3. INTRODUCTION
AUA guidelines - open surgery should be reserved for cases when endourologic
procedures are not suitable or have failed
Performed more commonly in centers when percutaneous or endoscopic
equipment is not readily available
3
Dept of Urology, GRH and KMC, Chennai.
6. Anatrophic nephrolithotomy was first described by Smith and Boyce in 1968.
Their description involved creating a nephrotomy in the relatively avascular plane
of the kidney in order to prevent damage to the vasculature and avoid renal
atrophy
Hence,this procedure was given the name anatrophic
( not causing atrophy due to ischemia )
6
Dept of Urology, GRH and KMC, Chennai.
7. PREOPERATIVE PLANNING AND PREPARATION
Evaluation - 3 dimensional reconstruction of CT of the abdomen to understand the
spatial orientation of the renal anatomy and stone.
Function of the kidney - nuclear medicine renogram
Urine culture
If positive, oral culture–specific antibiotics should be started 7 days prior to
surgery
7
Dept of Urology, GRH and KMC, Chennai.
8. If urine culture is negative - broad-spectrum antibiotic 7 days before surgery
(complex stones may be colonized with bacteria)
Intraoperative antibiotics should cover known urine organisms and be broad
spectrum
8
Dept of Urology, GRH and KMC, Chennai.
9. OPERATIVE TECHNIQUE
A flank incision is used to access the kidney.
An 11th or 12th rib incision is made depending on the location of the kidney.
9
Dept of Urology, GRH and KMC, Chennai.
10. The pleura and diaphragm are mobilized cranially,and the peritoneum is
mobilized medially
Resection of the tip of the 12th rib is usually unnecessary
Resection of the 11th rib may be necessary if the kidney is located high in the
retroperitoneal cavity
10
Dept of Urology, GRH and KMC, Chennai.
11. The Gerota fascia is encountered and opened in a cranial-caudal fashion over the
posterior aspect of the kidney to allow for covering at the time of closure.
The kidney is fully mobilized;
11
Dept of Urology, GRH and KMC, Chennai.
12. Perinephric fat is dissected off the kidney taking care not to enter a subcapsular
plane.
Superior dissection must be performed gently to separate and free the adrenal
gland and inferior dissection to separate the lower pole.
Each renal pole should be free to facilitate dissection and further manipulation of
the renal hilum
12
Dept of Urology, GRH and KMC, Chennai.
13. The renal hilum is identified and the ureter,renal artery(ies),and renal vein(s) are
surrounded with vessel loops
The posterior segmental branch of the renal artery is typically dissected as it
courses around the posterior aspect of the renal sinus.
At this point, an intraoperative plain film or fluoroscopy can be performed to help
with planning the optimal location for nephrotomy.
Intraoperative ultrasound may also be used to facilitate stone location and help to
direct nephrotomy.
13
Dept of Urology, GRH and KMC, Chennai.
14. The posterior segment is then temporarily clamped with a bulldog clamp or
rubber shod, and the patient is given 10–20 ml intravenous methylene blue
This will result in blanching of the posterior segment of the kidney, the blue-
colored parenchyma allowing delineation of the avascular intersegmental
plane ( Brodel line )
14
Dept of Urology, GRH and KMC, Chennai.
15. •This plane is marked using Bovie
electrocautery on the capsule
•The clamp on the posterior segmental artery
is removed
15
Dept of Urology, GRH and KMC, Chennai.
16. The kidney is then surrounded by a plastic drape, 12.5 g of mannitol is given
intravenously,and 10 minutes later the renal hilum is clamped using bulldog clamps or a
vascular clamp
The kidney is covered in ice slush for
10 minutes to achieve a parenchymal
temperature of 15° C
Ice slush should be replaced at least every
30 minutes while clamped
16
Dept of Urology, GRH and KMC, Chennai.
17. Incise the capsule sharply along the previously marked line,
even if it is irregular
Make the incision as short as deemed necessary
Using a Penfield dissector or the back of a scalpel, bluntly
separate the parenchyma until the collecting system is
encountered
Take care not to dissect into the poles of the kidney
Sharply transect any interlobar vessels encountered;
few should be seen if in the appropriate avascular plane
17
Dept of Urology, GRH and KMC, Chennai.
18. Use the Potts scissors to open calyces to access
all ramifications of the stone
Open the collecting system sharply with a Potts
scissor or scalpel and expose the stone
18
Dept of Urology, GRH and KMC, Chennai.
19. Once the stone is exposed,gently free the stone with a blunt Randall forceps
19
Dept of Urology, GRH and KMC, Chennai.
20. Complex stone ramifications or stones located in calices with stenotic infundibulum
may require a separate nephrotomy incision directly over the moiety where the stone is
located;
this may decrease extension of the main
incision and prevent injury to a segmental
arterial branch
20
Dept of Urology, GRH and KMC, Chennai.
21. Inspect each calyx in succession and gently palpate the renal parenchyma to
ensure all stone is removed
A nephroscope (flexible cystoscope or ureteroscope) can be used to ensure all
calyces are free of stone
Intraoperative plain-film imaging or fluoroscopy can help identify any residual
stone
Antegrade ureteral stent is placed
21
Dept of Urology, GRH and KMC, Chennai.
22. CLOSURE
All transected vessels are oversewn with 4-0 absorbable polyglactin suture
The collecting system is then closed in a running fashion using 5-0 polyglactin
suture
Stenotic infundibula should be repaired to prevent future stone formation
22
Dept of Urology, GRH and KMC, Chennai.
23. Calicoplasty is performed by either suturing the mucosal edges of the infundibulum to the
adjacent renal pelvis, which shortens and widens the infundibulum,or by suturing the
mucosa of two adjacent infundibula together
23
Dept of Urology, GRH and KMC, Chennai.
24. The remainder of the collecting system is closed with a running 4-0 polyglactin suture
24
Dept of Urology, GRH and KMC, Chennai.
25. The renal capsule is closed using either a running 4-0 polyglactin suture or horizontal
mattress stitches over a fat bolster to prevent tearing of the capsule
25
Dept of Urology, GRH and KMC, Chennai.
26. The ice slush is removed,and the bulldog clamps are removed
The patient is given another dose of 12.5 g of mannitol to decrease renal reperfusion
injury
The kidney is then bathed in warm saline with rapid return of good turgor
26
Dept of Urology, GRH and KMC, Chennai.
27. Any bleeding encountered from the nephrotomy site can be controlled with light
pressure to the incision
Tissue sealants may be applied if low-volume bleeding persists
If high-volume bleeding ensues,the incision should be reopened and a search
should ensue for an actively bleeding vessel
27
Dept of Urology, GRH and KMC, Chennai.
28. The Gerota fascia is then reapproximated over the incision using 2-0 polyglactin
sutures
A Jackson Pratt drain is placed posterior to the kidney and brought out through a
separate stab incision
The fascial layers and skin are closed in a standard fashion
28
Dept of Urology, GRH and KMC, Chennai.
29. POSTOPERATIVE CARE AND COMPLICATIONS
Hemoglobin and creatinine are closely monitored for hemorrhage and renal insufficiency
Allowed to ambulate in the next morning if stable
The urethral catheter is removed on the second or third day if no significant urine leak is
evident,
The Jackson Pratt drain is removed when output is less than 50–100 mL over 24 hours
The patient is discharged with oral antibiotics for 5–7 days and the ureteral stent is removed 4
weeks postoperatively
29
Dept of Urology, GRH and KMC, Chennai.
30. Pain is common because of the size of the incision
A thoracic epidural or a lidocaine infusion pump can be considered to help reduce
postoperative pain
Pulmonary atelectasis is common and can be reduced with aggressive incentive
spirometry and ambulation
30
Dept of Urology, GRH and KMC, Chennai.
31. Pneumothorax is a possible complication with a flank incision and occur in less
than 5% of patients
Venous thrombosis can occur and can be prevented with sequential compression
devices
31
Dept of Urology, GRH and KMC, Chennai.
32. Delayed hemorrhage can occasionally occur as a result of breakdown of absorbable
sutures that were used to ligate intrarenal vessels
This should initially be treated conservatively with fluids and transfusion if necessary
If multiple transfusions are required,superselective angioembolization can be
performed to stop the bleeding
Bleeding that occurs 1–4 weeks postoperatively may indicate the formation of an
arteriovenous fistula or false aneurysm
32
Dept of Urology, GRH and KMC, Chennai.
33. Persistent infection may indicate residual stone burden
This requires antibiotic therapy and subsequent percutaneous or retrograde
surgery to remove the remaining stones
Subsequent procedures should not be undertaken for at least 6 weeks after
surgery
33
Dept of Urology, GRH and KMC, Chennai.
35. PREOPERATIVE PREPARATION,PLANNING, POSITION, AND INCISION
Similar to anatrophic nephrolithotomy,urine culture,axial imaging, and basic lab
tests should be obtained prior to surgery.
This procedure should not be performed if the patient has an intrarenal pelvis
The patient is prepped and positioned similarly to anatrophic nephrolithotomy
A flank incision is made below either the 11th or 12th rib depending on the
position of the kidney
35
Dept of Urology, GRH and KMC, Chennai.
36. OPERATIVE TECHNIQUE
Gerota fascia is incised in a cranio-caudal direction
The perinephric fat is dissected off the kidney taking
care not to enter a subscapular plane
The proximal ureter is encountered and isolated
The ureter is dissected proximally to the renal pelvis
Care is taken not to damage the posterior segmental artery as it crosses just inside the
posterior renal sinus
36
Dept of Urology, GRH and KMC, Chennai.
37. A U-shaped incision is made in the renal pelvis over the stone using a hooked 12-blade
scalpel or a Potts scissor,with the apex of the incision at least 1 cm away from the
ureteropelvic junction
37
Dept of Urology, GRH and KMC, Chennai.
38. If multiple small stones are present,pass an 8-French feeding tube down the ureter to
prevent stone migration
Once the stone is exposed,a blunt Randall forceps is used to gently grasp and remove the
stone
38
Dept of Urology, GRH and KMC, Chennai.
39. EXTENDED PYELOLITHOTOMY AND RESIDUAL CALYCEAL STONES
If any ramifications of the stone enter a calyx making it difficult to remove the stone, an
extended pyelolithotomy can be performed by reflecting the renal parenchyma and
extending the pyelotomy incision into the respective infundibulum
39
Dept of Urology, GRH and KMC, Chennai.
43. If residual stone exists in a
calyx that cannot be removed
through the infundibulum,
locate the stone by pushing it
towards the capsule with a
clamp of a finger
43
Dept of Urology, GRH and KMC, Chennai.
44. If residual stone exists in a
calyx that cannot be removed
through the infundibulum,
locate the stone by pushing it
towards the capsule with a
clamp of a finger
Sharply incise the capsule
circumferentially (Radial
nephrotomy) over the stone,
and then bluntly dissect the
parenchyma using a Penfield
dissector or the back of a
scalpel
44
Dept of Urology, GRH and KMC, Chennai.
45. If residual stone exists in a
calyx that cannot be removed
through the infundibulum,
locate the stone by pushing it
towards the capsule with a
clamp of a finger
Sharply incise the capsule
circumferentially (Radial
nephrotomy) over the stone,
and then bluntly dissect the
parenchyma using a Penfield
dissector or the back of a
scalpel
Extract the stone through
the nephrotomy with a
blunt Randall forceps
The nephrotomy is
closed using horizontal
mattress sutures over fat
bolsters
45
Dept of Urology, GRH and KMC, Chennai.
46. If the parenchyma is thick,it may be useful to place a bulldog clamp temporarily
on the renal artery
If clamping will be prolonged, cold ischemia may be employed with intravenous
mannitol administration
Close the nephrotomy with horizontal mattress 3-0 polyglactin sutures over a fat
bolster
46
Dept of Urology, GRH and KMC, Chennai.
47. COAGULUM TECHNIQUE
Obtain two bags of thawed cryoprecipitate (about 30 mL total) and keep them at room
temperature
Add a few drops of methylene blue
Obstruct the ureter using a wrapped Penrose drain
Place a small Angiocath needle into the renal
pelvis and aspirate any residual urine
47
Dept of Urology, GRH and KMC, Chennai.
48. Add 1 mL of 10% calcium chloride solution into the syringe with the cryoprecipitate
immediately prior to injection.
Through the Angiocath, inject the cryoprecipitate solution to fill, but do not overfill the
renal pelvis, then remove the Angiocath.
Wait for 5 minutes
Open the pelvis with a U-shaped incision
and carefully extract the coagulum
ensuring it is removed intact
48
Dept of Urology, GRH and KMC, Chennai.
49. Thoroughly irrigate the renal pelvis and ureter.
This technique is particularly useful when multiple stones are located in the pelvis
and collecting system, to prevent stone migration to the ureter,or multiple remote
calculi during stone manipulation.
49
Dept of Urology, GRH and KMC, Chennai.
50. CLOSURE
A nephroscope (flexible cystoscope or ureteroscope) can be used to evaluate the
calyces to ensure no residual stone remains
An antegrade double-J stent is then placed
for drainage
50
Dept of Urology, GRH and KMC, Chennai.
51. The renal pelvis is closed with running 5-0 polyglactin suture
51
Dept of Urology, GRH and KMC, Chennai.
52. Irrigate the wound copiously
The Gerota fascia is reapproximated using 2-0 polyglactin sutures
A Jackson Pratt drain is placed posterior to the kidney through a separate stab
incision
The fascial layers and skin are closed in a standard fashion
52
Dept of Urology, GRH and KMC, Chennai.
53. POSTOPERATIVE CARE AND COMPLICATIONS
Postoperative care is similar to that for patients who have undergone anatrophic
nephrolithotomy
Complications are similar to anatrophic nephrolithotomy,with significantly less risk
of bleeding or transfusion.
Acute tubular necrosis rates are lower because of a lack of interruption in renal
blood flow.
Subsequent ureteropelvic junction obstruction is a rare possible complication of
this procedure.
53
Dept of Urology, GRH and KMC, Chennai.
55. Current indications include
stones with a low likelihood of treatment success using extracorporeal shock wave
lithotripsy (ESWL),ureteroscopy,or percutaneous techniques;
secondary treatment for treatment failures after less invasive techniques;
medically underserved areas or developing countries without access to
ureteroscopic or lithotripsy equipment;
In patients who have a planned open or laparoscopic procedure for another
condition in which simultaneous treatment of the stone is requested
55
Dept of Urology, GRH and KMC, Chennai.
56. PREOPERATIVE PLANNING
It is imperative to know the location of the stone before performing
ureterolithotomy because this will impact surgical approach.
A recent computed tomography (CT) scan or kidneys–ureter– bladder (KUB)
radiography study demonstrating the stone location is required before performing
ureterolithotomy.
56
Dept of Urology, GRH and KMC, Chennai.
57. If there is concern about a nonfunctioning kidney based on preoperative imaging,
a dimercaptosuccinic acid (DMSA) scan is recommended to assess renal function.
If the stone is present in association with a poorly functioning kidney, the patient
may be better treated with a nephrectomy as opposed to a ureterolithotomy.
A urine culture should be obtained before the procedure,and the patient should
be treated with culture-specific antibiotics if a urinary tract infection is present.
57
Dept of Urology, GRH and KMC, Chennai.
58. The surgical approach for an open ureterolithotomy depends on the location of the
stone.
For all locations, an extraperitoneal approach can be performed.
However,if the patient is undergoing a concomitant intraperitoneal surgery for
another indication, a transperitoneal approach can be used.
58
Dept of Urology, GRH and KMC, Chennai.
59. Proximal ureter:
A supracostal,subcostal,or flank incision provides optimal exposure.
Alternatively,a lumbotomy can be used for proximal stones
If needed, a midline extraperitoneal or intraperitoneal approach can also be
used.
59
Dept of Urology, GRH and KMC, Chennai.
60. Distal ureter:
approached extraperitoneally via a low midline, Pfannenstiel, or Gibson incision.
60
Dept of Urology, GRH and KMC, Chennai.
61. Generally,the ureter can be accessed extraperitoneally.
Care should be taken in the dissection of the ureter to preserve as much
periureteral tissue as possible to minimize stone migration and ureteral
devascularization.
The stone can be located either by visualizing a bulge within the ureter or by
gentle palpation
61
Dept of Urology, GRH and KMC, Chennai.
62. After the stone is identified, a vessel loop
should be placed around the ureter both
proximally and distally to the stone to prevent
migration of the stone
62
Dept of Urology, GRH and KMC, Chennai.
63. The ureter is opened longitudinally over the
stone with a scalpel and extended with Potts
scissors if needed
63
Dept of Urology, GRH and KMC, Chennai.
64. The stone is then loosened from the ureteral wall and
removed intact
After removal of the stone,a 5-Fr feeding tube is
placed proximally and distally to interrogate the
ureter for remaining stone fragments
64
Dept of Urology, GRH and KMC, Chennai.
65. A stent can be placed at the discretion of the surgeon but is recommended to
control any potential urinary leaks that could result in stricture
The ureterotomy is closed longitudinally with interrupted absorbable sutures.
The ureter can be wrapped with periureteral fat, and a drain is placed.
65
Dept of Urology, GRH and KMC, Chennai.
66. The drain should be placed near the ureterotomy but not in direct contact.
A Foley catheter is left in place.
The Foley catheter can be removed on postoperative day 1, and the drain can be
removed 24 hours later if output is low.
66
Dept of Urology, GRH and KMC, Chennai.