The document provides an overview of the anatomy of the spine. It discusses the conceptual overview including the functions and components of the spine. It describes the regional anatomy including the intervertebral discs, ligaments, muscles and fascia of the back. It also discusses the blood supply, lymph drainage and surface anatomy as it relates to the spine. Key features include the long vertebral column and short spinal cord, as well as the intervertebral foramina and spinal nerves.
The fascial compartments of thigh are the three fascial compartments that divide and contain the thigh muscles. The fascia lata is the strong and deep fascia of the thigh that surrounds the thigh muscles and forms the outer limits of the compartments. Internally the muscle compartments are divided by the lateral and medial intermuscular septa.
elbow joint , type of joint, articular surface of elbow joint, joint capsule of elbow joint, articulating bones of elbow joint, cubital articulation, ligaments of the elbow joint, medial collateral ligament, lateral collateral ligament, relation of elbow joint, action of elbow joint, blood supply and nerve supply of elbow joint, dislocation of elbow joint, carrying angle, cubital varus, cubital vulgus, subluxation of head of radius, tennis elbow, students or minors elbow,
The fascial compartments of thigh are the three fascial compartments that divide and contain the thigh muscles. The fascia lata is the strong and deep fascia of the thigh that surrounds the thigh muscles and forms the outer limits of the compartments. Internally the muscle compartments are divided by the lateral and medial intermuscular septa.
elbow joint , type of joint, articular surface of elbow joint, joint capsule of elbow joint, articulating bones of elbow joint, cubital articulation, ligaments of the elbow joint, medial collateral ligament, lateral collateral ligament, relation of elbow joint, action of elbow joint, blood supply and nerve supply of elbow joint, dislocation of elbow joint, carrying angle, cubital varus, cubital vulgus, subluxation of head of radius, tennis elbow, students or minors elbow,
Schmorl’s nodes (SN) or Intervertebral Disc Herniations are Commonly observed on routine radiographs at autopsy.
This is a teaching lecture given by Prof. Dr. Mohamed Mohi Eldin, professor of neurosurgery, in the weekly conference of kasr El Aini Neurosurgery Department, Cairo University, November 2010.
Case Review #8: 62 year old female with cervical spinal stenosisRobert Pashman
62 year old female with neck pain and left arm weakness. On MRI, the patient was found to have spinal stenosis. Dr. Pashman treated the patient with an Anterior Cervical Discecomy and fusion C4-/7.
USMLE RESP 05 thoracic wall anatomy medical chest .pdfAHMED ASHOUR
The thoracic wall refers to the skeletal and muscular structures that form the outer boundary of the thoracic cavity, providing protection to the organs within the chest in addition to running vessels and nerves.
The thoracic wall plays a crucial role in protecting the vital organs of the chest, including the heart and lungs. The coordinated action of the ribs, sternum, muscles, and diaphragm allows for the expansion and contraction of the thoracic cavity during respiration. The bony and muscular structures also contribute to the overall stability and integrity of the chest region.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
3. Conceptual overviewConceptual overview
Functions
Support
Movement <additive>
Protection of central & peri nervous systems
flexion
extension
lateral flexion
rotation, and
circumduction
4. curvescurves
Sec curvature bring the center
of gravity to a vertical line,
which allows the body’s weight
to be balanced on the vertebral
column in a way that expends
the least amount of muscular
energy to maintain an
upright bipedal stance.
11. LigamentsLigaments
Supraspinous This runs between the tips of adjacent spines.
Interspinous : This connects adjacent spines.
Intertransverse: These run between adjacent transverse processes.
Ligamentum flavum : This connects the laminae of adjacent vertebrae.
cervical region= supraspinous and interspinous ligaments greatly
thickened to form the strong ligamentum nuchae.
13. Dislocations and fractures of
the vertebral column.
A. Unilateral dislocation of the fifth or the
sixth cervical vertebra. Note the forward
displacement of the inferior articular
process over the superior articular process
of the vertebra below. B. Bilateral
dislocation of the fifth or the sixth
cervical vertebra. Note that 50% of
the vertebral body width has moved
forward on the vertebra below. C.
Flexion compression–type fracture
of the vertebral body in the lumbar
region. D. Jefferson's-type
fracture of the atlas. E.
Fractures of the odontoid
process and the pedicles
(hangman's fracture) of the
axis.
14. A. Arrangement of theA. Arrangement of the
deep muscles of thedeep muscles of the
back. B. Lateral view ofback. B. Lateral view of
the skeleton showingthe skeleton showing
the line of gravity.the line of gravity.
Because the greater part of theBecause the greater part of the
body weight lies anterior tobody weight lies anterior to
the vertebral column, the deepthe vertebral column, the deep
muscles of the back aremuscles of the back are
important in maintaining theimportant in maintaining the
normal postural curves of thenormal postural curves of the
vertebral column in thevertebral column in the
standing position.standing position.
15. MusclesMuscles
Trap, Lat dorsi, Lev scap, Rho maj & min
Serratus posterior sup & inf
Deep
Superficial Vertically Running Muscles
Intermediate Oblique Running Muscles
Deepest Muscles
Interspinales
Intertransversarii
16.
17.
18. Muscular triangles of backMuscular triangles of back
Auscultatory Triangle
The auscultatory triangle is the site on the back where breath
sounds may be most easily heard with a stethoscope. The
boundaries are the latissimus dorsi, the trapezius, and the medial
border of the scapula.
Lumbar Triangle
The lumbar triangle is the site where pus may emerge from the
abdominal wall. The boundaries are the latissimus dorsi, the
posterior border of the external oblique muscle of the abdomen,
and the iliac crest.
19. Deep Fascia of the BackDeep Fascia of the Back
(Thoracolumbar Fascia)(Thoracolumbar Fascia)
The lumbar part of the deep fascia is situated in the interval between
the iliac crest and the 12th rib. It forms a strong aponeurosis and
laterally gives origin to the middle fibers of the transversus and the
upper fibers of the internal oblique muscles of the abdominal wall
Medially, the lumbar part of the deep fascia splits into three lamellae.
The posterior lamella covers the deep muscles of the back and is
attached to the lumbar spines. The middle lamella passes medially, to
be attached to the tips of the transverse processes of the lumbar
vertebrae; it lies in front of the deep muscles of the back and behind
the quadratus lumborum. The anterior lamella passes medially and is
attached to the anterior surface of the transverse processes of the
lumbar vertebrae; it lies in front of the quadratus lumborum muscle.
20. Blood Supply of the BackBlood Supply of the Back
Arteries
◦ In the cervical region, branches arise from the occipital artery, a branch
of the external carotid; from the vertebral artery, a branch of the
subclavian; and from the deep cervical artery, a branch of the
costocervical trunk.
◦ In the thoracic region branches arise from the posterior intercostal
arteries.
◦ In the lumbar region branches arise from the subcostal and lumbar
arteries.
◦ In the sacral region branches arise from the iliolumbar and lateral sacral
arteries, branches of the internal iliac artery.
Veins
◦ The veins draining the structures of the back form plexuses extending
along the vertebral column from the skull to the coccyx.
◦ The external vertebral venous plexus lies external and surrounds the
vertebral column.
◦ The internal vertebral venous plexus lies within the vertebral canal but
outside the dura mater of the spinal cord.
21. Lymph Drainage of the BackLymph Drainage of the Back
The deep lymph vessels follow the veins and drain into the deep
cervical, posterior mediastinal, lateral aortic, and sacral nodes.
The lymph vessels from the skin of the neck drain into the
cervical nodes,
from the trunk above the iliac crests drain into the axillary
nodes, and those
from below the level of the iliac crests drain into the superficial
inguinal nodes
22. RelationRelation
Vertebrae Spinal Segment
Cervical Add 1
Upper thoracic Add 2
Lower thoracic (T7 to 9) Add 3
Tenth thoracic L1 and 2 cord segments
Eleventh thoracic L3 and 4 cord segments
Twelfth thoracic L5 cord segment
First lumbar Sacral and coccygeal cord segment
23. Posterior views of vertebral bodies in the
cervical and lumbar regions showing the
relationship that might exist between the
herniated nucleus pulposus and the spinal
nerve roots. Note that there are eight cervical
spinal nerves but only seven cervical
vertebrae. In the lumbar region, for example,
the emerging L4 nerve roots pass out laterally
close to the pedicle of the fourth lumbar
vertebra and are not related to the
intervertebral disc between the fourth and
fifth lumbar vertebrae. E. Pressure on the L5
motor nerve root produces weakness of
dorsiflexion of the ankle; pressure on the S1
motor nerve root produces weakness of plantar
flexion of the ankle joint.
24. SPINAL CORD INJURY WITHOUT RADIOLOGICAL ABNORMALITY:
‘SCIWORA’
This is particularly liable to occur if the vertebral canal is
abnormally narrowed, usually by osteoarthritic changes.
Formation and branching pattern of a typical spinal nerve
Formation and branching pattern of a typical spinal nerve
Joints in the cervical, thoracic, and lumbar regions of the vertebral column. B. Third lumbar vertebra seen from above showing the relationship between intervertebral disc and cauda equina. C. Sagittal section through three lumbar vertebrae showing ligaments and intervertebral discs. Note the relationship between the emerging spinal nerve in an intervertebral foramen and the intervertebral disc.
C. Posterolateral herniation of the nucleus pulposus of the intervertebral disc between the fifth lumbar vertebra and the first sacral vertebra showing pressure on the S1 nerve root. D. An intervertebral disc that has herniated its nucleus pulposus posteriorly.
This is particularly liable to occur if the vertebral canal is abnormally narrowed, usually by osteoarthritic changes