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Unit 5Unit 5
Anatomy andAnatomy and
PhysiologyPhysiology
CellsCells
Aim: To introduce the fundamentals ofAim: To introduce the fundamentals of
anatomy and physiology and cell function.anatomy and physiology and cell function.
Learning Intentions:
• To secure knowledge by being able to
identify the component parts of a cell.
• To further develop our knowledge by
describing the functions of the main cell
components.
• To show excellence by creating an
annotated display which explains the
structure and function of cells.
The human body is made upThe human body is made up
of:of:
• CellsCells
• TissuesTissues
• OrgansOrgans
• SystemsSystems
What is a cell?What is a cell?
• The “building block” of all living
things.
• All living things made up of 1 or
more cells
• Organised in groups each of which
have specific functions
Cells - the factsCells - the facts
• The human body is made up of millions ofThe human body is made up of millions of
tiny cellstiny cells
• These can only be seen under aThese can only be seen under a
microscopemicroscope
• They appear in many different shapes andThey appear in many different shapes and
sizes and have different functionssizes and have different functions
• Each cell has a nucleus which contains theEach cell has a nucleus which contains the
genetic coding called DNAgenetic coding called DNA
• Cells cannot function by themselvesCells cannot function by themselves
A Human CellA Human Cell
What is?What is?
• DNA (Deoxyribonucleic acid)
The chemical containing the genetic
code
• CHROMOSOME
A thread shaped body consisting of
DNA
NucleusNucleus
• The largest organelle.
• Cell survival and reproduction
happens here
• Contains DNA, the chromosomes
and proteins and the chromatin
Nuclear EnvelopeNuclear Envelope
• a physical barrier (membrane)
separating the contents of the
nucleus from the surrounding
cytoplasm
Endoplasmic reticulumEndoplasmic reticulum
• is concerned with the manufacture
and transportation of materials in the
cell.
• Rough ER - are important in the
production and transportation of
proteins.
• Smooth - creates and stores steroids
RibosomesRibosomes
• Produce the protein in a cell.
CytoplasmCytoplasm
• This is the fluid that fills the cell.
• The cells organelles are suspended in
the cytoplasm.
MitochondriaMitochondria
• Mitochondria are know as the
powerhouses of the cell.
• They take in nutrients, break them
down and creates energy for the cell
• This process is known as cellular
respiration
LysosomeLysosome
• Lysosomes hold enzymes that were
created by the cell.
• The purpose of the lysosome is to
digest things.
Golgi ComplexGolgi Complex
• Is a packaging organelle.
• It gathers simple molecules and
combines them to make molecules
that are more complex.
• It then takes those big molecules,
packages them in vesicles, and
either stores them for later use or
sends them out of the cell.
The Cell MembraneThe Cell Membrane
L.O understand theL.O understand the
organisation of the humanorganisation of the human
bodybody
Cell organelles “2”Cell organelles “2”
Learning Intentions:
To secure knowledge by being able to identify the
component parts of a cell.
To further develop our knowledge by describing the
functions of the main cell components.
To show excellence by building a cell membrane
model
Why do cells need membranes?Why do cells need membranes?
• Control entry and exit of substances
• Contain the cell contents and organelles;
compartmentalise individual cell
processes
• Communication with external
environment
• Site of chemical reactions
• Allows cell to change shape
• Transport and packaging within a cell
What are cell membranes madeWhat are cell membranes made
of?of?
• Most of the cell membrane is
impenetrable to water soluble
substances – it is composed of LIPIDS
• Water-soluble substance and other
molecules can pass into the cell through
passageways composed of PROTEINS
Fats and WaterFats and Water
• These two substances do not
mix
• Water is a polar molecule
(the oxygen end is slightly
negative and the hydrogen
end slightly positive)
• Fats are non-polar and do not
form hydrogen bonds with
water
• Fats are said to be
hydrophobic and lie on the
surface of the water to
reduce the surface area in
contact between the fat and
the water
Dietary lipids…Dietary lipids…
• The fats that make up the cell membrane are
different in structure to the dietary fats we have
come across before
• Dietary fats are composed of one glycerol backbone
with three fatty acids attached to it
• The fatty acids are non-polar and do not form
hydrogen bonds with water so they are insoluble
Lipids in the cell membraneLipids in the cell membrane
• These are
phospholipids
• They are composed of
a glycerol backbone,
two fatty acid chains
and a phosphate group
• The fatty acid chains
are non-polar
• The phosphate group
is polar
PhospholipidsPhospholipids
• They are usually drawn
like this
• The head (phosphate
group) is hydrophilic
• The tail (fatty acids) are
hydrophobic
And if you shake them
up in water?....
A MICELLE forms!
What happens if you place them
in water?....
So how are fats arranged in theSo how are fats arranged in the
cell membrane?...cell membrane?...
The Fluid Mosaic Model…The Fluid Mosaic Model…
• The phospholipid bilayer
is not a fixed structure
• Although the bilayer will
always remain arranged
in this configuration,
the individual
phospholipids are able
to move, hence why it is
also known as the fluid
mosaic model
• The phospholipids
rotate on their axis
• They can ‘swap' places
with the phospholipid
next to them
• They can occasionally
‘swap’ places with the
phospholipid directly
opposite them, though
this is rare
All of these movements increase the fluidity of the
membrane
What about the proteins in theWhat about the proteins in the
membrane?membrane?
• Some proteins are transmembrane – they span the
width of the phospholipid bilayer
• Others are fixed into the bilayer on one side only;
these are peripheral proteins
• The proteins have several different functions
Transmembrane ProteinsTransmembrane Proteins
• Water soluble substances pass
through proteins channels in the
bilayer
• These channels can be
permanent or temporary
• Gated channels allow selected
molecules through: conditions
within the cell determine
whether they are open or closed
• Other channels allow substances
to pass through freely in both
directions
• Some channels are active carrier
systems which use energy to
transport substances across
(e.g. the Sodium-Potassium
pump)
Peripheral proteinsPeripheral proteins
• Glycoproteins, found on the cells
surface, are protein molecules
with a carbohydrate group
attached
• These allow cells to
communicate with one another
• Individual groups of cells have
their own glycoproteins,
recognisable by the immune
system
• Proteins on the cells surface
also act as receivers for
incoming messages, such as
hormones
• Intracellular cell membranes
may also contain enzymes for
cell surface reactions
Practical taskPractical task
• On A3 paper label a cell leaving
space for the model of the cell
membrane and label it.

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Cells ppt

  • 1. Unit 5Unit 5 Anatomy andAnatomy and PhysiologyPhysiology CellsCells
  • 2. Aim: To introduce the fundamentals ofAim: To introduce the fundamentals of anatomy and physiology and cell function.anatomy and physiology and cell function. Learning Intentions: • To secure knowledge by being able to identify the component parts of a cell. • To further develop our knowledge by describing the functions of the main cell components. • To show excellence by creating an annotated display which explains the structure and function of cells.
  • 3. The human body is made upThe human body is made up of:of: • CellsCells • TissuesTissues • OrgansOrgans • SystemsSystems
  • 4. What is a cell?What is a cell? • The “building block” of all living things. • All living things made up of 1 or more cells • Organised in groups each of which have specific functions
  • 5. Cells - the factsCells - the facts • The human body is made up of millions ofThe human body is made up of millions of tiny cellstiny cells • These can only be seen under aThese can only be seen under a microscopemicroscope • They appear in many different shapes andThey appear in many different shapes and sizes and have different functionssizes and have different functions • Each cell has a nucleus which contains theEach cell has a nucleus which contains the genetic coding called DNAgenetic coding called DNA • Cells cannot function by themselvesCells cannot function by themselves
  • 6. A Human CellA Human Cell
  • 7.
  • 8. What is?What is? • DNA (Deoxyribonucleic acid) The chemical containing the genetic code • CHROMOSOME A thread shaped body consisting of DNA
  • 9. NucleusNucleus • The largest organelle. • Cell survival and reproduction happens here • Contains DNA, the chromosomes and proteins and the chromatin
  • 10. Nuclear EnvelopeNuclear Envelope • a physical barrier (membrane) separating the contents of the nucleus from the surrounding cytoplasm
  • 11. Endoplasmic reticulumEndoplasmic reticulum • is concerned with the manufacture and transportation of materials in the cell. • Rough ER - are important in the production and transportation of proteins. • Smooth - creates and stores steroids
  • 13. CytoplasmCytoplasm • This is the fluid that fills the cell. • The cells organelles are suspended in the cytoplasm.
  • 14. MitochondriaMitochondria • Mitochondria are know as the powerhouses of the cell. • They take in nutrients, break them down and creates energy for the cell • This process is known as cellular respiration
  • 15. LysosomeLysosome • Lysosomes hold enzymes that were created by the cell. • The purpose of the lysosome is to digest things.
  • 16. Golgi ComplexGolgi Complex • Is a packaging organelle. • It gathers simple molecules and combines them to make molecules that are more complex. • It then takes those big molecules, packages them in vesicles, and either stores them for later use or sends them out of the cell.
  • 17.
  • 18. The Cell MembraneThe Cell Membrane L.O understand theL.O understand the organisation of the humanorganisation of the human bodybody Cell organelles “2”Cell organelles “2” Learning Intentions: To secure knowledge by being able to identify the component parts of a cell. To further develop our knowledge by describing the functions of the main cell components. To show excellence by building a cell membrane model
  • 19. Why do cells need membranes?Why do cells need membranes? • Control entry and exit of substances • Contain the cell contents and organelles; compartmentalise individual cell processes • Communication with external environment • Site of chemical reactions • Allows cell to change shape • Transport and packaging within a cell
  • 20. What are cell membranes madeWhat are cell membranes made of?of? • Most of the cell membrane is impenetrable to water soluble substances – it is composed of LIPIDS • Water-soluble substance and other molecules can pass into the cell through passageways composed of PROTEINS
  • 21. Fats and WaterFats and Water • These two substances do not mix • Water is a polar molecule (the oxygen end is slightly negative and the hydrogen end slightly positive) • Fats are non-polar and do not form hydrogen bonds with water • Fats are said to be hydrophobic and lie on the surface of the water to reduce the surface area in contact between the fat and the water
  • 22. Dietary lipids…Dietary lipids… • The fats that make up the cell membrane are different in structure to the dietary fats we have come across before • Dietary fats are composed of one glycerol backbone with three fatty acids attached to it • The fatty acids are non-polar and do not form hydrogen bonds with water so they are insoluble
  • 23. Lipids in the cell membraneLipids in the cell membrane • These are phospholipids • They are composed of a glycerol backbone, two fatty acid chains and a phosphate group • The fatty acid chains are non-polar • The phosphate group is polar
  • 24. PhospholipidsPhospholipids • They are usually drawn like this • The head (phosphate group) is hydrophilic • The tail (fatty acids) are hydrophobic
  • 25. And if you shake them up in water?.... A MICELLE forms! What happens if you place them in water?....
  • 26. So how are fats arranged in theSo how are fats arranged in the cell membrane?...cell membrane?...
  • 27. The Fluid Mosaic Model…The Fluid Mosaic Model… • The phospholipid bilayer is not a fixed structure • Although the bilayer will always remain arranged in this configuration, the individual phospholipids are able to move, hence why it is also known as the fluid mosaic model • The phospholipids rotate on their axis • They can ‘swap' places with the phospholipid next to them • They can occasionally ‘swap’ places with the phospholipid directly opposite them, though this is rare All of these movements increase the fluidity of the membrane
  • 28. What about the proteins in theWhat about the proteins in the membrane?membrane? • Some proteins are transmembrane – they span the width of the phospholipid bilayer • Others are fixed into the bilayer on one side only; these are peripheral proteins • The proteins have several different functions
  • 29. Transmembrane ProteinsTransmembrane Proteins • Water soluble substances pass through proteins channels in the bilayer • These channels can be permanent or temporary • Gated channels allow selected molecules through: conditions within the cell determine whether they are open or closed • Other channels allow substances to pass through freely in both directions • Some channels are active carrier systems which use energy to transport substances across (e.g. the Sodium-Potassium pump)
  • 30. Peripheral proteinsPeripheral proteins • Glycoproteins, found on the cells surface, are protein molecules with a carbohydrate group attached • These allow cells to communicate with one another • Individual groups of cells have their own glycoproteins, recognisable by the immune system • Proteins on the cells surface also act as receivers for incoming messages, such as hormones • Intracellular cell membranes may also contain enzymes for cell surface reactions
  • 31. Practical taskPractical task • On A3 paper label a cell leaving space for the model of the cell membrane and label it.