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Applications of Magnetosomes
Presented by:
Name: MD. Toukir Ahamed Tanvir
Department of Pharmaceutical Sciences,
North South University.
Dhaka, Bangladesh.
Applications of Magnetosomes
Magnetic resonance imaging (MRI).
Magnetic hyperthermia.
Drug delivery.
Other medical applications of bacterial magnetosomes.
Magnetic resonance imaging (MRI)
• Several studies report the use of bacterial magnetosomes as
positive or negative contrast agent.
• Using MRI magnetic bacteria have natural tendency to target
tumors when they administerd intravenously.
• Positive contrast improving the visualization of the magnetic
bacteria in tumors.
Magnetic hyperthermia
• Magnetosomes are also good candidates to treat cancers
using magnetic hyperthermia.
• Magnetic hyperthermia is a technique in which magnetic
nanoparticles are administered to tumors and then heated
under the application of an alternating magnetic field.
The heat induces anti-cancer activity.
Drug delivery
• Due to the presence of various chemical groups at the surface of
magnetosomes,
• It can reduce the toxicity of anticancer drugs. E.g. doxorubicin is
highly toxic, mortality 80%. But the conjugate of magnetosomes
and doxorubicine is less toxic, mortality 20%.
• The conjugate of doxorubicin and magnetosomes have been
tasted as anti-tumor activity against hepatic cancer.
Other medical applications of
magnetosomes
• It can used to detect nucleotide polymorphism, which is
used to diagnose disease such as cancer, HTN, diabetes
etcetera.
• The magnetosomes have also been used in immune assay
to detect small nuclease, hormones or toxic detergent.

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Applications of magnetic bacteria.

  • 1. Applications of Magnetosomes Presented by: Name: MD. Toukir Ahamed Tanvir Department of Pharmaceutical Sciences, North South University. Dhaka, Bangladesh.
  • 2. Applications of Magnetosomes Magnetic resonance imaging (MRI). Magnetic hyperthermia. Drug delivery. Other medical applications of bacterial magnetosomes.
  • 3. Magnetic resonance imaging (MRI) • Several studies report the use of bacterial magnetosomes as positive or negative contrast agent. • Using MRI magnetic bacteria have natural tendency to target tumors when they administerd intravenously. • Positive contrast improving the visualization of the magnetic bacteria in tumors.
  • 4. Magnetic hyperthermia • Magnetosomes are also good candidates to treat cancers using magnetic hyperthermia. • Magnetic hyperthermia is a technique in which magnetic nanoparticles are administered to tumors and then heated under the application of an alternating magnetic field. The heat induces anti-cancer activity.
  • 5.
  • 6. Drug delivery • Due to the presence of various chemical groups at the surface of magnetosomes, • It can reduce the toxicity of anticancer drugs. E.g. doxorubicin is highly toxic, mortality 80%. But the conjugate of magnetosomes and doxorubicine is less toxic, mortality 20%. • The conjugate of doxorubicin and magnetosomes have been tasted as anti-tumor activity against hepatic cancer.
  • 7. Other medical applications of magnetosomes • It can used to detect nucleotide polymorphism, which is used to diagnose disease such as cancer, HTN, diabetes etcetera. • The magnetosomes have also been used in immune assay to detect small nuclease, hormones or toxic detergent.