frothy sputum

33. Congestive heart failure
Clinical manifestations
– Symptoms (back up of blood and fluid)
– Dyspnea
– Orthopnea
– Reduced exercise tolerance, lethargy,
fatigue
– Nocturnal cough
–Wheeze
– Ankle swelling
– Anorexia

34. Congestive heart failure
Clinical manifestations ( cont…)
–Signs
– Cachexia and muscle wasting
– Tachycardia
– Pulsus alternans
– Elevated jugular venous pressure
– Crepitations or wheeze
– Third heart sound
– Oedema
– Hepatomegaly (tender)
– Ascites

35. Clinical Data
• HEART SOUNDS!!!
• Systolic Murmurs
– Mitral Regurg
– Aortic Stenosis
• Diastolic Murmurs
– Mitral Stenosis
– Aortic Insufficiency
• S3: Rapid filling of a diseased ventricle

36. Symptoms

37. 37

38. 38
PULMONARY EDEMA
Rapid fluid accumulation in lung spaces that
has leaked from engorged pulmonary
capillaries
Etiology – most common cause is sudden
deterioration of LV function

39. 39
Cardiogenic Shock
Significant reduction in SV & CO causes drop in
pressure & poor tissue perfusion a/r/o LV MI
• Clinical signs:
–  BP,  pulse,  peripheral pulses
– confusion/ agitation (cerebral hypoxia)
– cold/ clammy skin
–  urine output
– Resp distress
– Chest pain

41. 41
(R) SIDED HF
Blood “BACKS UP” into venous circulation. High
oncotic pressure pushes fluids into tissues.
CLINICAL SIGNS:
 CVP SUDDEN WT. GAIN
 JVD DEPENDENT EDEMA
FATIGUE LIVER CONGESTION
LETHARGY ASCITES
ORTHOPNEA ANOREXIA

42. 42

43. What does this
show?

44. Can You Have RVF Without LVF?
• What is this called?
COR PULMONALE

45. What is present in this extremity, common to right sided HF?

46. Heart Failure
Complications
• Pleural effusion
• Atrial fibrillation (most common
dysrhythmia)
– Loss of atrial contraction (kick) -reduce CO by
10% to 20%
– Promotes thrombus/embolus formation inc.
risk for stroke
– Treatment may include cardioversion,
antidysrhythmics, and/or anticoagulants

47. Heart Failure
Complications
• **High risk of fatal dysrhythmias (e.g., sudden
cardiac death, ventricular tachycardia) with HF and
an EF <35%
– HF lead to severe hepatomegaly, especially with
RV failure
• Fibrosis and cirrhosis - develop over time
– Renal insufficiency or failure

48. Heart Failure
Diagnostic Studies
• Primary goal- determine underlying cause
– History and physical examination( dyspnea)
– Chest x-ray
– ECG
– Lab studies (e.g., cardiac enzymes, BNP- (beta
natriuretic peptide- normal value less than 100)
electrolytes
– EF

49. Clinical Data
• CXR
– Kerley’s lines : A and B
– Pulmonary Edema
– Cephalization
– Pleural Effusions (bilateral)
• EKG
– Left atrial enlargement
– Arrhythmias
– Hypertrophy (left or right)

50. Cardiomegaly Pulm Oedema

51. Cardiomegaly/ventricular remodeling occurs as heart overworked> changes in size, shape, and function
of heart after injury to left ventricle. Injury due to acute myocardial infarction or due to causes that inc.
pressure or volume overload as in Heart failure

52. Clinical Data
• Laboratory Data
• Chemistry
– Renal Function: Be Wary
• BNP
– Used in ER departments the world over
– Good negative correlation
– Need baseline for positivity
– Pulmonary versus cardiac dyspnea

53. Transesophageal
echocardiogram
TEE

54. But

56. 56

57. Goals of Treatment-ADHF/Pulmonary Edema)
MAD DOG
• Improve gas exchange
– Start O2/elevate HOB/intubate
– Morphine –dec anxiety/afterload
– A- (airway/head up/legs down)
– D- (Drugs) Dig not first now- but drugs as
• IV nitroglycerin; IV Nipride, Natrecor
– D- Diuretics
– O- oxygen /measure sats;
• Hemodynamics, careful observation
– G- blood gases
– Think physiology