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CYSTS OF ODONTOGENIC
ORIGIN-I
I N D I A N D E N T A L A C A D E M Y
LEADER IN
CONTINUING DENTAL
EDUCATION
www.indiandentalacademy.com
learning objectives
 Student should be able to -
 DEFINE CYST
 CLASSIFY CYSTS
 Describe -Clinical features,Pathogenesis, Radiological
features,Histopathological features & Treatment of
DENTIGEROUS Cyst & ERUPTION cyst
 Differentiate between DENTIGEROUS Cyst & ERUPTION
cyst
www.indiandentalacademy.com
Cyst
 Kramer (1974) has defined a cyst as ‘a pathological cavity
having fluid, semifluid or gaseous contents and which is
not created by the accumulation of pus’.
Most cysts, but not all, are lined by epithelium.
Classification
Cysts of jaws
 Odontogenic
 Non-odontogenic
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Classification by Etiology
A. Developmental
 Dentigerous cyst
 Eruption cyst
 Odontogenic keratocyst
 Gingival cyst of newborn
 Gingival cyst of adult
 Lateral periodontal cyst
 Calcifying odontogenic
cyst
 Glandular odontogenic
cyst
B. Inflammatory
 Periapical cyst
 Residual cyst
 Paradental cyst
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Classification by Tissue of origin
Derived from rests of Malassez
 Periapical cyst
 Residual cyst
Derived from reduced enamel epithelium
 Dentigerous cyst
 Eruption cyst
Derived from dental lamina (rests of serre)
 Odontogenic keratocyst
 Gingival cyst of newborn
 Gingival cyst of adult
 Lateral periodontal cyst
 Glandular odontogenic cyst
Unclassified
 Paradental cyst
 Calcifying odontogenic cystwww.indiandentalacademy.com
Classification by Shear
I Cysts of the jaws
A. Epithelial lined cysts
1. Developmental origin
a) Odontogenic
I. Gingival cyst of infant
II. Odontogenic keratocyst
III. Dentigerous cyst
IV. Eruption cyst
V. Gingival cyst of adult
VI. Developmental lateral periodontal cyst
VII. Botryoid odontogenic cyst
VIII.Glandular odontogenic cyst
IX. Calcifying odontogenic cyst
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b) Non- odontogenic
I. Midpalatal raphe cyst of infants
II. Nasopalatine duct cyst
III. Nasolabial cyst
2. Inflammatory origin
I. Radicular ,apical & lateral
II. Residual cyst
III. Paradental cyst & juvenile paradental cyst
IV. Inflammatory collateral cyst
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B. Non-Epithelial lined cysts
1. Solitary bone cyst
2. Aneurysmal bone cyst
II Cysts associated with the maxillary antrum
1. Mucocele
2. Retention cyst
3. Pseudocyst
4. Postoperative maxillary cyst
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III Cysts of the soft tissues of the mouth, face and neck
1. Dermoid & epidermoid cysts
2. Lymphoepithelial (branchial) cyst
3. Thyroglossal duct cyst
4. Anterior median lingual cyst(intralingual cyst of foregut
origin)
5. Oral cysts with gastric or intestinal epithelium ( oral
alimentary tract cyst)
6. Cystic hygroma
7. Nasopharyngeal cyst
8. Thymic cyst
9. Cysts of the salivary glands: mucous extravasation cyst;
mucous retention cyst;ranula;polycystic (dysgenetic)
disease of the parotid
10. Parasitic cysts: hydatid cyst; Cysticercus
cellulosae;trichinosiswww.indiandentalacademy.com
Dentigerous cyst
(Follicular cyst)
Dentigerous=Tooth bearing
 Definition: An odontogenic
cyst that surrounds the
crown of an impacted tooth;
caused by fluid accumulation
between the REE & the
enamel surface ,resulting in a
cyst in which the crown is
located within the lumen
www.indiandentalacademy.com
Pathogenesis
 Originates after the crown of the tooth has been completely
formed by accumulation of fluid between the REE & the
tooth crown
 May originate initially by proliferation & cystic
transformation of islands of epithelium in the connective
tissue wall of the dental follicle or even outside the follicle &
this transformed epithelium then unites with the lining
follicular epithelium forming a solitary cystic cavity around
the tooth crown
www.indiandentalacademy.com
 Most common among developmental odontogenic cysts
 Associated with
 Crown of impacted, embedded, or unerupted permanent
tooth
 Complex compound odontoma
 Supernumerary tooth
 Seldom deciduous tooth
 May have inflammatory
pathogenesis
Periapical infection of overlying
primary tooth
Pericoronitis around partially
erupted third molars
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Clinical features
 Site
Maxillary & Mandibular third molar
Maxillary canine
Mandibular II PM
 Age
2nd & 3rd decade
 Gender
M>F-3:2
 Mostly solitary
 Syndromic- bilateral & multiple (Cleidocranial dysplasia
& Maroteaux-Lamy syndrome )
www.indiandentalacademy.com
Clinical features
 Expansion of the bone with facial asymmetry
 Hollowing out of ramus
 Displacement of teeth – mandibular third molar towards
inferior alveolar canal, maxi. Canine towards maxilla
 Resorption of adjacent teeth
 Pain or discomfort if secondarily infected
www.indiandentalacademy.com
Radiographic features
 Unilocular radiolucent
area associated with
crown of unerupted tooth
 Well defined & sclerotic
border
www.indiandentalacademy.com
Three radiological varients
a) Central
b) Lateral
c) Circumferential
Central
Lateral
Circumferential
www.indiandentalacademy.com
Distinction between a small
dentigerous cyst & enlarged
follicle ?
3-4 mm –follicular space
More than 5 mm - dentigerous
cyst
www.indiandentalacademy.com
Histopathological features
 A thin layer of stratified
Squamous epithelium
lining the lumen ( as
derived from REE)
 Thin connective tissue wall
composed of loose fibrous
connective tissue
 Retepeg formation is
generally absent ( flat
epithelium –C.T. interface)
 Cystic space
 Reduced enamel
epithelium lining
www.indiandentalacademy.com
 Rushton bodies – linear,
often curved hyaline
bodies
 Presence of islands of
odontogenic epithelium
Ruston bodies
www.indiandentalacademy.com
 Inflammed dentigerous cyst
–thicker epithelial lining
with hyperplastic rete ridges
 Focal areas of mucous cells
Focal areas of mucous cells
thicker epithelial lining
Collagen stroma
www.indiandentalacademy.com
Treatment
 Smaller - surgically removed
 Larger – surgical drain or marsupialization
 Potential complications
1. Development of Ameloblastoma
2. Development of Epidermoid carcinoma
3. Development of Intraosseous mucoepidermoid
carcinoma
www.indiandentalacademy.com
Eruption cyst/ Eruption
Hematoma
Dentigerous cyst occurring in soft
tissue
An odontogenic cyst with
histologic features of a
Dentigerous cyst that surrounds a
tooth crown that has erupted
through bone but not soft tissue
& is clinically visible as a soft
fluctuant mass on the alveolar
ridges
www.indiandentalacademy.com
Clinical features
 Children of different age
group
 Adults-delayed eruption
 Circumscribed,translucent,
fluctuant swelling overlying
the crown of erupting
deciduous or permanent
tooth
 Purple or deep blue =
Eruption hematoma
 Usually painless
www.indiandentalacademy.com
Histological features
 Superficial aspect covered
by keratinized stratified
squamous epithelium of
overlying gingiva
 Dense C.T. strip separates
from cyst
 Cystic cavity is lined by 2-3
cell layers of
nonkeratinized stratified
squamous epithelium
(REE)keratinized stratified squamous
epithelium
www.indiandentalacademy.com
 Connective tissue –
densely cellular, less
collagenous & basophilic
hue due to presence of
higher content of acid
mucopolysaccharides in
ground substance
 If inflamed, presence of
inflammatory infiltrate
 No treatment, as cyst
ruptures spontaneously
densely cellular
www.indiandentalacademy.com
SUMMARY
 1.DEFINITITION & CLASSIFICATION OF CYSTS
 2Clinical features,Pathogenesis, Radiological
features,Histopathological features & Treatment of
DENTIGEROUS Cyst & ERUPTION cyst
www.indiandentalacademy.com
BIBLIOGRAPHY
 Text book of oral pathology Shafer's, 5 & 6th edition
 Cysts of the Oral Regions Shear M 3rd edition
 Color Atlas of Oral Diseases Cawson, R. 2nd edition
 Oral and Maxillofacial Pathology Neville, Brad W. 2nd
 Lucas’s Pathology Of Tumor’s of the Oral Tissues
 Cawson, R. A., Bennie, W. H 5th edition
www.indiandentalacademy.com
THANK U
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Odontogenic cysts i / dental implant courses by Indian dental academy 

  • 1. CYSTS OF ODONTOGENIC ORIGIN-I I N D I A N D E N T A L A C A D E M Y LEADER IN CONTINUING DENTAL EDUCATION www.indiandentalacademy.com
  • 2. learning objectives  Student should be able to -  DEFINE CYST  CLASSIFY CYSTS  Describe -Clinical features,Pathogenesis, Radiological features,Histopathological features & Treatment of DENTIGEROUS Cyst & ERUPTION cyst  Differentiate between DENTIGEROUS Cyst & ERUPTION cyst www.indiandentalacademy.com
  • 3. Cyst  Kramer (1974) has defined a cyst as ‘a pathological cavity having fluid, semifluid or gaseous contents and which is not created by the accumulation of pus’. Most cysts, but not all, are lined by epithelium. Classification Cysts of jaws  Odontogenic  Non-odontogenic www.indiandentalacademy.com
  • 4. Classification by Etiology A. Developmental  Dentigerous cyst  Eruption cyst  Odontogenic keratocyst  Gingival cyst of newborn  Gingival cyst of adult  Lateral periodontal cyst  Calcifying odontogenic cyst  Glandular odontogenic cyst B. Inflammatory  Periapical cyst  Residual cyst  Paradental cyst www.indiandentalacademy.com
  • 5. Classification by Tissue of origin Derived from rests of Malassez  Periapical cyst  Residual cyst Derived from reduced enamel epithelium  Dentigerous cyst  Eruption cyst Derived from dental lamina (rests of serre)  Odontogenic keratocyst  Gingival cyst of newborn  Gingival cyst of adult  Lateral periodontal cyst  Glandular odontogenic cyst Unclassified  Paradental cyst  Calcifying odontogenic cystwww.indiandentalacademy.com
  • 6. Classification by Shear I Cysts of the jaws A. Epithelial lined cysts 1. Developmental origin a) Odontogenic I. Gingival cyst of infant II. Odontogenic keratocyst III. Dentigerous cyst IV. Eruption cyst V. Gingival cyst of adult VI. Developmental lateral periodontal cyst VII. Botryoid odontogenic cyst VIII.Glandular odontogenic cyst IX. Calcifying odontogenic cyst www.indiandentalacademy.com
  • 7. b) Non- odontogenic I. Midpalatal raphe cyst of infants II. Nasopalatine duct cyst III. Nasolabial cyst 2. Inflammatory origin I. Radicular ,apical & lateral II. Residual cyst III. Paradental cyst & juvenile paradental cyst IV. Inflammatory collateral cyst www.indiandentalacademy.com
  • 8. B. Non-Epithelial lined cysts 1. Solitary bone cyst 2. Aneurysmal bone cyst II Cysts associated with the maxillary antrum 1. Mucocele 2. Retention cyst 3. Pseudocyst 4. Postoperative maxillary cyst www.indiandentalacademy.com
  • 9. III Cysts of the soft tissues of the mouth, face and neck 1. Dermoid & epidermoid cysts 2. Lymphoepithelial (branchial) cyst 3. Thyroglossal duct cyst 4. Anterior median lingual cyst(intralingual cyst of foregut origin) 5. Oral cysts with gastric or intestinal epithelium ( oral alimentary tract cyst) 6. Cystic hygroma 7. Nasopharyngeal cyst 8. Thymic cyst 9. Cysts of the salivary glands: mucous extravasation cyst; mucous retention cyst;ranula;polycystic (dysgenetic) disease of the parotid 10. Parasitic cysts: hydatid cyst; Cysticercus cellulosae;trichinosiswww.indiandentalacademy.com
  • 10. Dentigerous cyst (Follicular cyst) Dentigerous=Tooth bearing  Definition: An odontogenic cyst that surrounds the crown of an impacted tooth; caused by fluid accumulation between the REE & the enamel surface ,resulting in a cyst in which the crown is located within the lumen www.indiandentalacademy.com
  • 11. Pathogenesis  Originates after the crown of the tooth has been completely formed by accumulation of fluid between the REE & the tooth crown  May originate initially by proliferation & cystic transformation of islands of epithelium in the connective tissue wall of the dental follicle or even outside the follicle & this transformed epithelium then unites with the lining follicular epithelium forming a solitary cystic cavity around the tooth crown www.indiandentalacademy.com
  • 12.  Most common among developmental odontogenic cysts  Associated with  Crown of impacted, embedded, or unerupted permanent tooth  Complex compound odontoma  Supernumerary tooth  Seldom deciduous tooth  May have inflammatory pathogenesis Periapical infection of overlying primary tooth Pericoronitis around partially erupted third molars www.indiandentalacademy.com
  • 13. Clinical features  Site Maxillary & Mandibular third molar Maxillary canine Mandibular II PM  Age 2nd & 3rd decade  Gender M>F-3:2  Mostly solitary  Syndromic- bilateral & multiple (Cleidocranial dysplasia & Maroteaux-Lamy syndrome ) www.indiandentalacademy.com
  • 14. Clinical features  Expansion of the bone with facial asymmetry  Hollowing out of ramus  Displacement of teeth – mandibular third molar towards inferior alveolar canal, maxi. Canine towards maxilla  Resorption of adjacent teeth  Pain or discomfort if secondarily infected www.indiandentalacademy.com
  • 15. Radiographic features  Unilocular radiolucent area associated with crown of unerupted tooth  Well defined & sclerotic border www.indiandentalacademy.com
  • 16. Three radiological varients a) Central b) Lateral c) Circumferential Central Lateral Circumferential www.indiandentalacademy.com
  • 17. Distinction between a small dentigerous cyst & enlarged follicle ? 3-4 mm –follicular space More than 5 mm - dentigerous cyst www.indiandentalacademy.com
  • 18. Histopathological features  A thin layer of stratified Squamous epithelium lining the lumen ( as derived from REE)  Thin connective tissue wall composed of loose fibrous connective tissue  Retepeg formation is generally absent ( flat epithelium –C.T. interface)  Cystic space  Reduced enamel epithelium lining www.indiandentalacademy.com
  • 19.  Rushton bodies – linear, often curved hyaline bodies  Presence of islands of odontogenic epithelium Ruston bodies www.indiandentalacademy.com
  • 20.  Inflammed dentigerous cyst –thicker epithelial lining with hyperplastic rete ridges  Focal areas of mucous cells Focal areas of mucous cells thicker epithelial lining Collagen stroma www.indiandentalacademy.com
  • 21. Treatment  Smaller - surgically removed  Larger – surgical drain or marsupialization  Potential complications 1. Development of Ameloblastoma 2. Development of Epidermoid carcinoma 3. Development of Intraosseous mucoepidermoid carcinoma www.indiandentalacademy.com
  • 22. Eruption cyst/ Eruption Hematoma Dentigerous cyst occurring in soft tissue An odontogenic cyst with histologic features of a Dentigerous cyst that surrounds a tooth crown that has erupted through bone but not soft tissue & is clinically visible as a soft fluctuant mass on the alveolar ridges www.indiandentalacademy.com
  • 23. Clinical features  Children of different age group  Adults-delayed eruption  Circumscribed,translucent, fluctuant swelling overlying the crown of erupting deciduous or permanent tooth  Purple or deep blue = Eruption hematoma  Usually painless www.indiandentalacademy.com
  • 24. Histological features  Superficial aspect covered by keratinized stratified squamous epithelium of overlying gingiva  Dense C.T. strip separates from cyst  Cystic cavity is lined by 2-3 cell layers of nonkeratinized stratified squamous epithelium (REE)keratinized stratified squamous epithelium www.indiandentalacademy.com
  • 25.  Connective tissue – densely cellular, less collagenous & basophilic hue due to presence of higher content of acid mucopolysaccharides in ground substance  If inflamed, presence of inflammatory infiltrate  No treatment, as cyst ruptures spontaneously densely cellular www.indiandentalacademy.com
  • 26. SUMMARY  1.DEFINITITION & CLASSIFICATION OF CYSTS  2Clinical features,Pathogenesis, Radiological features,Histopathological features & Treatment of DENTIGEROUS Cyst & ERUPTION cyst www.indiandentalacademy.com
  • 27. BIBLIOGRAPHY  Text book of oral pathology Shafer's, 5 & 6th edition  Cysts of the Oral Regions Shear M 3rd edition  Color Atlas of Oral Diseases Cawson, R. 2nd edition  Oral and Maxillofacial Pathology Neville, Brad W. 2nd  Lucas’s Pathology Of Tumor’s of the Oral Tissues  Cawson, R. A., Bennie, W. H 5th edition www.indiandentalacademy.com

Editor's Notes

  1. Dentigerous cyst preferable Not follicular cyst -1. dental follicle –mesodermal origin.2. more commonly used to refer ovary cyst & hair follicle cyst