There are three main types of blood vessels: arteries, capillaries, and veins. Arteries carry oxygenated blood away from the heart and branch into smaller vessels before becoming capillaries. Capillaries allow for the exchange of nutrients, gases, and waste between blood and tissues. Veins carry deoxygenated blood back to the heart. Arteries have thick muscular walls to withstand high blood pressure from the heart, while veins have thinner walls and valves to prevent backflow of blood at low pressure.
Blood is carried through the body via blood vessels. An artery is a blood vessel that carries blood away from the heart, where it branches into ever-smaller vessels.
Blood is carried through the body via blood vessels. An artery is a blood vessel that carries blood away from the heart, where it branches into ever-smaller vessels.
Learning Objectives:
Compare and contrast the structure and function
of
Arteries
Veins
Capillaries
ulatory
system
Arteries
Arterioles
Capillaries
Venules
Veins
3 tunics
Lume
The Vessels
Functions:
Distribution of blood
Exchange of materials with tissues
Return of blood to the heart
Structure:
Most have the same basic structure:
– 3 layers surrounding a hollow lumen
Arteries are blood vessels that carry blood away from the heart. This blood is normally oxygenated, exceptions made for the pulmonary and umbilical arteries
There are three kinds of blood vessels: arteries, veins, and capillaries.
Each of these plays a very specific role in the circulation process/blood circulation.
Arteries transport blood away from the heart.
Veins return blood back toward the heart.
Capillaries surround body cells and tissues to deliver and absorb oxygen, nutrients, and other substances.
The capillaries also connect the branches of arteries and to the branches of veins.
The walls of most blood vessels have three distinct layers: the tunica externa, the tunica media, and the tunica intima.
Learning Objectives:
Compare and contrast the structure and function
of
Arteries
Veins
Capillaries
ulatory
system
Arteries
Arterioles
Capillaries
Venules
Veins
3 tunics
Lume
The Vessels
Functions:
Distribution of blood
Exchange of materials with tissues
Return of blood to the heart
Structure:
Most have the same basic structure:
– 3 layers surrounding a hollow lumen
Arteries are blood vessels that carry blood away from the heart. This blood is normally oxygenated, exceptions made for the pulmonary and umbilical arteries
There are three kinds of blood vessels: arteries, veins, and capillaries.
Each of these plays a very specific role in the circulation process/blood circulation.
Arteries transport blood away from the heart.
Veins return blood back toward the heart.
Capillaries surround body cells and tissues to deliver and absorb oxygen, nutrients, and other substances.
The capillaries also connect the branches of arteries and to the branches of veins.
The walls of most blood vessels have three distinct layers: the tunica externa, the tunica media, and the tunica intima.
The presentation that will unable to create a clear cut concept regarding the Vessels the vascular system of the human body. It will let you know about the arteries, veins, capillaries how the exchange of nutrients and other substance takes place..and many more things related to the vessels of the body.
Describe the difference between a. The pulmonary and systemic circula.pdfcalderoncasto9163
Describe the difference between a. The pulmonary and systemic circulation b. An artery and a
vein c. An atrium and a ventricle
Solution
a. Pulmonary and systemic circulation
The cardiovascular system comprise of two circulatory pathsways namely pulmonary and
sytemic circulation.The pulmonary circulation circuits through the lungs carrying the oxygenated
blood whereas the systemic circulation circuit through the rest of the body to provide oxygenated
blood to various body parts.
In the pulmonary circulation, blood travels through capillaries on the alveoli, air sacs in the lungs
allowing the gas exchange. Here, as blood flows, the size of the vessel decreases from artery to
arteriole, from vein to venuleand finally to capillaries,which serve as vessels for gas and nutrient
exchange.In the systemic circulation,the movement of blood takes place from the heart through
the body providing oxygen and nutrients to the tissues of the body while bringing back the
deoxygenated to the heart. Systemic and pulmonary circulation transition to the opposite to each
other. Systemic circulation is a much larger and higher pressure system than pulmonary
circulation.
Thus systemic circulation is the larger path that blood takes on, routing oxygenated blood around
the tissues of the body and deoxygenated blood from them back to the heart , while pulmonary
circulation is the smaller loop that blood takes in the lungs.
b. An artery and a Vein
Blood is circulated in the body through arteries, veins and capillaries in a closed circulatory
system.
All blood vessels leading from heart carrying oxygenated blood (except pulmonary artery) to
various organs of the body are called as arteries.
Whereas, vessels which carry deoxygenated blood (except pulmonary vein) from various organs
of the body to the heart are called as veins.
Arteries have thick elastic muscular walls and valves are absent, whereas, Veins have thin non-
elastic valves and valves are present to prevent bacl flow of blood.
c. An atrium and a Ventricle
There are 4 chambers in the heart; the atria refer to the upper chambers while the ventricles refer
to the lower chambers.
Atria (atrium) refers to the upper chambers of the heart that receive the impure blood from the
veins to send it to the ventricles.
Ventricles are small cavities or chambers that are present within the left chamber of the heart that
accepts blood from the arteries (left atrium) and then contracts to force into the aorta. Both right
and the left part of our heart has an atrium and one ventricle.
The walls of the ventricles are thicker, while that of the atria are thinner. They ventricles contain
valves to pump the blood in and out of the heart..
The first topic in the practical histology coarse for pharmacy students
In this lecture the student will be able to recognize the histological layers of the circulatory system parts such as veins and arteries and the similarities and differences between each layer
Human cardiovascular system, organ system that conveys blood through vessels to and from all parts of the body, carrying nutrients and oxygen to tissues and removing carbon dioxide and other wastes. It is a closed tubular system in which the blood is propelled by a muscular heart. Two circuits, the pulmonary and the systemic, consist of arterial, capillary, and venous components.
The primary function of the heart is to serve as a muscular pump propelling blood into and through vessels to and from all parts of the body. The arteries, which receive this blood at high pressure and velocity and conduct it throughout the body, have thick walls that are composed of elastic fibrous tissue and muscle cells. The arterial tree—the branching system of arteries—terminates in short, narrow, muscular vessels called arterioles, from which blood enters simple endothelial tubes (i.e., tubes formed of endothelial, or lining, cells) known as capillaries. These thin, microscopic capillaries are permeable to vital cellular nutrients and waste products that they receive and distribute. From the capillaries, the blood, now depleted of oxygen and burdened with waste products, moving more slowly and under low pressure, enters small vessels called venules that converge to form veins, ultimately guiding the blood on its way back to the heart.
Blood vessels: Arteries, Veins and CapillariesAmir Rifaat
It is one of the circulatory systems. This explains the roles of arteries, veins and capillaries. It also differentiate between the arteries, veins and capillaries. This slide also explained the pulmonary circuit and systemic curcuit. This is an interesting notes and easy to be understand.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
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6. • Transport blood to
the heart.
•Connect arterioles to
venules
•Transport blood away from the
heart
7. A R T E R IE
S
• Carry blood away from
the heart
• Branch into smaller
vessels arterioles
capillaries
• To transport blood
quickly & at high
pressure to the tissues.
• Arteries walls consist of
epithelial tissue, smooth
8. CAPILLARIES
• The sites for the exchange
of nutrients, respiratory
gases & waste products.
• Thin-walled blood vessels
which allow rapid gaseous
exchange to occur, only one-
cell thick.
• Capillaries venules veins
9. VEINS
• Transport blood back to the
heart
• Consist of epithelial tissue
surrounded by smooth
muscle (thinner than
arteries) & connective tissue
• Blood flows under low
pressure
• Have large lumens & valves
that maintain the one-way
flow of blood
10. Differences between arteries,
capillaries & veins
A r t e r ie s C a p il l a r ie s V e in s
Transport blood away Connect arterioles to Transport blood to the
from the heart venules heart
Transport oxygenated Act as the sites for Transport deoxygenated
blood (except the exchange of substances blood (except the
pulmonary artery) with the cells pulmonary vein)
Thick muscular wall Thinnest wall, one cell in Thinner wall
thickness
No valves except semi- No valves Valves present to prevent
lunar valves at the base of back flow of blood
the aorta & pulmonary
artery
Blood flows in pulse No pulses; pressure lower No pulses; blood flows
under high pressure than arteries but higher under lower pressure than
than veins arteries
