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HN Unscheduled and Emergency Care 
Topic: Musculoskeletal 
Topic Number:7
Learning Outcomes 
By the end of this lecture you should be able to 
discuss: 
• the healing process in bone. 
• classifications of fracture. 
• the normal timescales for the stages of healing. 
• factors that affect healing. 
• In-hospital principles of management of fractures.
Fractures
Functions and Composition of Bone 
Tissue components 
• 25% water 
• 25% protein fibres 
(notably collagen) 
• 50% mineral salts 
(Primarily Calcium 
Phosphate) 
• Strong yet lightweight 
Functions 
• Support and Protection 
• Assist movement 
• Mineral "bank" (Ca & Phosphate) 
• Blood cell production - haemopoesis 
(red marrow) 
• Energy storage - adipose tissue 
(yellow marrow)
Fracture healing: Stage 1 
 Blood vessels and 
nerves are ruptured 
 Haematoma formation 
 Macrophages remove 
dead cell tissue
Fracture healing: Stages 2 and 3 
• Chondrocytes and 
fibroblasts form ‘soft 
callus’ 
• Fracture unites – stage 3
Fracture healing: Stage 4 
• Hard callus formation and 
consolidation 
• Callus becomes mineralized 
into woven bone 
• Osteoblasts lay down bone
Fracture healing: Stage 5 
• Remodeling 
• Osteoclasts erode surface to 
allow osteoblasts to lay 
down further bone 
• Callus is reshaped along 
lines of stress
Fracture healing timescales 
Stage Features Time 
Inflammation Site protection & clearance 
Healing process begins 
0 – 2 weeks 
Callus formation Scaffold for new bone 
Soft  hard 
Fluffy opacity on x-ray 
2 – 3 weeks 
Union Bridging by cartilage / immature bone 
Fracture stable but weak 
4 – 6 weeks 
Consolidation All callus replaced by bone 
Immature bone  lamellar bone 
Bone secure 
6 – 8 weeks 
Remodelling Continued osteoblast / osteoclast activity 
Reshaping to best density and shape 
 1 – 2 years
Remodelling
Classification of Fractures: Aetiology 
1. Direct violence 
2. Indirect violence 
Spontaneously e.g following a muscle contraction – avulsion 
3. Pathological 
Abnormally weak bone: tumours, cysts, osteoporosis 
4. Fatigue/stress 
Commonest in 2nd metatarsal in young adults (march #), also tibia in 
runners and vertebrae in fast bowlers
Fracture types
Classification of Fractures: 
Open or closed 
• Also known as compound 
and simple 
• Closed fractures – no 
open wound
Clinical Examination 
• History 
• Pain over # site 
• Loss of function 
• Deformity 
• Crepitus 
• Swelling 
• Radiographically – at least 
two different views 
• Stress films, CT, MRI, bone 
scans
Principles of Management 
1. Reduction 
2. Immobilisation 
3. Rehabilitation
Stabilisation – simple external 
Collar & cuff splint 
Cast/ POP
Stabilisation – external 
pneumatic cast 
Functional brace
Stabilisation - traction
External fixation 
Halo brace 
Ilizarov frame
Internal fixation 
Dynamic hip screw
Immediate Complications Following a 
Fracture 
• Injury to major blood vessels  haemorrhage 
• Damage and injury to surrounding soft tissues i.e. nerves, 
viscera, ligaments, tendons, joints 
• Compartment syndrome
Early Complications 
• Infection-– open fracture 
• Pulmonary embolism – fatal !
Late complications 
 Delayed union (3-4/12)/ Mal union/ non union: 
Smokers, Alcoholics, DM 
 Fear of WB 
• Avascular necrosis – # NOF 
• Shortening – especially in children when epiphyseal plate 
disruption has occurred 
• CRPS (complex regional pain syndrome)– on removal of 
POP 
• Secondary osteoarthritis
Mal-union 
Healing with faulty 
shape 
Non-union 
Healing process stops 
Avascular necrosis 
Ischaemia  
bone death
End of presentation 
© Pearson College 2013

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Week7musculoskeletallecture

  • 1. HN Unscheduled and Emergency Care Topic: Musculoskeletal Topic Number:7
  • 2. Learning Outcomes By the end of this lecture you should be able to discuss: • the healing process in bone. • classifications of fracture. • the normal timescales for the stages of healing. • factors that affect healing. • In-hospital principles of management of fractures.
  • 4. Functions and Composition of Bone Tissue components • 25% water • 25% protein fibres (notably collagen) • 50% mineral salts (Primarily Calcium Phosphate) • Strong yet lightweight Functions • Support and Protection • Assist movement • Mineral "bank" (Ca & Phosphate) • Blood cell production - haemopoesis (red marrow) • Energy storage - adipose tissue (yellow marrow)
  • 5. Fracture healing: Stage 1  Blood vessels and nerves are ruptured  Haematoma formation  Macrophages remove dead cell tissue
  • 6. Fracture healing: Stages 2 and 3 • Chondrocytes and fibroblasts form ‘soft callus’ • Fracture unites – stage 3
  • 7. Fracture healing: Stage 4 • Hard callus formation and consolidation • Callus becomes mineralized into woven bone • Osteoblasts lay down bone
  • 8. Fracture healing: Stage 5 • Remodeling • Osteoclasts erode surface to allow osteoblasts to lay down further bone • Callus is reshaped along lines of stress
  • 9. Fracture healing timescales Stage Features Time Inflammation Site protection & clearance Healing process begins 0 – 2 weeks Callus formation Scaffold for new bone Soft  hard Fluffy opacity on x-ray 2 – 3 weeks Union Bridging by cartilage / immature bone Fracture stable but weak 4 – 6 weeks Consolidation All callus replaced by bone Immature bone  lamellar bone Bone secure 6 – 8 weeks Remodelling Continued osteoblast / osteoclast activity Reshaping to best density and shape  1 – 2 years
  • 11. Classification of Fractures: Aetiology 1. Direct violence 2. Indirect violence Spontaneously e.g following a muscle contraction – avulsion 3. Pathological Abnormally weak bone: tumours, cysts, osteoporosis 4. Fatigue/stress Commonest in 2nd metatarsal in young adults (march #), also tibia in runners and vertebrae in fast bowlers
  • 13. Classification of Fractures: Open or closed • Also known as compound and simple • Closed fractures – no open wound
  • 14. Clinical Examination • History • Pain over # site • Loss of function • Deformity • Crepitus • Swelling • Radiographically – at least two different views • Stress films, CT, MRI, bone scans
  • 15. Principles of Management 1. Reduction 2. Immobilisation 3. Rehabilitation
  • 16. Stabilisation – simple external Collar & cuff splint Cast/ POP
  • 17. Stabilisation – external pneumatic cast Functional brace
  • 19. External fixation Halo brace Ilizarov frame
  • 21. Immediate Complications Following a Fracture • Injury to major blood vessels  haemorrhage • Damage and injury to surrounding soft tissues i.e. nerves, viscera, ligaments, tendons, joints • Compartment syndrome
  • 22. Early Complications • Infection-– open fracture • Pulmonary embolism – fatal !
  • 23. Late complications  Delayed union (3-4/12)/ Mal union/ non union: Smokers, Alcoholics, DM  Fear of WB • Avascular necrosis – # NOF • Shortening – especially in children when epiphyseal plate disruption has occurred • CRPS (complex regional pain syndrome)– on removal of POP • Secondary osteoarthritis
  • 24. Mal-union Healing with faulty shape Non-union Healing process stops Avascular necrosis Ischaemia  bone death
  • 25. End of presentation © Pearson College 2013