This document discusses the structure and function of the cardiovascular system. It describes the different types of blood vessels including arteries, veins, and capillaries. It explains the layers of blood vessels and how blood flows from the heart through the arteries, capillaries and veins before returning to the heart. Key concepts covered include blood pressure, resistance, cardiac output, hormones that regulate blood pressure, and normal blood pressure readings.
Rheumatic Fever (Basics & Updates)
BY
Dr. Al Hussein Ragab Zaky
Luxor International Hospital,EGYPT
Tel: 00201113033672-00201012727282
Facebook : Al Hussein Ragab
crème de la crème basics to understand electrocardiographic analysis in an easy & simple way with some specifications to its use in Emergency medicine/clinical toxicology practice.
Rheumatic Fever (Basics & Updates)
BY
Dr. Al Hussein Ragab Zaky
Luxor International Hospital,EGYPT
Tel: 00201113033672-00201012727282
Facebook : Al Hussein Ragab
crème de la crème basics to understand electrocardiographic analysis in an easy & simple way with some specifications to its use in Emergency medicine/clinical toxicology practice.
Brief explanation of Junctional arrhythmia and Ventricular Arrhythmia. Slide 15, 16 and 18 are animations but cannot be viewed through the slide. Mail me if you need the animation or visit the website on the reference (number 7) and choose the animation according to your preference.
ECG Rhythm Interpretation
ST Elevation and non-ST Elevation MIs
ECG Changes
ECG Changes & the Evolving MI
Left Ventricular Hypertrophy
Normal Impulse Conduction
Bundle Branch Blocks
Brief explanation of Junctional arrhythmia and Ventricular Arrhythmia. Slide 15, 16 and 18 are animations but cannot be viewed through the slide. Mail me if you need the animation or visit the website on the reference (number 7) and choose the animation according to your preference.
ECG Rhythm Interpretation
ST Elevation and non-ST Elevation MIs
ECG Changes
ECG Changes & the Evolving MI
Left Ventricular Hypertrophy
Normal Impulse Conduction
Bundle Branch Blocks
Tunica Interna – innermost endothelium of simple squamous epithelium + basement membrane
Arteries – have an “internal elastic lamina” of elastic CT to allow for expansion under pressure
Veins – may have “valves” (folds of endothelium + CT) to prevent backflow of blood due to low pressure Microscopic, very thin-walled vessels comprised of endothelium with basement membrane; allows for filtration and reabsorption Found in all tissues of the body except for those that are “avascular” Usually form branching networks (“capillary beds”) within tissues for increased surface area blood flow into capillaries may be regulated by “pre- capillary sphincters” may have a central or “thoroughfare” channel that provides direct connection between “metarteriole” (terminal end of arteriole) & venule
The circulatory system transports fluids throughout the body;
it consists of the cardiovascular and lymphatic systems.
The heart and blood vessels make up the blood transportation network, the cardiovascular system.
Through this system, the heart pumps blood through the body’s vast system of blood vessels.
The blood carries nutrients, oxygen, and waste products to and from the cells.
VASCULAR CIRCUITS
The heart consists of two muscular pumps dividing the circulation into two components:
pulmonary circulations
systemic circulations or circuit
Pulmonary Circulation
Rt ventricle propels low O2 blood into the lungs via the pulmonary arteries.
CO2 is exchanged for O2 in the capillaries of the lungs.
Then the O2 -rich blood is returned via the pulmonary veins to the Lft atrium.
This circuit, from the right ventricle through the lungs to the left atrium, is the pulmonary circulation.
Systemic Circulation
Left ventricle propels the O2 -rich blood through systemic arteries (the aorta and its branches),
exchanging O2 and nutrients for CO2 in the remainder of the body’s capillaries.
Low- O2 blood returns to right atrium via systemic veins (tributaries of the superior and inferior vena cava).
This circuit, from left ventricle to right atrium, is the systemic circulation.
The cardiovascular system is transport system of body
It comprises blood, heart and blood vessels.
The system supplies nutrients to and remove waste products from various tissue of body.
The conveying media is liquid in form of blood which flows in close tubular system.
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
This document is designed as an introductory to medical students,nursing students,midwives or other healthcare trainees to improve their understanding about how health system in Sri Lanka cares children health.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Health Education on prevention of hypertensionRadhika kulvi
Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The
ICH Guidelines for Pharmacovigilance.pdfNEHA GUPTA
The "ICH Guidelines for Pharmacovigilance" PDF provides a comprehensive overview of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines related to pharmacovigilance. These guidelines aim to ensure that drugs are safe and effective for patients by monitoring and assessing adverse effects, ensuring proper reporting systems, and improving risk management practices. The document is essential for professionals in the pharmaceutical industry, regulatory authorities, and healthcare providers, offering detailed procedures and standards for pharmacovigilance activities to enhance drug safety and protect public health.
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Guillermo Rivera
This conference will delve into the intricate intersections between mental health, legal frameworks, and the prison system in Bolivia. It aims to provide a comprehensive overview of the current challenges faced by mental health professionals working within the legislative and correctional landscapes. Topics of discussion will include the prevalence and impact of mental health issues among the incarcerated population, the effectiveness of existing mental health policies and legislation, and potential reforms to enhance the mental health support system within prisons.
TOP AND BEST GLUTE BUILDER A 606 | Fitking FitnessFitking Fitness
"Feature:
• Intelligent Ergonomically Design Glute Builder Is A Must Have For Those Looking To Target Their Gluteal Muscles And Hamstrings With Precision.
• The Ability To Adjust The Starting Position, This Machine Allows For A More Targeted Workout That Is Tailored To Your Specific Needs.
• Spacious And Supportive Cushioned Seat Provide Added Comfort And Stability During Your Workout."
Get more information visit on:- www.fitking.in
Our mail I.D:-care@fitking.in, fitking.in@gmail.com
Call us at :- 9958880790, 9870336406, 8800695917
2. Types of Blood Vessels
Arteries - vessels that transport blood
away from the heart
Veins - return blood back to the heart
Capillaries - microscopic blood
vessels that allow exchanges
between blood and tissues
3. Structure of a blood vessel
Tunica externa (adventitia) - outermost layer
made of loose connective tissue. Serves to
anchor, protect and prevent overstretching
Tunica media - middle layer composed of
smooth muscle; functions in dilation and
constriction of blood vessels
Tunica interna(intima) - innermost layer made
of endothelium (s.squamous epithelium)
4.
5.
6.
7.
8. Blood flow through tissues
From the heart blood flows into
Aorta
Arteries
Arterioles
Capillaries
Venules
Veins
Superior/ Inferior Vena Cava
Back to the heart
11. Capillaries
Microscopic vessels that connect
arterioles and venules
Walls consist of a single layer of simple
squamous epithelial cells that allow the
exchange of gases
Precapillary sphincters regulate blood
flow
Continuous/Fenestrated capillaries
12. Veins
Venules merge to form veins
Have 3 distinct layers; thinner walled
than arteries due to thin tunica interna
and media
Large lumens and posses valves
Varicose veins
Blood reservoir
13. Systemic Circulation
The aorta and its major branches
Arterial supply to neck and head
Arterial supply to upper extremities
Arterial supply to thorax
Arterial supply to abdomen
Arterial supply to pelvic region and
lower extremities
14. Systemic Veins
Venous drainage of the head and neck
Major tributaries of the inferior vena
cava
Venous drainage of the upper
extremities
Venous drainage of the lower
extremities
15. Hepatic Portal System
Routes blood from the stomach, spleen,
pancreas, small and large intestines to
the liver
Blood from these structures all drain
into the hepatic portal vein, then into the
liver
Blood is returned to the inferior vena
cava via the hepatic vein
16. Fetal Circulation
Placenta - site where exchange of
materials between fetus and mother occur
Umbilical arteries (2) - carry fetal blood
high in CO2 / low in O2 to the placenta
Umbilical vein - returns oxygenated blood
from the placenta to the fetus
17. Fetal Circulation
Ductus venosus - allows blood to bypass
the liver
Foramen ovale - opening in interatrial
septum allowing blood to bypass the lungs
Blood flows from r.atrium ->l.atrium
Ductus arteriosus - vessel connecting
pulmonary artery to the aorta
18. 1. superior vena cava
2. inferior vena cava
3. pulmonary veins
4. pulmonary trunk (p. artery, p. aorta)
5. systemic aorta
A. Great Vessels
19.
20. Branches of systemic aorta
1. from ascending aorta, right and left
coronary artery
2. from aortic arch, brachiocephalic
artery
a. right subclavian artery
(1) r. axillary artery
(a) r. brachial artery
1. r. ulnar artery
2. r. radial artery
21.
22.
23. 3. superficial and deep
palmar arches
(anastomoses)
(b) deep brachial artery
(c) posterior circumflex
(2) r. vertebral artery
Branches of systemic aorta
24. b. right common carotid artery
(a) r. external carotid artery
(b) r. internal carotid artery
c. (cat, not human) left common
carotid artery
(a) l. external carotid artery
(b) l. internal carotid artery
Branches of systemic aorta
25.
26.
27. 3. from aortic arch (human, not cat),
left common carotid artery
a. l. external carotid artery
b. l. internal carotid artery
Branches of systemic aorta
28. 4. from aortic arch, left subclavian artery
(cat and human)
a. l. axillary artery
(1) l. brachial artery
(a) l. ulnar artery
(b) l. radial artery
(c) superficial and deep palmar
arches (anastomoses)
Branches of systemic aorta
29. (2) deep brachial artery
(3) posterior circumflex
b. l. vertebral artery
5. from descending thoracic aorta
a. paired bronchial arteries
b. paired intercostal arteries
Branches of systemic aorta
30. 6. from abdominal aorta
a. celiac trunk
(1) splenic artery
(2) l. gastric artery
(3) hepatic artery
Branches of systemic aorta
31.
32.
33. b. superior mesenteric artery
c. paired renal arteries
d. paired gonadal arteries
e. paired lumbar arteries
f. inferior mesenteric artery
Branches of systemic aorta
34.
35. g. right and left common iliac arteries
(1) internal iliacs
(2) external iliacs->femorals->
popliteal->tibial->dorsalis pedis->
plantar arches
Branches of systemic aorta
36.
37.
38. C. Major veins
A. coronary circulation: coronary sinus
B. pulmonary circulation: pulmonary
veins
C. hepatic portal circulation: hepatic
portal vein drains
1. inferior mesenteric which drains
splenic vein
2. superior mesenteric vein
41. E. Systemic Circulation:
1. superior vena cava drains
a. azygos system
b. right and left brachiocephalic veins
c. internal jugular and subclavian vein
d. external jugular and axillary
e. cephalic vein (superficial) and brachial
vein (deep) which drains
radial, ulnar, median cubital and basilic
veins
42.
43.
44. 2. inferior vena cava drains
a. hepatic vein
b. phrenic vein
c. paired renal veins
d. paired gonadal veins
45.
46. e. paired common iliac veins which drain
(1) paired internal iliac veins
(2) paired external iliac veins which drain
(a) femoral veins which drain
1. popliteal veins which drain
a peroneal vein
b anterior and posterior tibial veins
(b) great saphenous veins
51. Mechanisms of Exchange
Diffusion - major method used to
exchange substances such as O2,
CO2, glucose, and amino acids
Vesicular transport - endocytosis and
exocytosis of lipid-insoluble molecules
Bulk flow - involves filtration and
reabsorption
55. Blood Flow
Blood flow - is the amount of blood flowing
through a tissue in a given period of time
Velocity of blood flow is inversely related to
the diameter of the blood vessel
Blood flows most slowly in areas of greatest
width
56. Blood Pressure
Force that the blood exerts against the
walls of a blood vessels
Factors affecting BP include cardiac
output, blood volume, viscosity, resistance,
and the elasticity of the arteries
57. Cardiac Output
CO=Stroke volume X Heart Rate
Any factor that increases SV or HR will
increase blood pressure
58. Peripheral Resistance
Resistance to blood flow due to the force of
friction between vessel wall and blood
Resistance affected by blood viscosity,
vessel length and vessel radius
59. Sources affecting Resistance
Blood viscosity- how thick or thin the blood
is. Measured by hematocrit.
Vessel length- longer the vessel, the
greater the resistance, the greater the BP
Vessel radius- smaller the vessel the
greater the resistance
60. Blood Volume
↓ Blood volume , ↓ Blood pressure
↑ Blood volume, ↑Blood pressure
Blood volume & blood pressure monitored
by the cardiovascular center in the medulla
(ANS), baroreceptors and chemoreceptors
and by hormonal regulation
61. Hormonal Regulation
of Blood Pressure
Renin- angiotensin pathway
Angiotensin II - powerful vasoconstrictor
thus raising resistance
Stimulates secretion of aldosterone from the
adrenal gland promoting sodium retention
ADH - antidiuretic hormone from the pituitary
causing the kidneys to reabsorb more water
62. Hormone lowering BP
ANP - atrial natriutic peptide
released by atrial cells promoting the
loss of salt and water in the urine ,
thus ↓ blood volume and causing
vasodilation which then ↓ blood
pressure
PTH - parathyroid hormone causes
vasodilation
63. Endothelin = potent vasoconstrictor
responds to low blood flow
NO (nitrous oxide) = powerful
vasodilator; balances endothelin and
dilates vessels in response to high
blood flow.
64. Normal Blood Pressure
Newborn = 90/55 mm Hg
Adults = 120/80 mm Hg
Old Age = 150/90
Systolic Pressure = peak pressure during
systole
Diastolic pressure = lowest pressure during
diastole (filling of ventricles)