This presentation provides an overview of proton therapy, including its definition, history, mechanism, and applications. Proton therapy uses a beam of protons to treat cancerous tumors. It was first suggested in 1941 and the first treatment occurred in 1954. Proton therapy offers advantages over other treatments by depositing most of the radiation dose within the tumor and minimizing exposure of surrounding healthy tissue. Common applications include brain tumors and tumors located near critical organs. While proton therapy is effective, the equipment required is very expensive to build and operate.

1. Welcome to our
presentation
Huynh Trong An
Ngo Trung
Nguyen Hoang Phi Yen
Tran Huu Loc

2. Outline
1. Definition
2. History
3. Mechanism
4. Applications
5. Others
2

3. 1. Definition
3
Proton therapy is a
type of particle
therapy which uses a
beam
of protons to irradiate
diseased tissue, most
often in the treatment
of cancer

4. 2. History
4
1941, Robert R. Wilson
suggested that energetic
protons could be an
effective treatment
method.
1954-1957, the first treatment was
performed at Berkeley Radiation
Laboratory
1961, Harvard Cyclotron
Lab and Massachusetts
General Hospital pursue
proton therapy
By 2010, these facilities were joined by
an additional seven regional hospital-
based proton therapy centers in the
United States alone, and many more
worldwide.

5. 5
3. Mechanism
The New York Times and University of Florida Proton Therapy Institute

6. 6

7. Cyclotron and synchrotron accelerators
7
Both the cyclotron and synchrotron are type of
particle accelerators
And both are used as a particle source
for high-energy collisions
Cyclotron Synchrotron

8. 8
But they each use different designs to accelerate particles.
However, they bot reply on two principles,
electricity and magnetism.

9. 9
Cyclotron

10. 10
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+

11. 11
Synchrotron

12. 12

13. 13
Cyclotron Synchrotron
Constant magnetic field
and a constant frequency
electric field
Varying electric and
magnetic fields
A cylindrical or spherical
chamber.
A torus shaped tube
Its curve becomes larger A constant radius circle
250MeV 6.84TeV

14. 14
How can the proton therapy damage tumor?
O O
PROTON BEAM
O: :O+

15. 15

16. 4. Applications
16
The chief advantage of proton therapy
• Same tumor killing properties as X-rays
• Decreased dose to normal tissues, side effects and complications
• Treating tumors close to critical organs
• Increasing the safe dose delivered to tumors, cure rates
• Ability to re-treat tumors after recurrences

17. General example.
 Brain tumors and inoperable brain lesions
17
 Tumors near the optic apparatus
 Pediatric tumors (to reduce the
risk of secondary malignancies,
and to avoid the irradiation of
growth plates)

18. Comparison with other treatment options
18

19. 5. Others
19
Cost
- For treatment
 around £90,000 per person
 $34,000 for eight weeks (medicare)
- For proton therapy machine:
$144 million to build
a cyclotron--220 tons
100-ton motorized gantry spins

20. Treatment centers
20

21. 5.3. Sum up
21

22. 22