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Cancer Immunotherapy
Types of cancer
immunotherapy
Immune checkpoint inhibitors1
Monoclonal antibodies2
Cancer vaccines
Nonspecific immune stimulation
3
4
Immune checkpoint inhibitors
These drugs basically take the ‘brakes’ off
the immune system, which helps it
recognize and attack cancer cells.
PD-1
IDO CTLA4
PD-L1
Hot Targets
TDO
PD-1 inhibitors:
Nivolumab
Pidilizumab
Pembrolizumab
MEDI0680
AMP-224
PD-L1 inhibitors:
Avelumab
Durvalumab
BMS-936559
MPDL3280A
MSB-0010718C
IDO inhibitors:
NLG-919
Febuxostat
Annulin B
Halicloic acid A
Benzomalvin C
CTLA4 inhibitors
Ipilimumab
Tremelimumab
MK-0668
TDO inhibitors
LM 10
680C91
RG7-0099
Monoclonal antibodies
These are man-made versions of immune
system proteins. Antibodies can be very
useful in treating cancer because they can
be designed to attack a very specific part of
a cancer cell.
Naked monoclonal
antibodies
Conjugated monoclonal
antibodies
Bispecific monoclonal
antibodies
Cancer vaccines
Vaccines are substances put into the body
to start an immune response against certain
diseases. We usually think of them as being
given to healthy people to help prevent
infections. But some vaccines can help
prevent or treat cancer.
Nonspecific immune
stimulation
These treatments boost the immune
system in a general way, but this can still
help the immune system attack cancer cells.
TLR
STING COX-2
CXCR
Hot Targets
Cytokine Receptor
TLR inhibitors:
Hydroxychloroquine sulfate
Atractylenolide I
SM 324405
Chloroquine diphosphate
Resiquimod
CXCR inhibitors:
SB 332235
AMD-070
CTCE 9908
TC 14012
STING inhibitors:
DMXAA
c-di-UMP
c-di-IMP
COX-2 inhibitors
Acemetacin
Zaltoprofen
Xanthohumol
Cytokine Receptor inhibitors
AF 12198
YM 90709
CC-1088
Contact us
Email: info@bocsci.com
Address: 45-16 Ramsey Road, Shirley,
NY 11967, USA

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Cancer immunotherapy boc sciences

  • 2. Types of cancer immunotherapy Immune checkpoint inhibitors1 Monoclonal antibodies2 Cancer vaccines Nonspecific immune stimulation 3 4
  • 3. Immune checkpoint inhibitors These drugs basically take the ‘brakes’ off the immune system, which helps it recognize and attack cancer cells.
  • 4. PD-1 IDO CTLA4 PD-L1 Hot Targets TDO PD-1 inhibitors: Nivolumab Pidilizumab Pembrolizumab MEDI0680 AMP-224 PD-L1 inhibitors: Avelumab Durvalumab BMS-936559 MPDL3280A MSB-0010718C IDO inhibitors: NLG-919 Febuxostat Annulin B Halicloic acid A Benzomalvin C CTLA4 inhibitors Ipilimumab Tremelimumab MK-0668 TDO inhibitors LM 10 680C91 RG7-0099
  • 5. Monoclonal antibodies These are man-made versions of immune system proteins. Antibodies can be very useful in treating cancer because they can be designed to attack a very specific part of a cancer cell. Naked monoclonal antibodies Conjugated monoclonal antibodies Bispecific monoclonal antibodies
  • 6. Cancer vaccines Vaccines are substances put into the body to start an immune response against certain diseases. We usually think of them as being given to healthy people to help prevent infections. But some vaccines can help prevent or treat cancer.
  • 7. Nonspecific immune stimulation These treatments boost the immune system in a general way, but this can still help the immune system attack cancer cells.
  • 8. TLR STING COX-2 CXCR Hot Targets Cytokine Receptor TLR inhibitors: Hydroxychloroquine sulfate Atractylenolide I SM 324405 Chloroquine diphosphate Resiquimod CXCR inhibitors: SB 332235 AMD-070 CTCE 9908 TC 14012 STING inhibitors: DMXAA c-di-UMP c-di-IMP COX-2 inhibitors Acemetacin Zaltoprofen Xanthohumol Cytokine Receptor inhibitors AF 12198 YM 90709 CC-1088
  • 9. Contact us Email: info@bocsci.com Address: 45-16 Ramsey Road, Shirley, NY 11967, USA

Editor's Notes

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