General method of the preparation of Bacterial Infections, Toxoids, Viral vaccine, Antitoxins, Serum-immune blood derivatives and other products relative to immunity.
PREPARATION OF BACTERIAL VACCINES:
Steps involved in killed bacterial vaccine preparation:
1. Selection of an antigen:
The exact strain or strains to be incorporated for preparation of bacterial vaccine.
Eg. Cholera vaccine: smooth strains of the two serological types Inaba and Ogawa
TABC vaccine: O and H antigens in S. typhi and S. paratyphi microorganisms and these organisms also contains Vi antigen.
Each strain is carefully checked for freedom from variation and absence of contaminating organisms.
Biotechnology with reference to pharmaceutical scienceAdarsh Patil
Introduction: Hisory
Biotechnology Biology + Technology
Defn:-
Any Technological application that uses biological system, living organisms, cells, tissues, explants or derivatives thereof, to make or modify products or process for specific uses.
Use of microbes in industry. Production of enzymes-General consideration-Amyl...Steffi Thomas
Industrial uses of microbes, properties of useful industrial microbes, various industrial products, production of enzymes-general consideration-amylase, catalase, peroxidase, lipase, protease, penicillinase, procedure for culturing bacteria and inoculum preparation, submerged fermentation and solid state fermentation, uses of different enzymes
UNIT-5 Protein Engineering: Brief introduction to protein engineering,Use of ...Shyam Bass
UNIT-5 6th Sem B.PHARMA PHARMACEUTICAL BIOTECHNOLOGY)
Protein Engineering: Brief introduction to protein engineering, Use of microbes in industry, Production of enzymes-general considerations, Amylase, Catalase, peroxidase, Lipase Basic principles of genetic engineering
BY- SHYAM BASS
PREPARATION OF BACTERIAL VACCINES:
Steps involved in killed bacterial vaccine preparation:
1. Selection of an antigen:
The exact strain or strains to be incorporated for preparation of bacterial vaccine.
Eg. Cholera vaccine: smooth strains of the two serological types Inaba and Ogawa
TABC vaccine: O and H antigens in S. typhi and S. paratyphi microorganisms and these organisms also contains Vi antigen.
Each strain is carefully checked for freedom from variation and absence of contaminating organisms.
Biotechnology with reference to pharmaceutical scienceAdarsh Patil
Introduction: Hisory
Biotechnology Biology + Technology
Defn:-
Any Technological application that uses biological system, living organisms, cells, tissues, explants or derivatives thereof, to make or modify products or process for specific uses.
Use of microbes in industry. Production of enzymes-General consideration-Amyl...Steffi Thomas
Industrial uses of microbes, properties of useful industrial microbes, various industrial products, production of enzymes-general consideration-amylase, catalase, peroxidase, lipase, protease, penicillinase, procedure for culturing bacteria and inoculum preparation, submerged fermentation and solid state fermentation, uses of different enzymes
UNIT-5 Protein Engineering: Brief introduction to protein engineering,Use of ...Shyam Bass
UNIT-5 6th Sem B.PHARMA PHARMACEUTICAL BIOTECHNOLOGY)
Protein Engineering: Brief introduction to protein engineering, Use of microbes in industry, Production of enzymes-general considerations, Amylase, Catalase, peroxidase, Lipase Basic principles of genetic engineering
BY- SHYAM BASS
UNIT 4 Microbial genetics:Transformation,Transduction,Conjugation,Plasmids an...Shyam Bass
(6th Sem B.Pharma Pharmaceutical Biotechnology)
Microbial genetics:
• Transformation,
• Transduction,
• Conjugation,
• Plasmids and transposons,
• Study of the production of - Penicillins, Citric acid, Vitamin B12, Glutamic acid,
Griseofulvin,
• Blood Products: Collection, Processing, and Storage of whole human blood,Dried
human plasma, Plasma substitutes
BY- SHYAM BASS
UNIT-1 Introduction to biotechnology and enzyme immobilisation Brief introduc...Shyam Bass
(6th Sem B.Pharma Pharmaceutical Biotechnology)
UNIT-1 Introduction to biotechnology and enzyme immobilization Brief introduction to biotechnology, Enzyme biotechnology- methods of enzyme immobilization and applications, biosensors- working and applications of biosensors in pharmaceutical industries
Regulations in India (ASU DTAB, ASU DCC), Regulation of
manufacture of ASU drugs - Schedule Z of Drugs & Cosmetics Act for ASU drugs.
Introduction
Regulatory Requirements
Key function of regulatory agencies
Regulation in India
DRUG TECHNICAL ADVISORY BOARD
Drugs Consultative committee-DCC
Schedule Z of Drugs & Cosmetics Act for ASU drugs.
Herbs, Herbal Drugs
Present Scope of Herbal Drug Industry
Scope of Herbal Drug Medicine and Industry
Indian Herbal Industry
International Scope of Herbal Medicines
World Wide Herbal Trade
Overview on plant based industries and research institutions in India
List of few herbal drug industries in India
List of few herbal research institution/ centres in India
General Introduction to Herbal Industry
Herbal drugs industry: Present scope and future prospects.
A brief account of plant based industries and institutions involved in work on medicinal and
aromatic plants in India.
UNIT 6 Fermentation technology, Fermenters, Study of Media, types of fermenta...Shyam Bass
UNIT-6 6th Sem B.Pharma Pharmaceutical Biotechnology-
Following slides include-
Fermentation technology and biotechnological products :
Fermentation methods and general requirements
Study of media
Equipment
Sterilization methods
Aeration process
Stirring
large scale production fermenter design and its various controls
BY- SHYAM BASS
UNIT 4 Microbial genetics:Transformation,Transduction,Conjugation,Plasmids an...Shyam Bass
(6th Sem B.Pharma Pharmaceutical Biotechnology)
Microbial genetics:
• Transformation,
• Transduction,
• Conjugation,
• Plasmids and transposons,
• Study of the production of - Penicillins, Citric acid, Vitamin B12, Glutamic acid,
Griseofulvin,
• Blood Products: Collection, Processing, and Storage of whole human blood,Dried
human plasma, Plasma substitutes
BY- SHYAM BASS
UNIT-1 Introduction to biotechnology and enzyme immobilisation Brief introduc...Shyam Bass
(6th Sem B.Pharma Pharmaceutical Biotechnology)
UNIT-1 Introduction to biotechnology and enzyme immobilization Brief introduction to biotechnology, Enzyme biotechnology- methods of enzyme immobilization and applications, biosensors- working and applications of biosensors in pharmaceutical industries
Regulations in India (ASU DTAB, ASU DCC), Regulation of
manufacture of ASU drugs - Schedule Z of Drugs & Cosmetics Act for ASU drugs.
Introduction
Regulatory Requirements
Key function of regulatory agencies
Regulation in India
DRUG TECHNICAL ADVISORY BOARD
Drugs Consultative committee-DCC
Schedule Z of Drugs & Cosmetics Act for ASU drugs.
Herbs, Herbal Drugs
Present Scope of Herbal Drug Industry
Scope of Herbal Drug Medicine and Industry
Indian Herbal Industry
International Scope of Herbal Medicines
World Wide Herbal Trade
Overview on plant based industries and research institutions in India
List of few herbal drug industries in India
List of few herbal research institution/ centres in India
General Introduction to Herbal Industry
Herbal drugs industry: Present scope and future prospects.
A brief account of plant based industries and institutions involved in work on medicinal and
aromatic plants in India.
UNIT 6 Fermentation technology, Fermenters, Study of Media, types of fermenta...Shyam Bass
UNIT-6 6th Sem B.Pharma Pharmaceutical Biotechnology-
Following slides include-
Fermentation technology and biotechnological products :
Fermentation methods and general requirements
Study of media
Equipment
Sterilization methods
Aeration process
Stirring
large scale production fermenter design and its various controls
BY- SHYAM BASS
Effects of Biocides on antibiotic resistanceGreenFacts
Biocides are added to many consumer goods such as cosmetics and detergents to kill bacteria or inhibit their growth. They include disinfectants, preservatives as well as antiseptics and are widely used in animal husbandry, food production and health care.
There is concern that this widespread use of biocides may lead to the emergence or proliferation of harmful bacteria that are resistant to both biocides and antibiotics.
In the light of current scientific evidence, can biocides lead to antibiotic resistant bacteria?
BioVie Inc. (NASDAQ: BIVI) is a clinical-stage company developing innovative drug therapies for liver disease. The Company’s drug candidate, BIV201 (continuous infusion terlipressin), has an Orphan Drug designation for the treatment of refractory ascites, FDA Fast Track status, and US patent pending. BIV201 also has an Orphan Drug designation for the treatment of hepatorenal syndrome (HRS). The active agent in BIV201, terlipressin, is approved for use in about 40 countries for the treatment of related complications of advanced liver cirrhosis but is not available in the US or Japan. The FDA has never approved terlipressin. BioVie is targeting this landmark achievement.
Institution's Innovation Council (IIC) of Noida Institute of Engineering and Technology (Pharmacy Institute) organized a webinar on "Career Talk: How to ace summer internship?" keynote lecture was delivered by Abhijit Debnath, Asst. Professor NIET (Pharmacy Institute).
Hands-On Training on “Screening of Natural Compounds by Molecular Docking, A...Theabhi.in
Invited Lecture on “Screening of Natural Compounds by Molecular Docking, ADME, Toxicity Studies: Hands-On Training,” Organized by BACS, University of Delhi
Drosophila Model for toxicity Assessment of Nanoparticle based Drug Developme...Theabhi.in
Short Term Training Course on DROSOPHILA BIOLOGY AND NANOBIOTECHNOLOGY (STTC Programme for Mid Career Scientist/UG & PG Teaching Faculty) | 6-20 April 2021
Introduction to various Instructional tools for HEIs by Abhijit DebnathTheabhi.in
Invited talk on One Week Online Faculty Development Programme on "Enhancing Pedagogy through Innovative Instructional Tools for HEIs" 18-24th December 2023
Organized by Faculty of Humanities & Social Sciences, Assam down town University
Video Lecture is available at https://www.youtube.com/watch?v=DXu_CLgB4q0
Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates. Approaches to design-controlled release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and
biological properties of drugs relevant to controlled release formulations.
Introduction to Novel Drug Delivery SystemsTheabhi.in
Full lecture is available in youtube
Part1: https://youtu.be/-8v5VmM-kVg
Part2: https://youtu.be/TdrEUEDAcbU
The Lecture includes:
Introduction to Novel Drug Delivery Systems
What is Drug?
Drug Discovery and Drug Development
Challenges in Drug Discovery & Drug Development
Novel Drug Delivery Systems
Conventional vs Novel Drug Delivery Systems
Various Novel Drug Delivery Systems
NDDS Course contents are available at https://theabhi.in/pharma/ndds
Unit 4 - Informatics & Methods in drug design: Introduction to Bioinformatics, chemoinformatics. ADME databases, chemical, biochemical and pharmaceutical databases.
CADD UNIT V - Molecular Modeling: Introduction to molecular mechanics and quantum mechanics.Energy Minimization methods and Conformational Analysis, global conformational minima determination.
SAR versus QSAR, History and development of QSAR, Types of physicochemical
parameters, experimental and theoretical approaches for the determination of
physicochemical parameters such as Partition coefficient, Hammet’s substituent
constant and Taft’s steric constant. Hansch analysis, Free Wilson analysis, 3D-QSAR
approaches like COMFA and COMSIA.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
How to Create Map Views in the Odoo 17 ERPCeline George
The map views are useful for providing a geographical representation of data. They allow users to visualize and analyze the data in a more intuitive manner.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
1. General method of the preparation of
Bacterial Infections, Toxoids, Viral vaccine, Antitoxins,
Serum-immune blood derivatives and
other products relative to immunity.
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-1 1
CO3.1
Noida Institute of Engineering and Technology
(Pharmacy Institute) Greater Noida
Abhijit Debnath
Asst. Professor
NIET, Pharmacy
Institute
Unit: 3
Subject Name: Biotechnology
(BP605T)
Course Details
(B. Pharm 6th Sem)
2. General Method of
the Preparation of
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-1 2
Bacterial infections,
Toxoids,
Viral vaccine,
Antitoxins,
Serum-immune blood derivatives and
other products relative to immunity.
CO1.1
Noida Institute of Engineering and Technology
(Pharmacy Institute) Greater Noida
3. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
3
A vaccine is a biological preparation that provides
active acquired immunity to a particular
infectious disease.
A vaccine typically contains an agent that
resembles a disease-causing microorganism and
is often made from weakened or killed forms of
the microbe, its toxins, or one of its surface
proteins.
VACCINE CO3.2
4. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
4
The agent stimulates the body's immune system to
recognize the agent as a threat, destroy it, and to further
recognize and destroy any of the microorganisms
associated with that agent that it may encounter in the
future. Vaccines can be prophylactic (to prevent or
ameliorate the effects of a future infection by a natural or
"wild" pathogen), or therapeutic
VACCINE CO3.2
5. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
5
VACCINE CO3.2
A vaccine is a biological preparation that provides active acquired immunity to
a particular infectious disease.
A vaccine typically contains an agent that resembles a disease-causing
microorganism and is often made from weakened or killed forms of the
microbe, its toxins, or one of its surface proteins.
The agent stimulates the body's immune system to recognize the agent as a
threat, destroy it, and to further recognize and destroy any of the
microorganisms associated with that agent that it may encounter in the future.
Vaccines can be prophylactic (to prevent or ameliorate the effects of a future
infection by a natural or "wild" pathogen), or therapeutic (e.g., vaccines
against cancer, which are being investigated)
6. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
6
VACCINE CO3.2
8. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
8
GENERATION OF VACCINES CO3.2
• First generation or traditional vaccines
-live or fixed whole pathogens
• Second generation vaccines
-the native protein antigens purified from the pathogen.
• Third-generation vaccines
-DNA plasmids capable of expressing the sequence of the most important
pathogen protein antigens in the host.
9. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
9
GENERATION OF VACCINES CO3.2
10. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
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GENERATION OF VACCINES CO3.2
11. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
11
HOW VACCINE WORKS? CO3.2
12. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
12
HOW VACCINE WORKS? CO3.2
13. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
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VACCINE PREPRATION CO3.2
14. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
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VACCINE PREPRATION CO3.2
15. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
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HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
16. Follow anyone of these approach:
• Inactivated
• Attenuated
• Toxoid
• Subunit
• Conjugate
• Experimental
• Valence
• Heterotypic
• First generation or traditional vaccines: live or fixed whole pathogens
• Second generation vaccines: native protein antigens purified from the
pathogen.
• Third-generation vaccines : DNA plasmids capable of expressing the
sequence of the most important pathogen protein antigens in the host.
Or
HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
17. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
17
HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
18. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
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STORAGE CONDITIONS FOR VACCINES CO3.2
19. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
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DIFFERENCE BETWEEN VACCINE AND DRUGS CO3.2
20. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 2
0
DIFFERENCE BETWEEN VACCINE AND DRUGS CO3.2