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PHARMACOTHERAPEUTICS-III
CASE PRESENTATION
NANDHA COLLEGE OF PHARMACY
RAJNANDINI SINGHA
IV Pharm D
CASE STUDY
ON
GERD
SUBJECTIVE
A 60 year old Male patient was
admitted in Perundarai medical
college hospital on 25/1/2018
with the complaints of
abdominal discomfort for 10 days.
HISTORY OF PRESENT ILLNESS
H/O Abdominal discomfort
H/O Difficulty in breathing
H/O skin allergy
H/O cough with expectoration
PAST HISTORY
K/C bronchial asthma before 3
days
PERSONAL HISTORY
Diet: Mixed.
GENERAL EXAMINATION
 Patient conscious,
oriented
 BP :160/70 mmHg
 PR :79 bpm
SYSTEMIC EXAMINATION
 CVS – S1S2 Heard
 RS - B/L AE+,B/L WHEEZ+
 CNS – NFND
 P/A - Soft
OBJECTIVE
INVESTIGATION CHART
NAME OF
INVESTIGATION
OBSERVED VALUE NORMAL VALUE
WBC 14.0x109/L 4.5-10.5×109/L
RBC 4.26x1012/L 3.8-5.9×1012/L
HAEMOGLOBIN 10.5g/dl 12-14g/dl
PLATELETS 173.0109/L 130-400109/L
L/M/G 2.5/1.5/11.0109/L
MCV 92.9 FL 80-100FL
HCT 40.2% 35-50%
MCH 27.6pg 27- 34pg
MCHC 29.7g/dl 32-36g/dl
ESR 32mm/hr 0-20mm/hr
BIOCHEMISTRY
RBS 67 mg/dl Up to 140 mg/dl
BLOOD UREA 30 mg/dl 10-40 mg/dl
SERUM CREATININE 1.0mg/dl 0.6-1.3 mg/dl
SERUM PHOSPHATE 3.5 mg/dl 2.5-4.5 mg/dl
URINE ANALYSIS
COLOUR PALE YELLOW
REACTION Acidic
ALBUMIN NIL
PROGRESS CHART

DATE TEMP (°F) B.P P.R R.R
25/1/18 98.4 110/80 80 20
26/1/18 98.4 110/80 75 22
27/1/18 98.8 100/80 84 20
28/1/18 98.6 140/60 82 20
29/1/18 98.4 110/80 78 22
30/1/18 99 140/80 82 20
31/1/18 98.5 120/80 80 20
1/1/18 98.7 140/80 85 22
2/1/18 98.4 120/80 82 22
OTHER INVESTIGATION
X-RAY –Increased BVM
(bronchovascular marking)
ASSESMENT
FINAL DIAGNOSIS:
 Bronchial Asthma
 GERD( Gastroesophageal reflux
disease)
DRUG CHART
DRUG GENERIC NAME DOSE ROUTE FREQ 3 4 5 6 7
Inj.genta Gentamycin 1mg IV 1-0-1 √ √ √ √ √
INJ .RANTAC Ranitidine 2ml IM 1-0-0 √ √ √ √ √
T.CPM Chlorphenaramin
e
10mg PO 1-0-1 √ √ √ √ √
T. Dolo Paracetamol 650mg PO 1-1-1 √ √ √ √ √
Inj. Deri Theophylline+Eto
phylline
2ml IV 1-0-1 √ √ √ √ √
T.celin Vitamin C 40mg PO 1-0-0 √ √ √ √ √
SYRUP.
Rantac
ranitidine 15mg PO 1-0-1 √ √ √ √ √
Liquid paraffin Liquid paraffin 10ml topical 0-0-1 √ √ √ √ √
DRUG GENERIC NAME DOSE ROUTE FREQ 3 4 5 6 7
BVM
OINTMENT
Betamethasone
valarate
0.1% 1-1-1 topical √ √ √ √ √
SYRUP.
REXCOF
Dextromethophan
and
chlorpheniramine
maleate
100ml 1-0-1 PO √ √
SALBUTAMOL
NEB
SUBUTAMOL 1-1-1 NASAL √ √ √ √ √
DISCHARGE SUMMARY
The patient was discharged on 7/02/18
DISCHARGE ADVICE
T.PARACETAMOL(1-1-1) 650mg
T.CPM(1-0-1)10mg
SYRUP.RANTAC(1-1-1)10ml
T.CELIN(VITAMIN C) (1-0-0)500mg
Liquid paraffin(1-0-1)
BVM OINTMENT(1-0-1)
PLAN
PATIENT COUNSELLING:
DRUG RELATED DISEASE RELATED LIFE STYLE
MODIFICATION
•Take SYRUP Rantac
before 30mins of food
•LIQUIID PARAFFIN and
BVM OINTMENT should
be apply on dry skin.
• Advice the patient not
to skip meals.
•Avoid stress and NSAIDS
• Elevate the head on the
bed.
COPD:
On coughing mouth
should be closed.
Avoid dust, allergen,
alcohol, smoking.
•Avoid choclate, coffee,
soda, alcoholic drinks.
• Avoid Citrus fruits and
juices of tomato.
•Advice the patient to eat
boil food for 2-3 weeks.
•Green vegetables should
be taken to regenerate
the lining of stomach.
S.N
O
ASSESMENT PLAN
1. Chlorpheniramine + food
Alcohol can increase the CNS Side
effect such as drowsiness, dizziness
..
MANAGEMENT: To avoid
consumption of alcohol , hazardous
activities require complete
alterness
,mental alertness.
Syrup Ranitidine should administered
30mins before food.
3. T.CPM AND SYRUP .Rexcof
Side effect - sleepiness
Do not prescribe in the morning
MONITORING PARAMTER:
 pH Monitoring for GERD
Increased acid exposure time.
PHARMACIST INTERVENTION:
 Antacid should be recommended in the prescription.
 Suggesting to Reduce the adminstration of PARACETAMOL to
reduce toxicity.
 Proton pump inhibitor is recommended to be add in the
prescription.
THANK YOU

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Gerd Case Study and Pharmacotherapy

  • 1. PHARMACOTHERAPEUTICS-III CASE PRESENTATION NANDHA COLLEGE OF PHARMACY RAJNANDINI SINGHA IV Pharm D
  • 3. SUBJECTIVE A 60 year old Male patient was admitted in Perundarai medical college hospital on 25/1/2018 with the complaints of abdominal discomfort for 10 days.
  • 4. HISTORY OF PRESENT ILLNESS H/O Abdominal discomfort H/O Difficulty in breathing H/O skin allergy H/O cough with expectoration
  • 5. PAST HISTORY K/C bronchial asthma before 3 days
  • 7. GENERAL EXAMINATION  Patient conscious, oriented  BP :160/70 mmHg  PR :79 bpm
  • 8. SYSTEMIC EXAMINATION  CVS – S1S2 Heard  RS - B/L AE+,B/L WHEEZ+  CNS – NFND  P/A - Soft
  • 9. OBJECTIVE INVESTIGATION CHART NAME OF INVESTIGATION OBSERVED VALUE NORMAL VALUE WBC 14.0x109/L 4.5-10.5×109/L RBC 4.26x1012/L 3.8-5.9×1012/L HAEMOGLOBIN 10.5g/dl 12-14g/dl PLATELETS 173.0109/L 130-400109/L L/M/G 2.5/1.5/11.0109/L MCV 92.9 FL 80-100FL HCT 40.2% 35-50% MCH 27.6pg 27- 34pg
  • 10. MCHC 29.7g/dl 32-36g/dl ESR 32mm/hr 0-20mm/hr BIOCHEMISTRY RBS 67 mg/dl Up to 140 mg/dl BLOOD UREA 30 mg/dl 10-40 mg/dl SERUM CREATININE 1.0mg/dl 0.6-1.3 mg/dl SERUM PHOSPHATE 3.5 mg/dl 2.5-4.5 mg/dl URINE ANALYSIS COLOUR PALE YELLOW REACTION Acidic ALBUMIN NIL
  • 11. PROGRESS CHART  DATE TEMP (°F) B.P P.R R.R 25/1/18 98.4 110/80 80 20 26/1/18 98.4 110/80 75 22 27/1/18 98.8 100/80 84 20 28/1/18 98.6 140/60 82 20 29/1/18 98.4 110/80 78 22 30/1/18 99 140/80 82 20 31/1/18 98.5 120/80 80 20 1/1/18 98.7 140/80 85 22 2/1/18 98.4 120/80 82 22
  • 12. OTHER INVESTIGATION X-RAY –Increased BVM (bronchovascular marking)
  • 13.
  • 14. ASSESMENT FINAL DIAGNOSIS:  Bronchial Asthma  GERD( Gastroesophageal reflux disease)
  • 15. DRUG CHART DRUG GENERIC NAME DOSE ROUTE FREQ 3 4 5 6 7 Inj.genta Gentamycin 1mg IV 1-0-1 √ √ √ √ √ INJ .RANTAC Ranitidine 2ml IM 1-0-0 √ √ √ √ √ T.CPM Chlorphenaramin e 10mg PO 1-0-1 √ √ √ √ √ T. Dolo Paracetamol 650mg PO 1-1-1 √ √ √ √ √ Inj. Deri Theophylline+Eto phylline 2ml IV 1-0-1 √ √ √ √ √ T.celin Vitamin C 40mg PO 1-0-0 √ √ √ √ √ SYRUP. Rantac ranitidine 15mg PO 1-0-1 √ √ √ √ √ Liquid paraffin Liquid paraffin 10ml topical 0-0-1 √ √ √ √ √
  • 16. DRUG GENERIC NAME DOSE ROUTE FREQ 3 4 5 6 7 BVM OINTMENT Betamethasone valarate 0.1% 1-1-1 topical √ √ √ √ √ SYRUP. REXCOF Dextromethophan and chlorpheniramine maleate 100ml 1-0-1 PO √ √ SALBUTAMOL NEB SUBUTAMOL 1-1-1 NASAL √ √ √ √ √
  • 17. DISCHARGE SUMMARY The patient was discharged on 7/02/18 DISCHARGE ADVICE T.PARACETAMOL(1-1-1) 650mg T.CPM(1-0-1)10mg SYRUP.RANTAC(1-1-1)10ml T.CELIN(VITAMIN C) (1-0-0)500mg Liquid paraffin(1-0-1) BVM OINTMENT(1-0-1)
  • 18. PLAN
  • 19. PATIENT COUNSELLING: DRUG RELATED DISEASE RELATED LIFE STYLE MODIFICATION •Take SYRUP Rantac before 30mins of food •LIQUIID PARAFFIN and BVM OINTMENT should be apply on dry skin. • Advice the patient not to skip meals. •Avoid stress and NSAIDS • Elevate the head on the bed. COPD: On coughing mouth should be closed. Avoid dust, allergen, alcohol, smoking. •Avoid choclate, coffee, soda, alcoholic drinks. • Avoid Citrus fruits and juices of tomato. •Advice the patient to eat boil food for 2-3 weeks. •Green vegetables should be taken to regenerate the lining of stomach.
  • 20. S.N O ASSESMENT PLAN 1. Chlorpheniramine + food Alcohol can increase the CNS Side effect such as drowsiness, dizziness .. MANAGEMENT: To avoid consumption of alcohol , hazardous activities require complete alterness ,mental alertness. Syrup Ranitidine should administered 30mins before food. 3. T.CPM AND SYRUP .Rexcof Side effect - sleepiness Do not prescribe in the morning
  • 21. MONITORING PARAMTER:  pH Monitoring for GERD Increased acid exposure time.
  • 22. PHARMACIST INTERVENTION:  Antacid should be recommended in the prescription.  Suggesting to Reduce the adminstration of PARACETAMOL to reduce toxicity.  Proton pump inhibitor is recommended to be add in the prescription.