This document provides guidance on performing an adult general physical examination. It outlines the initial steps, which include greeting the patient, introducing yourself, confirming patient identity, explaining the exam, ensuring a proper environment, obtaining consent, hand washing, draping the patient, and considering pain. It then describes aspects to examine such as handshake, body build, face, clothing, complexion, sounds, odors, posture, gait, and movements. Specific examination techniques are also mentioned, including examining the pallor, edema, nails, cyanosis, icterus, lymph nodes, and skin. Causes and characteristics of various physical findings are listed.