High altitude illness occurs when the body has difficulty adjusting to low oxygen levels at high elevations. Mild forms include acute mountain sickness with headaches and fatigue. More severe forms are high altitude cerebral edema, where the brain swells, and high altitude pulmonary edema, where the lungs fill with fluid. To prevent illness, people should ascend gradually to high elevations, stay hydrated, and rest adequately. If symptoms occur, descending to lower elevations provides the best treatment.