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Chapter 6 – Cell Membranes
Fluid Mosaic Model




Phospholipids form a bilayer which is like a
“lake” in which a variety of proteins “float.”
Phospholipids Bilayer
Forms Spontaneously in water


Vary in fatty acid chain length, degree of saturation, and phosphate
groups



Membranes may be up to 25 percent cholesterol


Flexible allowing lateral movement
of molecules


Fluidity depends on temperature
and lipid composition.
Components of the Fluid
       Mosaic Model
• Lipids
  – Phospholipids/ Cholesterol
• Proteins
  – Intergral
  – Peripheral
• Carbohydrates
Membrane Bounds Proteins
Two types of membrane proteins:


• Peripheral membrane proteins lack
  exposed hydrophobic groups and do
  not penetrate the bilayer.


• Integral membrane proteins have
  hydrophobic and hydrophilic regions
  or domains.
Transmembrane Proteins
• Type of integral
  protein

• Extend all the way
  through the
  phospholipid
  bilayer.
Selective Permeability
Some substances can     Passive transport:
pass through, but not   no outside energy
others                  required (diffusion).

What can pass:
- Small                 Active transport:
- Uncharged             energy required


Examples?
Diffusion
The process of
random movement
toward equilibrium

It is the net movement
from regions of
greater concentration
to regions of lesser
concentration.
What Controls the Speed of
           Diffusion?
- Diameter of the molecules or ions
- Temperature of the solution
-   Concentration Gradient
-   Electrochemical Gradient
-   When a cell is involved you also have
    to consider movement across a
    membrane.
Simple Diffusion
Small molecules pass directly through
the lipid bilayer.

Water and lipid-soluble molecules can
diffuse across the membrane.


Electrically charged and polar molecules
can NOT pass through easily.
Osmosis
The Diffusion of Water

Osmosis depends on the number of
solute particles present, not the type of
particles.
Hypertonic Solutions: High
  Solute Concentrations




        Cell Shrinks
Hypotonic Solutions: Low
 Solute Concentrations




      Cell Lyses in Animal Cells
Swells in Plant Cells (Turgor Pressure)
Isotonic Solutions: Equal
solute/water concentration




    Cell Remains the Same
Facilitated Diffusion
Passive Transport across a membrane using
an integral membrane protein


Channel proteins: have a central pore lined
with polar amino acids.


Carrier proteins: membrane proteins that bind
some substances and speed their diffusion
through the bilayer.
Channel Proteins
Specificity

Best Example are
Ion Channels

Most are “Gated”

Ligand-Gated       Rate and direction of ion movement
                   through channels depends on the
                   concentration gradient and the
                   distribution of electrical charge.
Voltage Gated
Membrane Potential
A charge imbalance across a membrane.

Represents lots of potential energy

Signals volatge-gated channels to open

Critical to ATP production during Cellular
Respiration or Photosynthesis
Carrier Proteins
Passive Transport

Directly binds to
  molecule

Then Changes shape
  to move the
  molecule across the
  membrane
Active Transport
Require Energy

Move molecules
AGAINST the
concentration gradient

Uniporters
Symporters
Antiporters
Large Molecule Transport
Endocytosis: bring       Exocytosis: Move
material into the cell   material out of the cell
using vesicles           using vesicles
Endocytosis
3 TYPES

Phagocytosis: Engulf
large molecules or even
whole cells making
hagosomes

Pinocytosis: Cellular
Drinking (small vesicles)

Receptor Mediated
Endocytosis: binds
specific targets

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BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
 

Chapter 6

  • 1. Chapter 6 – Cell Membranes
  • 2. Fluid Mosaic Model Phospholipids form a bilayer which is like a “lake” in which a variety of proteins “float.”
  • 3. Phospholipids Bilayer Forms Spontaneously in water Vary in fatty acid chain length, degree of saturation, and phosphate groups Membranes may be up to 25 percent cholesterol Flexible allowing lateral movement of molecules Fluidity depends on temperature and lipid composition.
  • 4. Components of the Fluid Mosaic Model • Lipids – Phospholipids/ Cholesterol • Proteins – Intergral – Peripheral • Carbohydrates
  • 5. Membrane Bounds Proteins Two types of membrane proteins: • Peripheral membrane proteins lack exposed hydrophobic groups and do not penetrate the bilayer. • Integral membrane proteins have hydrophobic and hydrophilic regions or domains.
  • 6. Transmembrane Proteins • Type of integral protein • Extend all the way through the phospholipid bilayer.
  • 7. Selective Permeability Some substances can Passive transport: pass through, but not no outside energy others required (diffusion). What can pass: - Small Active transport: - Uncharged energy required Examples?
  • 8. Diffusion The process of random movement toward equilibrium It is the net movement from regions of greater concentration to regions of lesser concentration.
  • 9. What Controls the Speed of Diffusion? - Diameter of the molecules or ions - Temperature of the solution - Concentration Gradient - Electrochemical Gradient - When a cell is involved you also have to consider movement across a membrane.
  • 10. Simple Diffusion Small molecules pass directly through the lipid bilayer. Water and lipid-soluble molecules can diffuse across the membrane. Electrically charged and polar molecules can NOT pass through easily.
  • 11. Osmosis The Diffusion of Water Osmosis depends on the number of solute particles present, not the type of particles.
  • 12. Hypertonic Solutions: High Solute Concentrations Cell Shrinks
  • 13. Hypotonic Solutions: Low Solute Concentrations Cell Lyses in Animal Cells Swells in Plant Cells (Turgor Pressure)
  • 14. Isotonic Solutions: Equal solute/water concentration Cell Remains the Same
  • 15. Facilitated Diffusion Passive Transport across a membrane using an integral membrane protein Channel proteins: have a central pore lined with polar amino acids. Carrier proteins: membrane proteins that bind some substances and speed their diffusion through the bilayer.
  • 16. Channel Proteins Specificity Best Example are Ion Channels Most are “Gated” Ligand-Gated Rate and direction of ion movement through channels depends on the concentration gradient and the distribution of electrical charge. Voltage Gated
  • 17. Membrane Potential A charge imbalance across a membrane. Represents lots of potential energy Signals volatge-gated channels to open Critical to ATP production during Cellular Respiration or Photosynthesis
  • 18. Carrier Proteins Passive Transport Directly binds to molecule Then Changes shape to move the molecule across the membrane
  • 19. Active Transport Require Energy Move molecules AGAINST the concentration gradient Uniporters Symporters Antiporters
  • 20. Large Molecule Transport Endocytosis: bring Exocytosis: Move material into the cell material out of the cell using vesicles using vesicles
  • 21. Endocytosis 3 TYPES Phagocytosis: Engulf large molecules or even whole cells making hagosomes Pinocytosis: Cellular Drinking (small vesicles) Receptor Mediated Endocytosis: binds specific targets