3. Discovery of Cells
• Robert Hooke (1665)
• Observed sliver of cork
• Saw “row of empty boxes”
• Coined the term cell
4. Cell theory
• (1839)Theodor Schwann & Matthias Schleiden
“ all living things are made of cells”
• (1855) Rudolf Virchow
“Omnis cellula e cellula ” all cells arise from pre-existing
cells
5. Principles of Cell Theory
• All living things are made of cells
• Smallest living unit of structure and function of all organisms is
the cell
• All cells arise from preexisting cells
(this principle discarded the idea of
spontaneous generation)
8. Cells have high surface area to volume ratio
• This allows them to rely on oxygen and materials diffusing in to the
cell (and wastes diffusing out) in order to survive.
9. Characteristics of All Cells
• A surrounding membrane
• Protoplasm – cell contents in thick fluid
• Organelles – structures for cell function
• Control center with DNA
12. Prokaryotic Cells
• No membrane bound nucleus
• Nucleoid = region of DNA concentration
• Organelles not bound by membranes
13. Eukaryotic Cells
• Nucleus bound by membrane
• Include fungi, protists, plant, and animal cells
• Possess many organelles
Protozoan
14.
15. THE UNIVERSE INSIDE OUR CELLS
• Zoom into your own body to see the
different cells that make up your
heart, brain and bones.
• These trillions building block of
cells are communicating with each
other every moment of our lives.
• As the house is made by BRICKS.
20. CELL ORGANELLES
The cellular components are called the Cell Organelles.
These cell organelles are membrane-bound, present within the cells
and are distinct in their structures and functions.
They coordinate with their functions efficiently for the normal
functioning of the cell.
There are various organelles present within the cell and
are classified into three categories based on the presence or
absence of membrane.
https://youtu.be/JL19uv7NT7s?si=TzMAAkD
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21. TYPES OF CELL ORGANELLES
Organelles without membrane: The Cell wall, Ribosomes, Centrosome and
Cytoskeleton are without membrane-bound cell organelles.
Single membrane-bound organelles: Vacuole, Lysosome, Golgi Apparatus,
Endoplasmic Reticulum are single membrane-bound organelles present
only in a eukaryotic cell.
Double membrane-bound organelles: Mitochondria and chloroplast are
double membrane-bound organelles present only in a eukaryotic cell.
23. Movement Across the Plasma Membrane
• A few molecules move freely
• Water, Carbon dioxide, Ammonia, Oxygen
• Carrier proteins transport some molecules
• Proteins embedded in lipid bilayer
• Fluid mosaic model – describes fluid nature of a lipid bilayer with proteins
https://youtu.be/qBCVVszQQNs?si=HZwyiLzhjdggQpeV
24.
25. Membrane Proteins
1. Channels or transporters
• Move molecules in one direction
2. Receptors
• Recognize certain chemicals
27. CELL MEMBRANE FUNCTION
• Passive Transport
• Active Transport
• Endocytosis
(phagocytosis & pinocytosis)
• Exocytosis
28. Passive Transport
• No energy required
• Move due to gradient
• differences in concentration, pressure, charge
• Move to equalize gradient
• High moves toward low
29. Types of Passive Transport
1. Diffusion
2. Osmosis
3. Facilitated diffusion
31. Osmosis
• Special form of diffusion
• Fluid flows from lower solute concentration
• Often involves movement of water
• Into cell
• Out of cell
32. Solution Differences & Cells
• solvent + solute = solution
• Hypotonic
• Solutes in cell more than outside
• Outside solvent will flow into cell And cell will swell
• Isotonic
• Solutes equal inside & out of cell no transport
• Hypertonic
• Solutes greater outside cell
• Fluid will flow out and shrink
33.
34. Facilitated Diffusion
• Differentially permeable membrane
• Channels (are specific) help molecule or ions enter or leave the cell
• Channels usually are transport proteins
(aquaporins facilitate the movement of water)
• No energy is used
35. Process of Facilitated Transport
• Protein binds with molecule
• Shape of protein changes
• Molecule moves across membrane
37. Endocytosis
• Movement of large material
• Particles
• Organisms
• Large molecules
• Movement is into cells
• Types of endocytosis
• bulk-phase (nonspecific)
• receptor-mediated (specific)
38. Process of Endocytosis
• Plasma membrane surrounds material
• Edges of membrane meet
• Membranes fuse to form vesicle
48. Endoplasmic Reticulum
• Helps move substances within cells
• Network of interconnected membranes
• Two types
• Rough endoplasmic reticulum
• Smooth endoplasmic reticulum
49. Rough Endoplasmic Reticulum
• Ribosomes attached to surface
• Manufacture protiens
• Not all ribosomes attached to rough ER
• May modify proteins from ribosomes
52. Golgi Apparatus Function
1. Molecules come in vesicles
2. Vesicles fuse with Golgi membrane
3. Molecules may be modified by Golgi
53. Golgi Apparatus Function (Continued)
4. Molecules pinched-off in separate vesicle
5. Vesicle leaves Golgi apparatus
6. Vesicles may combine with plasma membrane to secrete contents
54.
55. Lysosomes
• Contain digestive enzymes
• Functions
• Aid in cell renewal
• Break down old cell parts
• Digests invaders
56. CELL ORGANELLES
1 NUCLEUS
2 GOLGI BODY
3 PLASMA MEMBRANE
4 CYTOPLASM
5 ENDOPLASMIC RETICULUM
6 MITOCHONDRIA
7 LYSOSOME
8 VACUOLES
9 RIBOSOMES
10 MICROBODIES
(a) PEROXIXOMES
(b) GLYOXYSOME
DISCOVERY
1 ROBERT BROWN(1831)
2 CAMEILLIO GOLGI
3 SCHWANN(1838)
4 STRASBURGER(1882)
5 PORTER(1943)AND NAMED
IN(1953)
6 ALTAMAN(1894)AND NAMED BY
BENDA(1897)
7 de DUVE(1955)
8 SPALLANZONI
9 ROBINSON AND BROWN (1953)
IN PLANT CELL AND PALADE(1955)
IN ANIMAL CELL
10 RHODIN(1954)
(a)de DUVE(1965)
(b)BRIEDENBACH(1967)
57.
58. Comparison between Plant cell and
Animal cell
PLANT CELL
Shape
Square or rectangular in shape
Size
40-100 micrometers
Cell wall
Present
Cell membrane
Present
Endoplasmic reticulum, Golgi
apparatus, Cytoplasm, ribosomes
Present
Lysosomes
Absent
ANIMAL CELL
Shape
Irregular or round in shape
Size
10-20 micrometers
Cell wall
Absent
Cell membrane
Present
Endoplasmic reticulum, Golgi
apparatus, Cytoplasm, ribosomes
Present
Lysosomes
Present
59. Contd…
Nucleus
Present and lies on one side of the
cell
Plastids
Present
Vacuoles
Few large or a single, centrally
positioned vacuole
Cilia
Absent
Mitochondria
Present but fewer in number
Centrioles and centrosomes
absent
Mode of Nutrition
Primarily autotrophic
Nucleus
Present and lies in the center of
the cell
Plastids
Absent
Vacuoles
usually small and numerous
Cilia
Present in most of the animal cells
Mitochondria
Present and are numerous
Centrioles and centrosomes
Present
Mode of nutrition
Heterotrophic