Bill Faloon on Anti-Aging Drugs at DaVinci 50 Conference, 2021maximuspeto
In this presentation, Bill Faloon gives an update on the prospects of anti-aging drugs at the DaVinci 50 Masters Conference in Key Largo, Florida on April 29th, 2021.
Age Reversal Update from Bill Faloon on December 15th 2020maximuspeto
Bill Faloon of LifeExtension reviews several recent age-reversal topics including the remarkable effects of hyperbaric oxygen on telomere length and senescence in humans and clinical studies designed to assess age-reversal potential of multiple interventions.
Bill Faloon on Anti-Aging Drugs at DaVinci 50 Conference, 2021maximuspeto
In this presentation, Bill Faloon gives an update on the prospects of anti-aging drugs at the DaVinci 50 Masters Conference in Key Largo, Florida on April 29th, 2021.
Age Reversal Update from Bill Faloon on December 15th 2020maximuspeto
Bill Faloon of LifeExtension reviews several recent age-reversal topics including the remarkable effects of hyperbaric oxygen on telomere length and senescence in humans and clinical studies designed to assess age-reversal potential of multiple interventions.
Pluripotent Stem Cells and their applications in disease modelling, drug disc...tara singh rawat
This ppt gives an insight of the potential and possibilities of pluripotent stem cells research in disease modelling, drug discovery and regenerative medicine
Induced Pluripotent Stem Cells and Somatic Cardiac Regeneration— An Explorato...Robert Chen
In the exploratory analysis, the functional pathway networks of nucleostemin and iPS interact via TP53 (tumor protein P53) and Fgf (fibroblast growth factor), which could be further investigated to provide clues for the future research of postnatal cardiac regeneration.
Pluripotent Stem Cells and their applications in disease modelling, drug disc...tara singh rawat
This ppt gives an insight of the potential and possibilities of pluripotent stem cells research in disease modelling, drug discovery and regenerative medicine
Induced Pluripotent Stem Cells and Somatic Cardiac Regeneration— An Explorato...Robert Chen
In the exploratory analysis, the functional pathway networks of nucleostemin and iPS interact via TP53 (tumor protein P53) and Fgf (fibroblast growth factor), which could be further investigated to provide clues for the future research of postnatal cardiac regeneration.
A feature run by the monthly magazine for the polo community highlighting the latest in cutting edge regenerative therapy and how it has been translated for equine veterinary use from the human medical world.
IOSR Journal of Pharmacy and Biological Sciences(IOSR-JPBS) is an open access international journal that provides rapid publication (within a month) of articles in all areas of Pharmacy and Biological Science. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Pharmacy and Biological Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, whereas not all genotoxic substances are mutagenic
Achieving High Yields in Scalable Xeno Free Culture Formats with Mesenchymal ...Merck Life Sciences
Watch the presentation of this webinar here: https://bit.ly/3ryE5ST
Optimize your mesenchymal stem cell growth. Join our webinar to learn more about our GMP-compliant xeno free media formulation that supports high performance expansions and compatibility with scalable xeno free manufacturing conditions.
Optimizing ex vivo cell expansion processes in preparation for clinical use is a critical step in cell therapy manufacturing. Given the curative and lifesaving impacts these therapies can have on patients, overcoming roadblocks with scalability and supply chain, using high quality raw materials are essential for therapeutic access.
The GMP-compliant Stemline® XF MSC Medium and cocktail promotes expansion of human mesenchymal stromal/stem cells (hMSCs) to high densities while maintaining cell identity and quality. This product was designed for derivation and expansion of MSCs using xeno free conditions in planar and microcarrier-based culture platforms, easing the transfer between research, clinical, and manufacturing scale cultures.
In this webinar, you will:
• Explore the current landscape and future trends of cell culture media for adult mesenchymal stem cells
• Discover ways to derive MSC's from Bone Marrow in Xeno Free conditions from static to microcarrier-based suspension culture platforms.
• Learn how Stemline® XF MSC Media provides robust performance and reduces scalability roadblocks
Presented by: Kathleen Ongena, Ph.D., Head of Customer Applications and Mark Ventresco, Cell Therapy Product Manager
Achieving High Yields in Scalable Xeno Free Culture Formats with Mesenchymal ...MilliporeSigma
Watch the presentation of this webinar here: https://bit.ly/3ryE5ST
Optimize your mesenchymal stem cell growth. Join our webinar to learn more about our GMP-compliant xeno free media formulation that supports high performance expansions and compatibility with scalable xeno free manufacturing conditions.
Optimizing ex vivo cell expansion processes in preparation for clinical use is a critical step in cell therapy manufacturing. Given the curative and lifesaving impacts these therapies can have on patients, overcoming roadblocks with scalability and supply chain, using high quality raw materials are essential for therapeutic access.
The GMP-compliant Stemline® XF MSC Medium and cocktail promotes expansion of human mesenchymal stromal/stem cells (hMSCs) to high densities while maintaining cell identity and quality. This product was designed for derivation and expansion of MSCs using xeno free conditions in planar and microcarrier-based culture platforms, easing the transfer between research, clinical, and manufacturing scale cultures.
In this webinar, you will:
• Explore the current landscape and future trends of cell culture media for adult mesenchymal stem cells
• Discover ways to derive MSC's from Bone Marrow in Xeno Free conditions from static to microcarrier-based suspension culture platforms.
• Learn how Stemline® XF MSC Media provides robust performance and reduces scalability roadblocks
Presented by: Kathleen Ongena, Ph.D., Head of Customer Applications and Mark Ventresco, Cell Therapy Product Manager
Normal tissues and tumors arise from a population of cells termed stem cells. In vivo experiments have provided evidence of the presence of stem cells throughout the mouse mammary gland. Premalignant mammary outgrowths that faithfully recapitulate the mammary epithelial cell lineage upon transplantation contain cells with tumor-forming potential. Cell sorting techniques have identified putative mouse mammary stem cell surface markers and human breast cancer stem cell surface markers. These markers do not identify only stem cells but in fact distinguish a mixed population of cells containing stem cell activity. Previous studies have demonstrated that clones arising from single cells in vitro can be categorized into three types based on the clone morphology. Here, we report the characterization, both in vitro and in vivo, of clonogenic cells from a non-tumorigenic mammary epithelial population and those from an erbB2-induced mammary tumor. We found that clones arising from normal mammary cells expressed different patterns of stem and developmental marker between the clone types and compared to the expression patterns observed on clones that developed from tumorigenic mammary cells.
The results of the study show a promising role of Acacia Honey, a natural product with proven therapeutic effects on skin wound healing. It accelerated the initial stage of corneal wound healing without the side effects found when using conventional treatments which contain preservatives. Corneal keratocytes cultured in media supplemented with 0.025% Acacia Honey showed an increase in proliferative capacity while retaining their morphology, gene and protein expressions with normal cell cycle.
Bill Faloon at Healinc Summit, 2024 in The Bahamasmaximuspeto
In this presentation, Bill Faloon highlights the rapid, recent progress on age-reversal research in mice and primates as humanity gets closer to implementing age-reversal technologies into human medicine. These are his slides from his presentation at the Healinc Summit at the Atlantis Hotel in the Bahamas on April 29th, 2024.
Bill Faloon on Age Reversal at Old Fort Bay Club Bahamas 2024maximuspeto
In this presentation, Bill Faloon highlights the rapid, recent progress on age-reversal research in mice and primates as humanity gets closer to implementing age-reversal technologies into human medicine. These are his slides from his presentation at the Old Fort Bay Club in the Bahamas in 2024.
Bill Faloon's 2023 RAADfest Presentation Slidesmaximuspeto
Bill Faloon presented at RAADfest 2023. Topics he emphasized included the delay in translating research findings into routine medical practice, delays and restrictions by the FDA, and advancements in age-reversal since RAADfest 2022.
Bill Faloon on What is Delaying Regenerative Medicine in 2023maximuspeto
On April 20th, 2023, Bill Faloon presented at the HEALinc Summit in the Bahamas and described some challenges currently delaying the development of regenerative medicine, including zealous regulatory overreach.
Bill Faloon on Interventions Designed to Reverse Human Agingmaximuspeto
In his presentation at the HEALinc Summit in April 2023, Bill Faloon describes some interventions designed to reverse human aging. These interventions include senolytics, rapamycin, and NAD+ replenishment among others.
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentationmaximuspeto
On April 20th, 2023, Bill Faloon presented an extensive presentation at the HEALinc Summit about human age-reversal technologies. There, he introduced the new Perpetual Project—an informal association focused on assessing and altering biomarkers with experimental age-reversal technologies to extend the lives of its members.
Bill Faloon on what's delaying regenerative medicine in 2023.pptxmaximuspeto
Bill Faloon describes how excessively restrictive drug testing and approval policies have delayed medical developments that could greatly extend healthy human life. These are presentation slides for a presentation he gave on February 9th, 2023 in West Palm Beach Florida with Jonathan Emord, who is considering running for a Senate seat in the state of Virginia with a focus on reform of drug testing and approval procedures in the United States.
Fruit Fly Combo Treatment Life Extension.pptxmaximuspeto
These three presentation slides by Bill Faloon illustrate the additive effects of multiple life-extension interventions when administered in fruit flies (lithium, rapamycin, and trametinib). This finding suggests that it could be very beneficial to experiment with multi-intervention clinical studies in aging humans.
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversalmaximuspeto
This is the presentation slides for Bill Faloon's keynote presentation about the prospects for human age reversal, which he presented at RAADfest 2022 on Thursday October 6th.
Clinical trials for human age-reversal therapies are urgently needed because thousands of people are dying from age-related diseases every day. We can petition Congress and the FDA to amend clinical trial constraints to allow for individuals to join clinical trials with adequate informed consent.
Bill Faloon gives update about human age-reversal clinical studiesmaximuspeto
In this presentation, Bill Faloon gives an update on clinical studies aimed and reversing age-related degeneration in humans at the DaVinci 50 Masters Conference in Key Largo, Florida on April 29th, 2021.
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021maximuspeto
In this presentation, Bill Faloon gives an update on the prospects for human age reversal medicine at the DaVinci 50 Masters Conference in Key Largo, Florida on April 29th, 2021.
Bill Faloon at DaVinci 50 about stroke risk and blood pressuremaximuspeto
In this presentation on Thursday April 29th, 2021 at the DaVinci 50 Mastermind Conference in Key Largo, Florida, Bill Faloon discusses how to optimize blood pressure to reduce stroke risk.
Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021maximuspeto
Bill Faloon presented an age reversal update on a webinar hosted by the Coalition for Radical Life Extension on January 23rd, 2021. These are his presentation slides.
Bill Faloon at Healthy Masters Conference 2020maximuspeto
Bill Faloon explores the recent hyperbaric oxygen study published in the journal Aging, in which the researchers reported a 20% increase in average telomere length in the human study volunteers.
2019.12.08 Bill Faloon at Confidential Cures Summit Dec 8 2019.maximuspeto
Bill Faloon presents some remarkable advancements in human age-reversal medicine at the Confidential Cures Summit in Palm Beach Florida on December 8th, 2019.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
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Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021
1. (go to www.calendly.com/qcm for Q+A)
Amniotic Fluid-Derived
with Extra Cellular
Vesicles "ECV’s"
Amnio Matrix is an acellular amniotic derived minimally manipulated
tissue available for research purposes only
Amniotic Fluid-Derived
with Extracellular
Vesicles "EV’s"
AMNIO MATRIX
2. Chart from Dr. Arnold Caplan who is considered the “father of MSCs
Tremendous Loss of
Regenerative
capacity as we age
- By teenage years
there is 90% decrease
in regenerative
capacity
- 50 yr old bone marrow
cells provide only 2.5%
MSC’s for regeneration
This is why we are
committed to using
the highest quality
perinatal products.
Loss of Regenerative capacity
3. Parabiosis –taking youth from the young to fix the old
Rejuvenating factors provide
tissue repair and anti-aging.
The most potent of these
factors are extracellular
vesicles. Indeed, these EVs
are the mechanism by which
the “paracrine effect” works
when MSCs and other
regenerative cytotherapy is
given to patients. It’s not the
cells of the young individual,
it’s mostly the EVs that
provide the messaging payload
to create the cell rejuvenation.
Exosomes are the main EV’s.
(go to www.calendly.com/qcm for Q+A)
Young blood added to old blood is called heterochronic parabiosis
Harvard Medical School, UCLA and UC San Francisco and other institutions have created papers demonstrating the
striking benefits of young blood on cognitive function, synaptic plasticity, neurogenesis, and the cerebral vasculature of
old mice. The beneficial effects are not limited to the brain, and the operative factors can be identified, as one study
reports that growth differentiation factor GDF11 empowers young blood to bestow regenerative oomph to old muscle.
2014 Zilkha Symposium on Alzheimer’s Disease and Related Disorders | ALZFORUM
4. The heart of the third
trimester mother is akin to
that of an elite athlete,
except that the race is for
three months instead of
minutes. If a male or non-
pregnant woman tried to
maintain this level of
cardiac output they would
die.
Nanosomes shared by the
fetus, placenta and
mother, protect the mother
from the stresses and
rigors of pregnancy.
Pregnancy: A natural example of heterochronic parabiosis.
Amnio Matrix: Amniotic fluid EVs (Extra Cellular Vesicles)
are the ultimate toolbox for tissue growth and repair and
immune modulation.
All of the physiological changes the mother experiences, tissue
growth, immune modulation, etc must come from communication with
the fetus via Nanosomes found in Amniotic Fluid.
All the material supplies needed for fetal growth must be delivered
within an exquisitely refined inventory of EV’s via Growth Factors,
Chemokines, Hyaluronic Acid combined with Nanosomes in Amnio
Matrix.
Unique and specific cargo ratios only seen in natural amniotic fluid
filtered and concentrated and sterilized into Amnio Matrix.
Heterochronic parabiosis –pregnancy
Amnio Matrix is an acellular amniotic derived minimally
manipulated tissue available for research purposes only
5. Amniotic Fluid and Tissue Provides Everything Needed
Amniotic Fluid contains Hyaluronic Acid,
over 300 growth factor, Chemokines,
Cytokines and an abundance of
Mesenchymal Stem Cells “MSC’s” which
release Extracellular Vesicles “EV’s” to
signal and direct the production of all the
cells needed to create a complete
healthy body. Amnio Matrix captures
this regenerative capacity.
Amnio Matrix is an acellular amniotic
derived, minimally manipulated tissue
available for research purposes only
(go to www.calendly.com/qcm for Q+A)
6. Amnio MatrixTM
Breakthrough in Regenerative Therapeutics
Amnio Matrix is derived from the amniotic fluid and tissue of healthy, full-term, c-section births carefully screened socially and
physically tested. A detailed questionnaire of over 60 pages is used to screen donors in addition to testing. The miraculous
synergy of hyaluronic acid, 300+ growth factors, chemokines and cytokines are included with the naturally occurring Nanosomes
which are the core regenerative extracellular vesicles "EV's" messengers. They are measured to be between 50–150 nm in size.
As such they can pass though the placental barrier and the blood-brain barrier. Unlike exosomes derived from culture-expanded
placental MSCs, Amnio Matrix is acellular allograft produced by filtering the heterogeneous population of regenerative cells
including epithelial cells, endothelial and hematopoietic progenitors and mature leucocytes (white blood cells), etc. However, the
main Nanosome content of the Amnio Matrix come from what the Mesenchymal Stem Cells “MSC” have released.
They accumulate in the amniotic fluid during pregnancy (a phase of pro-growth and anti-inflammation) creating a regenerative
fluid and tissue which is advantageous over sole EVs created by culture-expanded cells. Our clinic has a foundation of 20 years
of experience in regenerative therapy with an unchanging passion to improve patient outcomes. This gave birth to the research
and development years working with patients to develop Amnio Matrix. Amnio Matrix represents a breakthrough in regenerative
Nanosome therapeutics.
Far more powerful than any other EV product in the market.
Far more flexibility in treatment than any other EV product in the market.
(go to www.calendly.com/qcm for Q+A)
Amnio Matrix is an acellular amniotic derived minimally
manipulated tissue available for research purposes only
7. Amnio MatrixTM
Breakthrough in Regenerative Therapeutics
1. Far more powerful than any other exosome product in the market. Amnio Matrix has more Nanosomes per cc measured by
third party testing. Through a proprietary method of carefully stressing the mesenchymal stem cells in the Amniotic fluid
Matrix achieves this high yield. When compared to other exosome products it has 5 to 10 times more Nanosomes per cc.
A vial of Amnio Matrix is 1.5 cc. It contains on several trillion Nanosomes in each vile. The laboratory is in full compliance with
cGMP and cGTPs. Each batch is sent for 3rd party testing per specific release criteria in accordance with FDA guidelines. In the
most recent 3rd party testing Amnio Matrix batches showed over 6 trillion Nanosomes in the 1.5cc vial. This concentration of 4
trillion Nanosomes per cc represents 5 times more than what reported by the closest competitive product and over 10 times more
than most of the market.
2. Multiple injections from one vial. Matrix is developed with a proprietary manufacturing method as compared to other
exosome products. This allows for reconstitution with saline or PRP allowing for multiple injections. This allows the clinic to perform
multiple treatments (2 to 4) per vial which brings the cost way below other products in the market.
(go to www.calendly.com/qcm for Q+A)
Matrix is an acellular amniotic derived minimally
manipulated tissue available for research purposes only
8. Filtered Sterilized
All manufacturing is
performed by qualified,
trained scientists under
cGMP laboratory with
a ISO7 clean room.
Release criteria
including sterility is
tested by independent
third party labs.
The raw amniotic fluid is collected by FDA-
approved and AABB accredited cord-blood
banks within the USA and shipped
overnight to our labs. Mothers are
consented and tested for infectious
diseases and other exclusion criteria at the
time of normal full term pregnancy in
situation of planned delivery by C-section.
Centrifuged
Using proprietary techniques, requiring
minimal manipulation of the material, raw
amniotic fluid is transformed into Amnio
MatrixTM. The vials are quarantined for 14
days while lots are tested by independent
labs for sterility and endotoxin. We have a
100% clean record over the 3 years that
our scientists have been producing Amnio
MatrixTM.
Vials are shipped on dry ice within tamper-
proof insulated shippers, together with
product details and a certificate of analysis.
Prior to delivery the vials should be stored
in a -80c degrees freezer. The cryovials are
never submerged in the liquid phase of
liquid nitrogen.
Manufactured at the highest quality standards
(go to www.calendly.com/qcm for Q+A)
Amnio Matrix is an acellular amniotic derived minimally
manipulated tissue available for research purposes only
9. The difference between MatrixTM
and
alternative amniotic products.
Not all extracellular vesicles are exosomes
Nanosomes are between 50-150 nm and require a
specific profile. Larger EVs are non-regenerative
microvesicles and “apoptotic bodies” produced by
dying cells. We use a propriety method for filtering
micronized material. Then we apply our proprietary
sterilization process which no other laboratory has.
The retained EVs need to have a balanced profile of
surface proteins CD9, CD63 and CD81.
In the recent 3rd Party testing Amnio Matrix
showed over several trillion exosomes per 1.5ml.
(go to www.calendly.com/qcm for Q+A)
Amnio-Matrix is an acellular amniotic derived minimally manipulated tissue available for research purposes only
ZetaView Analysis
SAMPLE PARTICLE DIAMETER (nm) CONCENTRATION
Mean Mode (particles/mL)
AMNIO MATRIX Vial 1 134.2 92.5 6.30E+12
AMNIO MATRIX Vial 2 133.9 92.5 6.10E+12
AMNIO MATRIX Vial 3 137.1 87.5 7.00+12
0
20
40
60
80
100
120
140
160
CD9 CD63 CD81
10. RAADfest Patient Clinical Assessment of Amnio-Matrix
(naturally occurring hyaluronic acid, 300+ growth factors and exosomes)
(go to www.calendly.com/qcm for Q+A)
QCM Clinics, Age Reversal Network, Brazelia Integrative Wellness.
Test of the effects of an amniotic fluid–based regenerative medicine product on
markers of aging, inflammation, and kidney function. The product comes from a
fully FDA compliant cGMP laboratory with an ISO 7 certified clean room.
•Participants: 5 healthy patients, ages 65 to 85. (Those not meeting these criteria can participate in other ways.)
•Each participant to receive 2 treatments in total of 1.5 ml Amnio-Matrix.
•Treatments on Day 0 and Day 30.
•Assessments done on Day 0 and Day 45.
•Assessments: Clinical measures (done at Brazelia Integrative Wellness Center)
• Short health assessment questionnaire
• MMSE (Mini Mental State Exam)
• Blood pressure
• 30 second sit-to-stand test
•Assessments: Blood tests (done via Life Extension®/Lab Corp)
• Life Extension Male/Female Panel
• IL-6
• TNF-alpha
• Cystatin-C
Summary of clinical assessment
11. Five-Patient Clinical Assessment of Amnio-Matrix
•Treatments starts as soon as convenient for patient (ideally soon).
•Begin by contacting David Konn at QCM. Go to www.calendly.com/qcm to schedule a Zoom appointment
dck@qcmedicine.com, 561-602-0484.
•Step 1. Have blood draw for blood tests at Life Extension® Nutrition Center in Fort Lauderdale, Florida.
•Step 2. Visit 1 to Brazelia Integrative Wellness, Boca Raton, Florida. (Commence treatment within five days of blood draw.)
• Initial clinical tests.
• First treatment.
•Step 3. Visit 2 to Brazelia Integrative Wellness on day 30.
• Second treatment.
•Step 4. Visit 3 to Brazelia Integrative Wellness on day 45.
• Final clinical tests.
•Step 5. Return to Life Extension® Nutrition Center on or close to day 45 for second and final blood draw.
•Other details to be provided by David Konn and Dr. Brazelia Lazzari.
QCM and Brazelia Med Spa are interested in continuing to gather information about the efficacy of amniotic fluid–
based regenerative medicine products. Anyone interested in this treatment, whether or not they qualify for the current
clinical assessment, can contact David Konn about a longer-term, ongoing assessment that can be made available at a
significant discount for research purposes.
Go to www.calendly.com/qcm to schedule a Zoom appointment
Requirements for patients
Option on Next Page for those who don’t qualify or are not selected
12. Age Reversal Network 90-Day or 360-Day Assessment Program
(participants are limited please go to www.calendly.com/qcm for Q+A)
**OPTION 1: 3 Month Regeneration and Renewal Registry program with two
treatments and Bio Impedance testing with a research discount of 20%
**OPTION 2: 12 month Annual Complete Regeneration and Renewal Registry
with four treatments and Bio Impedance testing with a research discount of 37%
QCM Clinics, Age Reversal Network, Brazelia Integrative Wellness Center.
Test of the effects of an amniotic fluid–based regenerative medicine product via before and after
questionnaire on aging, inflammation, and overall wellness with advanced electro dermal screening.
The product Amnio Matrix comes from a cGMP ISO 7 certified clean room laboratory.
Two options for this Age Reversal Network Patient Registry
Send email to DCK@QCMedicine.com