The lymphatic system collects excess tissue fluid and returns it to the bloodstream. Its components include lymphatic vessels, lymph nodes, and lymph ducts. The immune system protects the body from foreign organisms using lymphocytes, lymphoid tissue, and lymphoid organs like the spleen, thymus, and lymph nodes. Lymphocytes recognize and destroy pathogens. When activated by antigens, they proliferate into memory and effector cells. Disorders can affect the lymphatic vessels or immune function.
This PPT covers the concepts of Lymphatic system and Immunity. This includes functions of Lymphatic system, components of Lymphatic system, Lymphatic organs and tissues, formation and flow of lymph and composition of Lymph
The lymphatic system transports lymph fluid and assists the immune system. It is composed of lymphatic vessels, lymph nodes, the spleen, thymus, and lymphatic cells. Lymph fluid is collected from tissues by lymphatic capillaries and transported through a series of vessels, nodes, and ducts where it is filtered for pathogens. The system's immune cells help fight infection and disease. As the body ages, the thymus and immune function decline, making elderly people more susceptible to illness.
The lymphatic system helps fight infection and disease. It is composed of lymph vessels that carry lymph fluid containing white blood cells. Lymph fluid is similar to plasma but contains larger particles like bacteria and damaged cells. Lymph vessels connect to lymph nodes which filter the lymph and contain lymphocytes that fight infection. The largest lymph vessels are the thoracic duct and right lymphatic duct which drain lymph into the bloodstream. Disorders of the lymphatic system include lymphomas, lymphadenitis, and lymphedema.
The lymphatic system consists of lymph and lymphatic vessels that transport lymph throughout the body. Lymph is interstitial fluid that has entered lymphatic capillaries and contains lymphocytes, macrophages, viruses, bacteria, and cellular debris. The main components of the lymphatic system are lymph, lymphatic vessels, lymph nodes, lymphatic trunks and ducts, and lymphatic tissue. Lymph flows from lymphatic capillaries through vessels, nodes, trunks and ducts and eventually returns to the blood circulation via the subclavian veins. The lymphatic system functions to transport fluids and nutrients, support immune responses, and absorb dietary fats.
The lymphatic system consists of lymph, lymph vessels, lymph nodes, and lymphocyte-containing tissues. It collects fluid that leaks from blood vessels, known as lymph, and returns it to the circulatory system. The lymph flows through a network of thin-walled lymphatic vessels and passes through lymph nodes, which contain immune cells. Any foreign substances are filtered out before the lymph rejoins the bloodstream in larger veins in the neck.
types of circulatory system, function of lymphatic system, components of lymphatic system, and explaination of these components, formation of lymph and factors contributing ti n the drainage of lymph, types of lymphoid organ, blood supply of lymphoid organ clinical aspect
The document discusses the lymphatic system. It describes the location and microscopic features of lymphatic organs including lymph nodes, spleen, thymus, and tonsils. It explains the functions of the lymphatic system in reabsorbing excess fluid, transporting lipids, and facilitating immune responses. The components of the lymphatic system include lymph, lymphatic vessels, and lymphatic organs. It provides details on the anatomy and histology of these structures.
The lymphatic system carries fluid lost from capillaries back to the bloodstream through lymphatic vessels and ducts. It also transports fat and plays a major role in immunity. Lymph nodes along lymphatic pathways contain lymphocytes and macrophages that fight microbes. The tonsils, spleen, and thymus are lymphatic organs - the tonsils trap pathogens in the mouth and throat, the spleen filters the blood and destroys old red blood cells, and the thymus matures T cells that respond to foreign substances.
This PPT covers the concepts of Lymphatic system and Immunity. This includes functions of Lymphatic system, components of Lymphatic system, Lymphatic organs and tissues, formation and flow of lymph and composition of Lymph
The lymphatic system transports lymph fluid and assists the immune system. It is composed of lymphatic vessels, lymph nodes, the spleen, thymus, and lymphatic cells. Lymph fluid is collected from tissues by lymphatic capillaries and transported through a series of vessels, nodes, and ducts where it is filtered for pathogens. The system's immune cells help fight infection and disease. As the body ages, the thymus and immune function decline, making elderly people more susceptible to illness.
The lymphatic system helps fight infection and disease. It is composed of lymph vessels that carry lymph fluid containing white blood cells. Lymph fluid is similar to plasma but contains larger particles like bacteria and damaged cells. Lymph vessels connect to lymph nodes which filter the lymph and contain lymphocytes that fight infection. The largest lymph vessels are the thoracic duct and right lymphatic duct which drain lymph into the bloodstream. Disorders of the lymphatic system include lymphomas, lymphadenitis, and lymphedema.
The lymphatic system consists of lymph and lymphatic vessels that transport lymph throughout the body. Lymph is interstitial fluid that has entered lymphatic capillaries and contains lymphocytes, macrophages, viruses, bacteria, and cellular debris. The main components of the lymphatic system are lymph, lymphatic vessels, lymph nodes, lymphatic trunks and ducts, and lymphatic tissue. Lymph flows from lymphatic capillaries through vessels, nodes, trunks and ducts and eventually returns to the blood circulation via the subclavian veins. The lymphatic system functions to transport fluids and nutrients, support immune responses, and absorb dietary fats.
The lymphatic system consists of lymph, lymph vessels, lymph nodes, and lymphocyte-containing tissues. It collects fluid that leaks from blood vessels, known as lymph, and returns it to the circulatory system. The lymph flows through a network of thin-walled lymphatic vessels and passes through lymph nodes, which contain immune cells. Any foreign substances are filtered out before the lymph rejoins the bloodstream in larger veins in the neck.
types of circulatory system, function of lymphatic system, components of lymphatic system, and explaination of these components, formation of lymph and factors contributing ti n the drainage of lymph, types of lymphoid organ, blood supply of lymphoid organ clinical aspect
The document discusses the lymphatic system. It describes the location and microscopic features of lymphatic organs including lymph nodes, spleen, thymus, and tonsils. It explains the functions of the lymphatic system in reabsorbing excess fluid, transporting lipids, and facilitating immune responses. The components of the lymphatic system include lymph, lymphatic vessels, and lymphatic organs. It provides details on the anatomy and histology of these structures.
The lymphatic system carries fluid lost from capillaries back to the bloodstream through lymphatic vessels and ducts. It also transports fat and plays a major role in immunity. Lymph nodes along lymphatic pathways contain lymphocytes and macrophages that fight microbes. The tonsils, spleen, and thymus are lymphatic organs - the tonsils trap pathogens in the mouth and throat, the spleen filters the blood and destroys old red blood cells, and the thymus matures T cells that respond to foreign substances.
The lymphatic system consists of lymph, lymphatic vessels, lymphatic tissue, and lymphatic organs. Lymph is a clear fluid that transports tissue fluid, lymphocytes, bacteria, and cancer cells through lymphatic vessels and capillaries. The vessels converge in lymph nodes before draining into the subclavian veins. Primary lymphatic organs are the red bone marrow and thymus, which produce lymphocytes. Secondary lymphatic organs include lymph nodes, tonsils, spleen, Peyer's patches, and appendix, which filter lymph and mount immune responses.
The lymphatic system is part of the immune system. It also maintains fluid balance and plays a role in absorbing fats and fat-soluble nutrients.
The lymphatic or lymph system involves an extensive network of vessels that passes through almost all our tissues to allow for the movement of a fluid called lymph. Lymph circulates through the body in a similar way to blood.
There are about 600 lymph nodes in the body. These nodes swell in response to infection, due to a build-up of lymph fluid, bacteria, or other organisms and immune system cells.
A person with a throat infection, for example, may feel that their "glands" are swollen. Swollen glands can be felt especially under the jaw, in the armpits, or in the groin area. These are, in fact, not glands but lymph nodes.
The lymphatic system helps maintain fluid balance, absorbs fatty acids from the small intestine, and fights infection. It is composed of lymph, lymph vessels, lymph nodes, and organs like the spleen and thymus. Lymph forms when interstitial fluid enters lymph capillaries and is transported through increasingly large vessels before draining into the bloodstream via the thoracic duct or right lymphatic duct. Lymph nodes filter lymph and contains lymphocytes that help fight pathogens. The spleen and thymus also aid immunity.
The lymphatic system is an important part of the circulatory system that helps transport fat, remove interstitial fluid and toxins, and supports the immune system. It is comprised of lymph fluid, vessels, and nodes. Lymph fluid is formed from fluid that leaves blood vessels and transports through lymph vessels to lymph nodes, which filter the lymph. Major lymphatic ducts then return filtered lymph to the bloodstream. The document discusses the key components and functions of the lymphatic system, as well as ways to keep it healthy through diet, exercise, stress reduction, and deep breathing.
The lymphatic system returns excess tissue fluid to the bloodstream via lymphatic vessels and lymph nodes. Its main functions are drainage of interstitial fluid and participation in the immune response. The immune system protects the body from foreign organisms through fighting infections and conferring immunity.
The lymphatic system consists of lymph, lymph nodes, lymph vessels, the spleen, thymus, tonsils, bone marrow and skin-associated lymphoid tissues. The main cells of the lymphatic system are lymphocytes such as B cells, T cells, natural killer cells, and supporting cells that interact with and present antigens to lymphocytes. The lymphatic system protects the body from foreign materials, assists in fluid circulation, and transports dietary fats. The thymus gland aids in the maturation of T cells while the spleen filters blood and mounts an immune response to antigens. Lymph nodes are located around arteries and veins and filter lymph fluid draining tissues.
The kidneys are a pair of excretory organs located retroperitoneally on either side of the vertebral column. They remove waste and regulate water and electrolyte balance. Each kidney contains an inner medulla and outer cortex. The kidneys receive blood supply from the renal arteries and drain into the renal veins. They are important for regulating blood pressure and red blood cell production. Kidney diseases can cause hypertension, renal failure and require dialysis in severe cases.
This document summarizes the histology of the lymphatic system. It describes the main lymphoid organs as lymph nodes, spleen, thymus, and tonsils. Lymph nodes contain an outer cortex with lymphoid nodules and germinal centers, and an inner medulla with medullary cords and sinuses. The spleen has a capsule dividing it into white pulp with lymphoid nodules and red pulp with splenic cords and sinusoids. The thymus has a dark staining cortex containing immature lymphocytes and a light staining medulla with thymic corpuscles. Tonsils consist of lymphoid nodules in crypts, covered by stratified squ
The thymus is an organ located in the upper chest that plays a key role in immune system development. It contains two main areas - the cortex and medulla - which help lymphocytes mature. The thymus contains various cell types that interact to promote T cell differentiation and selection. Epithelial reticular cells form a framework and secrete hormones to guide lymphocyte development. By adolescence, the thymus begins to involute and lose much of its immune function.
The lymphatic system consists of lymphatic vessels, lymph nodes, and lymphoid organs that work together to drain excess tissue fluid, absorb fatty acids, and recognize and fight foreign pathogens. Lymphatic vessels are made up of a network of lymph capillaries, collecting vessels, and trunks that drain into the subclavian veins or thoracic duct. Lymph nodes filter lymph and initiate immune responses. Major lymphoid organs include the spleen, thymus, tonsils, and clusters of lymphoid tissue in the digestive system that help fight infection and remove old blood cells and platelets.
The lymphatic system consists of lymphatic tissues and vessels that work with the cardiovascular system to remove interstitial fluid from tissues, transport fats and lymphocytes, and provide immune defenses. Lymphatic tissues include the thymus, lymph nodes, spleen, and lymphatic nodules. Lymphatic vessels drain lymph from tissues into lymph nodes and eventually into the thoracic duct or right lymphatic duct, which empty into subclavian veins. The lymph nodes filter lymph before it returns to the bloodstream. Major groups of lymph nodes are located around joints, in the neck, chest, abdomen, and groin.
The lymphatic system is a network of tissues and organs that help rid the body of toxins, waste and other unwanted materials. The primary function of the lymphatic system is to transport lymph, a fluid containing infection-fighting white blood cells, throughout the body.
The lymphatic system is part of the circulatory system and comprises a network of lymphatic vessels that carry lymph fluid directionally towards the heart. The lymph system transports excess interstitial fluid, fatty acids, and immune cells. It has multiple functions including fluid removal from tissues, absorption and transport of fats, and transportation of white blood cells and antigen-presenting cells to lymph nodes to stimulate immune responses. The lymphatic system consists of lymphatic vessels, lymphoid tissues found throughout the body, and lymphoid organs such as lymph nodes, spleen, thymus, and tonsils that are involved in immune defenses.
The lymphatic system consists of lymph fluid, vessels called lymphatics, and lymphatic organs and tissues. Lymphatics originate as lymph capillaries that drain fluid from tissues and transport it through larger vessels to two main channels - the right lymphatic duct and thoracic duct - which empty into veins near the heart. Lymphatic organs include lymph nodes along lymphatic vessels, the spleen, thymus gland, and tonsils. These structures filter lymph, produce lymphocytes, and mount immune responses against pathogens.
The lymphatic system consists of lymph vessels, lymph nodes, and lymphoid tissues that work together to drain excess fluid from tissues, absorb and transport fatty acids from the gut, and help fight infection. Lymph is formed when interstitial fluid drains into initial lymphatic vessels and circulates through a network of vessels, nodes, ducts, and eventually returns to the bloodstream. Lymph nodes filter lymph as it circulates and contain immune cells that help fight pathogens. The major lymphatic ducts are the thoracic duct and right lymphatic duct which drain lymph into the bloodstream in the neck.
The document summarizes the lymphatic and immune systems. It describes the main structures of the lymphatic system as lymphatic vessels and lymph nodes. It then explains the main components of the immune system as lymphocytes, lymphoid tissue, and lymphoid organs. Finally, it discusses disorders that can affect these systems such as lymphangitis, mononucleosis, Hodgkin's disease, and non-Hodgkin's lymphoma.
The lymphatic system consists of lymph vessels, lymph nodes, and lymphoid organs that work together to drain excess interstitial fluid, transport fat and nutrients, and help the immune system fight pathogens. Lymph vessels carry lymph fluid and drain into lymph nodes which filter the lymph. Key lymphoid organs include the spleen, thymus, tonsils, Peyer's patches, and diffuse lymphatic tissues throughout the body. The lymphatic system plays an important role in immunity and maintains fluid balance.
The lymphatic system consists of lymph vessels, lymph nodes, the spleen, thymus, and bone marrow. It works with the immune and cardiovascular systems. Lymph is formed from excess interstitial fluid drained by lymphatic capillaries. It flows through lymph vessels and nodes which filter the lymph before returning it to blood circulation. The thymus and bone marrow are primary lymphatic organs where immune cells mature and multiply. Secondary organs like lymph nodes, spleen and tonsils initiate immune responses against pathogens.
The document outlines the key components and functions of the lymphatic and immune systems. It begins by defining the lymphatic system and explaining its role in absorbing excess fluid, transporting fats, producing lymphocytes, and defending the body. It then describes the structure of the lymphatic system including lymphatic vessels, lymph nodes, and other organs. Key differences between the lymphatic and immune systems are highlighted such as their circulatory nature and roles in long-term immunity. Finally, common diseases of the lymphatic system like lymphedema are discussed.
The document provides details on the structure and function of the lymphatic system. It describes lymph, lymphatic vessels, lymph nodes, and other lymphatic organs.
The document provides an overview of the respiratory system, including both the superior and inferior respiratory organs and tissues. It describes the main functions of respiration which involves gas exchange in the lungs and transport of gases in the blood between the respiratory and circulatory systems. Key organs of the respiratory system are described such as the nose, pharynx, larynx, trachea, bronchi, lungs and alveoli. The anatomy and tissues of these organs are summarized.
The lymphatic organs include lymph nodes, tonsils, and the spleen.
Lymph nodes are kidney-shaped and filter lymph. They have an outer cortex containing lymph follicles and sinuses, and an inner medulla containing medullary cords and sinuses. The spleen filters blood and produces blood cells. It has trabeculae dividing it into compartments containing white pulp with follicles and red pulp with cords and sinuses. Tonsils contain lymphoid tissue and are located in the palate, base of the tongue, and nasopharynx to protect the respiratory and digestive systems.
The lymphatic system consists of lymph, lymphatic vessels, lymphatic tissue, and lymphatic organs. Lymph is a clear fluid that transports tissue fluid, lymphocytes, bacteria, and cancer cells through lymphatic vessels and capillaries. The vessels converge in lymph nodes before draining into the subclavian veins. Primary lymphatic organs are the red bone marrow and thymus, which produce lymphocytes. Secondary lymphatic organs include lymph nodes, tonsils, spleen, Peyer's patches, and appendix, which filter lymph and mount immune responses.
The lymphatic system is part of the immune system. It also maintains fluid balance and plays a role in absorbing fats and fat-soluble nutrients.
The lymphatic or lymph system involves an extensive network of vessels that passes through almost all our tissues to allow for the movement of a fluid called lymph. Lymph circulates through the body in a similar way to blood.
There are about 600 lymph nodes in the body. These nodes swell in response to infection, due to a build-up of lymph fluid, bacteria, or other organisms and immune system cells.
A person with a throat infection, for example, may feel that their "glands" are swollen. Swollen glands can be felt especially under the jaw, in the armpits, or in the groin area. These are, in fact, not glands but lymph nodes.
The lymphatic system helps maintain fluid balance, absorbs fatty acids from the small intestine, and fights infection. It is composed of lymph, lymph vessels, lymph nodes, and organs like the spleen and thymus. Lymph forms when interstitial fluid enters lymph capillaries and is transported through increasingly large vessels before draining into the bloodstream via the thoracic duct or right lymphatic duct. Lymph nodes filter lymph and contains lymphocytes that help fight pathogens. The spleen and thymus also aid immunity.
The lymphatic system is an important part of the circulatory system that helps transport fat, remove interstitial fluid and toxins, and supports the immune system. It is comprised of lymph fluid, vessels, and nodes. Lymph fluid is formed from fluid that leaves blood vessels and transports through lymph vessels to lymph nodes, which filter the lymph. Major lymphatic ducts then return filtered lymph to the bloodstream. The document discusses the key components and functions of the lymphatic system, as well as ways to keep it healthy through diet, exercise, stress reduction, and deep breathing.
The lymphatic system returns excess tissue fluid to the bloodstream via lymphatic vessels and lymph nodes. Its main functions are drainage of interstitial fluid and participation in the immune response. The immune system protects the body from foreign organisms through fighting infections and conferring immunity.
The lymphatic system consists of lymph, lymph nodes, lymph vessels, the spleen, thymus, tonsils, bone marrow and skin-associated lymphoid tissues. The main cells of the lymphatic system are lymphocytes such as B cells, T cells, natural killer cells, and supporting cells that interact with and present antigens to lymphocytes. The lymphatic system protects the body from foreign materials, assists in fluid circulation, and transports dietary fats. The thymus gland aids in the maturation of T cells while the spleen filters blood and mounts an immune response to antigens. Lymph nodes are located around arteries and veins and filter lymph fluid draining tissues.
The kidneys are a pair of excretory organs located retroperitoneally on either side of the vertebral column. They remove waste and regulate water and electrolyte balance. Each kidney contains an inner medulla and outer cortex. The kidneys receive blood supply from the renal arteries and drain into the renal veins. They are important for regulating blood pressure and red blood cell production. Kidney diseases can cause hypertension, renal failure and require dialysis in severe cases.
This document summarizes the histology of the lymphatic system. It describes the main lymphoid organs as lymph nodes, spleen, thymus, and tonsils. Lymph nodes contain an outer cortex with lymphoid nodules and germinal centers, and an inner medulla with medullary cords and sinuses. The spleen has a capsule dividing it into white pulp with lymphoid nodules and red pulp with splenic cords and sinusoids. The thymus has a dark staining cortex containing immature lymphocytes and a light staining medulla with thymic corpuscles. Tonsils consist of lymphoid nodules in crypts, covered by stratified squ
The thymus is an organ located in the upper chest that plays a key role in immune system development. It contains two main areas - the cortex and medulla - which help lymphocytes mature. The thymus contains various cell types that interact to promote T cell differentiation and selection. Epithelial reticular cells form a framework and secrete hormones to guide lymphocyte development. By adolescence, the thymus begins to involute and lose much of its immune function.
The lymphatic system consists of lymphatic vessels, lymph nodes, and lymphoid organs that work together to drain excess tissue fluid, absorb fatty acids, and recognize and fight foreign pathogens. Lymphatic vessels are made up of a network of lymph capillaries, collecting vessels, and trunks that drain into the subclavian veins or thoracic duct. Lymph nodes filter lymph and initiate immune responses. Major lymphoid organs include the spleen, thymus, tonsils, and clusters of lymphoid tissue in the digestive system that help fight infection and remove old blood cells and platelets.
The lymphatic system consists of lymphatic tissues and vessels that work with the cardiovascular system to remove interstitial fluid from tissues, transport fats and lymphocytes, and provide immune defenses. Lymphatic tissues include the thymus, lymph nodes, spleen, and lymphatic nodules. Lymphatic vessels drain lymph from tissues into lymph nodes and eventually into the thoracic duct or right lymphatic duct, which empty into subclavian veins. The lymph nodes filter lymph before it returns to the bloodstream. Major groups of lymph nodes are located around joints, in the neck, chest, abdomen, and groin.
The lymphatic system is a network of tissues and organs that help rid the body of toxins, waste and other unwanted materials. The primary function of the lymphatic system is to transport lymph, a fluid containing infection-fighting white blood cells, throughout the body.
The lymphatic system is part of the circulatory system and comprises a network of lymphatic vessels that carry lymph fluid directionally towards the heart. The lymph system transports excess interstitial fluid, fatty acids, and immune cells. It has multiple functions including fluid removal from tissues, absorption and transport of fats, and transportation of white blood cells and antigen-presenting cells to lymph nodes to stimulate immune responses. The lymphatic system consists of lymphatic vessels, lymphoid tissues found throughout the body, and lymphoid organs such as lymph nodes, spleen, thymus, and tonsils that are involved in immune defenses.
The lymphatic system consists of lymph fluid, vessels called lymphatics, and lymphatic organs and tissues. Lymphatics originate as lymph capillaries that drain fluid from tissues and transport it through larger vessels to two main channels - the right lymphatic duct and thoracic duct - which empty into veins near the heart. Lymphatic organs include lymph nodes along lymphatic vessels, the spleen, thymus gland, and tonsils. These structures filter lymph, produce lymphocytes, and mount immune responses against pathogens.
The lymphatic system consists of lymph vessels, lymph nodes, and lymphoid tissues that work together to drain excess fluid from tissues, absorb and transport fatty acids from the gut, and help fight infection. Lymph is formed when interstitial fluid drains into initial lymphatic vessels and circulates through a network of vessels, nodes, ducts, and eventually returns to the bloodstream. Lymph nodes filter lymph as it circulates and contain immune cells that help fight pathogens. The major lymphatic ducts are the thoracic duct and right lymphatic duct which drain lymph into the bloodstream in the neck.
The document summarizes the lymphatic and immune systems. It describes the main structures of the lymphatic system as lymphatic vessels and lymph nodes. It then explains the main components of the immune system as lymphocytes, lymphoid tissue, and lymphoid organs. Finally, it discusses disorders that can affect these systems such as lymphangitis, mononucleosis, Hodgkin's disease, and non-Hodgkin's lymphoma.
The lymphatic system consists of lymph vessels, lymph nodes, and lymphoid organs that work together to drain excess interstitial fluid, transport fat and nutrients, and help the immune system fight pathogens. Lymph vessels carry lymph fluid and drain into lymph nodes which filter the lymph. Key lymphoid organs include the spleen, thymus, tonsils, Peyer's patches, and diffuse lymphatic tissues throughout the body. The lymphatic system plays an important role in immunity and maintains fluid balance.
The lymphatic system consists of lymph vessels, lymph nodes, the spleen, thymus, and bone marrow. It works with the immune and cardiovascular systems. Lymph is formed from excess interstitial fluid drained by lymphatic capillaries. It flows through lymph vessels and nodes which filter the lymph before returning it to blood circulation. The thymus and bone marrow are primary lymphatic organs where immune cells mature and multiply. Secondary organs like lymph nodes, spleen and tonsils initiate immune responses against pathogens.
The document outlines the key components and functions of the lymphatic and immune systems. It begins by defining the lymphatic system and explaining its role in absorbing excess fluid, transporting fats, producing lymphocytes, and defending the body. It then describes the structure of the lymphatic system including lymphatic vessels, lymph nodes, and other organs. Key differences between the lymphatic and immune systems are highlighted such as their circulatory nature and roles in long-term immunity. Finally, common diseases of the lymphatic system like lymphedema are discussed.
The document provides details on the structure and function of the lymphatic system. It describes lymph, lymphatic vessels, lymph nodes, and other lymphatic organs.
The document provides an overview of the respiratory system, including both the superior and inferior respiratory organs and tissues. It describes the main functions of respiration which involves gas exchange in the lungs and transport of gases in the blood between the respiratory and circulatory systems. Key organs of the respiratory system are described such as the nose, pharynx, larynx, trachea, bronchi, lungs and alveoli. The anatomy and tissues of these organs are summarized.
The lymphatic organs include lymph nodes, tonsils, and the spleen.
Lymph nodes are kidney-shaped and filter lymph. They have an outer cortex containing lymph follicles and sinuses, and an inner medulla containing medullary cords and sinuses. The spleen filters blood and produces blood cells. It has trabeculae dividing it into compartments containing white pulp with follicles and red pulp with cords and sinuses. Tonsils contain lymphoid tissue and are located in the palate, base of the tongue, and nasopharynx to protect the respiratory and digestive systems.
The document discusses several lymphatic organs: the spleen, lymph nodes, and tonsils. The spleen is a single organ that filters blood and mounts immune responses. It has a thick capsule, trabeculae that divide it into compartments, white pulp containing follicles with central arterioles, and red pulp with splenic cords and sinusoids. Lymph nodes filter lymph and mount immunity. They have a thin capsule, trabeculae arising from the capsule, cortex and medulla regions. The tonsils include the palatine, lingual, and pharyngeal tonsils which are partially encapsulated lymphatic tissue located in the oral cavity and nasopharynx that protect from bacteria.
Immuniy, Antigen and Antibody, Hypersensitivity reactions and ocular corelati...Raju Kaiti
This document discusses antigen, antibody, and complement systems and types of immune responses and hypersensitivity reactions. It provides an overview of innate and adaptive immunity, cells involved in the immune system including B cells, T cells, and macrophages. It describes the properties of antigens and antibodies as well as the components, functions, and activation pathways of the complement system. The document also discusses the four types of hypersensitivity reactions (type I-IV) and provides examples of conditions that fall under each type of hypersensitivity.
The lymphoid system consists of cells, tissues, and organs that protect the body from foreign invaders. The main cells are lymphocytes like T cells, B cells, and NK cells. Lymphoid tissues include lymph nodes, spleen, tonsils, and Peyer's patches. The thymus and bone marrow are primary lymphoid organs where lymphocytes develop. Secondary lymphoid organs activate lymphocytes and produce an immune response against antigens. Lymph nodes filter lymph and mount immune responses. The spleen filters blood and mounts responses in its white pulp.
The document summarizes epitope prediction and its algorithms. It discusses that epitopes are the portions of antigens responsible for antigen-antibody specificity. There are two main types of epitopes: sequential/continuous epitopes recognized by T helper cells and conformational/discontinuous epitopes recognized by both T and B cells. It then describes several computational algorithms used for predicting B-cell and T-cell epitopes, including Hopp & Woods, Welling's method, Karplus & Schultz parameters, and Kolaskar & Tongaonkar's method. Finally, it lists several databases and servers that can be used for epitope prediction, such as SYFPEITHI, MHCPEP, and EPIM
This document provides an overview of the anatomy and physiology of the respiratory system. It begins by outlining the major conducting structures of the respiratory system from the nose to the alveoli. It then describes each structure in more detail, including their location, tissue composition, and functions. Key points covered include the protective and warming functions of the nose, the roles of the pharynx, larynx, trachea, bronchi and terminal bronchioles in conducting air, and the gas exchange that occurs across the respiratory membrane in the alveoli.
The Lymphatic System & Lymphoid Organs And Tissuesmsu
The lymphatic system consists of lymphatic vessels, lymph nodes, and lymphoid tissues that work together to return interstitial fluid to the bloodstream, transport fat from the digestive tract, and help the body fight infection. Lymphatic vessels originate as microscopic capillaries that drain into larger collecting vessels, trunks, and ducts. The right lymphatic duct and thoracic duct are the two main lymphatic trunks that return lymph to the blood circulation. Lymphoid tissues include the lymph nodes, spleen, thymus, and bone marrow that contain lymphocytes like T cells and B cells which help the immune system fight pathogens and cancer cells.
This document discusses antigens and antibodies. It defines antigens as any molecule that can bind specifically to an antibody. Antigens include sugars, lipids, proteins and more. They can be found on microbes or in the environment. The document discusses the properties of antigens including their ability to induce immune responses or tolerance. It also discusses immunogens versus haptens. Factors that influence antigen immunogenicity are also covered such as molecular size, composition, and an antigen's susceptibility to processing and presentation. The role of adjuvants in enhancing immune responses is also summarized.
The document discusses antigens, immunogens, and the major histocompatibility complex (MHC). It describes how antigens are recognized by antibodies or T cell receptors, with immunogens being antigens that can trigger an immune response. The ability of immunogens to stimulate the immune system depends on their nature and genetic coding of MHC, which combines with immunogens for T cell recognition. MHC molecules present antigen peptides and are encoded by genes that confer the ability to mount immune responses.
Antibodies are Y-shaped proteins made up of light and heavy chains that bind to antigens. There are five major classes of antibodies (IgG, IgM, IgA, IgE, IgD) that have different structures and functions. Monoclonal antibodies derived from a single clone are specific for a single epitope, making them useful for research, diagnostics and therapeutics. Monoclonal antibodies find applications in diagnostic tests, diagnostic imaging, immunotoxins to treat cancer, and clearing pathogens from the body. Antibody engineering techniques allow humanization of mouse antibodies for improved safety.
The document discusses antigens, immunogens, epitopes, and major histocompatibility complex (MHC). It defines antigens and immunogens as molecules that can induce an immune response. Epitopes are the specific sites on antigens that antibodies and T cell receptors bind to. MHC proteins present antigen fragments to T cells and are encoded by polymorphic genes that play a role in transplant compatibility.
The lymphatic system includes lymph vessels, lymph nodes, and lymphoid organs that work to maintain fluid balance, absorb lipids, filter the blood, and participate in immunity. The lymph vessels carry lymph fluid away from tissues and into the venous circulation. Lymph nodes filter lymph and activate the immune system. Major lymphoid organs are the spleen, thymus, and tonsils, which help fight infection and store blood.
The document summarizes adaptive immunity and the immune system. It describes the two types of adaptive immunity - active and passive, which can be acquired naturally or artificially. It also details the roles of B cells and T cells in humoral and cell-mediated immunity, including antibody production, antigen recognition, and immune memory. Hypersensitivities are immune reactions beyond normal responses, classified into four types based on mechanisms.
The document provides an overview of immunohistochemical (IHC) techniques. It discusses the basic principles of IHC, including antigen-antibody reactions and the use of primary and secondary antibodies. It also describes different IHC staining methods such as direct, indirect, and peroxidase-antiperoxidase methods. Key enzymes and chromogens used in IHC are discussed, as well as factors that influence antibody binding such as dilution, incubation time and temperature.
Adaptive immunity involves both humoral and cellular responses. B-cells produce antibodies that circulate in the blood and lymph to neutralize pathogens and toxins. T-cells recognize intracellular pathogens through antigen presentation and induce cytotoxic killing of infected cells. Antibodies and T-cells are activated through antigen recognition and work together to provide long-lasting adaptive immunity against specific pathogens. Vaccines utilize this immune memory to safely induce immunity against harmful diseases.
This document contains lecture notes for Biology 151 Introduction to Immunology. It discusses antigens and immunogens, factors that influence immunogenicity such as foreignness, molecular size, and adjuvants. It also provides instructions for a journal article assignment and outlines topics to be covered including antibody structure and classes.
- Immunoglobulins are bifunctional proteins that must interact with a small number of specialized molecules like Fc receptors and complement proteins, while also recognizing an infinite array of antigenic determinants.
- They achieve this through a domain structure that provides both structural conservation and infinite variability. Immunoglobulin domains form a beta-barrel structure and are found in many proteins beyond antibodies.
- Within the variable regions, hypervariable loops provide the diversity in antigen recognition, supported by a conserved framework structure. The combination of loops and framework allows recognition of countless antigens.
The document provides information about the lymphatic system, lymphoid organs, and tissues. It discusses how fluid filters from capillaries into the interstitial space and how the lymphatic system removes excess fluid and proteins. It describes the structure and function of lymphatic vessels, lymph nodes, and other lymphoid tissues like the spleen, thymus, tonsils, and mucosa-associated lymphoid tissue. The main roles of these tissues are to filter lymph, activate immune responses, and provide sites for immune cell proliferation and surveillance.
The document discusses the anatomy and physiology of the lymphatic system. It defines the lymphatic system as a network of tissues and organs that help rid the body of toxins, waste, and other unwanted materials. The key components include lymph, lymphatic vessels, lymph nodes, the spleen, thymus, tonsils, and mucosa-associated lymphoid tissue. The main functions of the lymphatic system are to transport lymph, drain excess tissue fluid, transport dietary lipids, and carry out immune responses.
The lymphatic system returns interstitial fluid and leaked plasma proteins back to the blood. It consists of a network of lymphatic vessels and lymphoid tissues scattered throughout the body. Lymph is composed of interstitial fluid that has entered lymphatic capillaries from tissues. It flows from capillaries through collecting vessels and trunks before draining into the subclavian veins. The lymphatic system works with the immune system and contains lymphocytes that help fight pathogens and cancer cells. Primary lymphatic organs like the bone marrow and thymus gland produce lymphocytes while secondary organs like lymph nodes, spleen, tonsils, and Peyer's patches help the immune response.
The lymphatic system is a drainage system that works alongside the venous system to remove tissue fluid from interstitial spaces. Lymph capillaries absorb excess tissue fluid and transport it through lymphatic vessels to lymph nodes, where it is filtered. The filtered lymph then drains into either the thoracic duct or right lymphatic duct and returns to the bloodstream. The lymphatic system removes larger particles from tissues and transports mature lymphocytes throughout the body. Key components include lymph vessels, central lymphoid tissues like bone marrow and thymus, peripheral lymphoid organs like lymph nodes and spleen, and circulating lymphocytes in the bloodstream.
The lymphatic system transports a fluid called lymph throughout the body via lymphatic vessels and works closely with the circulatory system. Its main functions include draining excess fluid from tissues, absorbing and transporting fats and vitamins, and returning plasma proteins to the bloodstream. The lymphatic system also plays an important role in immunity by transporting white blood cells and allowing them to mature and fight infection in lymph nodes and other lymphatic organs like the spleen.
The lymphatic system returns fluid to the bloodstream, removes antigens from tissues, and exposes antigens to the immune system. It consists of lymph, lymphatic vessels, lymph nodes, diffuse lymphoid tissues like tonsils, and lymphoid organs like the spleen and thymus gland. Lymph passes through a series of vessels and lymph nodes before draining into the subclavian veins near the neck.
The lymphatic system is a network of organs, vessels and tissues that helps maintain fluid balance in the body's tissues, transports fats and provides immune responses. It consists of lymph capillaries that drain tissue fluid and transport it through lymph vessels, lymph nodes and ducts back to the bloodstream. The lymphatic system helps filter bacteria and toxins from tissues, transports fats and immune cells, and maintains proper fluid levels in between cells. Key components include lymph nodes that filter lymph as it circulates through the body, and organs like the spleen, thymus and mucosa-associated lymphoid tissue that help immune responses.
The lymphatic system transports lymph fluid and immune cells throughout the body. It is made up of lymphatic vessels, lymph nodes, the spleen, thymus, tonsils, adenoids, and bone marrow. Lymphatic vessels carry lymph fluid and drain extra fluid from tissues before returning it to the bloodstream. Lymph nodes filter the lymph and contain lymphocytes that help fight infection and disease. Other lymphoid organs include the spleen, thymus, tonsils, adenoids and skin nodules that help the immune system develop and respond.
Secondary lymphoid organs initiate immune responses by allowing lymphocytes and antigen presenting cells to interact. These organs include lymph nodes, the spleen, tonsils, and mucosa-associated lymphoid tissue found in the digestive and respiratory tracts. They are connected by both the circulatory and lymphatic systems which transport immune cells and antigens between tissues and lymphoid organs. Within secondary lymphoid organs, T cell and B cell zones allow interactions that initiate adaptive immune responses to infections and foreign substances that enter the body.
The lymphatic system returns leaked fluid from tissues back to the bloodstream. It consists of lymphatic vessels, lymph nodes, and lymphoid organs. Lymphatic vessels collect fluid from tissues into lymph, which is transported towards the heart by muscle contractions, breathing, and one-way valves in vessels. Lymph nodes filter lymph and activate immune cells. The spleen, thymus, tonsils, Peyer's patches, and mucosa-associated lymphoid tissue help the immune system develop and respond to pathogens.
The document summarizes the lymphatic and immune systems. It discusses the organization of the lymphatic system including vessels, lymph nodes, thymus and spleen. It explains how the lymphatic system is related to and works with the circulatory system, and the role of lymphoid tissues and lymphocytes in the body's defense. It provides an introduction to the immune system and its focus on lymphocyte activity.
The lymphatic system consists of lymph, lymphatic vessels, lymph nodes, and lymphatic tissues. Lymph is formed from interstitial fluid that has filtered from blood capillaries. It is transported unidirectionally through lymphatic vessels by skeletal muscle and respiratory pumping action. Lymph vessels branch and join, eventually forming two main ducts that drain into veins in the neck. Lymph passes through lymph nodes, which filter lymph and activate immune cells. Together with organs like the spleen and thymus, the lymphatic system helps maintain fluid balance, absorb fats, and fight infection.
The document provides an overview of the lymphatic system. It describes that the lymphatic system consists of lymph, lymph vessels, lymph nodes, lymph organs like the spleen and thymus, diffuse lymphoid tissue like tonsils, and bone marrow. The main components and their functions are then described in more detail. This includes the production and circulation of lymph, structure and role of lymph nodes, thymus and spleen, and how the lymphatic system helps maintain fluid balance, absorb fats, and plays an important role in immunity.
The lymphatic system maintains fluid balance, protects the body from infection and disease, and aids in immunity, lipid absorption, and fluid recovery. It is composed of lymphatic capillaries that absorb interstitial fluid and immune cells, lymphatic vessels that contain valves to prevent backflow, and lymph nodes that filter lymph. The lymph eventually drains into the subclavian veins. When lymphatic drainage is impaired, severe edema can occur.
A good read for undergraduate students in Pharmacy studying at the University of Mumbai. I will highly recommend Principles of Anatomy and Physiology by Tortora et al. All copyright to the original authors and publishers.
The document discusses the lymph and lymphatic system. It describes the lymph as a fluid that circulates through the lymphatic system, collecting fluids and proteins from tissues and returning them to the blood. The lymphatic system functions to remove cellular waste, transport fatty acids and immune cells, and absorb fluids. The lymphatic system includes lymph vessels, lymph nodes, and organs like the spleen, thymus, and tonsils. Lymph is formed from interstitial fluid and circulates through one-way vessels before emptying into the subclavian veins.
Lymphoid organs concerned with development and differentiation of lymphocyte.gives specific and non specific immune response against pathogen enters into the body .Lymphoid organs are classified into three categories ;primary lymphoid organs e.g.thymus and bone marrow (involved in lymphocyte development ):secondary lymphoid organs e.g.Lymph nodes ,Spleen,MALT(involved in Ag and lymphocyte interaction and elimination of pathogen).Tertiary lymphoid organs e.g.CALT(import lymphocyte during inflammation ).
The lymphatic system helps maintain fluid balance and protects the body from pathogens. It consists of lymph vessels, lymph nodes, and organs like the spleen, thymus, and tonsils. The lymphatic system returns fluid and large molecules to the blood, absorbs and transports fats, and plays a key role in immunity by screening body fluids for pathogens. Lymph flows through vessels and nodes before draining into the blood through the thoracic duct or right lymphatic duct.
The lymphatic system is a network of tissues and organs that helps maintain fluid balance in the body, absorb fats and transport white blood cells. It collects excess fluid from tissues as lymph, transports it through vessels and ducts, and returns it to the bloodstream. The main parts include lymph, lymph vessels, lymph nodes, the spleen and thymus. Diseases can occur if the system is blocked or infected, such as lymphoma, lymphadenitis, and lymphedema.
The document provides an overview of key concepts in nutrition and health, including:
1) The six classes of nutrients - carbohydrates, fats, proteins, vitamins, minerals, and water. Carbohydrates, fats, and proteins provide energy and are known as energy-yielding nutrients.
2) Dietary guidelines and recommendations including the Dietary Reference Intakes, Acceptable Macronutrient Distribution Ranges, and Dietary Guidelines for Americans.
3) Factors that influence food selection and healthy versus unhealthy lifestyle choices as they relate to nutrition and risk of disease.
The document describes the structure and function of the respiratory system. It begins by outlining the key components of respiration including pulmonary ventilation, gas exchange in the lungs and blood, and transport of gases. It then details the anatomy of the major respiratory organs including the nose, pharynx, larynx, trachea, bronchi, lungs and associated structures. It explains how air moves through the conducting zone to the respiratory zone where gas exchange occurs in the alveoli. The roles of surrounding tissues like pleura and muscles in breathing are also summarized.
This document discusses the structure and function of the cardiovascular system. It describes the different types of blood vessels including arteries, veins, and capillaries. It explains the layers of blood vessels and how blood flows from the heart through the arteries, capillaries and veins before returning to the heart. Key concepts covered include blood pressure, resistance, cardiac output, hormones that regulate blood pressure, and normal blood pressure readings.
The document summarizes the cardiovascular system, specifically focusing on the heart. It describes how the heart is composed of two pumps divided into four chambers that comprise the pulmonary and systemic circuits. Deoxygenated blood enters the right atrium from the body and is pumped to the lungs by the right ventricle. Oxygenated blood returns to the left atrium from the lungs and is pumped back out to the body by the left ventricle. The document outlines the layers surrounding the heart, the anatomy and function of the four chambers, and how the heart valves ensure one-way blood flow through the heart during the cardiac cycle.
Blood is composed of plasma and formed elements including red blood cells, white blood cells, and platelets. When a blood sample is centrifuged, it separates into three layers - plasma on top, red blood cells on the bottom, and a buffy coat containing white blood cells and platelets between the two layers. Red blood cells contain hemoglobin and transport oxygen throughout the body while undergoing continuous production and destruction regulated by erythropoietin.
The document summarizes key aspects of the endocrine system. It describes how the endocrine system works with the nervous system to regulate metabolic processes via hormones transported through the blood. It identifies the major endocrine glands that produce hormones, such as the pituitary, thyroid, and adrenal glands. It explains the two main mechanisms by which hormones act on target cells: water-soluble hormones bind to cell surface receptors and trigger intracellular signaling cascades, while lipid-soluble hormones diffuse into cells and directly influence gene expression.
Ch 26 fluid, electrolyte, and acid base balance spring 2015Ronaldo Paulino
The document discusses fluid, electrolyte, and acid-base balance in the human body. It covers topics like water compartments, fluid movement between compartments, and the regulation of fluid volume and electrolyte concentrations. Key regulatory mechanisms involve hormones like antidiuretic hormone, aldosterone, and natriuretic peptides which act on the kidneys to control water and electrolyte retention and excretion. Imbalances can occur if fluid/electrolyte gains do not equal losses and are corrected through homeostatic responses.
Can coffee help me lose weight? Yes, 25,422 users in the USA use it for that ...nirahealhty
The South Beach Coffee Java Diet is a variation of the popular South Beach Diet, which was developed by cardiologist Dr. Arthur Agatston. The original South Beach Diet focuses on consuming lean proteins, healthy fats, and low-glycemic index carbohydrates. The South Beach Coffee Java Diet adds the element of coffee, specifically caffeine, to enhance weight loss and improve energy levels.
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardso...rightmanforbloodline
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardson, Verified Chapters 1 - 18, Complete Newest Version
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardson, Verified Chapters 1 - 18, Complete Newest Version
TEST BANK For Accounting Information Systems, 3rd Edition by Vernon Richardson, Verified Chapters 1 - 18, Complete Newest Version
Comprehensive Rainy Season Advisory: Safety and Preparedness Tips.pdfDr Rachana Gujar
The "Comprehensive Rainy Season Advisory: Safety and Preparedness Tips" offers essential guidance for navigating rainy weather conditions. It covers strategies for staying safe during storms, flood prevention measures, and advice on preparing for inclement weather. This advisory aims to ensure individuals are equipped with the knowledge and resources to handle the challenges of the rainy season effectively, emphasizing safety, preparedness, and resilience.
MBC Support Group for Black Women – Insights in Genetic Testing.pdfbkling
Christina Spears, breast cancer genetic counselor at the Ohio State University Comprehensive Cancer Center, joined us for the MBC Support Group for Black Women to discuss the importance of genetic testing in communities of color and answer pressing questions.
International Cancer Survivors Day is celebrated during June, placing the spotlight not only on cancer survivors, but also their caregivers.
CANSA has compiled a list of tips and guidelines of support:
https://cansa.org.za/who-cares-for-cancer-patients-caregivers/
Letter to MREC - application to conduct studyAzreen Aj
Application to conduct study on research title 'Awareness and knowledge of oral cancer and precancer among dental outpatient in Klinik Pergigian Merlimau, Melaka'
This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
R3 Stem Cell Therapy: A New Hope for Women with Ovarian FailureR3 Stem Cell
Discover the groundbreaking advancements in stem cell therapy by R3 Stem Cell, offering new hope for women with ovarian failure. This innovative treatment aims to restore ovarian function, improve fertility, and enhance overall well-being, revolutionizing reproductive health for women worldwide.
3. The Lymphatic and Immune Systems
• Lymphatic system
– Main function is to return excess tissue fluid to blood
vascular system
– Lymphatic vessels collect tissue fluid
• Immune system
– Protects our bodies from foreign organisms
– Confers immunity to disease
– Main components
• Lymphocytes, lymphoid tissue, and lymphoid organs
4. The Lymphatic System
• Lymphatic vessels collect tissue fluid from loose
connective tissue
– Carry fluid to great veins in the neck
– Fluid flows only toward the heart
– Once tissue fluid is within lymphatic vessels it is termed
lymph
• Functions of lymphatic vessels – collect excess
tissue fluid and blood proteins
• Return tissue fluid and blood proteins to
bloodstream
5. Orders of Lymphatic Vessels
• Lymph capillaries – smallest
lymph vessels
– First to receive lymph
• Lymphatic collecting vessels –
collect from lymph capillaries
– Lymph nodes are scattered
along collection vessels
Lymphatic system
Lymph duct
Lymph trunk
Lymph node
Lymphatic
capillary
Blood
capillaries
Lymphatic
collecting
vessels, with
valves
(a) Structural relationship between a capillary
bed of the blood vascular system and
lymphatic capillaries
Heart
Arterial systemVenous system
6. Orders of Lymphatic Vessels
• Lymph nodes
– Scattered along collecting vessels
• Lymph trunks
– Collect lymph from collecting vessels
• Lymph ducts
– Empty into veins of the neck
7. Lymphatic Capillaries
• Located near blood capillaries
• Receive tissue fluid from CT
– Increased volume of tissue fluid
• Minivalve flaps open and allow fluid to enter
• High permeability allows entrance of
– Tissue fluid and protein molecules
– Bacteria, viruses, and cancer cells
9. Distribution and Features of Lymphatic Capillaries
Figure 21.1
Lymphatic system
Lymph duct
Lymph trunk
Lymph node
Lymphatic
capillary
Blood
capillaries
Lymphatic
collecting
vessels, with
valves
(a) Structural relationship between a capillary
bed of the blood vascular system and
lymphatic capillaries
Heart
Arterial systemVenous system
Filaments anchored
to connective tissue
Fibroblast in loose
connective tissue
Endothelial cell
Flaplike minivalve
(b) Lymphatic capillaries are blind-ended tubes in which
adjacent endothelial cells overlap each other,
forming flaplike minivalves.
Tissue
fluid
Tissue cell Blood
capillaries
Lymphatic
capillaries
10. Lymphatic Collecting Vessels
• Accompany blood vessels
• Composed of the same three tunics as blood vessels
• Contain more valves than veins do
– Helps direct the flow of blood
• Lymph propelled by
– Skeletal muscles bulging
– Nearby arteries pulsing
– Tunica media of the lymph vessels
• Lymph flow is unaided by heartbeat
11. Lymph Nodes
• Cleanse the lymph of pathogens
• Human body contains around 500
• Superficial lymph nodes located in
– Cervical, axillary, and inguinal regions
• Deep nodes are
– Tracheobronchial, aortic, and iliac lymph nodes
12. General Distribution of Lymphatic Collecting Vessels and
Regional Lymph Nodes
Figure 21.2
Cervical
nodes
Entrance of
right lymphatic
duct into vein
Internal
jugular vein
Entrance of
thoracic duct
into vein
Thoracic
duct
Cisterna
chyli
Lymphatic
collecting
vessels
Axillary
nodes
Aorta
Inguinal
nodes
Regional
lymph
nodes
Drained by the right
lymphatic duct
Drained by the
thoracic duct
14. Microscopic Anatomy of a Lymph Node
Figure 21.3a
Afferent
lymphatic
vessels
Efferent lymphatic
vessels
Capsule
Trabeculae
Hilum
Cortex
Lymphoid follicle
Germinal center
Subcapsular sinus
Medulla
Medullary cord
Medullary sinus
(a) Longitudinal view of the internal structure
of a lymph node and associated lymphatics
15. Microscopic Anatomy of a Lymph Node
Figure 21.3b
Follicles
Trabecula
Subcapsular
sinus
Capsule
Medullary
cords
Medullary
sinuses
(b) Photomicrograph of part of a lymph node (14X)
16. Microscopic Anatomy of a Lymph Node
Figure 21.3c
(c) Reticular tissue within the medullary sinus (540X)
Macrophage
Medullary
sinus
Reticular
fiber
Lymphocytes
Reticular cells
on reticular
fibers
17. Lymph Trunks
• Lymphatic collecting vessels converge
• Five major lymph trunks
– Lumbar trunks
• Receives lymph from lower limbs
– Intestinal trunk
• Receives chyle from digestive organs
– Bronchomediastinal trunks
• Collects lymph from thoracic viscera
18. Lymph Trunks
• Five major lymph trunks (continued)
– Subclavian trunks
• Receive lymph from upper limbs and thoracic wall
– Jugular trunks
• Drain lymph from the head and neck
19. The Lymphatic Trunks
Figure 21.4a
Left jugular trunk
Internal jugular veins
Left subclavian trunk
Left subclavian vein
Esophagus
Trachea
Ribs
Left lumbar trunk
Left broncho-
mediastinal trunk
Entrance of thoracic
duct into vein
Thoracic duct
Hemiazygos vein
Intestinal trunk
Inferior vena cava
Right jugular trunk
Right lymphatic duct
Right subclavian
trunk
Right subclavian vein
Right broncho-
mediastinal trunk
Brachiocephalic veins
Superior vena cava
Azygos vein
Cisterna chyli
Right lumbar trunk
(a) Major lymphatic trunks and ducts in relation to veins
and surrounding structures, anterior view
20. The Lymphatic Trunks
Figure 21.4b
(b) Thoracic duct (colored green)
along the posterior thoracic wall
Azygos vein
on vertebral
bodies
Thoracic duct Aorta
21. Lymph Ducts
• Cisterna chyli
– Located at the union of lumbar and intestinal trunks
• Thoracic duct
– Ascends along vertebral bodies
– Empties into venous circulation
• Junction of left internal jugular and left subclavian veins
• Drains three quarters of the body
22. Right Lymphatic Duct
• Empties into right
internal jugular and
subclavian veins
Internal jugular veinsRight jugular trunk
Right lymphatic duct
Right subclavian
trunk
Right subclavian vein
Right broncho-
mediastinal trunk
Brachiocephalic veins
Superior vena cava
Azygos vein
Cisterna chyli
Right lumbar trunk
23. The Immune System
• Recognizes specific foreign molecules
• Destroys pathogens effectively
• Key cells—lymphocytes
• Also includes lymphoid tissue and lymphoid organs
• Lymphoid organs
– Lymph nodes, spleen, thymus, tonsils, aggregated
lymphoid nodules, and appendix
24. Lymphocytes
• Infectious organisms attacked by inflammatory
response
– Macrophages, then lymphocytes
• Are effective fighters of infectious organisms
– Each lymphocyte recognizes a specific foreign
molecule
• Antigens are any molecules inducing a response from a
lymphocyte
25. Lymphocytes
• B lymphocytes and T lymphocytes are the two main
classes of lymphocytes
• Cytotoxic T lymphocytes
– Attack foreign cells directly
• Binds to antigen-bearing cells
• Perforates cell membrane
• Signals cell to undergo apoptosis
• Destroy virus infected cells and some cancer cells
26. Lymphocytes
• B lymphocytes
– Become plasma cells
– Secrete antibodies
• Mark cells for destruction by macrophages
– Respond primarily to bacteria and bacterial toxins
27. Lymphocyte Function
Figure 21.5
T lymphocyte binds to
target cell, secretes proteins
that lyse the cell’s membrane,
and signals the cell to die.
B lymphocyte gives rise
to plasma cell, which
secretes antibodies.
Antibodies bind to
antigens on bacteria,
marking the bacteria for
destruction.
Antibody-coated
bacteria are avidly
phagocytized.
T lymphocyte detaches
from target cell.
Target
cell dies by
apoptosis.
T lymphocyte
Target cell,
bearing antigen Dead target cell
Antigen
(a) Action of cytotoxic T lymphocyte
(b) Differentiation and activity of B lymphocyte
B lymphocyte Plasma cell
Macrophage
Surface antigenAntibodies Bacterium
1 2 3
1 2 3
28. Lymphocyte Activation
• Lymphocytes originate in bone marrow
• Some travel to the thymus gland
– T lymphocytes
• Some stay in bone marrow
– B lymphocytes
• Able to recognize a unique antigen
– Gain immunocompetence
• Travels through blood stream
– Meets and binds to a specific antigen
30. Lymphocyte Activation
• Both T and B lymphocytes produce clones of
– Effector lymphocytes
• Respond immediately, then die
– Memory cells
• Wait until the body encounters the antigen again
• Basis of acquired immunity
• Prevent subsequent infections of the same illness
31. Lymphocyte Activation
Figure 21.6
Red bone
marrow
Bone
marrow
Immature
lymphocytes
Red bone marrow: site of
lymphocyte origin
Secondary lymphoid organs:
site of antigen encounter, and
activation to become effector
and memory B or T cells
Primary lymphoid organs:
site of development of immuno-
competence as B or T cells
Lymphocytes destined to become T cells
migrate (in blood) to the thymus and develop
immunocompetence there. B cells develop
immunocompetence in red bone marrow.
Immunocompetent but still
naive lymphocytes leave the
thymus and bone marrow. They
“seed” the lymph nodes, spleen,
and other lymphoid tissues where
they encounter their antigen.
Antigen-activated immuno-
competent lymphocytes
(effector cells and memory
cells) circulate continuously in
the bloodstream and lymph and
throughout the lymphoid
organs of the body.
1
2
3
Thymus
Lymph
nodes, spleen, and other
lymphoid tissues
32. Lymphoid Tissue
• Most important tissue of the immune system
• Two general locations
– Mucous membranes of
• Digestive, urinary, respiratory, and reproductive
tracts
– Mucosa-associated lymphoid tissue (MALT)
• Lymphoid organs (except thymus)
35. Lymphoid Organs
• Designed to gather and destroy infectious microorganisms and to
store lymphocytes
Figure 21.8
Tonsils (in pharyngeal
region)
Thymus (in thorax; most
active during youth)
Spleen (curves around
left side of stomach)
Aggregated lymphoid
nodule (in intestine)
Appendix
36. Thymus
• Immature lymphocytes develop into T lymphocytes
• Secretes thymic hormones
• Most active in childhood
• Functional tissue atrophies with age
• Composed of cortex and medulla
– Medulla contains Hassall’s corpuscles (thymic corpuscles)
• Differs from other lymphoid organs
– Functions strictly in lymphocyte maturation
– Arises from epithelial tissue
38. Lymph Nodes
• Function
– Lymph percolates through lymph sinuses
– Most antigenic challenges occur in lymph nodes
– Antigens destroyed and activate B and T
lymphocytes
39. Spleen
• Largest lymphoid organ
• Two main blood-cleansing functions
– Removal of blood-borne antigens
– Removal and destruction of old or defective blood cells
• Site of hematopoiesis in the fetus
40. Spleen
• Destruction of antigens
• Site of B cell maturation into plasma cells
• Phagocytosis of bacteria and worn-out RBCs, WBCs
and platelets
• Storage of platelets
41. Spleen
• White pulp
– Thick sleeves of lymphoid tissue
– Blood-borne antigens are destroyed as they activate the
immune response
– Provides the immune function of the spleen
• Red pulp
– Surrounds white pulp
– Composed of
• Venous sinuses
• Splenic cords
• Responsible for disposing of worn out RBCs
42. Spleen
Figure 21.10a, b
Splenic artery
Splenic vein
Hilum
(a) Diagram of the spleen,
anterior view
Arterioles
and
capillaries
Capsule
Trabecula
Venous sinuses
Red pulp
Splenic cords
White pulp
Central artery
Splenic artery
Splenic vein
(b) Diagram of spleen histology
43. Spleen
Figure 21.10c, d
(c) Photograph of the spleen in its normal
position in the abdominal cavity,
anterior view
Diaphragm
Spleen
Adrenal
gland
Splenic
artery
Pancreas
Left
kidney
(d) Photomicrograph of spleen tissue (7).
The white pulp, a lymphoid tissue with many
lymphocytes, is surrounded by red pulp
containing abundant erythrocytes.
Capsule
White pulp
Red pulp
44. Tonsils
• Simplest lymphoid organs
• Four groups of tonsils
– Palatine, lingual, pharyngeal, and tubal tonsils
• Arranged in a ring to gather and remove pathogens
• Underlying lamina propria consists of MALT
46. Aggregated Lymphoid Nodules & Appendix
• MALT—abundant in walls of intestines
• Fight invading bacteria
• Generate a wide variety of memory lymphocytes
– Aggregated lymphoid nodules (Peyer’s patches)
• Located in the distal part of the small intestine
– Appendix—tubular offshoot of the cecum
47. Smooth muscle in
the intestinal wall
Aggregated
lymphoid nodules
(Peyer’s patch)
Aggregated Lymphoid Nodule
Figure 21.12
48. Disorders of the Lymphatic
and Immune Systems
• Chylothorax
– Leakage of fatty lymph into the thorax
• Lymphangitis
– Inflammation of a lymph vessel
• Mononucleosis
– Viral disease caused by Epstein-Barr virus
– Attacks B lymphocytes
49. Disorders of the Lymphatic
and Immune Systems
• Hodgkin’s disease
– Malignancy of lymph nodes
• Non-Hodgkin’s lymphoma
– Uncontrolled multiplication and metastasis of
undifferentiated lymphocytes
50. The Lymphatic and
Immune Systems Throughout Life
• Lymphatic vessels and lymph nodes
– Develop from lymphatic sacs
• Thymus originates as an outgrowth of the endoderm
• Spleen, lymph nodes, and MALT
– Arise from mesodermal mesenchyme