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BLOOD TYPES

An Example of Inheritance
with Multiple Alleles
Module 10 – Genetics
Essential Standard Bio.3.2.2
BLOOD TYPES
 The ABO   blood group is an example of a
  single gene that has multiple alleles in humans.
 Multiple Alleles = more than 2 forms of the
  gene.
 There are 3 possible alleles for this gene:
     A, B, and o.
 Remember   that each person only has 2 alleles.
 A and B are codominant, and o is recessive.
BLOOD TYPES

 A and B are 2 different molecules found
 on the outside of red blood cells.




           http://learn.genetics.utah.edu/content/begin/traits/blood/
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A

    Type B

   Type AB

    Type O
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A

    Type B

   Type AB

    Type O
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A

    Type B         B

   Type AB

    Type O
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A

    Type B         B

   Type AB       A and B

    Type O
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A

    Type B         B

   Type AB       A and B

    Type O        None
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A        AA or Ao

    Type B         B

   Type AB       A and B

    Type O        None
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A        AA or Ao

    Type B         B        BB or Bo

   Type AB       A and B

    Type O        None
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A        AA or Ao

    Type B         B        BB or Bo

   Type AB       A and B       AB

    Type O        None
BLOOD TYPE CHART

   Blood Type    Surface      Alleles
  (Phenotype)   Molecules   (Genotype)
    Type A         A        AA or Ao

    Type B         B        BB or Bo

   Type AB       A and B       AB

    Type O        None         oo
BLOOD TYPES
Doctors   need to determine blood type
 before a person can get a blood
 transfusion because the red blood
 cells of incompatible blood types
 could clump together, causing death.
BLOOD COMPATIBILITY CHART
Blood Type (Phenotype)

        Type A

        Type B

       Type AB

       Type O
BLOOD COMPATIBILITY CHART
                         Compatible Blood
Blood Type (Phenotype)
                       Types for Transfusions
        Type A

        Type B

       Type AB

       Type O
BLOOD COMPATIBILITY CHART
                         Compatible Blood
Blood Type (Phenotype)
                       Types for Transfusions
        Type A             Type A or Type O

        Type B

       Type AB

       Type O
BLOOD COMPATIBILITY CHART
                         Compatible Blood
Blood Type (Phenotype)
                       Types for Transfusions
        Type A             Type A or Type O

        Type B            Type B or Type O

       Type AB

       Type O
BLOOD COMPATIBILITY CHART
                         Compatible Blood
Blood Type (Phenotype)
                       Types for Transfusions
        Type A             Type A or Type O

        Type B            Type B or Type O
                       Type AB, Type A, Type B,
       Type AB                or Type O
                         (Universal Recipient)
       Type O
BLOOD COMPATIBILITY CHART
                         Compatible Blood
Blood Type (Phenotype)
                       Types for Transfusions
        Type A             Type A or Type O

        Type B            Type B or Type O
                       Type AB, Type A, Type B,
       Type AB                or Type O
                         (Universal Recipient)
                               Type O
       Type O
                          (Universal Donor)
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?




         A
Dad
         B
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A
Dad
         B
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A      A
Dad
         B
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB
Dad
         B
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB
Dad
         B      B
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB
Dad
         B     BB
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB            A
Dad
         B     BB
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB           A?
Dad
         B     BB
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB           A?
Dad
         B     BB            B
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB           A?
Dad
         B     BB           B?
EXAMPLE PROBLEM #1
   Mom has blood type B and Dad has blood type AB.
    What is the chance their child will have blood type
    B?

                     Mom
                B            ?

         A     AB           A?
                                        ½ chance of
Dad                                        type B
         B     BB           B?
EXAMPLE PROBLEM #2
   Mom has blood type A and her child has blood type
    B. Could the father have blood type O?
EXAMPLE PROBLEM #2
   Mom has blood type A and her child has blood type
    B. Could the father have blood type O?
    The answer is NO.
    The child had to have inherited the B
    allele from their real father;
    the type O man just has oo so he could
    not be the father.
EXAMPLE PROBLEM #2
   Mom has blood type A and her child has blood type
    B. Could the father have blood type O?
    The answer is NO.
    The child had to have inherited the B
    allele from their real father;
    the type O man just has oo so he could
    not be the father.

       This example comes from a true case
       in the 1940s involving the film star
       Charlie Chaplin.

                                   http://www.cosmomovieawards.com/actors/charlie_chaplin.html

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Blood Types

  • 1. BLOOD TYPES An Example of Inheritance with Multiple Alleles Module 10 – Genetics Essential Standard Bio.3.2.2
  • 2. BLOOD TYPES  The ABO blood group is an example of a single gene that has multiple alleles in humans.  Multiple Alleles = more than 2 forms of the gene.  There are 3 possible alleles for this gene:  A, B, and o.  Remember that each person only has 2 alleles.  A and B are codominant, and o is recessive.
  • 3. BLOOD TYPES  A and B are 2 different molecules found on the outside of red blood cells. http://learn.genetics.utah.edu/content/begin/traits/blood/
  • 4. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A Type B Type AB Type O
  • 5. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A Type B Type AB Type O
  • 6. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A Type B B Type AB Type O
  • 7. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A Type B B Type AB A and B Type O
  • 8. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A Type B B Type AB A and B Type O None
  • 9. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A AA or Ao Type B B Type AB A and B Type O None
  • 10. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A AA or Ao Type B B BB or Bo Type AB A and B Type O None
  • 11. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A AA or Ao Type B B BB or Bo Type AB A and B AB Type O None
  • 12. BLOOD TYPE CHART Blood Type Surface Alleles (Phenotype) Molecules (Genotype) Type A A AA or Ao Type B B BB or Bo Type AB A and B AB Type O None oo
  • 13. BLOOD TYPES Doctors need to determine blood type before a person can get a blood transfusion because the red blood cells of incompatible blood types could clump together, causing death.
  • 14. BLOOD COMPATIBILITY CHART Blood Type (Phenotype) Type A Type B Type AB Type O
  • 15. BLOOD COMPATIBILITY CHART Compatible Blood Blood Type (Phenotype) Types for Transfusions Type A Type B Type AB Type O
  • 16. BLOOD COMPATIBILITY CHART Compatible Blood Blood Type (Phenotype) Types for Transfusions Type A Type A or Type O Type B Type AB Type O
  • 17. BLOOD COMPATIBILITY CHART Compatible Blood Blood Type (Phenotype) Types for Transfusions Type A Type A or Type O Type B Type B or Type O Type AB Type O
  • 18. BLOOD COMPATIBILITY CHART Compatible Blood Blood Type (Phenotype) Types for Transfusions Type A Type A or Type O Type B Type B or Type O Type AB, Type A, Type B, Type AB or Type O (Universal Recipient) Type O
  • 19. BLOOD COMPATIBILITY CHART Compatible Blood Blood Type (Phenotype) Types for Transfusions Type A Type A or Type O Type B Type B or Type O Type AB, Type A, Type B, Type AB or Type O (Universal Recipient) Type O Type O (Universal Donor)
  • 20. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B?
  • 21. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? A Dad B
  • 22. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A Dad B
  • 23. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A A Dad B
  • 24. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB Dad B
  • 25. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB Dad B B
  • 26. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB Dad B BB
  • 27. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB A Dad B BB
  • 28. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB A? Dad B BB
  • 29. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB A? Dad B BB B
  • 30. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB A? Dad B BB B?
  • 31. EXAMPLE PROBLEM #1  Mom has blood type B and Dad has blood type AB. What is the chance their child will have blood type B? Mom B ? A AB A? ½ chance of Dad type B B BB B?
  • 32. EXAMPLE PROBLEM #2  Mom has blood type A and her child has blood type B. Could the father have blood type O?
  • 33. EXAMPLE PROBLEM #2  Mom has blood type A and her child has blood type B. Could the father have blood type O? The answer is NO. The child had to have inherited the B allele from their real father; the type O man just has oo so he could not be the father.
  • 34. EXAMPLE PROBLEM #2  Mom has blood type A and her child has blood type B. Could the father have blood type O? The answer is NO. The child had to have inherited the B allele from their real father; the type O man just has oo so he could not be the father. This example comes from a true case in the 1940s involving the film star Charlie Chaplin. http://www.cosmomovieawards.com/actors/charlie_chaplin.html