Benign Lesion

1. NAME : ALI TAHIR BAJWA
CLASS : 3rd YEAR BDS
Roll No: 1804
CONGENITAL GINGIVAL
GRANULAR CELL TUMOR

2. OUTLINE
INTRODUCTION
CLINICAL FEATURES
HISTOPATHOLOGY
TREATMENT
SUMMARY

3. CONGENITAL GINGIVAL GRANULAR CELL TUMOR
A pedunculated growth on the anterior maxilla or mandible of
newborns that is composed of granular cells.
The congenital gingival granular cell tumor is also known as:
1. Congenital epulis of the newborn
2. Congenital granular cell epulis

4. An infant with a pedunculated,
multilobular lesion of the anterior
alveolar ridge.
Tissue of origin is still
controversial.

5. CLINICAL FEATURES
1. Lesions are found only in newborn
2. Lesions mostly occur in anterior maxilla and occasionally
lesions are found in the anterior mandible
3. Occurrence : Females > Males
4. Lesions are pedunculated, originating from crest of
alveolar ridge
5. Texture: Smooth surface
6. Size: several cm in diameter(1-9)
7. Colour: Pink

6. Hematoxylin and Eosin (H and E)
stained section show uniform
pattern of granular cells with
outer surface of atrophic
stratified squamous epithelium
HISTOPATHOLOGY

7. • Large, rounded cells
• Granular cytoplasm
• Rounded nuclei
High-power microscopy show

8. • Lesion is composed of sheets of large cells with a
granular cytoplasm and vascular, noncollagenous
stroma.
• Lesions contain autophagic vacuoles
• Lesions are negative for S-100 protein

9. TREATMENT
• Surgical Excision that includes the base of stalk
• Recurrence is rare

10. SUMMARY
• Newborns
• Composition: Granular cells
• Lesion is multilobular & pedunculated
• F>M
• Colour: Pink
• Smooth surface
• Size: 1-9 cm
• Treatment: Surgically excised
• Reoccurrence: Rare

11. THANK YOU!!!