The Tissue Engineering and 3D Printing Platform purpose is to promote the development of research and solutions based on tissue engineering and bioprinting and offer different services as computer imaging, virtual planning, computer aided design, and 3D printing technologies to researchers and clinicians in the fields of Reconstructive and Regenerative Medicine.

1. Tissue Engineering &
3D Printing Platform
Daniel Cermeno. Laboratory Manager
Contact: piti3D@idipaz.es
Phone: +34 625 30 13 12

2. Contents

3. Motivation

4. The Tissue Engineering and 3D Printing Platform
purpose is to promote the development of
research and solutions based on tissue
engineering and bioprinting
Offers services of Design, Computer
Imaging, Virtual Planning, and 3D Printing
Main areas of activity:
• Tissue and Organ Bioprinting.
• Lab-on-a-chip (LOC) and Organ-on-a-chip
devices (OOC).
• Tissue engineering-based organ and tissue
modeling.
• Development of Medical Devices (Biomodels,
Surgical guides, Prothesis and Implants) by 3D
printing.
• Virtual computer imaging-aided technical
assistance for surgery planning.
Objectives

5. Contents

6. 3D Printing
Traditional
manufacturing is based
on subtraction
techniques
3D Printing is based on the addition of materials layer-by-layer
allowing to produce complex forms with mesh structures
(scaffolds).

7. Main Advantages
• Perfect implant fit
• Possibility to print a mesh structure for better bone attachment
• Fantastic aesthetic and reconstructive results
• Reduced surgery time and faster recovery
• Best way to maintain/restore a patient’s quality of life
• Reduced treatment cost and shorter hospitalization
• Less blood loss
• Reduced time under anesthesia

8. Contents

9. Neurosurgery and Others

10. Neurosurgery and Others

11. Virtual Planning for Neurosurgery
Cranyosinostosis is a condition in which one or more craneal sutures close
prematurely, impeding the normal development of the brain and changing the normal
bone grow pattern. As a result patient that suffer from this condition have large bone
defects.

12. Surgical Guides for Craneosinostosis
Virtual Planning for Neurosurgery

13. Virtual Planning for Neurosurgery

14. CMF Reconstruction and Simulation

15. Biomodels

16. Contents

17. RM
3DPTI
Bioprinting
Biological Implants Transition
Regenerative medicine (RM) is the branch of the medicine that aims at
finding solutions to regenerate damaged tissues.
Tissue engineering (TE) is the use of a combination of cells, engineering
and materials methods, and suitable signaling factors to improve or
replace biological functions.

18. Bioprinting
Cell-laden
hydrogel
Growth
Factors
Scaffold
Print 3D multi component parts with different materials with a
customized external shape and an internal mesh structure that
mimic human living tissues.

19. Bioprinting

20. Contents

21. 3DnoLOC Colon Organoids Project Corneal Regeneration with 3DP
Skin 3D Printing for Epidermolysis Bullosa
On going Projects at the Platform

22. Success Keys in the Platform
• Strong basic science focused on applied projects oriented to
solve real problems of patients and clinicians.
• State-of-the-art technologies (3DP, Bioprinting…).
• Big emphasis on promotion.
• Collaboration between public and private entities.
• Solid Financial Plans
• Cohesive team with members from different institutions and
disciplines (Biologists, and Engineers).

23. Next Steps
Development of projects in the short term:
• Guides for complex reconstructions.
• Biomodels.
• ATM Custom Made.
• Cartilage bioprinting.
• Anatomical implants.
Financial Resources:
• RETOS
• CDTI
• H2020
• Otros

24. We are looking for…
• New problems to solve with our technologies.
• Participation in consortium projects, and financial applications.
• University agreements for master thesis, and senior students.
• Promotional activities, and participation in congresses in the field.
• Development of new technologies and applications.
• Generate Intellectual Property, and Technology Transfer.
• Increase our team with new professionals.

25. Team
Dr. Ramón Cantero
Director
Dra. María Paz de Miguel
Scientific Advisor
José Manuel Baena
Scientific Coordinator
Daniel Cermeño
Lab Manager
Juan José Pérez Blanco
Investigator

26. Thanks for your
attention
Daniel Cermeno