The liver is the largest internal organ located in the right upper quadrant of the abdomen. It has two surfaces - the diaphragmatic surface and visceral surface. The liver is divided into 8 segments based on the Couinaud classification which describes the functional anatomy and vascular supply. This allows for resection of individual segments without damaging other segments. The segments are delineated by the hepatic veins and portal scissurae into right, left, caudate and quadrate lobes.
Anatomy of urinary bladder. surfaces, border of urinary bladder its relation , ligament support, peritoneal relation in male and females, pouches, blood supply of bladder, nerve supply of bladder, true and false ligament of urinary bladder,
rectus sheath, the sheath covering rectus muscle of anterior abdominal wall, formation of the sheath, the muscles involved in ts formation, and the contents the sheath is covering
This is not a substitute for Books. Let it just help you understand some concepts in liver anatomy.
Continuation of this work will depend on your feedback. Stay Blessed.
Anatomy of urinary bladder. surfaces, border of urinary bladder its relation , ligament support, peritoneal relation in male and females, pouches, blood supply of bladder, nerve supply of bladder, true and false ligament of urinary bladder,
rectus sheath, the sheath covering rectus muscle of anterior abdominal wall, formation of the sheath, the muscles involved in ts formation, and the contents the sheath is covering
This is not a substitute for Books. Let it just help you understand some concepts in liver anatomy.
Continuation of this work will depend on your feedback. Stay Blessed.
The gall bladder is located in the junction of the right ninth costal cartilage and lateral border of the rectus abdominis.
It is a pear shaped sac lying on the inferior surface of the liver in a fossa between the right and quadrate lobes with a capacity of about 30 to 50 mL.
Muscle is a specialized tissue which brings
xThe cells exhibit cross-striations under
functional unit of muscle fiber.
about movement by contraction.
xMuscle tissue is made up of cells called
myocytes. These usually appear as fibers
known as muscle fibers.
xEach muscle fiber is covered by a
membrane known as sarcolemma and a
cytoplasm known as sarcoplasm.
xCytoplasm of each muscle fiber contains
numerous longitudinal threadlike struc
tures called myofibrils, which are made
up of different types of muscle protein
(mainly actin and myosin).
xIt is also rich in mitochondria and
glycogen, which provide energy for it.
xNumerous mitochondria (sarcosomes)
and endoplasmic reticulum (sarcoplasmic
reticulum) are also seen.
Classification of Muscle
Tissue
Based on the appearance of contractile
cells, the muscle tissue is classified as the
following:
xSkeletal/striated/voluntary muscle/
striped muscle.
xCardiac/involuntary muscle.
xSmooth muscle/involuntary/visceral
muscle.
Skeletal Muscle
xSkeletal muscle is attached to bone and
is responsible for movement of axial and
light microscope; hence, it is called stri
ated muscle.
xSkeletal muscles have limited capacity of
regeneration.
Microscopic Structure (Longitudinal
Section) of Skeletal Muscle
xLongitudinal section of skeletal muscles
shows long unbranched cylindrical
muscle fibers running parallel to each
other (Figs.8.1 and 8.2).
xLength of muscle fiber is variable ranging
from few millimeter to many centimeter.
xEach muscle fiber shows multinucleated
flat oval nucleus located peripherally
underneath the sarcolemma.
xMultinucleated appearance of muscle
fiber is due to the fusion of multiple
myoblasts during the embryonic life.
xThe sarcoplasm contains numerous
myofibrils (Fig.8.3).
xUnder light microscope, myofibrils are
seen as dark and light bands.
xThe dark bands are A-bands (anisotropic
under polarized light) and light bands are
I-bands (isotropic under polarized light).
xStriated appearance is mainly due to the
regular arrangement of actin and myosin
myofilaments.
xThe middle of Aband has a light area
known as Hband.
xThe center of H-band has a dark line
known as M-line.
xThe center of I-band is bisected by Z-line.
xThe area between two Z-lines is called
sarcomere, which is the structural and
appendicular skeleton.
anatomy of large intestine all info. is from snell clinical anatomy
this lecture composed of :- cecum , appendix , colon , rectum and anal canal
with all relation (location , blood supply , lymphatic drainage and nerve supply)
This is a slide presentation for MBBS students. a brief overview of hemochromatosis, an iron overload condition. overview of hemochromatosis, pathophysiology, clinical features, approach, and management
Liver transplantation; notes of DM/DNB/SpecialistsPratap Tiwari
Liver transplantation; extensive notes of DM/DNB/Specialists. This was my notes for my exam compiled from several sources, credit goes to original authors. This is just for quick revision
This is a lecture note for 5th-semester MBBS students. Lecture notes on hepatology, liver disease, and liver abscess. Introduction to a liver abscess, pyogenic liver abscess, causes, approach and management of liver abscess.
This is a lecture note for 5th semester MBBS students. Lecture notes on hepatology, liver disease, alcoholic liver disease, alcohol-related liver disease, portal hypertension, hepatic encephalopathy, and acute liver failure. Introduction to acute liver failure, causes, approach, and management of acute liver failure .
This is a lecture note for 5th semester MBBS students. Lecture notes on hepatology, liver disease, alcoholic liver disease, alcohol-related liver disease, portal hypertension, and hepatic encephalopathy. Introduction to hepatic encephalopathy, causes, differentials, approach, and management of hepatic encephalopathy .
This is a lecture note for 5th semester MBBS students. Lecture notes on hepatology, liver disease, alcoholic liver disease, alcohol-related liver disease, alcoholic hepatitis, portal hypertension, ascites. Introduction to ascites and management of ascites.
This is a lecture note for 5th semester MBBS students. Lecture notes on hepatology, liver disease, alcoholic liver disease, alcohol-related liver disease, portal hypertension, ascites. Introduction to ascites and management of ascites.
brief lecture notes for 5th sem MBBS, on portal hypertension and varices. Introduction to portal hypertension and esophageal and gastric varices and management of variceal bleeding.
Chronic liver disease, lecture presentation for 5th sem MBBS students. Introduction to chronic liver disease, notes on liver fibrosis, alcoholic hepatitis, liver histology and overview.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Introduction: Liver
• The liver is largest internal organ & the largest gland in
the human body .
• The normal liver extends from the 5th ICS in the Rt MCL
down to the costal margin.
• It measures 12–15 cm coronally and 15–20 cm
transversely.1
• The median liver weight is 1,800 g in M and 1,400 g in
F.1
1. Wanless I R. Physioanatomic Considerations. In: Schiff ER, Maddrey WC, Sorrell MF, editors. Diseases of the liver.
11th edition. John Wiley & Sons Ltd;2012.
Pic source: http://www.medicinenet.com/drug_induced_liver_disease/article.htm
3. Anatomical Position
and Relations
Anterior to the liver is the anterior abdominal wall ,xiphoid process and ribcage.
Superior to the liver is the diaphragm (separating the abdominal cavity from the
thoracic cavity)
Posterior to the liver are the oesophagus, fundus of stomach, gallbladder, first part
of the duodenum ,hepatic flexure of the colon,right kidney .
Liver lies under the diaphragm in the right upper
quadrant of abdomen and extends to the left upper
quadrant. The liver has the general shape of a
wedge, with its base to the right and its apex to the
left .1
1. Wanless I R. Physioanatomic Considerations. In: Schiff ER,
Maddrey WC, Sorrell MF, editors. Diseases of the liver. 11th
edition. John Wiley & Sons Ltd;2012.
4. Notes of the previous slides
• The abdomen is divided into nine regions by imaginary planes (two vertical and two horizontal) forming
abdominal surface anatomy. The nine regions are of clinical importance when examining and describing
pathologies related to the abdomen. The horizontal planes are of further importance as they provide useful
landmarks on cross sectional imaging.
Horizontal planes
• subcostal plane :corresponds to a line drawn joining the lowermost bony point of the rib cage - usually 10th
costal cartilage
• body of the L3 vertebra; the origin of the inferior mesenteric artery and 3rd part of the duodenum lie on this
plane
transtubercular plane: corresponds to a line uniting the two tubercles of the iliac crests(The iliac tubercle is
located approximately 5 cm (2 in) posterior to the anterior superior iliac spine on the iliac crest in humans.)
• upper border of the L5 vertebra and the confluence of the common iliac veins (i.e. IVC origin) lie on this
plane
Vertical planes
• The two vertical planes are similar on each side and follow a line joining the mid clavicular point to the mid
inguinal point. It passes just lateral to the tip of the ninth costal cartilage - which is palpable as a distinct step
along the costal margin. It roughly corresponds to the lateral border of the rectus abdominis muscle.
5. Liver Surfaces
• The external surfaces of the liver can be classified by the
structures they lie in close proximity to. There are two
liver surfaces – the diaphragmatic and the visceral.
• The diaphragmatic surface refers to the anterosuperior
surface of the liver. It is smooth and convex, fitting snugly
beneath the curvature of the diaphragm. A section of this
surface is not covered by visceral peritoneum, known as the ‘bare area’ of the
liver.
• The visceral surface is the posteroinferior surface related
to the abdominal viscera. It is covered with peritoneum
except for the fossa for the gall bladder and the porta
hepatis. It bears multiple fissures and impressions from
contact with other organs.
7. Peritoneal reflections & bare areas
• The liver is completely surrounded by a fibrous
capsule and covered by peritoneum (except the bare
areas).
• The bare area of the liver is an area of the liver on
the diaphragmatic surface where there is no
intervening peritoneum between the liver and the
diaphragm.
Boundaries of bare area :
• Anterior: superior layer of coronary ligament.
• Posterior: inferior layer of coronary ligament.
• Laterally: right and left triangular ligaments
Other bare areas include porta hepatis; fossa for gall
bladder and grooves for IVC.
8. Fissures
Two sagitally oriented fissures, linked centrally by
the transverse porta hepatis,from the letter H on the
visceral surface.
The left fissure is the continuous groove formed:
• Anteriorly by the fissure for the round ligament.
• Posteriorly by the fissure for the ligamentum
venosum.
The right fissure is the continuous groove formed:
• Anteriorly by the fossa for the gall bladder.
• Posteriorly by the groove for the inferior vena
cava.
9. Porta Hepatis
The cross-bar of the "H" is the porta hepatis, or hilus of the
liver. The limbs of the "H" are
(1) Fissure containing lig teres (obliterated left umbilical vein)
(2) Fissure containing lig. venosum (obliterated ductus
venosus)
(3) the fossa containing the gallbladder
(4) the sulcus in which the inferior vena cava is lodged.
Structures passing through the porta hepatis includes:
• Right and left hepatic ducts
• Right and left branches of hepatic artery.
• Right and left branches of the portal vein
A few hepatic lymph nodes lie here:they drain the liver and
gall bladder and send their efferent vessels to the celiac lymph
nodes.
It also transmits nerves .
Sympathetic Nerves - these provide afferent
pain impulses from the liver and gall bladder to
the brain. Pain may be referred to the lower
pole of the right scapula (T7).
Hepatic branch of the Vagus Nerve (CN X).
10. Liver: ligaments
Coronary ligaments (left/Rt) /
Triangular ligaments (left/Rt) – attach
superior surface of liver to diaphragm.
The anterior and posterior layers
converge on the rt & lt sides of the liver
to form the rt triangular lig and left
triangular lig, respectively.
In between the two sides of the anterior layer, the reflection of
peritoneum has an inferior continuation termed the falciform ligament.
Falciform ligament – attaches the anterior surface of the
liver to the ant abdominal wall. The free edge of this
ligament contains the ligamentum teres(remnant of the UV).
11. Liver: ligaments
Hepatogastric lig/gastrohepatic ligament connects
the liver to the lesser curvature of the stomach.
It contains the right and the left gastric arteries.
The hepatoduodenal ligament is
the portion of the lesser
omentum extending between
the porta hepatis & superior part
of the duodenum.
It sheathes the hepatic artery (HA), portal
vein (PV), nerves, bile duct, and lymph
vessels, all present within the porta hepatis.
In the ligament the common bile duct lies to
the right, the HA to the left, and the PV
behind them.
Manual compression of the hepatoduodenal
ligament during surgery is known as the Pringle
Maneuver.
12. Hepatic Recesses
• The hepatic recesses: spaces between the liver and
surrounding structures. They are of clinical importance,
as infected fluids can collect in these areas, forming an
abscess.
• Subphrenic spaces (left and right) – located between
the diaphragm and liver, either side of the falciform
ligament.
• Subhepatic space – located between the inferior
surface of the liver and the transverse colon.
• Morison’s pouch – the posterosuperior aspect of the
right subhepatic space, located between the visceral
surface of the liver and the right kidney. This is the deepest
part of the peritoneal cavity when supine (lying flat), and this is where fluid
is likely to collect in a bedridden patient.
13. Left subphrenic space
Left perihepatic space
Posterior rt subhepatic space
Ant rt Subhepatic space
Rt Subphrenic space
Rt Subhepatic space
Right SMCS Left SMCS
Inframesocolic spaceSupramesocolic space
Post left perihepatic space
Ant Left perihepatic space
Ant Left subphrenic space
Post Left subphrenic (perisplenic
) space
Transverse solon
Not shown
The PRSHS (AKA the hepatorenal fossa or Morison's pouch) separates the liver
from the right kidney.This is the deepest part of the peritoneal cavity when supine
(lying flat), and this is where fluid is likely to collect in a bedridden patient.
Reference: Standring S (editor). Gray's Anatomy (39th edition). Churchill Livingstone. (2011)
14. Lobes of liver
• The lobes of the liver can be described using two different aspects:
morphological anatomy & functional anatomy.
• The traditional morphological anatomy is based on the external appearance
of the liver and does not show the internal features of vessels and biliary
ducts branching, which are of obvious importance in hepatic surgery.
• The entire liver is covered by a fibrous layer, known as Glisson’s
capsule(orWalaeus). (Named for the British physician, anatomist,
physiologist, and pathologist Francis Glisson (1597-1677).
• With reference to the attachment of the falciform ligament on the
diaphragmatic surface of liver, Liver is divided into a right lobe and left lobe.
• On the visceral surface, there are two further ‘accessory’ lobes The caudate
and quadrate lobes which are classified with the right anatomical lobe of the
liver.
15. Lobes of liver
• The caudate lobe is located on the upper aspect of the
visceral surface. The caudate lobe of the liver is bounded
below, by the porta hepatis; on the right, by the fossa for
the inferior vena cava; and, on the left, a fossa produced
by the ligamentum venosum .
• The caudate lobe is named after the tail-shaped hepatic tissue (cauda; Latin, "tail") caudate process
of the liver, which provides surface continuity between the caudate lobe and the visceral surface of
the right lobe of the liver.
• The quadrate lobe is located on the lower aspect of the visceral surface. It lies
between the gallbladder and a fossa produced by the ligamentum teres (a
remnant of the fetal umbilical vein).
• Between the caudate and quadrate lobes is a deep fissure, known as the porta hepatis. It transmits all the
vessels, nerves and ducts entering or leaving the liver.
17. Note to the previous slides
The French surgeon and anatomist Claude Couinaud :1957(1922-2008) was the first to divide the liver into eight
functionally independant segments allowing resection of segments without damaging other segments. And thus The
Couinaud classification (pronounced kwee-NO) is used to describe functional liver anatomy.
The segments are numbered in roman numerals I to VIII.
The delineation of the segments is based on the fact that each segment has its own dual vascular inflow, outflow,
biliary drainage and lymphatic drainage. In general each segment can be thought of as wedged shaped with the apex
directed towards the hepatic hilum (porta hepatis). At the apex a single segmental branch of the portal vein, hepatic
artery and bile duct enter; whereas along the sides of each segment there is venous outflow through the hepatic
veins so that a hepatic vein drains two adjacent segments.
These veins run in 3 vertical planes that separate the segments:
1. right hepatic vein located in the right intersegmental fissure, divides the right lobe into anterior and posterior
parts
2. middle hepatic vein lies in the main lobar fissure, divides the liver into right and left lobes (or right and left
hemiliver): this vertical plane runs from the inferior vena cava to the gallbladder fossa and is known as Cantlie's
line . The Falciform ligament divides the left lobe into a medial- segment IV and a lateral part - segment II and III.
3. left hepatic vein located in the left intersegmental fissure, divides the left lobe into medial and lateral parts
A horizontal plane further divides the liver, known as the portal plane where the portal vein bifurcates and becomes
horizontal, dividing the liver into superior and inferior units.
These 4 planes (3 vertical and 1 horizontal) divide the liver into the 8 segments.
18. Note to the previous slides
Segments
• segments II and III are to the left of the left hepatic vein and falciform ligament
with II superior and III inferior to the portal plane
• segment IV lies between the left and middle hepatic veins; it is subdivided into
IVa (superior) and IVb (inferior) subsegments
• segment IV includes the quadrate lobe
• Segment V to VIII make up the right hemiliver and are easier to describe:
• segment V is located below the portal plane between the middle and right
hepatic veins
• segment VI is located below the portal plane to the right of the right hepatic vein
• segment VII is located above the portal plane to the right of the right hepatic vein
• segment VIII is located above the portal plane between the middle and right
hepatic veins
19. Couinaud classification
The right border of the liver is formed by segment V and VIII.
Although segment IV is part of the left hemiliver, it is situated more to the right.
Couinaud divided the liver into a functional left and right liver by a main portal scissurae containing the middle
hepatic vein. This is known as Cantlie's line.
Cantlie's line runs from the middle of the gallbladder fossa anteriorly to the inferior vena cava posteriorly.
20. Separating liver segments on CS imaging
Left lobe: lateral(II/III) vs medial segment (IVA/B)
Extrapolate a line along the falciform ligament superiorly to
the confluence of the left and middle hepatic veins at the
IVC (blue line).
Left vs Right lobe: IVA/B vs V/VIII
Extrapolate a line from the gallbladder fossa superiorly
along the middle hepatic vein to the IVC (red line).
Right lobe: anterior (V/VIII) vs posterior segment (VI/VII)
Extrapolate a line along the right hepatic vein from the IVC
inferiorly to the lateral liver margin (green line).
Ref: http://www.radiologyassistant.nl/en/p4375bb8dc241d/anatomy-of-the-liver-segments.html
21. Extra note
Hypertrophy of the caudate lobe is seen in a number of conditions,
including:
• cirrhosis : most common
• Budd-Chiari syndrome
• primary sclerosing cholangitis (PSC) (end stage)
• congenital hepatic fibrosis
• cavernous transformation of the portal vein
22. Transverse section
This is a transverse image at the level of the left portal vein.
At this level the left portal vein divides the left lobe into the superior
segments (II and IVa) and the inferior segments (III and IVb).
The left portal vein is at a higher level than the right portal vein.
This figure is a transverse image through the superior
liver segments, that are divided by the right and
middle hepatic veins and the falciform ligament.
23. Transverse section
This image is at the level of the right portal vein.
At this level the right portal vein divides the right lobe of
the liver into superior segments (VII and VIII) and the
inferior segments (V and VI).
The level of the right portal vein is inferior to the level of
the left portal vein.
At the level of the splenic vein, which is below the
level of the right portal vein, only the inferior
segments are visible.
24. Caudate lobe
• The caudate lobe or segment I is
located posteriorly.
• The caudate lobe is anatomically
different from other lobes in that it
often has direct connections to the
IVC through hepatic veins, that are
separate from the main hepatic veins.
• The caudate lobe may be supplied by
both right and left branches of the
portal vein.
This CT-image is of a patient with liver cirrhosis with extreme atrophy of the right lobe, normal volume of the left lobe and
hypertrophy of the caudate lobe.
Due to a different blood supply the caudate lobe is spared from the disease process and hypertrophied to compensate for the
loss of normal liver parenchyma.
25. Surgical point of view
Right hepatectomy
segment V, VI, VII and VIII (± segment I).
Extended Right or right trisectionectomy
segment IV, V, VI, VII and VIII (± segment I).
Left hepatectomy
segment II, III and IV (± segment I).
Extended Left or left trisectionectomy
segment II, III, IV, V and VIII (± segment I).
Ref: http://www.radiologyassistant.nl/en/p4375bb8dc241d/anatomy-of-the-liver-segments.html
26. Surgical point of view
Right posterior sectionectomy
segment VI and VII
Right anterior sectionectomy
segment V and VIII
Left medial sectionectomy
segment IV
Left lateral sectionectomy
segment II and III
Ref: http://www.radiologyassistant.nl/en/p4375bb8dc241d/anatomy-of-the-liver-segments.html
27. Surface marking
• The upper border of the right lobe is on a level with the
5th rib at a point 2 cm medial to the right
midclavicular line (1 cm below the right nipple).
• The upper border of the left lobe corresponds to the
upper border of the 6th rib at a point in the left
midclavicular line (2 cm below the left nipple).
• The lower border passes obliquely upwards from the
9th rib to the 8th left costal cartilage. It crosses the
midline about midway between the base of the xiphoid
and the umbilicus and the left lobe extends only 5 cm
to the left of the sternum.
28. Next : circulation & collaterals
References:
Henryk clinical hepatology
Schiff’s diseases of the liver
Sherlock's Diseases of the Liver and Biliary System
Editor's Notes
The abdomen is divided into nine regions by imaginary planes (two vertical and two horizontal) forming abdominal surface anatomy. The nine regions are of clinical importance when examining and describing pathologies related to the abdomen. The horizontal planes are of further importance as they provide useful landmarks on cross sectional imaging.
Horizontal planes
The dividing planes are based on lines drawn between easily palpable bony points. The two horizontal lines are:
subcostal plane
corresponds to a line drawn joining the lowermost bony point of the rib cage - usually 10th costal cartilage
body of the L3 vertebra; the origin of the inferior mesenteric artery and 3rd part of the duodenum lie on this plane
transtubercular plane
corresponds to a line uniting the two tubercles of the iliac crests(The iliac tubercle is located approximately 5 cm (2 in) posterior to the anterior superior iliac spine on the iliac crest in humans.)
upper border of the L5 vertebra and the confluence of the common iliac veins (i.e. IVC origin) lie on this plane
Vertical planes
The two vertical planes are similar on each side and follow a line joining the mid clavicular point to the mid inguinal point. It passes just lateral to the tip of the ninth costal cartilage - which is palpable as a distinct step along the costal margin. It roughly corresponds to the lateral border of the rectus abdominis muscle.