The document discusses using wavelet time-frequency analysis to analyze transient evoked otoacoustic emissions (TEOAEs) in order to accurately estimate the relationship between TEOAE latency and cochlear frequency tuning. One-dimensional transmission line cochlear models predict that the TEOAE latency-frequency relation depends on whether or not scale-invariance holds in the cochlea. The latency of a given frequency component can be separated into parts, one of which depends on cochlear quality factor Q(f), allowing an objective estimate of cochlear tuning. Coherent reflection filtering theory relates the spontaneous otoacoustic emission (SOAE) minimum spacing to cochlear tuning as measured by Q
Stability of Target Resonance Modes: Ina Quadrature Polarization ContextIJERA Editor
The paper present a studyon the noise effect whenextracting the resonance residue in a quadrature polarization
setup. The accuracy and stability of the mode quadrature residues is necessary to construct the polarization matrix,
and subsequently, derive a robust polarization states of the receiver antenna. However, with lower signal-to-noise
ratios the extraction performance will degrade; in this regards, the in-phase and quadrature components of the
baseband signal demonstrated improvedextraction performancewhen used. Here, a case of two disjoint wires is
used to verify this approach.
On Fractional Fourier Transform Moments Based On Ambiguity FunctionCSCJournals
The fractional Fourier transform can be considered as a rotated standard Fourier transform in general and its benefit in signal processing is growing to be known more. Noise removing is one application that fractional Fourier transform can do well if the signal dilation is perfectly known. In this paper, we have computed the first and second order of moments of fractional Fourier transform according to the ambiguity function exactly. In addition we have derived some relations between time and spectral moments with those obtained in fractional domain. We will prove that the first moment in fractional Fourier transform can also be considered as a rotated the time and frequency gravity in general. For more satisfaction, we choose five different types signals and obtain analytically their fractional Fourier transform and the first and second-order moments in time and frequency and fractional domains as well.
Stability of Target Resonance Modes: Ina Quadrature Polarization ContextIJERA Editor
The paper present a studyon the noise effect whenextracting the resonance residue in a quadrature polarization
setup. The accuracy and stability of the mode quadrature residues is necessary to construct the polarization matrix,
and subsequently, derive a robust polarization states of the receiver antenna. However, with lower signal-to-noise
ratios the extraction performance will degrade; in this regards, the in-phase and quadrature components of the
baseband signal demonstrated improvedextraction performancewhen used. Here, a case of two disjoint wires is
used to verify this approach.
On Fractional Fourier Transform Moments Based On Ambiguity FunctionCSCJournals
The fractional Fourier transform can be considered as a rotated standard Fourier transform in general and its benefit in signal processing is growing to be known more. Noise removing is one application that fractional Fourier transform can do well if the signal dilation is perfectly known. In this paper, we have computed the first and second order of moments of fractional Fourier transform according to the ambiguity function exactly. In addition we have derived some relations between time and spectral moments with those obtained in fractional domain. We will prove that the first moment in fractional Fourier transform can also be considered as a rotated the time and frequency gravity in general. For more satisfaction, we choose five different types signals and obtain analytically their fractional Fourier transform and the first and second-order moments in time and frequency and fractional domains as well.
Frequency and Power Estimator for Digital Receivers in Doppler Shift Environm...CSCJournals
A frequency estimator well suited for digital receivers is proposed. Accurate estimates of unknown frequency and power of input sinusoidal signal, in the presence of additive white Gaussian noise (AWGN), are provided. The proposed structure solve the problems of traditional phase locked loop (PLL) such as, narrow tracking range, overshoot, long settle time, double frequency ripples in the loop and stability. Proposed method can estimate frequencies up to half the sampling frequency irrespective of the input signal power. Furthermore, it provides stability and allows fast tracking for any changes in input frequency. The estimator is also implemented using field programmable gate array (FPGA), consumes 127 mW and works at a frequency of 225 MHz. Proposed method can estimate the fluctuation in frequency of transmitter’s oscillator, can be used as a frequency shift keying receiver and can also be applied as a digital receiver in Doppler shift environment.
Accurate Evaluation of Interharmonics of a Six Pulse, Full Wave - Three Phase...idescitation
Interharmonics are the non-integral multiples of
the system’s fundamental frequency. The interharmonic
components can be apprehended as the intermodulation of
the fundamental and harmonic components of the system with
any other frequency components introduced by the load. These
loads include static frequency converters, cyclo-converters,
induction motors, arc furnaces and all the loads not pulsating
synchronously with the fundamental frequency of the system.
The harmonic and interharmonic components inflict common
damage to the system and apart from these damages the
interharmonics also cause light flickering, sideband torques
on motor/generator and adverse effects on transformer and
motor components. To
filter/compensate the interharmonic
components, their accurate evaluation is essential and to
achieve the same the Iterative algorithm has been proposed.
The main cause of spectral leakage errors is the truncation of
the time-domain signal. The proposed adaptive approach
calculates the immaculate window width, eliminating the
spectral leakage errors in the frequency domain and thereby
the interharmonics/harmonics can be calculated accurately.
The algorithm does not require any inputs regarding the
system frequency and interharmonic constituents of the
system. The only parameter required is the signal sequence
obtained by sampling the analog signal at equidistant sampling
interval.
Packets Wavelets and Stockwell Transform Analysis of Femoral Doppler Ultrasou...IJECEIAES
Ultrasonic Doppler signals are widely used in the detection of cardiovascular pathologies or the evaluation of the degree of stenosis in the femoral arteries. The presence of stenosis can be indicated by disturbing the blood flow in the femoral arteries, causing spectral broadening of the Doppler signal. To analyze these types of signals and determine stenosis index, a number of time-frequency methods have been developed, such as the short-time Fourier transform, the continuous wavelets transform, the wavelet packet transform, and the S-transform
The main advantage of wavelet transforms are
1. Wavelet transforms has multiresolution properity
2. Better Spectral localization properity
What is Multiresolution properity:
Multiresolution properity means that wavelet transform used different Scales for the analysis of different frequency componants of any signal .
What is scale:
Scale is inversely propertional to the frequency of any signal
large scale is used for the analysis of small frequency componants presents in any signal Whereas Small scale is used for the analysis of high frequency componants of any signal
What is Spectral localisation
Spectral localization properity means that wavelet transform tells us that what frequency componants are present in any given signal and at time axis where these frequency componants are presents
Process of taking Wavelet transform of any signal
Simulation of Nonstationary Processes in Backward-Wave Tube with the Self-Mod...Victor Solntsev
The equations that describe nonlinear nonstationary processes in carcinotrode (backward- wave tube with the emission modulation in the presence of the field of the output signal fed to the cathode via a feedback loop) are derived. An algorithm and the corresponding code are developed to solve the equations with allowance for the modulation of emission using nonuniform (with respect to time) large particles (electrons of equal charge) ejected from the cathode. The effect of the feedback parameter on the intensity and shape of the carcinotrode oscillations is analyzed. It is demonstrated that the carcinotrode efficiency can be increased to about 50% upon the generation of harmonic oscil- lations. A more significant increase in the efficiency to 70% is possible in the regime of the weak self- modulation of oscillations upon an increase in the feedback coefficient in the feedback loop involving the slow-wave structure and the cathode and a decrease in the cathode–grid static field.
A JOINT TIMING OFFSET AND CHANNEL ESTIMATION USING FRACTIONAL FOURIER TRANSFO...IJCNCJournal
This paper deals with symbol timing offset and channel estimation in OFDM (orthogonal frequency
division multiplexing) system in fast varying channel. Symbol timing offset (STO) estimation is a major task
in OFDM. Most of existing methods for estimating STO used cyclic prefix or training sequences. In this
paper, we consider a new system for STO estimation using constant amplitude zero autocorrelation
(CAZAC) sequences as pilot sequences in conjunction with fractional Fourier transform (FRFT). After STO
estimation is done, timing compensation is made. Thereafter, channel is estimated to well recover the
original transmitted signal. This method gives good results in terms of MSE in comparison with other
known techniques, it estimated well the channel and it is important for fast varying channel. MATLAB
Monte-Carlo simulations are used to evaluate the performance of the proposed estimator.
In [4], we have studied the statistical properties
and mono-fractality of the power system time series,
voltage magnitude (V ), frequency (f), and phase angle
(). The power system data was measured using three
Phasor Measurement Units (PMUs) installed at Baylor
University, Harris Substation, McDonald Observatory in
the Texas Synchrophasor Network [1]. Our analysis of
several data sets has shown that the three time series
are non-stationary. Moreover, we provided an evidence to
the existence of long-range memory in the power system
data with scaling exponents higher than 0.5. The scaling
exponents of voltage magnitude (V ), frequency (f), and
phase angle () were approximately equal to 1, 1.5, and
0.7, respectively.
Our first goal is to analyze more data sets using
the Detrended Fluctuation Analysis (DFA) method
to support our conclusions regarding the existence of
long-range memory in the power grid time series. In
our analysis, we apply the DFA method on data sets
collected on PMUs installed in the École Polytechnique
Fédérale de Lausanne (EPFL) campus in Lausanne,
Switzerland [2]. The results show a consistency between
the scaling exponents values calculated using the data
from the Texas Synchrophasor Network and the data
from the EPFL campus.
Secondly, we study the fractal dimension behavior of
several frequency time series. That will include frequency
time series measured during normal condition (EPFL) as
well as before catastrophic transitions in power grid (India
blackout). Our analysis shows an increase of the fractal
dimension, which could be an indicator of imminent power
system blackout.
II. Evidence of long-range memory in
Switzerland’s power grid
We will provide a description of the voltage magnitude
(V ), frequency (f), and phase angle () times series measured
in the EPFL campus. Then, we apply the DFA
method on these time series to show the existence of longrange
memory.
A. Description of the power system measurements
We use time series of voltage magnitude (V ), frequency
(f), and phase angle () that were collected on the EPFL
campus. There are several PMUs installed at different
locations in EPFL campus to measure all the power
Design and Implementation of Low Ripple Low Power Digital Phase-Locked LoopCSCJournals
We propose a phase-locked loop (PLL) architecture, which reduces the double frequency ripple without increasing the order of loop filter. Proposed architecture uses quadrature numerically–controlled oscillator (NCO) to provide two output signals with phase difference of π/2. One of them is subtracted from the input signal before multiplying with the other output of NCO. The system also provides stability in case the input signal has noise in amplitude or phase. The proposed structure is implemented using field programmable gate array (FPGA), which dissipates 15.44mw and works at clock frequency of 155.8 MHz.
A model of electron pairing, with depletion of mediating phonons at fermi sur...Qiang LI
We present a model of electron pairing based on nonstationary interpretation of electron-lattice interaction. Electron-lattice system has an intrinsic time dependent characteristic as featured by Golden Rule, by which electrons on matched pairing states are tuned to lattice wave modes, with pairing competition happening among multiple pairings associated with one electron state. The threshold phonon of an electron pair having a good quality factor can become redundant and be released from the pair to produce a binding energy. Lattice modes falling in a common linewidth compete with one another, like modes competing in a lasing system. In cuprates, due to near-parallel band splitting at and near Fermi Surface (EF), a great number of electron pairs are tuned to a relatively small number of lattice wave modes, leading to strong mode competition, transfer of real pairing-mediating phonons from EF towards the “kink”, and depletion of these phonons at and near EF.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
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