The document discusses India's Weekly Iron and Folic Acid Supplementation (WIFS) program and National Iron Plus Initiatives (NIPI) which aim to reduce anemia among adolescents and children. The key strategies of the programs include weekly supplementation of IFA tablets through schools and Anganwadi centers, deworming, and nutrition education. Anemia negatively impacts productivity and child development. Proper storage, administration and monitoring of IFA distribution are emphasized to ensure the success of the initiatives.
The slides contain description of weaning foods and artifical feeding given to the baby, important points to be considered while preparing feed for the baby
The slides contain description of weaning foods and artifical feeding given to the baby, important points to be considered while preparing feed for the baby
Supplementary nutritional programmes in indiaDrBabu Meena
This presentation was made to describe the scarcity of food in the country and to teach about the steps taken by the government. This decribes about the various nutritional supplementation progammes in the India, their advantage and disadvantages.
A discourse the ideal feeding practices from pregnancy to infancy with a closer look into malnutrition, breastfeeding, complementary feeding and related interventions.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
2. WIFS(weekly iron & folic acid supplementation
programme)
• Content-
• -Evidence
• -Causes of maternal death and contribution of iron deficiency anemia
• -Health economics of micronutrient deficiencies in children
• -Intergenration cycle of Anemia
• -Strategis for prevention of IDA
3.
4.
5. RATIONAL : EVIDENCE
• Anemia is multi- factoral in etiology
• Iron and folate deficiency are common
• Iron deficiency is related to nutritional deficiency, intestinal
helminthic deficiency and folate deficiency due to poor intake and
chronic hemolytic stage.
• Anaemia in pregnant women reduces woman ability to survive
bleeding during and after child birth.
• Besides these, malaria and other chronic diseases like- Tuberculosis,
HIV and Cancers remain as Major contributors to Anemia.
6.
7. #HEALTH ECONOMICS OF
MICRONUTRIENTS DEFICIENCIES IN CHILDREN
• Anemia and other key micronutrient deficiencies can directly
attribute or to
• Depressed cognition
• Inferior school performance
• Reduced future earnings and productivity
• Depressed immunity
• Repeated infection .
8.
9. HEALTH ECONOMICS OF ANEMIA
• □IMPACT ON PRODUCTIVITY.
• In an anemic individual the aerobic capacity endurance and energy
Efficiency are compromised 10-50%.
• Anemia hits hard on productivity with an estimate of 5% deficit
among all “blue collar” jobs to additional 17% loss for heavy manual
labour such as agriculture and construction.
10. IMPACT ON CHILDREN
• Iron deficiency Anaemia severaly affects cognitive performance.
• It also impacts language skill, motor skills and coordination among
infants and young children and a deficit of 5 to 10 points in
intelligence quotient(IQ).
• Anemic children score 0.5 ti 1.5 SD lower intelligence tests where as
iron interventions have similar magnitude of positive impact on
cognitive scores.
11.
12. THE COST IMPLICATION INCLUDE:
• Increased length of hospital stay.
• Expenses related to hospital, transport of cases to hospitals with
pediatric care facilities.
• Cost of incubatars and intensive care.
• Cost of post maternity care.
• # these all result in burdan on state health budget.
13.
14. STRATEGIES FOR PREVENTION OF IDA
• Dietry diversification.
• Food fortification.
• IFA supplementation with biannual deworming.
• Provide improved health services.
• Dietary diversification.
15.
16.
17.
18. OBJECTIVE:
• The ministry of health and family welfare government of India has
launched the weekly iron and folic acid supplementation (WIFS)
programme to reduce the prevalence and severity of nutritional
Anaemia in adolescent population (10-19 years) and NIPI for age
group 6 month to 10 years.
19. Weekly Iron And Folic Acid
Supplemention(WIFS) Programme:
• Will be planned and implemented for the following two target groups
in both rural and urban areas.
• Adolescent girls and boys enrolled in government/government aided/
Municipal schools from 6th To 12th classes.
20. NATIONAL IRON PLUS INTIATIVES:
• Girls and boys enrolled in government/ government aided/ Municipal
schools from 1th to 5th classes.
• 6 month to 60 month children through AWCS.
21.
22. STRATEGY FOR PREVENTION ANAEMIA
IN ADOLESCENTS:
• Fixed day.
• Institutions based.
• Supervised consumption.
• Educating correct dietary practices and increasing iron intake.
• Screening for moderate/severe anemia and referring.
• Annual/ biannual deworming.
23.
24. EDUCATION SYSTEM APPROACHES:
• Weekly supplemention of IFA Tablet’s on fixed day approach to
school going girls and boys in the age group of 10- 19 yrs.
• Supervised consumption of IFA.
• School based deworming programme.
• Nutrition education to increase consumption of iron rich food.
25. ICDS APPROACHES:
• At AWCs these Tablet’s are distributed free of cost to adolescent girls
Who is Out of school.
• For adolescent girls married/ unmarried weekly IFA for 52 weeks in a
year.
• INFORMATION, COUNSELLING AND SUPPORT TO ADOLESCENT
GIRLS ON:
• How to prevent anemia and
• How to minimise the potential undesirable effects of WIFS.
• Referral services for adolescent girls suffering from moderate and
severe anemia.
26. DISTRICT EDUCATION AND ICDS
DEPARTMENT:
• Ensure monitoring of programme with monthly data collection from
block level.
• Ensure uninterrupted supply of IFA tablets at block level ( School and
AWC).
• Ensure complication of training/Orientation sessions of block
officers, teachers, ICDS , supervisors, ANM, AWW, ASHA and MO-
PHC.
• Ensure IEC material display at school and AWC.
27. BLOCK EDUCATION OFFICER AND
CDPO/ICDS OFFICER:
• Consolidated requirement from schools and ICDS Project for block
supply and share with district level.
• Set- up distribution for schools and AWO
• Ensure uninterrupted supply of IFA.
• Consolidated monitoring data and share with District.
• Conduct quarterly meeting to review the programme.
28. ESTIMATION OF IFA
• # EDUCATION:
• IFA tablet for the year =(52×total number of children in 6 to 12th
standard) + ( 52 tablets/ per teacher/ year.) An additional 20% stock
as buffer will be added.
• ICDS
• Estimating IFA tablet supply = (Number of adolescent girls registered
with ICDS × 52 tablets) + ( 52 tablets/year of each AWW + 52 Tablets/
year for ASHA). An additional 20% is yo be added for ensuring
adequate stock supply.
29.
30. WIFS –IFA DRUGS ( STORAGE)
• STORAGE- WIFS-IFA should be kept in cool and dry place. (AVOID EXPOSURE OF SUNLIGHT AND
WATER).
• SELECTION OF PROPER PLACE:-
• Locke and key room.
• Limited access to the store
• KEEP STORE IN GOOD CONDITION:-
• Control the temperature in the store.
• Control the light in the store
• Prevent water damageand Control humidity
• Keep the store free of pests .
• KEEP YOUR STORE CLEAN AND ORGANISED:-
• Clean the store and keep it tidy.
• Store supplies on shelves.
31. WIFS- IFA DRUGS (ADMINISTRATION)
• ADMINISTRATION:- IFA drugs should be administered weekly, school
– Monday, AWCS – Thursday) to adolescent ( 10-19 years) school
going adolescent and out of school adolescent girls after mid day
meal/ poshahaar (NOT EMPTY STOMACH).
• FEFO( First Expiry First Out).
• Check Expiry in Routin.