Peptic ulcer disease is caused by an imbalance between aggressive gastric factors like acid and pepsin and protective mucosal defenses. H. pylori infection plays a key role in most peptic ulcers by damaging the mucosal layer. Treatment involves eradicating H. pylori with triple therapy using a PPI and two antibiotics for 2 weeks, and continuing PPI therapy for an additional 2 weeks to aid ulcer healing. Adherence to the full treatment course is important for successful eradication.

1. Peptic Ulcer Disease Andrea M. Wilkins-Daly BSc.,PharmD October 2009

9. PEPTIC ULCER DISEASE

10. Duodenal Ulcer Duodenal Ulcer

11. DU in 65yo male

12. DU in 35 yo female

13. Duodenal ulcer

14. Pathophysiology