This document summarizes common presenting symptoms of respiratory disorders including cough, sputum production, hemoptysis, breathlessness, chest pain, voice changes, and hiccups. For each symptom, it describes typical causes, associated features to ask about, and examples of patients presenting with that symptom. It provides clinical details to help physicians evaluate respiratory symptoms and determine potential etiologies.
Brief Presentation on clinical examination of Respiratory System with Report of Normal case
references:
macleod's clinical examination 13th edition
hutchinson clinical methods
R Alagappan - Manual of Practical Medicine, 4th Edition
Brief Presentation on clinical examination of Respiratory System with Report of Normal case
references:
macleod's clinical examination 13th edition
hutchinson clinical methods
R Alagappan - Manual of Practical Medicine, 4th Edition
Cardiology 1.2. Dyspnea - by Dr. Farjad IkramFarjad Ikram
Introduction to one of the most common symptoms that can represent a wide range of diseases, from benign to life-threatening, covering number of systems including gastrointestinal, cardiovascular, pulmonary, musculoskeletal and psychiatric.
Template design credits - http://www.slidescarnival.com
Respiratory System Analysis & Diagnosis AssessmentDrArulSelvan
Conducting a clinical examination is far better than writing a clinical investigation.
Developing a knowledge of successful scrutiny rather than laboratory investigations is vital for a physician in order to diagnose and treat the patient.
A member on Docplexus had a query on hirsuitism.
I have uploaded simple under graduate level lecture on Hirsuitism and Cong Adr Hyperplasia, which should give a simple and lucid overview of the distressing condition.
Several treatment options are available. Never forget to tell the patient that benefits will begin in 3 months time or so, otherwise they will run from clinic to clinic without relief.
Congenital Adr Hyperplasia (CAH) can appear at any age from birth to puberty where it can lead to ambiguous genitalia. It is due to absolute or relative deficiency of 17 Hydroxylase or 21 Hydroxylase enzyme.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Female, 45 years, Nurse,
• Fever and weight loss X 2 months
• Productive cough X 2 months
• Blood in sputum X 2 days
3. Male, 18 year, Medical student
• Fever X 2 days
• Sore throat and running nose X 1 day
• Dry and painful cough X 1 day
4. 55 year old soldier, Smoker
• Breathlessness and wheezing
• Productive Cough- more in the mornings
• Yellow sputum, approx 1 cupful X 1 week
• Similar problem every winter for over 15 years
that takes months to clear up.
• Mild symptoms persist throughout the year
5. Female, 50 years, Army wife
• Dry, distressing cough X 15 days
• Recently started on treatment for high BP
Tab Indapamide and Tab Enalapril
6. Why do patients consult ?
–Discomfort
–Interference with normal life
–Fear/ concern
7. 1. Cough
• Explosive expiration against a closed glottis-
Purpose- clearance of airways
Protective Superficial Reflex
• Afferent- Trigeminal, Glossopharyngeal, Sup
Laryngeal (Vagus)
• Efferent- Recurrent Laryngeal (Vagus) and
Spinal nerves
12. 60 year old female in C4 ward
• Progressive neurological illness X 2 months
• Weakness all 4 limbs
• Difficulty in swallowing
• Weakness of trunkal muscles
• Ineffective cough
13. Baby boy, 2 years
• Breathlessness and cough 1 hour ago
• Loud and noisy breathing since then
• Blue discoloration of skin X 10 minutes
• Was playing with toys unattended when this
happened
15. Male, 35 years, Alcoholic
• Low grade fever and weight loss X 1 Month
• Cough X 1 month
• sputum production X 15 days
• Sputum is purulent, blood tinged, foul
smelling. More while lying on the left side
19. 45 year old male, Smoker
• Change of voice X 1 month
• Worsening cough X I month
• Blood in sputum X 2 days
20. Causes of Hemoptysis
Site Common Causes Rare Causes
Tracheo bronchial Carcinoma
Bronchitis
Bronchiectasis
Adenoma
Foreign body
Parenchyma TB & Chronic Pneumonia
Acute Pneumonia
Lung abscess
Parasites
Trauma
Actinomycetes
Mycetoma
Lung Vasculature Infarction
PAN
Good Pasteur’s syndrome
Idiopathic pulmonary
hemosiderosis
CVS Disease Ac LVF
MS
Aortic Aneurysm
Blood Disorders Leukemia
Hemophilia
Anticoagulants
21. Questions ?
• Where from
• How much
• Single episode/ multiple
• Other sites
• Other complaints
• Pre existing disease
• Age group
• Occupation
• Injury
• Drugs
22. 4. Breathlessness
Mechanism is complex
• Sensory endings stimulation
• Work of breathing (muscles)
• Small airway obstruction
• Chemoreceptor stimulation (acidosis)
23. 70 year old male, non smoker
• Previously an employee of Union Carbide
factory in Bhopal
• Progressively worsening breathlessness for 29
years
• Intermittent respiratory infections
24. 30 year old HIV Positive,
• Dry Cough X 3 weeks
• Progressive Breathlessness X 2 weeks
• Moderate Fever and weight loss X 2 weeks
• Last CD4 200 cells
26. 40 year old postman, cycling every
day, non smoker
• Sudden onset and worsening by the minute-
Breathlessness and Chest pain X 1 hour
• Cyanosed
• Percussion-
27. Acute Severe Breathlessness
• Pulmonary Edema
• Massive Pulmonary Embolism
• Acute Severe Asthma
• Acute Exacerbation of COPD
• Severe Pneumonia
• Tension Pneumothorax
• Foreign body/ mucous plug
• Epiglottitis (children)
• Metabolic Acidosis
• Psychogenic
28. Questions ?
• Symptom Scale
• Precipitating event
• Associated complaints
• Pre existing disease
• Age group
• Occupation