This document provides an assessment of the respiratory system through history taking and physical examination. It details important questions to ask patients regarding cough, dyspnea, hemoptysis and chest pain. The physical examination section covers inspection of the chest, palpation, percussion and auscultation. Specific abnormal findings are associated with various respiratory diseases such as consolidation, fibrosis, cavities, pleural effusions and pneumothorax. Breath sounds, additional sounds and mediastinal shifts are also described for different lung abnormalities.
Respiratory System Analysis & Diagnosis AssessmentDrArulSelvan
Conducting a clinical examination is far better than writing a clinical investigation.
Developing a knowledge of successful scrutiny rather than laboratory investigations is vital for a physician in order to diagnose and treat the patient.
Acute respiratory distress syndrome (ARDS) is a sudden and progressive form of acute respiratory failure in which the alveolar capillary membrane becomes damaged and more permeable to intravascular fluid resulting in severe dyspnoea, hypoxemia and diffuse pulmonary infiltrates.
Respiratory System Analysis & Diagnosis AssessmentDrArulSelvan
Conducting a clinical examination is far better than writing a clinical investigation.
Developing a knowledge of successful scrutiny rather than laboratory investigations is vital for a physician in order to diagnose and treat the patient.
Acute respiratory distress syndrome (ARDS) is a sudden and progressive form of acute respiratory failure in which the alveolar capillary membrane becomes damaged and more permeable to intravascular fluid resulting in severe dyspnoea, hypoxemia and diffuse pulmonary infiltrates.
This document summarizes community acquired pneumonia, its types , causes, organisms, CRUB-65 score, difference with atypical pneumonia, investigations, treatment and prevention.
How to present a Thoracic Case | IACTS SCORE 2020IACTSWeb
This presentation entails around the clinical presentation and description of thoracic lesions. It includes basic clinical examination, concepts around lesion and diagnosis, perioperative care, postoperative care, sequelae/ complications and management of specific lesions such as Pneumothorax, Empyema Thoracis, Bronchiectasis, Lung Abscess, Tuberculosis, Emphysema/ Bullae.
The presentation elucidates on the current modalities and management of neoplasms of the lung and oesophagus, as well as management of chest wall lesions.
This is courtesy of Prof. Srikrishna S.V, MS, MCh, FRCS(Ed.), FIACS. He currently serves as Professor and Senior Consultant of Thoracic Surgery at Narayana Institute of Cardiac Sciences, Bommasandra, Bengaluru.
This presentation is part of a video that belongs to the lecture series of IACTS SCORE 2020 held at the SSSIHMS Whitefield, Bengaluru between 7th and 8th March, 2020.
TUBERCULOSIS HAS BEEN EXCLUDED BECAUSE IN INDIA TUBERCULOSIS IS THE MOST COMMON CAUSE OF CHRONIC COUGH AND REST OTHER CAUSES OF CHRONIC COUGHS ARE IGNORED
This presentation addresses respiratory emergencies, and the approach to their management. These include: anaphylaxis, pneumonias, flail chest, pleural effusion, pulmonary embolism,
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
This document summarizes community acquired pneumonia, its types , causes, organisms, CRUB-65 score, difference with atypical pneumonia, investigations, treatment and prevention.
How to present a Thoracic Case | IACTS SCORE 2020IACTSWeb
This presentation entails around the clinical presentation and description of thoracic lesions. It includes basic clinical examination, concepts around lesion and diagnosis, perioperative care, postoperative care, sequelae/ complications and management of specific lesions such as Pneumothorax, Empyema Thoracis, Bronchiectasis, Lung Abscess, Tuberculosis, Emphysema/ Bullae.
The presentation elucidates on the current modalities and management of neoplasms of the lung and oesophagus, as well as management of chest wall lesions.
This is courtesy of Prof. Srikrishna S.V, MS, MCh, FRCS(Ed.), FIACS. He currently serves as Professor and Senior Consultant of Thoracic Surgery at Narayana Institute of Cardiac Sciences, Bommasandra, Bengaluru.
This presentation is part of a video that belongs to the lecture series of IACTS SCORE 2020 held at the SSSIHMS Whitefield, Bengaluru between 7th and 8th March, 2020.
TUBERCULOSIS HAS BEEN EXCLUDED BECAUSE IN INDIA TUBERCULOSIS IS THE MOST COMMON CAUSE OF CHRONIC COUGH AND REST OTHER CAUSES OF CHRONIC COUGHS ARE IGNORED
This presentation addresses respiratory emergencies, and the approach to their management. These include: anaphylaxis, pneumonias, flail chest, pleural effusion, pulmonary embolism,
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Respiratory system analysis & Diagnosis Assessment.pdf
1. Respiratory System
Analysis & Diagnosis
Assessment
1
Arul
Selvan.S
(Via Physiological
Aspects)
Third Professional Bachelor of Siddha Medicine &
Surgery
Government Siddha Medical
College
4. Cough
• Is it acute, subacute or chronic?
• Dry or Productive?
• Associated symptoms – fever, dyspnea,
chest pain, etc.?
• Risk factors – Smoking, environmental
factors, HIV, family h/o TB ?
• Symptoms of postnasal discharge,
GERD(Acid reflux)?
• Is the patient on ACE (Angiotensin
converting enzyme)inhibitor?
4
5. Acute cough <3 week's
• URI - Upper Respiratory Infection (URI or
Common Cold)
• Pneumonia
• Pulmonary embolism
5
6. Subacute cough (3- 8 weeks)
• Viral infections
• Post infectious
• Post nasal drip (Secretions from the nose that
drain down into the throat, causing congestion
and cough. Postnasal drip is usually caused by
allergies or the common cold)
• GERD
6
7. Chronic cough >8 weeks
• Pulmonary Tuberculosis
• Asthma
• COPD (Chronic obstructive pulmonary) disease
• Bronchogenic CA (Bronchogenic carcinoma begin as a small
focus of atypical epithelial cells within the bronchial mucosa.)
• Eosinophilic bronchitis (Airway inflammation due to
excessive mast cell recruitment)
• Post nasal drip
• GERD
7
11. Sputum :
Copious Amount
Bronchiectasis (condition in which the lungs airways become dama
making it hard to clear mucus.)
Lung Abscess - formation of cavities (more than 2 cm) containing necr
debris or fluid caused by microbial infection.
Necrotizing pneumonia (characterized by rapid progression
consolidation to necrosis and cavitation which may lead to pulmon
gangrene)
Alveolar cell CA
Empyema rupturing into bronchus
Postural variation
Lung Abscess & Bronchiectasis
11
12. Color of sputum
Yellow / Green — Bacterial infection
Black — coal worker pneumoconiosis (inhalation of dust
has caused interstitial fibrosis)
Pink frothy sputum — Pulmonary edema
Anchovy sauce ( Brown colored pus to compared this
one )— Ruptured amoebic liver abscess.
12
14. Dyspnea
• Within minutes
Pneumothorax
Pulmonary embolism
Inhalation of foreign body
Larnygeal edema
14
15. Dyspnea
• Hours to Days
ARDS (Acute respiratory distress syndrome)
Bronchial Asthma
Pneumoia
15
16. Dyspnea
• Weeks to Months
COPD
ILD - Interstitial Lung Disease (umbrella
term used for a large group of diseases
that cause scarring fibrosis of the lungs)
Pleural effusion
Anemia
Thyrotoxicosis
16
31. Inspection
• Symmetry of chest
• Position of Trachea
• Position of Apex impulse
• Movements of chest
• Accessory muscles
• Hollowness/Bulging/flattening/retraction/
crowding of ribs
• Kyphosis / Scoliosis.
• Scar/sinus/dilated veins.
31
37. Symmetry of chest--
• Spinal deformity — Kyphosis , Scoliosis.
• Bulging — Pleural effusion, Pneumothorax,
empyema necessitans (pleural space infections and
occurs when the infected fluid dissects spontaneously
into the chest wall from the pleural space.
• Flattening or depression — Fibrosis, Collapse.
37
41. Palpation
• Temperature
• Tenderness
• Position of trachea and apex beat
• Movement of chest
• Chest expansion
• Tactile vocal fremitus
• Others – flow in dilated veins,
subcutaneous emphysema.
41
42. Local pain / tenderness
• Empyema
• Infiltration of chest wall by tumor
• Osteomyelitis
• Costochondritis
• Herpes zoster
42
43. • Chest expention – Normal 2 inch
• < 1.5 inch..abnormal
• Chest movements are assessed in all areas.
• Inspection is better then palpation (for movements)
43
44. Chest expansion
General Restriction
• Extensive bilateral disorder
(abnormal accumulation of
surfactant-derived lipoprotein
compounds within the alveoli of
the lung)
• COPD
• ILD
• Ankylosing spondylitis
• Spinal deformity
Asymmetrical expansion
• Pleural effusion
• Pneumothorex
• Consolidation
• Collapse
• Fibrosis
44
45. Percussion
• Position of Patient : Sitting
• Anterior – Hands by the side
• Posterior – Hands over opposite shoulders
• Lateral – Hands over head.
45
51. Crackles
• Short, Explosive, Discontinuous Nonmusical sounds
• Bubbling / clicking /Explosive sounds
• Mechanism:
• Flow of air through secretions
• Sudden opening of a succession of small airways, due to rapid equalization
of pressure between 2 airway compartments
• Types—Fine—Arise from alveoli
Coarse—Arise from bronchus & Bronchioles.
51
52. Wheeze
ASTHMA
BRONCHITIS
VOCAL CORD DYSFUNCTION
FOREIGN BODY ASPIRATION
INFECTIONS – CROUP
LARYNGITIS
CONGESTIVE HEART
FAILURE
COPD
CYSTIC FIBROSIS
ILD
FIBROSING ALVELOLITIS
NOT ALL THAT WHEEZES IS ASTHMA
52
53. Pleural rub
• Friction of inflamed visceral & parietal pleural
surfaces against each other in respiration
• Creaking leathery sound
• During both phases
• Best heard at Lateral & Posterior bases of lung
53
54. Disease Mediastin
al shift
Percussion Breath
sounds
Added sounds
Consolida
tion
Midline Dull ↑
Bronchial
(tubular)
Crackles+ Rub+/-
Fibrosis Same side Impaired ↑/↓,
Bronchial
Crackles+
Collapse
(Major
bronchus
obstructio
n)
Same side Dull ↓ Vesicular None
Collapse
(Patent
bronchus)
Same side Dull ↑
Bronchial
tubular
Early – None Late
– Coarse crackles
54
55. Disease Mediastinal
shift
Percussi
on
Breath
sounds
Added sounds
Cavity Midline or
Same
side(if
associated
fibrosis)
Impaired ↑ Bronchial
(Cavernous)
Crackles +/-
Pleural
Effusion
Opposite
side
Stony
dull
↓ or Absent,
above level -
Bronchial
Pleural rub above
level
Pneumoth
orax
Opposite
side
Hyper-
resonant
↓ or Absent None
Emphyse
ma
Midline Hyper-
resonant
Low Wheeze +/-
But low
55