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Ideal Anthelmintic Agent
Broad Spectrum of Action
High cure rate with single dose
Free from toxicity to host
Cost effective
But no synthetic agent meets all requirements
Why need a new
anthelmintic
Resistance of parasites to the common drugs
High costs
Side effects
Availability
Anthelmintic
plants & herbs
Synthetic medicines are very
effective in curing diseases but
also have many side effects.

Although less efficient, but
herbal plants are relatively free
from side effects.
Myrrh
Myrrh is an aromatic resin
obtained from various plant
species
of
genus
Commiphora
It’s a safe and effective
treatment for fascioliasis
and schistosomiasis at 1012 mg/kg/day for 6 days
Ocimum Sanctum Linn.
It’s also known as Sacred Basil. The essential oil contains eugenol,
β-caryophyllene, and other monoterpenes. The plant showed potent
in vitro anthelmintic activity.
Melia azedarach L.
Native to India, China and Persia.
The extract were tested against
tapeworm
and
earthworm.
Efficacy were found to be even
better than piperazine phosphate
against tapeworm.
Artemisia annua
Also known as sweet wormwood,
sweet annie, sweet sagewort.
Artemether, a methyl ether
derivative, has proven efficacy
against
S,haematobium,
S.
japonicum and S.mansoni.
Carica papaya
Linn.
Papaya
contains
benzyl
isothiocyanate
as
major
anthelmintic agent. The extracts
were tested on nematodes
(Ascaris lumricoides & Ascaridia
galli). The compound affect
energy metabolism and motor
activity of parasites.
Nigella sativa L.
Along with anthelmintic activity it’s digestive, carminative, diuretic
and astringent activities. Contains thymoquinone, & α-Pinene as
active ingredients. Shows anthelmintic activity against tapeworm
and hookworm.
Moghania vestita
It’s a leguminous root crop
White root tubers are usually eaten raw
Has a reputation as an anthelmintic
Genistien, the active ingredient, successfully
tested against various trematodes and
nematodes & has shown good results.
Juglan nigra & Tansy
Juglans nigra (black walnut) and tansy used particularly in treating
nematodes infestation, especially enterobiasis.
Enterobius vermicularis (pinworm) is most common cosmopolitan
parasite.
Mimusops elengi
An evergreen tree found in South
Asia, Southeast Asia & northern
Australia. Commonly known as
Spanish cherry, medlar, and
bullet wood.
Plant used as Astringent,
Cardiotonic,alexipharmic,
stomachic, and anthelmintic
Tannins of the plant cause
uncoupling of oxidative
phosphorylation.
Punica granatum
Linn.
Root and stem bark of the plant
used
as
astringent
&
anthelmintic. Alcoholic extract of
the plant inhibit transformation of
eggs to filariform larvae of
Haemonchus contortus. It also
shows
efficacy
against
nematodiasis.
Thymus vulgaris
Thymus vulgaris is a species of flowering plant in the mint family.
Shows a great efficacy in treating hookworm infestation at a dose of
2-3ml extract three times a day.
Hookworm infect more than 1 billion people worldwide.
Some other anthelmintic
plants and herbs
Ferula asafoetida
Embelia ribes
Picrasma excelsa

Chenopodium ambrosioides
Echinacea purpurea
Ginkgo biloba
Asparagus L.
Trifolium repens
Ficus insipida
Cucurbita maxima

Trachyspermum ammi

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Anthelmintic plants and herbs

  • 1.
  • 2. Ideal Anthelmintic Agent Broad Spectrum of Action High cure rate with single dose Free from toxicity to host Cost effective But no synthetic agent meets all requirements
  • 3. Why need a new anthelmintic Resistance of parasites to the common drugs High costs Side effects Availability
  • 4. Anthelmintic plants & herbs Synthetic medicines are very effective in curing diseases but also have many side effects. Although less efficient, but herbal plants are relatively free from side effects.
  • 5. Myrrh Myrrh is an aromatic resin obtained from various plant species of genus Commiphora It’s a safe and effective treatment for fascioliasis and schistosomiasis at 1012 mg/kg/day for 6 days
  • 6. Ocimum Sanctum Linn. It’s also known as Sacred Basil. The essential oil contains eugenol, β-caryophyllene, and other monoterpenes. The plant showed potent in vitro anthelmintic activity.
  • 7. Melia azedarach L. Native to India, China and Persia. The extract were tested against tapeworm and earthworm. Efficacy were found to be even better than piperazine phosphate against tapeworm.
  • 8. Artemisia annua Also known as sweet wormwood, sweet annie, sweet sagewort. Artemether, a methyl ether derivative, has proven efficacy against S,haematobium, S. japonicum and S.mansoni.
  • 9. Carica papaya Linn. Papaya contains benzyl isothiocyanate as major anthelmintic agent. The extracts were tested on nematodes (Ascaris lumricoides & Ascaridia galli). The compound affect energy metabolism and motor activity of parasites.
  • 10. Nigella sativa L. Along with anthelmintic activity it’s digestive, carminative, diuretic and astringent activities. Contains thymoquinone, & α-Pinene as active ingredients. Shows anthelmintic activity against tapeworm and hookworm.
  • 11. Moghania vestita It’s a leguminous root crop White root tubers are usually eaten raw Has a reputation as an anthelmintic Genistien, the active ingredient, successfully tested against various trematodes and nematodes & has shown good results.
  • 12. Juglan nigra & Tansy Juglans nigra (black walnut) and tansy used particularly in treating nematodes infestation, especially enterobiasis. Enterobius vermicularis (pinworm) is most common cosmopolitan parasite.
  • 13. Mimusops elengi An evergreen tree found in South Asia, Southeast Asia & northern Australia. Commonly known as Spanish cherry, medlar, and bullet wood. Plant used as Astringent, Cardiotonic,alexipharmic, stomachic, and anthelmintic Tannins of the plant cause uncoupling of oxidative phosphorylation.
  • 14. Punica granatum Linn. Root and stem bark of the plant used as astringent & anthelmintic. Alcoholic extract of the plant inhibit transformation of eggs to filariform larvae of Haemonchus contortus. It also shows efficacy against nematodiasis.
  • 15. Thymus vulgaris Thymus vulgaris is a species of flowering plant in the mint family. Shows a great efficacy in treating hookworm infestation at a dose of 2-3ml extract three times a day. Hookworm infect more than 1 billion people worldwide.
  • 16. Some other anthelmintic plants and herbs Ferula asafoetida Embelia ribes Picrasma excelsa Chenopodium ambrosioides Echinacea purpurea Ginkgo biloba Asparagus L. Trifolium repens Ficus insipida Cucurbita maxima Trachyspermum ammi