The document reports a case of ameloblastoma in a 60-year old female patient. She presented with a swelling on her right cheek that had been growing over the past 2 years. Radiological investigations including OPG and CT scans showed a bicortical expanding lesion in the right body and ramus of the mandible. An incisional biopsy was performed and the provisional diagnosis of ameloblastoma was made.

1. A CASE REPORT ON AMELOBLASTOMA

2. INTRODUCTION True neoplasm of odontogenic epithelium Term “ Ameloblastoma” coined by Churchill – 1934. “ Unicentric, nonfunctional, intermittent in growth, anatomically benign, clinically persistent”. 2 nd most common odontogenic neoplasm, & represents 1% of all oral odontogenic epithelial tumors & 11% of all odontogenic tumors.

3. CASE REPORT

4. 60 year old female c/o swelling on right cheek since 2 years.

5. Extra orally; 1 year back

6. Swelling 1 year back Present size

7. Intra oral swelling

8. 1 year back Present oral swelling

9. Provisional diagnosis – AMELOBLASTOMA Differential diagnosis – 1) Odontogenic Keratocyst 2) Central giant cell granuloma 3) CEOT 4) Odontogenic myxoma 5) COC

10. INVESTIGATIONS Radiological – OPG, lateral occlusal mandibular radiograph Complete blood picture, CT, BT Incisional biopsy

11. Present radiograph 1 year back

12. Bicortical expansion

16. Differential diagnosis – 1) central giant cell granuloma 2) odontogenic Keratocyst 3) odontogenic myxoma 4) ossifying fibroma

17. central giant cell granuloma

18. Odontogenic Keratocyst Right body and ramus of the mandible

19. 03/27/10 Odontogenic myxoma

20. DISCUSSION

21. Etiology – Varied origin cell rests of enamel organ Epithelium of odontogenic cysts Disturbances of developing enamel organ Basal cells of surface epithelium of the jaws Heterotopic epithelium in other parts of the body

22. CLINICAL FEATURES Wide age range, but uncommon in children and adults < 20 yrs of age Posterior mandible Asymptomatic, often discovered on routine radiographs As tumor grows, painless enlargement may be noted

23. RADIOLOGICAL FEATURES Unilocular radiolucency, especially early lesions that often progress to multilocular ( soap-bubble, honeycomb ) May be associated with impacted tooth Cortical expansion and thinning Resorption of adjacent tooth roots, displacement of teeth can be seen