This document discusses 3D printing and its applications in medicine. It begins by explaining the need for alternative organ therapies due to shortages in donor organs. It then provides an overview of 3D printing, describing the various processes and materials used. Applications discussed include tissue and organ fabrication, customized implants and prosthetics, anatomical models for surgical preparation, and customized drug dosage forms. The document concludes by discussing the cost efficiency and future trends of 3D printing in medicine, including the potential for bioprinting complex human organs.
it is a seminar slide that i prepared on the topic 3d bioprinting. it may be a help to whom taking seminar on that topic. It is not covered its full area only the basics of bio printing ..
Applications of 3 d printing in biomedical engineeringDebanjan Parbat
This presentation deals with the recent and futuristic trends in the field of 3D Printing technology and its applications in the field of bio engineering and medical applications. The 3D printing technology can change the perception of the whole manufacturing industry to health care applications.
Printing of biological organs and tissues.First the concept of 3d printing is known (not in depth),then bioprinting concept is seen.With the help of images the description can be given.
It has been expleined in these slides that how 3D bioprinters work and some of them have been introdused. Also some examples of use 3D bioprinter in reality are introduced.
Finally feature of 3D bioprinters in human life has been explained.
Future of 3D Printing in Pharmaceutical & Healthcare SectorPrashant Pandey
3D Printing is a process of making a physical object from a three dimensional digital model typically by layering down many thin layers of a material in succession
The 3D printing process builds a three-dimensional object from a computer-aided design model, usually by successively adding material layer by layer, which is why it is also called additive manufacturing
it is a seminar slide that i prepared on the topic 3d bioprinting. it may be a help to whom taking seminar on that topic. It is not covered its full area only the basics of bio printing ..
Applications of 3 d printing in biomedical engineeringDebanjan Parbat
This presentation deals with the recent and futuristic trends in the field of 3D Printing technology and its applications in the field of bio engineering and medical applications. The 3D printing technology can change the perception of the whole manufacturing industry to health care applications.
Printing of biological organs and tissues.First the concept of 3d printing is known (not in depth),then bioprinting concept is seen.With the help of images the description can be given.
It has been expleined in these slides that how 3D bioprinters work and some of them have been introdused. Also some examples of use 3D bioprinter in reality are introduced.
Finally feature of 3D bioprinters in human life has been explained.
Future of 3D Printing in Pharmaceutical & Healthcare SectorPrashant Pandey
3D Printing is a process of making a physical object from a three dimensional digital model typically by layering down many thin layers of a material in succession
The 3D printing process builds a three-dimensional object from a computer-aided design model, usually by successively adding material layer by layer, which is why it is also called additive manufacturing
3D-Bioprinting coming of age-from cells to organsDaniel Thomas
Over the past decade, annual spending on pharmaceutical development to treat many endocrinological systems has increased exponentially.
Currently, preclinical studies to test the safety and efficiency of new drugs, use laboratory animals and traditional 2D cell culture models. Neither of these methods are completely accurate reflections of how a drug will react in a human patient.
A solution has emerged in the form of 3D-Bioprinting technology, developed for the scalable, accurate and repeatable deposition of biologically active materials. With advances in this biomanufacturing technology, durable biological tissues for use in testing new pharmaceutical products are now being harnessed and refined.
3D Bio-Printing technique is one of the emerging technique.
Here is the Introduction about 3D Bio-Printing.
It is very basic and understandable level of information about 3D Bio-printing.
3D Bio-Printing; Becoming Economically FeasibleJeffrey Funk
These slides use concepts from my (Jeff Funk) course entitled analyzing hi-tech opportunities to analyze the increasing economic feasibility of bio-printing. Due to a lack of available kidney and other organ donors for organ transplants, 3D printing has emerged as an important alternative for many people. Bioprinting is done by using a computer model of an individual’s body to generate a data set for an organ that can be printed with a 3D printer and grown in a bio-reactor. The falling cost of materials and 3D printers is improving their economic feasibility.
3D printing or additive manufacturing (AM) refers to any of the various processes for printing a three-dimensional object.Primarily additive processes are used, in which successive layers of material are laid down under computer control. These objects can be of almost any shape or geometry, and are produced from a 3D model or other electronic data source. A 3D printer is a type of industrial robot.
http://en.wikipedia.org/wiki/3D_printing
Abstract
Introduction To 3D Printing
History
Types of 3D Scanner
Components Of 3D Printer
Material used for 3D Printing
Working
Software Required For 3D Printing
Advantages Of 3D Printing
Limitations Of 3D Printing
Applications
Future Scope
Conclusion
References
3D BIO PRINTING USING TISSUE AND ORGANSsathish sak
3D bio printing is the process of creating cell patterns in a confined space using 3D printing technologies.
3D bio printing is the layer by layer method to deposit materials known as bioinks to create tissue like structure.
Currently, bioprinting can be used to print tissues and organs to help research drug and pills.
Additive manufacturing or 3D printing is a process of making a three-dimensional solid object of virtually any shape from a digital model. 3D printing is achieved using an additive process, where successive layers of material are laid down in different shapes.
3D-Bioprinting coming of age-from cells to organsDaniel Thomas
Over the past decade, annual spending on pharmaceutical development to treat many endocrinological systems has increased exponentially.
Currently, preclinical studies to test the safety and efficiency of new drugs, use laboratory animals and traditional 2D cell culture models. Neither of these methods are completely accurate reflections of how a drug will react in a human patient.
A solution has emerged in the form of 3D-Bioprinting technology, developed for the scalable, accurate and repeatable deposition of biologically active materials. With advances in this biomanufacturing technology, durable biological tissues for use in testing new pharmaceutical products are now being harnessed and refined.
3D Bio-Printing technique is one of the emerging technique.
Here is the Introduction about 3D Bio-Printing.
It is very basic and understandable level of information about 3D Bio-printing.
3D Bio-Printing; Becoming Economically FeasibleJeffrey Funk
These slides use concepts from my (Jeff Funk) course entitled analyzing hi-tech opportunities to analyze the increasing economic feasibility of bio-printing. Due to a lack of available kidney and other organ donors for organ transplants, 3D printing has emerged as an important alternative for many people. Bioprinting is done by using a computer model of an individual’s body to generate a data set for an organ that can be printed with a 3D printer and grown in a bio-reactor. The falling cost of materials and 3D printers is improving their economic feasibility.
3D printing or additive manufacturing (AM) refers to any of the various processes for printing a three-dimensional object.Primarily additive processes are used, in which successive layers of material are laid down under computer control. These objects can be of almost any shape or geometry, and are produced from a 3D model or other electronic data source. A 3D printer is a type of industrial robot.
http://en.wikipedia.org/wiki/3D_printing
Abstract
Introduction To 3D Printing
History
Types of 3D Scanner
Components Of 3D Printer
Material used for 3D Printing
Working
Software Required For 3D Printing
Advantages Of 3D Printing
Limitations Of 3D Printing
Applications
Future Scope
Conclusion
References
3D BIO PRINTING USING TISSUE AND ORGANSsathish sak
3D bio printing is the process of creating cell patterns in a confined space using 3D printing technologies.
3D bio printing is the layer by layer method to deposit materials known as bioinks to create tissue like structure.
Currently, bioprinting can be used to print tissues and organs to help research drug and pills.
Additive manufacturing or 3D printing is a process of making a three-dimensional solid object of virtually any shape from a digital model. 3D printing is achieved using an additive process, where successive layers of material are laid down in different shapes.
Increasing the efficacy of drugs and at the same time reducing the chances of adverse reaction should be the aim of drug development, which can be achieved by using 3D printing to fabricate personalized medications
Drugs with narrow therapeutic index can easily be prepared using 3D printing; and, by knowing the patient’s pharmacogenetic profile and other characteristics like age, race etc., optimal dosage can be given to the patient.
3D printing technology is a valuable and potential tool for the pharmaceutical sector, leading to personalized medicine focused on the patients’ needs. It offers numerous advantages, such as increasing the cost efficiency and the manufacturing speed. 3D printing has revolutionized the way in which manufacturing is done. It improves the design manufacturing and reduces lead time and tooling cost for new products.
3DPrinting Technologies
echnologiesthatbuild3Dobjectsbyaddinglayer-upon-layerofmaterial,whetherthematerialisplastic,metal,concreteoranycompositematerials. There are three types of Printer.
1.Stereo lithography (SLA)
2.Selective laser sintering (SLS)
3.Fused deposition modeling (FDM)
Role of 3D printing & 3D model in Complex Total Hip Replacement Queen Mary Hospital
Role of 3D printing & 3D model in Complex Total Hip Replacement
Dr. Kalaivanan Kanniyan
for queries - drkkbriyan@gmail.com / drkkbriyan@outlook.com
Asian Joint Reconstruction Institute
AJRI
chennai
India
Tamil nadu
complex hip replacement , knee replacment, knee navigation
Contains all information you need for an introduction to 3d printing. Includes:
What is 3d printing?
Why use 3d printing?
When did it begin?
How does it work? + 2 small videos to show the same
Recent developments and future
This slideshow was compiled according to specs provided by my eCommerce professor. We were tasked with picking an area of technology that was of interest. I have always been fascinated by 3D Printing and I feel that it is a technology that will be greatly expanded in the next 10 years.
3D Printing in healthcare system a crisp overviewMehul Rohit
Greeting everyone, This is a Crisp overview of 3D Printing that was presented by me in a seminar. Looking forward to improve the same, Any suggestion, comment, questions are welcome.
Thank You.
Platform for Tissue Engineering and 3D Printing at La Paz University Hospital...DanielCermeno1
The Tissue Engineering and 3D Printing Platform purpose is to promote the development of research and solutions based on tissue engineering and bioprinting and offer different services as computer imaging, virtual planning, computer aided design, and 3D printing technologies to researchers and clinicians in the fields of Reconstructive and Regenerative Medicine.
The presentation contains all the data about 3D printing. How it is done, what are the various ways of 3D printing process along with its Advantage & Disadvantage, type of raw material used, etc....
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
3. • Organ failure due to aging, disease, accidents and birth
defects.Current treatment of organ failure relies mostly on organ
transplants from living or the deceased.
• There is chronic shortage of human organ availability for
transplant, and it is a difficult task of finding a donor who is a
tissue match.
• Hence therapies based on tissue engineering and regenerative
medicine are a potential solution for organ donor shortage .
THE NEED OF 3D PRINTING IN MEDICINE is in …..
4. WHAT IS 3D PRINTING……………
• 3D printing is a manufacturing method in which objects are made
by fusion or depositing materials-such as plastic, metal, ceramics,
powder, liquids or even living cells in layers to produce a 3D-
OBJECT.
• This process is also referred to as Additive Manufacturing
(AM),Rapid prototyping (RP) or Solid Free form technology (SFF).
5. 3D Printing
Process……
• There are about two dozen of printing processes using
varying 3D printer technologies, speed & resolution
with hundred of 3D building materials.
• These technologies can build a 3D object in any
imaginable shape as defined in the Computer aided
design(CAD.)file.
6. • In the basic step,
The 3D printer first follow the instructions in the
CAD. file to build the foundation for the object, moving
the printer head in the X-Y axis ( x-y ) in
horizontal plane.
• The printer then follows the print head in Z-axis to
build the object vertically layer to layer.
Contd…….
9. Slide Title
• Make Effective Presentations
• Using Awesome Backgrounds
• Engage your Audience
• Capture Audience Attention
SELECTIVE LASER SINTERING (SLS)
10. Slide Title
Product A
• Feature 1
• Feature 2
• Feature 3
Product B
• Feature 1
• Feature 2
• Feature 3
Formed
Object
SELECTIVE LASER SINTERING (SLS) PRINTER
11. It is a non contact technique that uses thermal technology to deposit
BIOINK tiny droplets of living cells or biomaterials on to the substrate
according to digital instructions.
The droplet deposition is done using heat to eject the ink drops.
Heating the printhead creates small air bubbles that collpase creating
pressure pulses that eject ink drops in volume of 10 to 150 picoliters.
THERMAL INKJET PRINTING (TIJ)
15. •Acrylonitrile butadiene styrene (ABS)
•Powders of plaster (POP)
•Teflon
•Mixer of polyamide with glass beads
•Metals- Titanium,Aluminium
MATERIAL SELECTION FOR 3D PRINTING
RIGID MATERIALS
16. •Elastomeric resins
•Nylon: Polyamide
•Alumide = Polyamide + Aluminium
•Strong plastic like legos
USED TO MAKE
- Cartilaginous tissues for dissection purposes.
- Tumours in the context of surgical simulation,
- Arteries to practice transcatheter valve
replacements.
- Soft dummy models can be used to learn biopsy
procedures in Radiology
FLEXIBLE MATERIALS
17. Medical applications for 3D Printing are expanding rapidly and are
expected to revolutionize the health care. Medical uses of 3D Printing,
can be organized into 4 broad categories:
1.Tissue and Organ Fabrication
2.Creation of customized prosthetics.
3.Implants & anatomical models.
4.Pharmaceutical research regarding drug dose forms,
delivery and discovery.
MEDICAL APPLICATIONS OF 3D-PRINTING
18. •3D Bioprinting offers important advantages over the traditional
regenerative methods by:
- Highly precise cell placement
- Precise Cell concentration
•Organs printing takes advantage of 3D printing cell laden biomaterials
,layer by layer ,creating 3D tissue like structures.
•Various materials are available to build scaffolds,depending upon the
strength, porosity and type of tissue with HYDROGELS most suitable for
producing soft tissues.
1. TISSUE & ORGAN FABRICATION
19. 3D PRINTED CARDIAC VALVE
Made from alginate,smooth muscle cells and valve
interstitial cells to control valve stiffness.
3D PRINTED HEART
20. •Implants & prosthesis can be made into any imaginable geometry
through the translation of X ray,CT or MRI Scan (DICOM file) into
digital.stl 3D print file.
•In this way the 3D printing had been successfully used in health care
sector to construct standard & customised prosthetic limbs and surgical
implants,within 24hours.
This approach has been used to fabricate dental,spinal & hip implants.
2.CUSTOMISED IMPLANTS & PROSTHESIS
28. The complexities of human organs make 3D-printing ideal for surgical
preparations.
The CT & MRI reconstructions along with 3D printed neuroanatomical
models are helpful to the neurosurgeons by providing the representation
of most complicated structures in the human body.
3.ANATOMICAL MODELS FOR SURGICAL PREPARATION
30. - Complex drug manufacturing process could be standardised through
the use of 3D Printer.
-3D printers had already been producing novel dosage forms like
microcapsules, multilayered drug delivery devices and
nanosuspensions for precise drug delivery.
-If necessary, the dose may further be adjusted as per clinical response
and age of the patient.
4.CUSTOM 3D-PRINTED DOSAGE FORM & DRUG DELIEVERY DEVICES
31. COST EFFICIENCY
•Ability to produce items cheaply.
•Reducing manufacturing costs by decreasing use of
uneccesary resources.
•A pharmaceutical tablet of 10mg could to custom
fabricated on demand as a 1mg tablet.
32. FUTURE TRENDS
•Bioprinting the complex Human Organs
•In situ, imprinting the living organs in Human body.
•In situ,bioprinting external organs like skin,already taken place.
•Hand held 3D printers in situ for direct repair.
33. 1.SAFETY & SECURITY: 3D printing has given rise to safety & security concerns
because of its unlimited utilisations.It has already been
employed for criminal purposes like making Gun & Gun
magazines, master key formation and even ATM
Skimmers.
2.PATENTS & COPYRIGHT
ISSUES: 3D printing has been of concern in patents,industrial
design,Copyright and trademark laws.
CONTROVERSIES
38. •The 3D printing is a useful and potentially transformative tool in a number of
fields, including Medicine.
•The medical advances using 3D Printing technology are significant and
exciting, especially with advancement in the field of radiology using
dicom.images and 3D recon transferring into 3D printer CAD.files/.stl files.
CONCLUSION
39. 3D EAR TRANSPLANT IN A CASE OF MICROTIA
3D PRINTED HUMAN EAR
3D HUMAN EAR CONSTRUCTION
