This document discusses various urinary diversion procedures including continent pouches and orthotopic neobladders. It describes different types of pouches such as the Indiana pouch, Florida pouch, Penn pouch, Kock pouch, and T-pouch which are created using segments of the ileum, cecum or colon. The document outlines techniques for creating antirefluxing conduits and continent diversion mechanisms such as the use of an appendiceal tunnel or imbricated ileocecal valve. It also discusses postoperative care and complications of these urinary diversion procedures.
The surgical treatment of an injury or defect within the urethra's walls is known as urethroplasty. The three most frequent factors leading to urethral damage that needs to be repaired are trauma, iatrogenic injury, and infections. The gold standard treatment for urethral strictures is urethroplasty, which has a lower recurrence rate than dilatations and urethrotomies. Although recurrence rates are higher for this challenging treatment group, it is likely the only effective treatment option for chronic and severe strictures.
Urethroplasty is not regarded as a small procedure, taking three to eight hours on average in the operating room. Between 20% and 30% of urethroplasty patients may benefit from the ease of going under the knife for a shorter period of time and going home the same day. On average, hospital stays last two to three days. Seven to ten days may be needed for hospitalization for more complicated surgeries.
Fewer than ten percent of patients experience significant complications after urethroplasty, while complications, particularly recurrences, are more frequent in long and complex strictures.
Botulinum toxin is a neurotoxin produced by Clostridium botulinum species of bacteria. This powerful toxin, which is the most poisonous substance known to mankind, has been used in highly dilute concentrations in urology. This review examines the various applications of botulinum toxin sub-type A (BTA) in the field of Urology.
The surgical treatment of an injury or defect within the urethra's walls is known as urethroplasty. The three most frequent factors leading to urethral damage that needs to be repaired are trauma, iatrogenic injury, and infections. The gold standard treatment for urethral strictures is urethroplasty, which has a lower recurrence rate than dilatations and urethrotomies. Although recurrence rates are higher for this challenging treatment group, it is likely the only effective treatment option for chronic and severe strictures.
Urethroplasty is not regarded as a small procedure, taking three to eight hours on average in the operating room. Between 20% and 30% of urethroplasty patients may benefit from the ease of going under the knife for a shorter period of time and going home the same day. On average, hospital stays last two to three days. Seven to ten days may be needed for hospitalization for more complicated surgeries.
Fewer than ten percent of patients experience significant complications after urethroplasty, while complications, particularly recurrences, are more frequent in long and complex strictures.
Botulinum toxin is a neurotoxin produced by Clostridium botulinum species of bacteria. This powerful toxin, which is the most poisonous substance known to mankind, has been used in highly dilute concentrations in urology. This review examines the various applications of botulinum toxin sub-type A (BTA) in the field of Urology.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
Bladder carcinoma- surgery- urinary diversion
1. URINARY DIVERSION PROCEDURES -
CONTINENT POUCHES AND NEOBLADDER
Dept of Urology
Govt Royapettah Hospital and Kilpauk Medical College
Chennai
1
2. MODERATORS:
Professors:
Prof. Dr. G. Sivasankar, M.S., M.Ch.,
Prof. Dr. A. Senthilvel, M.S., M.Ch.,
Asst Professors:
Dr. J. Sivabalan, M.S., M.Ch.,
Dr. R. Bhargavi, M.S., M.Ch.,
Dr. S. Raju, M.S., M.Ch.,
Dr. K. Muthurathinam, M.S., M.Ch.,
Dr. D. Tamilselvan, M.S., M.Ch.,
Dr. K. Senthilkumar, M.S., M.Ch.
Dept of Urology, GRH and KMC, Chennai.
2
3. 1. Orthotopic
- Orthotopic neobladder
2. Heterotopic
a. Continent – cutaneous
b. Non continent – Ileal, jejunal, colonic conduit and cutaneous
ureterostomy
3. Diversion to GIT
- Ureterosigmoidostomy / rectal bladder
GENERAL OUTLINE - URINARY DIVERSION
3
Dept
of
Urology,
GRH
and
KMC,
Chennai.
4. Heterotopic continent diversion
A. Right colonic pouches
1.Indiana pouch 2. florida pouch
3. Penn pouch
B. Ileal pouches
1. kock 2.Mainz
4
Dept
of
Urology,
GRH
and
KMC,
Chennai.
6. URINARY DIVERSION BY POUCH
Fundamental principle
Creation of low pressure reservoir -
Detubularise, cross folding into spherical shape
Protect renal function
Allows volitional voiding
Socially acceptable continence 6
Dept
of
Urology,
GRH
and
KMC,
Chennai.
7. MAINTENANCE OF INTRINSIC CONTINENCE MECHANISM
Central to successful outcome
Meticulous dissection at apex during cystoprostatectomy
Nerve sparing – sexual function and continence
Maintain maximum functional urethral length
7
Dept
of
Urology,
GRH
and
KMC,
Chennai.
8. REFLUXING VS ANTIREFLUXING
Ureter – colon : Antirefluxing
Ureter to continent pouch / neobladder : refluxing
Technically simpler
No significant rate of renal deterioration
Less chance of anastomotic stricture
8
Dept
of
Urology,
GRH
and
KMC,
Chennai.
9. PATIENT SELECTION
Willing to follow a prescribed voiding time regimen
Ability to generate adequate valsalva pressure to empty
Ability to perform CSIC
Normal renal function
9
Dept
of
Urology,
GRH
and
KMC,
Chennai.
10. CONTRAINDICATIONS
Severe neurological illness
Psychiatric patients
IBD
Ca involving Prostatic urethra, urethral stricture
Abnormal RFT , Cr >2mg% & GFR<35ml/min
Additional solute absorption - Dyselectrolytemia
Additional water absorption
Hyperammonia – liver dysfunction
10
Dept
of
Urology,
GRH
and
KMC,
Chennai.
11. Continent catheterizing pouches
Two favourable site for stoma
1. Umbilicus – Aged , Move in wheel chair
2. Lower abdominal quadrant – at rectus muscle bulge –
ambulant
11
Dept
of
Urology,
GRH
and
KMC,
Chennai.
12. General techniques - to create dependable, catheterizable continence zone
A. For right colon pouches – Appendiceal stump
- appendiceal tunneling procedures are the simplest
- in situ or transposed appendix is tunneled into the cecal taenia
Unfavourable situation
1. Appendix may be unavailable - prior appendectomy , construction of a similar tube fashioned
from ileum (Woodhouse and MacNeily) or from the wall of the right colon (Lampel)
2. Appendiceal stump may be too short to reach the anterior abdominal wall or umbilicus
continence mechanism remains a very this attractive and reliable continence mechanism 12
Dept
of
Urology,
GRH
and
KMC,
Chennai.
14. B. Tapered and/or imbricated terminal ileum and ileocecal valve
continence mechanism
- used in right colon pouches
- imbrication or plication of the ileocecal valve region along with tapering of
the more proximal ileum in the fashion of a neourethra
- afford a reliable continence mechanism
14
Dept
of
Urology,
GRH
and
KMC,
Chennai.
16. C. Intussuscepted nipple valve or the flap valve continence
mechanism - which avoids the need for intussusception.
- creation of nipple valves - most technologically demanding
- highest complication and reoperation rate
- significant learning curve
- potential for stone formation on exposed staples / increased risk
for reservoir stone formation 16
Dept
of
Urology,
GRH
and
KMC,
Chennai.
18. Small bowel segment is isolated, and
reversely intussuscepted that effectively
apposes the mucosal surfaces of the
segment.
Tacking sutures are placed on a portion of
the circumference of the intussuscepted
segment in order to stabilize the nipple valve
Allows urine to flow freely between the
leaves of apposed ileal mucosa.
As the pouch fills, hydraulic pressure
closes the leaves, thereby ensuring
continence.
18
Dept
of
Urology,
GRH
and
KMC,
Chennai.
20. portion of intact terminal ileum freed
from mesentery for 6-8cm is
intussuscepted
10- to 15-cm portion of cecum and
ascending colon is isolated along with
two separate equal-sized limbs of
distal ileum and an additional portion
of ileum measuring 20 cm.
20
Dept
of
Urology,
GRH
and
KMC,
Chennai.
21. ILEUM INTUSSUSCEPTED, AND TWO
ROWS OF STAPLES ARE TAKEN ON THE
INTUSSUSCIPIENS ITSELF
The intussuscipiens is led through
the intact ileocecal valve, and a
third row of staples is taken to
stabilize the nipple valve to the
reservoir
21
Dept
of
Urology,
GRH
and
KMC,
Chennai.
22. A buttonhole of skin is removed from
the depth of the umbilicus and the ileal
terminus is directed through this buttonhole
A fourth row of staples is taken
inferiorly, securing the inner leaf of
the intussusception to the ileal
wall.
22
Dept
of
Urology,
GRH
and
KMC,
Chennai.
23. Most reliable.
concept of using the buttressed ileocecal valve as a dependable
continence mechanism that can withstand the trauma of
intermittent catheterization was first reported by Rowland and
colleagues (1987) from Indiana University
Ureters anastomosed with pouch and terminal ileum as
neourethra
23
Dept
of
Urology,
GRH
and
KMC,
Chennai.
24. A segment of terminal ileum approximately 10 cm in length along with the entire right colon is
isolated. B, Appendectomy is performed and the appendiceal fat pad obscuring the inferior margin of
the ileocecal junction is removed by cautery. C, The entire right colon is opened along its
antimesenteric border
24
Dept
of
Urology,
GRH
and
KMC,
Chennai.
25. D, Interrupted Lembert sutures are taken over a short distance (3 to 4 cm) in two rows for the double
imbrication of the ileocecal valve E, Application of apposing Lembert sutures on each side of the terminal
ileum. F, Excess ileum can be tapered by stapling technique
25
Dept
of
Urology,
GRH
and
KMC,
Chennai.
26. Similar to Indiana pouch except appendix used based on
Mitrofanoff principle as a continence mechanism .
The appendix is left attached to the cecum and buried in to the adjacent cecal
taenia
26
Dept
of
Urology,
GRH
and
KMC,
Chennai.
27. The entire ascending colon and the right
third or half of the transverse colon is
isolated along with 10 to 12 cm of ileum
Upper extremity of the large bowel
is mobilized laterally in the fashion
of an inverted U. The medial limbs
of the U are sutured after the bowel
is spatulated.
The bowel plate is then closed side to side. 27
Dept
of
Urology,
GRH
and
KMC,
Chennai.
28. ILEAL POUCH - KOCK
28
Dept
of
Urology,
GRH
and
KMC,
Chennai.
29. ILEAL POUCH – KOCK
A , 15-cm segment of terminal ileum is isolated and opened along its
antimesenteric wall.
The proximal 10 cm will serve as the continent intussusception, and the
distal 5 to 10 cm as the patch. The size of the patch will vary according to
the size of the excised segment.
B, An Allis or Babcock clamp is advanced into the ileal terminus; the full
thickness of the intussuscipiens is grasped, and it is prolapsed into the
pouch.
C, Three rows of 4.8-mm staples are applied to the intussuscepted nipple
valve using the TA-55 stapler.
29
Dept
of
Urology,
GRH
and
KMC,
Chennai.
31. D, A small buttonhole is made in the back wall of the ileal plate to allow the
anvil of the TA-55 stapler to be passed through and advanced into the nipple
valve. The figure shows two valve mechanisms
A 2.5-cm wide strip of absorbable mesh is placed through additional
windows of Deaver at the base of each nipple valve. The mesh strips are
fashioned into collars.
G, The collars are sewn to the base of the pouch as well as to the ileal
terminus with seromuscular sutures.
31
Dept
of
Urology,
GRH
and
KMC,
Chennai.
32. T POUCH ILEAL NEOBLADDER
Kock pouch + serous-lined ileal trough instead of intussuscepted nipple
valve
less ileum required
no nipple valve so less complications & no staples so less stones
preserves blood supply so less ischemic stenosis of valve
can overcome short ureters by harvesting longer afferent ileal limb
32
Dept
of
Urology,
GRH
and
KMC,
Chennai.
34. A, A 70-cm segment of terminal ileum is isolated 15 to 20 cm from the ileal cecal
valve.
B, A proximal 10-cm segment is isolated and rotated toward what will become the
reservoir in an isoperistaltic direction. The distal 12 to 15 cm is rotated toward the
reservoir in an antiperistaltic direction.
C, The windows of Deaver are opened to allow the walls of the W reservoir to be
apposed behind the valve mechanisms. Penrose drains are passed to guide suture
passage.
D, Horizontal mattress sutures of 3-0 silk are passed through each window. The
distal continence mechanism is longer than the proximal antireflux mechanism.
34
Dept
of
Urology,
GRH
and
KMC,
Chennai.
35. E, The proximal and distal mechanisms are tapered with a metal gastrointestinal anastomosis stapler.
F, The bowel is incised along its antimesenteric border where it will overlie the two Ts.
Distal to the Ts, the bowel is incised close to the approximated limbs of the reservoir 35
Dept
of
Urology,
GRH
and
KMC,
Chennai.
36. G, The ostia of the valves are secured to
the bowel wall with interrupted
absorbable sutures. The two flaps of
ileum are closed over the Ts with
running absorbable sutures.
H, The back wall of the reservoir is
closed with running absorbable sutures.
I, The lateral walls are folded medially
and the construction is completed with
running absorbable sutures.
36
Dept
of
Urology,
GRH
and
KMC,
Chennai.
37. POST OP
intraoperative testing for pouch integrity and continence
mechanism – to be tested
The pouch is filled with saline, the continence mechanism catheter
is removed, and the pouch is compressed lightly to look for points
of leakage
To test the continence mechanism for its ability to contain urine
to ensure ease of catheter passage. 37
Dept
of
Urology,
GRH
and
KMC,
Chennai.
38. Postoperatively, larger-bore catheter used for drainage of the pouch should be irrigated at
frequent intervals to prevent mucous obstruction
performed at 4-hour intervals by simple irrigation with 45 to 50 mL of saline
On 7th POD - contrast study to be performed to ensure pouch integrity. If no leaks are
noted, ureteral stents can be removed
suction drain is removed
The patient is taught to irrigate the tube traversing the continence mechanism at 4-hour
intervals and whenever any episode of intra-abdominal pressure or discomfort is
experienced.
Once these procedures have been mastered and the patient is tolerating a regular diet, the
patient can be discharged 38
Dept
of
Urology,
GRH
and
KMC,
Chennai.
39. COMPLICATIONS
2/3 of patients
experience at least
one complication
within the first 90
days after surgery
39
Dept
of
Urology,
GRH
and
KMC,
Chennai.
40. complications
Pyelonephritis
Prevented by effective antireflux mechanism
Antibiotic treatment instituted
Recurrent episodes evaluated with radiography
Failure of the antireflux mechanism or upper tract stone
formation 40
Dept
of
Urology,
GRH
and
KMC,
Chennai.
41. Pouchitis
Pain in the region of the pouch along with increased
pouch contractility.
Temporary failure of the continence mechanism
Sudden explosive discharge of urine through the
continence mechanism (rather than dribbling incontinence)
41
Dept
of
Urology,
GRH
and
KMC,
Chennai.
42. Urinary retention
Infrequent ; Most commonly seen with nipple valve.
Immediate catheterization and drainage by experienced personnel -
Coudé tipped catheter and Rarely, flexible cystoscope
Catheter left indwelling for 3 to 5 days to allow the edema and
trauma to the catheterization portal to resolve.
Before discharge, patient should be observed to successfully self-
catheterize on multiple occasions
42
Dept
of
Urology,
GRH
and
KMC,
Chennai.
43. Intraperitoneal Rupture of catheterizable pouches
•More common in the neurologic patient -- Sensation of pouch fullness may
be less distinct
•Associated with mild abdominal trauma
•Immediate pouch decompression and radiographic pouch studies.
•Large defects → Surgical exploration and pouch repair
•Amount of urinary extravasation is small, No evidence of peritonitis - Catheter
drainage and antibiotic administration enough
43
Dept
of
Urology,
GRH
and
KMC,
Chennai.
44. PATIENTS QUESTION
What kind of catheter do I use?
For nipple valves, a straight-ended 22- to 24-Fr tube; for ileocecal plication, a 20- to 22-Fr
coudétipped catheter; and for appendiceal sphincters, a 14- to 16-Fr coudé-tipped
catheter
How do I carry my catheter?
In a zipper-locked bag that can be placed in a women’s purse or a man’s coat pocket
How do I clean the stoma before catheterizing in a public facility?
With a topical antiseptic wipe (e.g., with benzalkonium chloride)
44
Dept
of
Urology,
GRH
and
KMC,
Chennai.
45. How do I lubricate the catheter?
water-soluble lubricant and inserting the tip of the catheter into the pack
What do I do with the stoma after catheterizing?
Cover it with a bandage
How do I clean my catheter after draining my pouch?
By rinsing with ordinary tap water through the inside channel and over the
outside surface before replacing the catheter in bag 45
Dept
of
Urology,
GRH
and
KMC,
Chennai.
47. • No disease at prostate apex / bladder neck
• Adequate bowel segment available
• Adequate urinary rhabdosphincter in situ
• Adequate renal function
• No compromise to cancer control
47
Dept
of
Urology,
GRH
and
KMC,
Chennai.
48. Age (elderly patients) – absent manual dexterity
Mental impairment
Severe and complex Urethral stricture disease
Neurogenic bladder
External sphincter dysfunction
High-dose preoperative radiation therapy 48
Dept
of
Urology,
GRH
and
KMC,
Chennai.
49. ▪ Adequate external sphincter function to maintain continence.
▪ Reservoir must be sufficiently compliant to maintain a low pressure
throughout the filling phase.
• Bowel segment detubularized and reconstructed in to a spherical shape.
▪ Ultimate storage volume - at least 400 to 500 mL at low pressure.
49
Dept
of
Urology,
GRH
and
KMC,
Chennai.
50. Type Cms Configuration Volume
Pressure
Camey II 60-70 U single fold 500 < 40
Kock 60 U double fold 700 < 40
Hautmann 60-80 W 500-700 25-30
Studer 60 U double fold 400-600 15-20 50
Dept
of
Urology,
GRH
and
KMC,
Chennai.
51. COMMON ORTHOTOPIC DIVERSIONS
Large capacity, spherical configuration with “W”of ileum
Ileal with long afferent limb
Intussuscepted afferent limb
51
Dept
of
Urology,
GRH
and
KMC,
Chennai.
52. A 70-cm portion of terminal
ileum is selected
The ileum is arranged in to an M or
W configuration with the four limbs
sutured to one another.
Buttonhole of ileum is removed
on an antimesenteric portion of the
ileum, and the urethroenteric
anastomosis is performed.
52
Dept
of
Urology,
GRH
and
KMC,
Chennai.
53. An ileal segment of approximately 55 cm length is
isolated about 25 cm from the ileocecalvalve.
53
Dept
of
Urology,
GRH
and
KMC,
Chennai.
54. THE DISTAL 44 CM OF THE ILEAL SEGMENT ARE OPENED
ALONG THE ANTIMESENTERIC BORDER. 54
Dept
of
Urology,
GRH
and
KMC,
Chennai.
55. End-to-side anastomosis of the ureters to the
unopened part of the tubular segment.
55
Dept
of
Urology,
GRH
and
KMC,
Chennai.
56. OVERSEWING OF THE TWO DISTAL ANTIMESENTERIC BORDERS OF THE
OPENED ILEUM TO CREATE NEOBLADDER
56
Dept
of
Urology,
GRH
and
KMC,
Chennai.
57. 61 cm of terminal ileum is
isolated. Two 22-cm segments
are placed in a U
configuration and opened
Posterior wall of the reservoir
formed by joining the medial
portions of the U with a
continuous running suture.
57
Dept
of
Urology,
GRH
and
KMC,
Chennai.
58. A 5- to 7-cm antireflux valve is made
by intussuscepting the afferent limb with
the use of Allis forceps clamps.
The afferent limb is fixed with
two rows of staples placed
within the leaves of the valve.
58
Dept
of
Urology,
GRH
and
KMC,
Chennai.
59. The valve is then fixed to the
back wall from outside the
reservoir with additional surgical
Reservoir is completed by
folding the ileum on itself and
closing.
Dependent end of the suture line
59
Dept
of
Urology,
GRH
and
KMC,
Chennai.
60. An isolated 10 to 15 cm of cecum in
continuity with 20 to 30 cm of
ileum is isolated.
The entire bowel segment is opened
along the antimesenteric border.
An appendectomy is performed.
60
Dept
of
Urology,
GRH
and
KMC,
Chennai.
61. Posterior plate of the reservoir
is constructed by joining the
opposing limbs together with a
An antireflux implantation of the
ureters through a submucosal tunnel is
performed and stented.
61
Dept
of
Urology,
GRH
and
KMC,
Chennai.
62. A buttonhole incision in the
dependent portion of the cecum
made to provide for urethral
The reservoir is closed side to side
with
a cystostomy tube and the stents
62
Dept
of
Urology,
GRH
and
KMC,
Chennai.
64. • Overall complications are similar to those related to ileal
conduit
• Ventral incisional hernia, Neobladder fistulas are the specific
complications
64
Dept
of
Urology,
GRH
and
KMC,
Chennai.
65. •Orthotopic neobladder relies on the rhabdosphincter for continence
•Most patients are continent and able to void to completion without the need
for intermittent catheterization.
is common → 20% to 50% continue to improve
beyond 12 months from surgery.
•Factors influencing continence rates --
• Age, Intestinal segment used,
• Application of a nerve sparing technique.
•Evaluation and management should be delayed until the neobladder achieve
maximal capacity ( about 6 months)
65
Dept
of
Urology,
GRH
and
KMC,
Chennai.
66. •Physical therapy with biofeedback focused on the pelvic
floor muscles
Male
•Transurethral Bulking agents
•Artificial Urinary Sphincter
Female
•Bulking agents
•Pubo vaginal slings 66
Dept
of
Urology,
GRH
and
KMC,
Chennai.
67. Failure to empty or urinary retention reported in 4% to
25%
Risk factors
Use of excessive intestinal length (> 60 cm of ileum),
Abdominal wall or incisional hernias postoperatively.
Urinary retention is best managed by intermittent self-
catheterization 67
Dept
of
Urology,
GRH
and
KMC,
Chennai.
68. Mostly struvite stones
Causes: Chronic Bacteriuria,
Urinary stasis, Mucous ,
Metabolic abnormalities,
Staples / sutures.
Prevention:
Treatment of symptomatic infection,
Irrigation
Treatment: Percutaneous vs Open
Extraction
68
Dept
of
Urology,
GRH
and
KMC,
Chennai.
69. Pouch Leakage : 1-8%
▪ Uninhibited pouch contractions
▪ Tx: Anticholinergics
Poorly compliant reservoir
Tx: Augmentation
Spontaneous Perforation of reservoir:
Rare but potentially fatal
Risk increased with previous radiation therapy
69
Dept
of
Urology,
GRH
and
KMC,
Chennai.
70. Every 4 Months First Year, Then
Every 6 Months up to 3 Years, Then Annually
Physical examination including pelvic/rectal examination
Blood chemistries and Complete blood count
Annual Visits Only
Voided urine Cytology
Urethral wash (if carcinoma in situ on pathology)
Vitamin B12 level
Prostate-specific antigen (if prostate cancer on pathology) 70
Dept
of
Urology,
GRH
and
KMC,
Chennai.