2.  Achlorhydria
is the absence of hydrochloric
acid in the gastric secretions. Patient with
this condition fall into two groups.
 01.
Free of gastric hydrochloric acid after
stimulating with histamine phosphate.
 02. lack of gastric hydrochloric but respond
to stimulation by histamine.

3.  The
symptoms of acklorhydria can vary with
the associated disease. These includes
 01. Mild diarrhea
 02.Epigastric pain
 03. Sensitivity to spicy food
 04. pernicious anaemia

4.  Pepsin
possesses it’s greatest proteolytic
activity below pH 3.5. In achlorhydria there
is absense of hydrochloric acid in stomach.

So pH is not maintain in desired level and
pepsin is inactivated. As a result the above
symptom arrived.

5.  It
is common for patients with achlorhydria
to have pernicious anaemia due to lake of
intrinsic factor, the protein necessary to
carry vitamin B12 across the intestinal wall.

6.  Patients
of the first type fall into the
complications of
 01. Subtotal gastrectomy
 02. Atrophic gastritis
 03. Carcinoma of stomach
 04. Gastric polyps

7.  Patients
of the second type fall into the
complication of
 01. Chronic nephritis
 02. chronic alcoholism
 03. Tuberculosis
 04. Hyperthyroidism
 05. pellagra
 06 Sprue
 07. parasitic infestation

8.  Treatment/Remedy
of Achlorhydria:
 5 ml dilute HCL N.F in 200 ml water required
to treat achlorhydria. It provides about 15
meq of acid.
 Note:
Dilute HCL means it will contain not
less than 9.5 gm and not more than 10.5 gm
in each 100 ml solution.

9.  Natural
remedies for achlorhydria:
 Batter herbs
 Betain hydrochloride
 Chew throwly
 Vitamin B complex
 Glutamine
 Ginger tea

10.  In
order to avoid exposure of dental enamel
of HCL, the use of straw laid well back on
toungue has been recommended or the use
of equivalent product such as glutamic acid,
HCL. Which is administered in capsules.

11. Little is known on the prognosis of
achlorhydria, although there have been reports
of gastric cancer.

12. 
Thanks to all