1. The document discusses the standard treatment for locally advanced cervical cancer, which is concurrent chemoradiotherapy with cisplatin. Several randomized trials from the 1990s showed improved survival with this approach compared to radiotherapy alone. 2. Meta-analyses of these trials demonstrated a 6-8% absolute improvement in survival at 5 years with the addition of chemotherapy to radiotherapy. Cisplatin is the recognized cytotoxic drug used most commonly. 3. The study described in the document investigated the use of ifosfamide and cisplatin with concurrent chemoradiotherapy and consolidation chemotherapy as a potentially improved treatment approach for locally advanced cervical cancer.