Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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history taking in respiratory medicine.pptx
1. HISTORY TAKING & GENERAL PHYSICAL
EXAMINATION OF RESPIRATORY SYSTEM
Presented by:
Dr.Sachin Singh
1st year resident
Pulmonary Medicine
PDU Medical College
Churu, Rajasthan
2. Scheme of history taking
• Demographic data
• Chief complains
• History of present illness
• Past medical history
• Personal history
• Family history
• Social and environmental history
4. Chief Complaint
• The chief complain is a brief narration
explaining why the patient sought health care
• Each symptom should be recorded separately
with its duration or date of initial occurrence
• Eg ; fever for last 15 days
cough for last 10 days
SOB for last 5 days
• Ideally symptom description are written in
patients own world
5. History of present illness
• The HPI is the narrative portion of the history
that describes chronological and detail of each
symptom listed in chief complain and its effect
on patient life.
• In HPI the following information should be
gather for each symptom
* Description of onset – Date , time, sudden
or gradual
*Setting- cause, circumstance or active
surrounding onset
6. *Location – where on the body problem located &
where it radiate
*Severity – how severe it is & how it affect day to
day activity
*Quantity – how much, how large or how many.
*Quality – unique properties like colour, texture,
odour, composition, sharp or throbbing.
*Frequency – How often it occur
*Duration – How long it last, whether it is
constant or intermittent.
*Course – whether it is better, worse or staying
the same.
7. *Associated symptoms – symptom from same
body system or other system that occur before with
or after problem.
*Aggravating factors – things that make it worse
such as certain position, weather, temperature,
anxiety & exercise.
*Relieving factors – certain position, hot or cold,
after taking rest or medication.
8. Past Medical History
• PMH is the total sum of patient health status
prior to the present problem
• Information recorded in past history include a
chronologic list of the following
Illness since birth
Major illness in the past
Past history of hospitalization
Past history of injuries & accidents
Past history of surgery
Allergic history
9. Family History
• To find heredofamilial disorder & focus on
patient lineage
• It is important in Bronchial asthma, allergic
rhinitis, collagen vascular disease, lung cancer
specially adenocarcinoma, cystic fibrosis.
10. Personal history
• Smoking
*There is strong relation b/w smoking & chronic
respiratory disease, respiratory infection, lung
cancer & cardiovascular diseases
*Consumption of cigarettes should be recorded in
pack year.
*One pack year is 20 cigarettes smoked each day
for one year.
• Alcohol
• Exposure to organic dust like coal, silica, asbestosis
• Exposure to pets or animals
11. Occupational history
• Record occupation that are known to relate to
respiratory disease
1. Pneumoconiosis – Coal workers
2. Asbestosis – Plumbers, Power station workers
3. Bagassosis – sugar mill workers
4. Byssinosis – cotton industry
12. Review of systems
• This information is obtained in head to toe review of all body system
1. General – Fever, weight loss, loss of appetite, lethargy
2. CVS – Chest pain, palpitation, SOB, orthopnea (breathlessness at
lying flat), leg swelling, dizziness.
3. Respiratory system – SOB, cough, hemoptysis, wheeze, chest
pain.
4. GIT – Nausea, vomiting, hematemesis, dysphagia, heartburn,
jaundice, abdominal pain, rectal bleed, tenesmus.
5. Genitourinary system – Dysuria, frequency, terminal dribbling,
urethral discharge
6. Neurological system – Headache, dizziness, LOC, seizures,
numbness, tingling, weakness.
14. Cough
• Reflex act of forceful expiration against a closed
glottis generating positive intrathoracic pressure
• Aim is to clean the airway
• History should cover the duration & characteristics
of cough whether it is DRY or PRODUCTIVE of
sputum or blood
• Provocative factor i.e. cold, smoke, change in
posture or eating
15. • Accompanying symptom to find out likely cause
1. Running nose and sore throat- post nasal drip
2. Fever, chills & pleuritic chest pain- pneumonia
3. Heartburn – GERD
4. Weight loss & night sweats – chronic infection or tumor
5. Choking sensation & difficulty in swallowing while eating or
drinking – aspiration
Acute cough (< 3 weeks)
1. URTI (viral, sinusitis)
2. Pneumonia
3. Pulmonary embolism
4. Congestive cardiac failure
5. Allergic rhinitis
6. Exacerbation of asthma and COPD
21. Dyspnea
• Dyspnea is an unpleasant or uncomfortable awareness of breathing.
• It occur due to an imbalance b/w neurological stimulus & mechanical
changes that occur in the lung & chest wall resulting in mismatch of
ventilation & its demand.
Onset
Duration
Aggravating & releaving factor
Postural variation
Diurnal variation
22. Onset
• Within minutes
1. Pneumothorax
2. Pulmonary embolism
3. Inhaled foreign body
4. Laryngeal oedema
5. Left heart failure
• Hours to days
1. ARDS
2. Bronchial asthma
3. Pneumonia
• Weeks to month
1. COPD
2. Interstitial lung disease
3. Pleural effusion
4. Anaemia
5. Thyrotoxosis
25. • Hemoptysis
is coughing out blood from respiratory tract,
mainly the lungs
Types
1. Frank – expectoration of blood only
2. Spurious – secondary to URTI above the level of larynx
3. Pseudo hemoptysis – due to pigment produce by gram
negative bacteria
Severity
1. Mild - <100 ml /day
2. Moderate – 100 to 150 ml/day
3. Severe – up to 200 ml/day
4. Massive - >600 ml/day
26. Chest pain
• Chest pain may have its origin from disorders of
chest wall, pleura, lung, heart, great vessels,
oesophagus and subdiaphragmatic structures.
• h/o chest pain include – duration, location,
radiation to other area and character (heaviness,
tearing, burning, stabbing, sharp niddle like, merely
discomfort )
• Precipitating factors
• Associated symptoms
i.e. leg pain & swelling may point to DVT & pulmonary
embolism.
29. Physical examination
• Begins with assessment of general appearance, mental faculty & breathing pattern
• An anxious look indicate acute disease
• While presence of fatigue & cachexia point to chronic disease or malignancy
• A plethoric appearance in polycythemia ( mc in chronic lung disease and SVC
obstruction)
• Look at tongue, soft palate and nail bed for cyanosis, anaemia or polycythemia
• Fingers for clubbing
• Face, neck, hand & feet for oedema (generalised, localised, differential)
• Neck for lymphadenopathy or abnormal pulsation
• Record vital sign
1. Pulse – rate, rhythm, character
2. Respiration – type, rate & regularity
3. Blood pressure
4. temperature
30. • Breathing pattern
normal breathing is quiet with frequency of 12-
18/min
Tachycardia seen in – anxiety, anaemia, restrictive lung disease,
pulmonary HTN and hypoxia of any etiology
Bradypnea seen in – drug overdose & CNS lesion
Noisy breathing indicate narrowing of central airway in
carcinomatous lesion of vocal cord or trachea
Wheezing breath sound audible to unaided ears- narrowing of
intrathoracic airway i.e. asthma
Periodic breathing pattern – cheyne -stokes & biots breathing
associated with Lt heart failure & CNS lesion
In Kussmaul breathing – the depth of respiration is increased more
than rate mc associated with severe metabolic acidosis
31. Cyanosis
• Cyanosis is bluish discoloration of tongue & soft
palate
Central cynosis Peripheral cynosis
due to arterial hypoxia
May occur due to severe
chronic hypoxia of pulmonary
or cardiac origin and often
associater with polycythemia
due to low blood flow
Often occur with oedema
affect neck, face & upper limb
& indicate SVC obstraction
32. Clubbing
• Bulbous enlargement of terminal phalanges early changes consist of
thickening phalanges of fibroelastic tissue or nail bed
• detected by loss of normal angle b/w base of nail bed & adjacent
dorsal surface of figures
• Demonstrated best when viewed from side
33.
34. Lymphadenopathy
• Is abnormal enlargement of LN at neck, axilla, groin
• Note down number, size, consistency & fixity of LN
to each other, to underlaying tissue or overlying
skin
• Large fixed massive indicate – Metastasis
• Firm & matted nodes – tuberculosis
• LN in Hodgkin's lymphoma are classically described
as large, soft, rubbery in nature
37. Inspection
• Appearance, shape, size of chest
• Normal chest is b/l symmetrical & elliptical in cross section
But in disease it may be asymmetrical
1. Generalised or localised flattening of fullness in congenital disorder of lung,
plura, ribs, vertebra or sternum
Abnormal shape – rickets
Pectus carinatum (Pigeon chest) – localised prominence of sternum &
adjacent ribs
Pectus excavation (funnel chest) – localised depression of sternum & adjacent
ribs
Kyphosis – forward bending
Scoliosis – lateral banding
Flattening – decrease anteroposterior diameter
Hyperinflation or barrel shape – increase anteroposterior diameter
Observe for scar, injury mark, lumps & stains
38.
39.
40.
41. Movement of chest wall
• Normal both side of chest moves equally
• Decrease or absent movement on one side may
indicate disease of chest wall, pleura or lung on that
side
1. Symmetrical decrease in movement – emphysema,
asthma, end stage diffuse pulmonary fibrosis
2. Intercostal recession (indrawing of i/c space) – in severe
upper airway obstruction (laryngeal or trachial tumour)
3. Inward movement of lower rib – in asthma &
emphysema
4. Accessory muscle of respiration – in emphysema
42. • Shift of mediastinum – observe for prominence of
the tendon of sternomastoid muscle at the
suprasternal notch
• The trachea shifted to side of prominence – positive
trail sign
• Indicates shift of upper mediastinum to the same
side – fibrosis or collapse
• To opposite side – in pleural effusion,
pneumothorax, lung mass
43. Palpation
• Palpation is done to confirm the finding of inspection.
• Begins at the part of chest showing swelling or where c/o pain to detect
1. Inflammatory oedema due to rib fracture, cellulitis, infected cyst or tumour.
2. Air – subcutaneous emphysema
3. Pus – abscess, empyema
4. Nodule – purpura, sarcoid nodule, metastatic nodule
• Access position of trachea in suprasternal notch & apex beat at lower chest wall
• Access for symmetry movement on both side
In general pathological side moves less
• Access with intercostal space on both side to confirm flattening of fullness
• Vocal fremitus is detected by placing the ulnar side of hand over the
equivalent area on the two side of patient chest when narrates 1,2,3
or 99
44. Percussion
• Compare the degree of resonance over the
equivalent area on the two side of chest
• Note fot the area of tenderness
• Stony dull percussion note – in pleural effusion
(more so when breath sound & vocal resonance
decrease)
• Hyperresonant note indicate pneumothorax (more
so when chest appear fuller & breath sound & vocal
resonance decrease or absent.
46. Auscultation
• Breath sound listen to lung sound for its character & quality over all
the parts of the chest wall on both side using the diaphragm of
stethoscope
• Breath sounds are vascular in character (low frequency rustling with
longer inspiration than expiration & without a pause in between)
over the healthy lung & best heared at base of lung.
• Bronchial breathing – high pitch blowing sound, heared during
inspiration & expiration & separate by brief pause, it is normal over
trachea & larynx.
* But if heared over chest wall it indicate consolidation.
• Breath sound decreased in intensity when
1. Fluid (effusion)
2. Air (pneumothorax)
3. Atelectasis
47.
48. Adventitious sounds
• Wheezes – continuos high pitch sound, often musical in character,
which arise from air moving in narrow airway e.g. asthma
- most marked during expiration & associated with prolong
expiratory sound.
• Crackles – are discontinuous “popping” or “bubble” sound, coarse,
gurgling sound are caused by secretion in large airway.
- heared during inspiration & expiration
• Fine crackles – heared during early inspiration in restrictive lung
disease (pulmonary oedema & pulmonary fibrosis
- produces due to sudden opening of small airways
• Rub is localised cracking or rubbing sound, often associated with
chest pain.
- heared during inspiration & expiration.
- indicates pleural inflammation.
49. Vocal resonance
• It is audible perception of the transmitted vibration
from vocal cord over the chest as patient narrate
1,2,3 or 99
- it increase in consolidation &
- decrease in atelectasis, pneumothorax & plural
effusion.