Biotechnology combines biology and technology to modify or make products. Karl Krkey is considered the father of biotechnology for describing using biological processes to boost agricultural production in 1919. Some early uses of biotechnology principles include making bread and curd 4000 BC and wine/beer 6000 BC. Major fields include animal, medical, industrial, and environmental biotechnology. Pharmaceutical biotechnology is the science of producing biological drugs using microorganisms, cells, or tissues and includes cytokines, enzymes, hormones, vaccines, monoclonal antibodies, and drug delivery applications.

1. SJM College of Pharmacy,
Chitradurga
Prepare By,
AdarshaBP
Ass Professor(Pharmacognosy)
SJM College of Pharmacy
1
PHARMACEUTICAL
BIOTECHNOLOGY

2. Biotechnology with reference to
Pharmaceutical Sciences.
Introduction: Hisory
Biotechnology Biology + Technology
Defn:-
Any Technological application that uses biological
system, living organisms, cells, tissues, explants or
derivatives thereof, to make or modify products or
process for specific uses.

3. ‘Karl Krkey’ Father of
Biotechnology. Hungarian
Agricultural Engineer in 1919, He
publish the book called
Biotechnology of Meat, fat, & Milk
production in an agricultural large-
scale farm, he described an
agricultural technology based on
converting raw materials into more
useful product in order to cause a
boom in agricultural production.

4. • Bread & Curd were prepared in 4000BC
• Yeast-Wine and beer were prepared in 6000BC
• Historical records the 1st biotechnology principles were
used around 6000 BC
• 20th Century- Applied microbiology & Industrial
fermentation & Genetic engineering
• Cohen & Boyer -1973- Introduced desired gene of one
organism to another organism & clone the new genes
by r-DNA Technology.

7. • Major fields of Biotechnology:
1. Animal biotechnology
2. Medical biotechnology
3. Industrial biotechnology
4. Environmental biotechnology

8. PHARMACEUTICAL BIOTECHNOLOGY:
Pharmaceutical science + Biotechnology
Defn- Science that covers all the technology
required for the production, Manufacturing of
Biological drugs.
By the use of Microorganism, Macroscopic organism
or tumour cells & Leukocytes.

9. Types of Biotech based pharmaceuticals:
1. Cytokines
2. Enzymes
3. Harmones
4. Clotting factor
5. Vaccines
6. Antisense technology
7. Drug Delivery
8. Monoclonal antibodies