Blood has four main functions: carrying oxygen and carbon dioxide, removing waste, transporting nutrients, and fighting infections. It contains red blood cells, which carry oxygen and carbon dioxide using hemoglobin, an iron-rich protein. White blood cells help fight infection as part of the immune system. Platelets help blood clot to prevent excessive bleeding from injuries. Blood type is determined by antigens, and certain types cannot be mixed in transfusions. Diseases of the blood include anemias like sickle cell anemia and leukemias, in which too many white blood cells are produced. The lymphatic system carries lymph containing white blood cells and filters it through lymph nodes to fight infection. AIDS weakens this system by infect