Paracentesis is a procedure to remove fluid from the peritoneal cavity for diagnostic and therapeutic purposes. Large amounts of ascites fluid can cause respiratory compromise by exerting pressure on the diaphragm and abdominal organs. Paracentesis relieves this pressure and improves breathing. Key steps include ultrasound assessment, local anesthesia, inserting a needle into the abdomen, draining fluid, and analyzing laboratory samples of the fluid. Complications may include infection, bleeding, or organ damage.
Thoracentesis is a procedure in which a needle is inserted into the pleural space between the lungs and the chest wall. This procedure is done to remove excess fluid, known as a pleural effusion, from the pleural space to help you breathe easier.
Thoracentesis is a procedure in which a needle is inserted into the pleural space between the lungs and the chest wall. This procedure is done to remove excess fluid, known as a pleural effusion, from the pleural space to help you breathe easier.
It is a procedure where small piece of liver tissue is removed and examined to Confirm clinical diagnosis, and assess the severity, and progression treatment response of the disease.
Colonoscopy is a procedure used to see
inside the colon and rectum. Colonoscopy can detect inflamed tissue, ulcers,
and abnormal growths. The procedure is used to look for early signs of
colorectal cancer and can help doctors diagnose unexplained changes in bowel
habits, abdominal pain, bleeding from the anus, and weight loss.
NIDDK
IV Cannulation Introducing a single dose of concentrated medication directly...ssuser3155141
Introducing a single dose of concentrated medication directly into the systemic circulation
“Or”
The introduction of a large amount of fluid & electrolytes and other nutrients into the body via veins.
It is a procedure where small piece of liver tissue is removed and examined to Confirm clinical diagnosis, and assess the severity, and progression treatment response of the disease.
Colonoscopy is a procedure used to see
inside the colon and rectum. Colonoscopy can detect inflamed tissue, ulcers,
and abnormal growths. The procedure is used to look for early signs of
colorectal cancer and can help doctors diagnose unexplained changes in bowel
habits, abdominal pain, bleeding from the anus, and weight loss.
NIDDK
IV Cannulation Introducing a single dose of concentrated medication directly...ssuser3155141
Introducing a single dose of concentrated medication directly into the systemic circulation
“Or”
The introduction of a large amount of fluid & electrolytes and other nutrients into the body via veins.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Couples presenting to the infertility clinic- Do they really have infertility...
Abdominal paracentesis
1.
2. The accumulation of large amount of fluid within
the peritoneal cavity exerts pressure on the
diaphragm and abdominal organs and
vasculature, leading to respiratory compromise
and increased work of breathing. Paracentesis
relieves intra abdominal and diaphragmatic
pressures, diminishing the work of breathing.
3. “ Paracentesis is a procedure in which
fluid is removed from the peritoneal cavity for
diagnostic and therapeutic purposes.”
4. 1.To obtain fluid samples from the peritoneal
space for diagnostic examination.
2. Evacuate fluid from the peritoneal space.
3. Alleviate respiratory compromise related to
pressure on the diaphragm caused by ascetic
fluid.
5.
6. New onset ascites or ascites of
unknown origin.
Patient with a known ascites who has
fever, abdominal pain, hypotension or
encephalopathy.
Symptomatic treatment of large
ascites.
7. × Uncooperative patients
× Uncorrected bleeding diathesis
× Acute abdomen that requires surgery
× Intra-abdominal adhesions
× Distended bowel
× Abdominal wall cellulitis at the site of puncture
× Pregnancy
12. 1. Ultrasound scan before
the procedure
2. Patient preparation
3. Procedure
4. Laboratory results
13. What is the distance from the skin to
the fluid?
Usually 1 cm. It gives an idea how
deep you have to go with the needle
before getting fluid in the syringe.
14. Explain the rba (risks, benefits,
alternatives)
Informed written consent urinate before
the procedure or use a folley’s to empty
the bladder.
Position the patient in the bed with the
head elevated at 45-60 degrees to allow
fluid to accumulate in lower abdomen.
15. Position the patient in the bed with the head
elevated at 45-60 degrees
To allow fluid to
Accumulate
in lower abdomen.
16.
17. 2 cms below the umbilicus in the midline
(through the linea alba)
5 cms superior and medial to the anterior
superior iliac spines on either side.
18. Position the patient and prepare the skin
around the entry site with an antiseptic
solution .
20. 4-5 mL of lidocaine along the catheter
insertion tract,anesthetise
all the way down to the peritoneum.
21. Use the No. 11 scalpel blade to
make a small nick in the skin to
allow an easier catheter
passage.
22. Insert the needle directly
perpendicular to the
selected skin entry point.
Continuously apply negative
pressure to the syringe as
the needle is advanced.
Upon entry to the peritoneal
cavity, loss of resistance is felt
and ascitis fluid can be seen filling
the syringe.
23. Use one hand to firmly
anchor the needle and
syringe securely in place to
prevent the needle from entering
further the peritoneal cavity
Stabilization of needle
and syringe
24. While holding the stopcock, pull
the needle out.
Attach the 50-ml syringe to the
3-way stopcock and aspirate to
obtain ascitis fluid.
25.
26. Connect one end of the fluid
collection tubing to the stopcock
and the other end to a vacuum
bottle or a drainage bag .
27.
28. Consent
Indications and contraindications
for procedure
Procedure, including prep,
anesthetic, needle size, amount of
fluid drawn off, character of fluid
Any complications or “none”
Who was notified of any
complication (family, attending MD)
30. Fluid specimen for laboratory analysis.
Record amount ,characteristics of fluid ,
number of specimens sent to laboratory.
Patient’s condition during treatment
31. Check vital signs every half hour for two
hours, every hour for four hours and every
four hour for 24 hours.
Watch for leakage or scrotal edema after
paracentesis.
Observe the site for bleeding
Replace the articles
32.
33. Gram stain (bacterial peritonitis.)
Cell count (elevated counts may
suggest infection)
Bacterial culture
Total protein level
Triglyceride levels (elevated in
chylous ascites)
Bilirubin level (may be elevated in
bowel perforation)
Glucose level
Amylase level (elevation suggests
pancreatic source)
34.
35. Perforation of bowel or bladder.
Local or systemic infection.
Hypovolemia, hypotension.
Bleeding from paracentesis site.
Ascetic leak from paracentesis site.